JP6082250B2 - 認知機能を改善するための方法および組成物 - Google Patents

認知機能を改善するための方法および組成物 Download PDF

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Publication number
JP6082250B2
JP6082250B2 JP2012552161A JP2012552161A JP6082250B2 JP 6082250 B2 JP6082250 B2 JP 6082250B2 JP 2012552161 A JP2012552161 A JP 2012552161A JP 2012552161 A JP2012552161 A JP 2012552161A JP 6082250 B2 JP6082250 B2 JP 6082250B2
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hydrate
acceptable salt
pharmaceutically acceptable
solvate
levetiracetam
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JP2013518914A (ja
JP2013518914A5 (https=
Inventor
ミケラ ギャラガー，
ミケラ ギャラガー，
レベッカ ハーバーマン，
レベッカ ハーバーマン，
ミン テン コー，
ミン テン コー，
Original Assignee
ザ・ジョンズ・ホプキンス・ユニバーシティー
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pest Control & Pesticides (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Agronomy & Crop Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012552161A 2010-02-09 2011-02-09 認知機能を改善するための方法および組成物 Active JP6082250B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30276010P 2010-02-09 2010-02-09
US61/302,760 2010-02-09
PCT/US2011/024256 WO2011100373A1 (en) 2010-02-09 2011-02-09 Methods and compositions for improving cognitive function

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015145092A Division JP2015187179A (ja) 2010-02-09 2015-07-22 認知機能を改善するための方法および組成物

Publications (3)

Publication Number Publication Date
JP2013518914A JP2013518914A (ja) 2013-05-23
JP2013518914A5 JP2013518914A5 (https=) 2014-03-27
JP6082250B2 true JP6082250B2 (ja) 2017-02-15

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Family Applications (6)

Application Number Title Priority Date Filing Date
JP2012552161A Active JP6082250B2 (ja) 2010-02-09 2011-02-09 認知機能を改善するための方法および組成物
JP2015145092A Withdrawn JP2015187179A (ja) 2010-02-09 2015-07-22 認知機能を改善するための方法および組成物
JP2017151664A Expired - Fee Related JP7057075B2 (ja) 2010-02-09 2017-08-04 認知機能を改善するための方法および組成物
JP2018112954A Withdrawn JP2018138618A (ja) 2010-02-09 2018-06-13 認知機能を改善するための方法および組成物
JP2020127966A Pending JP2020172552A (ja) 2010-02-09 2020-07-29 認知機能を改善するための方法および組成物
JP2022011736A Pending JP2022044797A (ja) 2010-02-09 2022-01-28 認知機能を改善するための方法および組成物

Family Applications After (5)

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JP2015145092A Withdrawn JP2015187179A (ja) 2010-02-09 2015-07-22 認知機能を改善するための方法および組成物
JP2017151664A Expired - Fee Related JP7057075B2 (ja) 2010-02-09 2017-08-04 認知機能を改善するための方法および組成物
JP2018112954A Withdrawn JP2018138618A (ja) 2010-02-09 2018-06-13 認知機能を改善するための方法および組成物
JP2020127966A Pending JP2020172552A (ja) 2010-02-09 2020-07-29 認知機能を改善するための方法および組成物
JP2022011736A Pending JP2022044797A (ja) 2010-02-09 2022-01-28 認知機能を改善するための方法および組成物

Country Status (9)

Country Link
US (3) US20110212928A1 (https=)
EP (1) EP2533645B1 (https=)
JP (6) JP6082250B2 (https=)
CN (2) CN109662964A (https=)
AU (1) AU2011215870B2 (https=)
BR (1) BR112012019923A2 (https=)
CA (1) CA2789014C (https=)
EA (2) EA037187B1 (https=)
WO (1) WO2011100373A1 (https=)

Families Citing this family (11)

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AU2007346591A1 (en) 2007-02-07 2008-08-14 Gosforth Centre (Holdings) Pty Ltd Treatment of ADHD
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AU2018208662B2 (en) * 2012-11-14 2020-07-23 The Johns Hopkins University Methods and Compositions for Treating Schizophrenia
US20140206667A1 (en) * 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
JP6433482B2 (ja) * 2013-03-15 2018-12-05 エージンバイオ， インコーポレイテッド 認知機能を改善するための方法および組成物
WO2014144663A1 (en) * 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
EP2968257A4 (en) * 2013-03-15 2016-08-31 Univ Johns Hopkins METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION
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CN116075302A (zh) * 2020-07-10 2023-05-05 艾吉因生物股份有限公司 GABAAα5激动剂和SV2A抑制剂的组合以及在认知损害的治疗中的使用方法
CN112957453B (zh) * 2021-03-04 2024-06-04 上海市精神卫生中心（上海市心理咨询培训中心） 胰岛素样生长因子结合蛋白2在制备治疗脑外伤引起的精神障碍的药物中的应用

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