JP6047609B2 - 糖尿病による脂肪肝及び腎肥大を抑制するための組成物及びその製造方法 - Google Patents

糖尿病による脂肪肝及び腎肥大を抑制するための組成物及びその製造方法 Download PDF

Info

Publication number
JP6047609B2
JP6047609B2 JP2015058547A JP2015058547A JP6047609B2 JP 6047609 B2 JP6047609 B2 JP 6047609B2 JP 2015058547 A JP2015058547 A JP 2015058547A JP 2015058547 A JP2015058547 A JP 2015058547A JP 6047609 B2 JP6047609 B2 JP 6047609B2
Authority
JP
Japan
Prior art keywords
group
fermented
test
composition
diabetes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2015058547A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015199707A (ja
Inventor
基二 門脇
基二 門脇
真敏 久保田
真敏 久保田
近藤　堯
堯 近藤
智子 川上
智子 川上
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Niigata University
Original Assignee
Niigata University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2015058547A priority Critical patent/JP6047609B2/ja
Application filed by Niigata University filed Critical Niigata University
Priority to TW104110062A priority patent/TWI664970B/zh
Priority to SG11201606837XA priority patent/SG11201606837XA/en
Priority to CN201580017620.9A priority patent/CN106470692B/zh
Priority to KR1020167030383A priority patent/KR101873141B1/ko
Priority to PCT/JP2015/059604 priority patent/WO2015152045A1/ja
Priority to TW108114756A priority patent/TWI721407B/zh
Priority to SG10201707707XA priority patent/SG10201707707XA/en
Publication of JP2015199707A publication Critical patent/JP2015199707A/ja
Application granted granted Critical
Publication of JP6047609B2 publication Critical patent/JP6047609B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Insects & Arthropods (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
JP2015058547A 2014-03-29 2015-03-20 糖尿病による脂肪肝及び腎肥大を抑制するための組成物及びその製造方法 Active JP6047609B2 (ja)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP2015058547A JP6047609B2 (ja) 2014-03-29 2015-03-20 糖尿病による脂肪肝及び腎肥大を抑制するための組成物及びその製造方法
SG11201606837XA SG11201606837XA (en) 2014-03-29 2015-03-27 Composition for suppressing fatty liver and renal hypertrophy due to diabetes and method for producing same
CN201580017620.9A CN106470692B (zh) 2014-03-29 2015-03-27 抑制由糖尿病引起的脂肪肝和肾肥大的组合物及其制造方法
KR1020167030383A KR101873141B1 (ko) 2014-03-29 2015-03-27 당뇨병에 의한 지방간을 억제하기 위한 조성물 및 당뇨병에 의한 신장 비대를 억제하기 위한 조성물
TW104110062A TWI664970B (zh) 2014-03-29 2015-03-27 抑制糖尿病所致之脂肪肝及腎肥大的組成物、及其製造方法
PCT/JP2015/059604 WO2015152045A1 (ja) 2014-03-29 2015-03-27 糖尿病による脂肪肝及び腎肥大を抑制する組成物及びその製造方法
TW108114756A TWI721407B (zh) 2014-03-29 2015-03-27 抑制糖尿病所致之脂肪肝及腎肥大的組成物
SG10201707707XA SG10201707707XA (en) 2014-03-29 2015-03-27 Composition for suppressing fatty liver and renal hypertrophy due to diabetes and method for producing same

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2014070644 2014-03-29
JP2014070644 2014-03-29
JP2015058547A JP6047609B2 (ja) 2014-03-29 2015-03-20 糖尿病による脂肪肝及び腎肥大を抑制するための組成物及びその製造方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016225242A Division JP6230681B2 (ja) 2014-03-29 2016-11-18 糖尿病による脂肪肝を抑制するための組成物及び糖尿病による腎肥大を抑制するための組成物

Publications (2)

Publication Number Publication Date
JP2015199707A JP2015199707A (ja) 2015-11-12
JP6047609B2 true JP6047609B2 (ja) 2016-12-21

Family

ID=54240371

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015058547A Active JP6047609B2 (ja) 2014-03-29 2015-03-20 糖尿病による脂肪肝及び腎肥大を抑制するための組成物及びその製造方法

Country Status (6)

Country Link
JP (1) JP6047609B2 (zh)
KR (1) KR101873141B1 (zh)
CN (1) CN106470692B (zh)
SG (2) SG10201707707XA (zh)
TW (2) TWI721407B (zh)
WO (1) WO2015152045A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101884939B1 (ko) * 2016-10-24 2018-08-03 안동대학교 산학협력단 지방축적을 억제하는 효과가 있는 구인 추출물을 유효성분으로 함유하는 조성물
KR102283127B1 (ko) * 2018-06-19 2021-07-29 주식회사 엠디헬스케어 류코노스톡속 균주를 포함하는 간 기능 개선용 조성물
CN111208041A (zh) * 2020-01-10 2020-05-29 万邦德制药集团有限公司 一种银杏叶滴丸的制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5024844A (en) * 1987-08-18 1991-06-18 Eimei Company, Ltd. Process for the production of dried earthworm powder and antihyperlipemic, antidiabetic, antihypertensive and antihypotensive preparations containing dried earthworm powder as active ingredient
JPH0780778B2 (ja) * 1987-08-18 1995-08-30 株式会社エイメイ 糖尿病治療剤
JPH02193929A (ja) * 1989-01-23 1990-07-31 Eimei:Kk 糖尿病治療剤
JPH02215726A (ja) * 1989-02-15 1990-08-28 Eimei:Kk 糖尿病治療剤
JP3390052B2 (ja) 1993-07-30 2003-03-24 ニシハツ産業株式会社 海苔原藻中の異物検出及び除去装置
JP2763482B2 (ja) 1993-09-16 1998-06-11 ニスコ建設株式会社 組立治具
JPH0780778A (ja) 1993-09-17 1995-03-28 Ishikawajima Harima Heavy Ind Co Ltd レール締結ボルトのトルク管理方法およびその装置
JP2003267878A (ja) * 2002-03-12 2003-09-25 Nihon Yamaninjin Kenkyusho:Kk 糖尿病性合併症の予防又は治療剤及び健康食品
CN1218032C (zh) * 2002-10-11 2005-09-07 王凯 蚂蚁发酵酒及其发酵工艺
JP3896338B2 (ja) * 2003-03-26 2007-03-22 暁酵素産業株式会社 甘味料及びその製造方法
JP2004321087A (ja) * 2003-04-25 2004-11-18 Kinkado:Kk 健康食品及びその製造方法
JP3984952B2 (ja) * 2003-12-26 2007-10-03 堯 近藤 健康食品の製造方法
JP2006193489A (ja) * 2005-01-14 2006-07-27 Toyo Shinyaku:Kk 体脂肪蓄積抑制剤
WO2006093164A1 (ja) * 2005-02-28 2006-09-08 Osaka Prefecture ミミズ由来の成分を含むウイルス感染及び増殖阻害剤
JP4521447B2 (ja) * 2008-01-30 2010-08-11 株式会社 ミヤトウ野草研究所 酵素含有の健康食品の製造方法及び健康食品
JP5390589B2 (ja) * 2011-12-27 2014-01-15 農業生産法人株式会社 熱帯資源植物研究所 血管新生阻害剤
CN115067419A (zh) * 2016-04-25 2022-09-20 中润丰禾饲料有限公司 一种饲料添加剂的应用和蚯蚓发酵液的制备方法

Also Published As

Publication number Publication date
SG11201606837XA (en) 2016-09-29
JP2015199707A (ja) 2015-11-12
SG10201707707XA (en) 2017-10-30
TWI664970B (zh) 2019-07-11
WO2015152045A1 (ja) 2015-10-08
TWI721407B (zh) 2021-03-11
KR101873141B1 (ko) 2018-06-29
TW201625281A (zh) 2016-07-16
KR20170004977A (ko) 2017-01-11
CN106470692B (zh) 2019-12-03
CN106470692A (zh) 2017-03-01
TW201932127A (zh) 2019-08-16

Similar Documents

Publication Publication Date Title
Kassaian et al. Effect of fenugreek seeds on blood glucose and lipid profiles in type 2 diabetic patients
CN101128211B (zh) 翠叶芦荟提取物、制备翠叶芦荟提取物的方法和高血糖改善剂
Noce et al. Cardiovascular protection of nephropathic male patients by oral food supplements
JP6047609B2 (ja) 糖尿病による脂肪肝及び腎肥大を抑制するための組成物及びその製造方法
Mosquera et al. Antiurolithiatic activity of Boldoa purpurascens aqueous extract: An in vitro and in vivo study
Adewole et al. Effects of Ficus exasperata Vahl.(Moraceae) leaf aqueous extract on the renal function of streptozotocin-treated rats
Miao et al. Using collagen peptides from the skin of monkfish (Lophius litulon) to ameliorate kidney damage in high-fat diet fed mice by regulating the Nrf2 pathway and NLRP3 signaling
CN101686994B (zh) 水溶性纤维素衍生物制备用于预防或治疗代谢综合征的药物等的用途
JP6701583B2 (ja) 糖尿疾患の１型治療用組成物
El-Beltagy et al. Therapeutic role of Azadirachta indica leaves ethanolic extract against diabetic nephropathy in rats neonatally induced by streptozotocin
Al Malki et al. 6-shogaol protects against diabetic nephropathy and cardiomyopathy via modulation of oxidative stress/NF-κB pathway.
JP6230681B2 (ja) 糖尿病による脂肪肝を抑制するための組成物及び糖尿病による腎肥大を抑制するための組成物
Padhar et al. Clinical study of Arogyavardhini compound and lifestyle modification in management of metabolic syndrome: a double-blind placebo controlled randomized clinical trial
Ekpenyong et al. Phytoconstituents and diuretic activity of Cymbopogon citratus leaf infusions in humans
KR20180079920A (ko) 토사자 추출물을 유효성분으로 함유하는 간섬유화 또는 간경화 예방, 개선 또는 치료용 조성물
CN109846038A (zh) 一种降三高复方小分子肽功能食品及其制备方法
Pipitone et al. Red and golden tomato administration improves fat diet-induced hepatic steatosis in rats by modulating HNF4α, Lepr, and GK expression
KR20160141986A (ko) 홍삼 및 유산균을 함유하는 혈관질환을 예방, 개선 또는 치료하기 위한 조성물
Nada et al. Evaluation of Moringa oleifera leaves extract effects on streptozotocin-induced diabetic rats
Cheng et al. Anti‐apoptotic and pro‐survival effects of longan flower extracts on rat hearts with fructose‐induced metabolic syndrome
Abigail et al. Evaluation of Antidiabetic Effect of Crude Aqueous Extract of Nut, Leaf and Stem Parts of Vigna subterranae on Streptozotocin-Induced Diabetic Rats
Queen et al. Splenectomy in bile fistula dogs: Bile pigment overproduction, anemia and intoxication
CN106491922A (zh) 一种适用于气滞痰浊型高脂血症的中药配方药物及其胶囊剂
Adeyemi et al. Hibiscus Sabdariffa Reduces Renal Damage in Experimental Streptozotocin-induced Diabetes.
El-Sayed et al. Antidiabetes Effect of Aqueous Extract of leaves Lemongrass (Cymbopogon citratus) and its Leaves Powder on Diabetic Rats

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20151207

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20151207

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160115

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20160905

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160930

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20161024

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20161121

R150 Certificate of patent or registration of utility model

Ref document number: 6047609

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250