JP6043296B2 - 有効成分を投与するための経皮治療システム - Google Patents

有効成分を投与するための経皮治療システム Download PDF

Info

Publication number
JP6043296B2
JP6043296B2 JP2013543774A JP2013543774A JP6043296B2 JP 6043296 B2 JP6043296 B2 JP 6043296B2 JP 2013543774 A JP2013543774 A JP 2013543774A JP 2013543774 A JP2013543774 A JP 2013543774A JP 6043296 B2 JP6043296 B2 JP 6043296B2
Authority
JP
Japan
Prior art keywords
layer
active ingredient
polymer
therapeutic system
transdermal therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2013543774A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014503523A5 (enExample
JP2014503523A (ja
Inventor
ランガー，ブリッタ
シューラート，ビョルン
プリンツ，ハイケ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Luye Pharma AG
Original Assignee
Luye Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Luye Pharma AG filed Critical Luye Pharma AG
Publication of JP2014503523A publication Critical patent/JP2014503523A/ja
Publication of JP2014503523A5 publication Critical patent/JP2014503523A5/ja
Application granted granted Critical
Publication of JP6043296B2 publication Critical patent/JP6043296B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2013543774A 2010-12-14 2011-12-14 有効成分を投与するための経皮治療システム Active JP6043296B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10194968.3 2010-12-14
EP10194968.3A EP2468274B1 (de) 2010-12-14 2010-12-14 Transdermales therapeutisches System zur Verabreichung eines Wirkstoffs
PCT/EP2011/072812 WO2012080365A1 (de) 2010-12-14 2011-12-14 Transdermales therapeutisches system zur verabreichung eines wirkstoffs

Publications (3)

Publication Number Publication Date
JP2014503523A JP2014503523A (ja) 2014-02-13
JP2014503523A5 JP2014503523A5 (enExample) 2015-02-05
JP6043296B2 true JP6043296B2 (ja) 2016-12-14

Family

ID=43836835

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013543774A Active JP6043296B2 (ja) 2010-12-14 2011-12-14 有効成分を投与するための経皮治療システム

Country Status (25)

Country Link
US (2) US10660863B2 (enExample)
EP (2) EP2468274B1 (enExample)
JP (1) JP6043296B2 (enExample)
KR (1) KR101842309B1 (enExample)
CN (3) CN103269698B (enExample)
AU (2) AU2011343363B2 (enExample)
BR (1) BR112013014616B1 (enExample)
CA (2) CA3065240C (enExample)
CY (2) CY1116638T1 (enExample)
DK (2) DK2468274T3 (enExample)
EA (1) EA026520B1 (enExample)
ES (2) ES2545094T3 (enExample)
HK (1) HK1243336A1 (enExample)
HR (2) HRP20201880T1 (enExample)
HU (2) HUE027916T2 (enExample)
LT (1) LT2651410T (enExample)
MX (1) MX345344B (enExample)
MY (1) MY183873A (enExample)
PL (2) PL2468274T3 (enExample)
PT (2) PT2468274E (enExample)
RS (2) RS54173B1 (enExample)
SI (2) SI2468274T1 (enExample)
SM (2) SMT202000638T1 (enExample)
WO (1) WO2012080365A1 (enExample)
ZA (1) ZA201303965B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012000369A1 (de) * 2012-01-11 2013-07-11 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System mit Cholinesterase-Hemmer
DE102012016317A1 (de) * 2012-08-14 2014-02-20 Jenabatteries GmbH Redox-Flow-Zelle zur Speicherung elektrischer Energie
US20150196515A1 (en) * 2012-08-15 2015-07-16 Dow Coming Corporation Multi-Layer Drug Delivery System
WO2014111790A2 (en) * 2013-01-15 2014-07-24 Zydus Technologies Limited Stable transdermal pharmaceutical drug delivery system comprising rivastigmine
US20240082065A1 (en) * 2016-07-08 2024-03-14 Moteah Williams Waterproof and transparent wound barrier and method of manufacturing same
EP3501518B1 (en) 2016-08-22 2025-05-14 Kyukyu Pharmaceutical Co., Ltd. Transdermal patch of rivastigmine
JP7193863B2 (ja) * 2017-07-19 2022-12-21 帝國製薬株式会社 リバスチグミン含有経皮吸収型製剤
DE102018120506A1 (de) * 2017-10-20 2019-04-25 Amw Gmbh Stabilisiertes transdermales Darreichungssystem
DE102017127433A1 (de) * 2017-11-21 2019-05-23 Lts Lohmann Therapie-Systeme Ag TTS auf Basis von klebenden Weichmacher-Polymer-Matrices
CN111971032A (zh) * 2018-03-13 2020-11-20 罗曼治疗系统股份公司 包含有机硅丙烯酸杂化聚合物的透皮治疗系统
JP7170285B2 (ja) * 2018-05-17 2022-11-14 パナソニックＩｐマネジメント株式会社 生体貼付け用選択透過膜、経皮吸収キットおよび美容方法
ES2923891T3 (es) 2018-08-08 2022-10-03 Danapak Flexibles As Películas y láminas mejoradas para usarse en el envase de compuestos reactivos
KR102823139B1 (ko) 2018-08-31 2025-06-19 에스케이케미칼 주식회사 장기 투여용 리바스티그민 패취
KR102710072B1 (ko) 2018-08-31 2024-09-24 에스케이케미칼 주식회사 장기 투여용 리바스티그민 패취
EP3996693A1 (en) * 2019-07-09 2022-05-18 LTS Lohmann Therapie-Systeme AG Transdermal therapeutic system comprising an active agent-containing layer comprising an acrylic polymer and a skin contact layer comprising a silicone gel adhesive
CN113616625B (zh) * 2021-08-26 2023-05-30 大连科翔科技开发有限公司 一种卡巴拉汀的长效透皮贴剂
DE102021128912A1 (de) * 2021-11-05 2023-05-11 Lts Lohmann Therapie-Systeme Ag. Okklusives pflaster mit flexibler backing

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL195004C (nl) 1987-03-04 2003-11-04 Novartis Ag Fenylcarbamaat bevattend farmaceutisch preparaat.
CA2142871A1 (en) * 1992-08-25 1994-03-03 Jesus Miranda Printed transdermal drug delivery device
JPH0912448A (ja) * 1995-04-28 1997-01-14 Read Chem Kk 薬物放出制御型経皮吸収製剤
GB9800526D0 (en) 1998-01-12 1998-03-11 Ciba Geigy Ag Organic compounds
US6348210B1 (en) * 1998-11-13 2002-02-19 Alza Corporation Methods for transdermal drug administration
DE19918106A1 (de) 1999-04-22 2000-10-26 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern
DE10033853A1 (de) 2000-07-12 2002-01-31 Hexal Ag Transdermales therapeutisches System mit hochdispersem Siliziumdioxid
DE10103860B4 (de) * 2001-01-30 2004-12-23 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System für die Verabreichung carboxylgruppenhaltiger, nichtsteroidaler Antiphlogistika, sowie Verfahren zu seiner Herstellung
DE10141650C1 (de) * 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
DE10141652B4 (de) 2001-08-24 2011-04-07 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung
PL2216018T3 (pl) * 2004-10-21 2012-09-28 Durect Corp Transdermalne systemy dostarczania
US8252319B2 (en) * 2004-10-21 2012-08-28 Durect Corporation Transdermal delivery system for sufentanil
TWI389709B (zh) * 2005-12-01 2013-03-21 Novartis Ag 經皮治療系統
CN101351233A (zh) * 2005-12-30 2009-01-21 科洛普拉斯特公司 具有可塑的层作为皮肤接触表面的层状粘合构造
CN101304735A (zh) * 2006-01-12 2008-11-12 Lts勒曼治疗系统股份公司 用于挥发性和/或热不稳定的物质的经皮治疗体系
CN101460156B (zh) * 2006-05-08 2011-06-08 帝国制药株式会社 抗痴呆药的经皮吸收制剂
US9248104B2 (en) 2006-08-17 2016-02-02 Core Tech Solutions, Inc. Transdermal methods and systems for treating Alzheimer's disease
DE102006054731B4 (de) * 2006-11-21 2013-02-28 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System zur Verabreichung des Wirkstoffs Buprenorphin und Verwendung desselben in der Schmerztherapie
EP2167001A4 (en) 2007-07-10 2012-10-31 Agile Therapeutics Inc DEVICE FOR THE DERIVED ULTRASONIC WELDING
WO2009026135A2 (en) * 2007-08-17 2009-02-26 Alza Corporation Controlled transdermal bisoprolol delivery system
WO2009107478A1 (ja) * 2008-02-27 2009-09-03 久光製薬株式会社 貼付剤及び包装体
US20090291127A1 (en) * 2008-05-21 2009-11-26 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
JP2010126450A (ja) * 2008-11-25 2010-06-10 Lintec Corp 経皮吸収貼付剤
DK2515886T3 (en) * 2009-12-22 2018-06-14 Luye Pharma Ag Transdermal therapeutic system for administration of rivastigmine or derivatives thereof

Also Published As

Publication number Publication date
KR101842309B1 (ko) 2018-03-26
EA026520B1 (ru) 2017-04-28
CN103269698B (zh) 2017-07-14
ES2545094T3 (es) 2015-09-08
US20140323996A1 (en) 2014-10-30
CN113244199A (zh) 2021-08-13
PL2468274T3 (pl) 2015-11-30
EP2468274B1 (de) 2015-07-01
ES2836483T3 (es) 2021-06-25
EP2468274A1 (de) 2012-06-27
HUE052137T2 (hu) 2021-04-28
EP2651410B1 (de) 2020-10-14
ZA201303965B (en) 2014-09-25
EA201300704A1 (ru) 2014-01-30
CA2817461C (en) 2020-02-25
CY1116638T1 (el) 2017-03-15
KR20130129988A (ko) 2013-11-29
BR112013014616A2 (pt) 2016-09-20
CA2817461A1 (en) 2012-06-21
HRP20150881T1 (hr) 2015-09-25
SI2651410T1 (sl) 2021-01-29
AU2011343363A1 (en) 2013-06-20
PT2468274E (pt) 2015-09-21
DK2651410T3 (da) 2020-11-02
US10660863B2 (en) 2020-05-26
BR112013014616B1 (pt) 2021-12-21
RS61155B1 (sr) 2020-12-31
DK2468274T3 (en) 2015-08-31
CY1123712T1 (el) 2022-03-24
SI2468274T1 (sl) 2015-10-30
JP2014503523A (ja) 2014-02-13
HRP20201880T1 (hr) 2021-02-05
CA3065240A1 (en) 2012-06-21
AU2017213569A1 (en) 2017-08-31
WO2012080365A1 (de) 2012-06-21
SMT202000638T1 (it) 2021-01-05
MX345344B (es) 2017-01-26
PT2651410T (pt) 2020-12-15
CN107412202A (zh) 2017-12-01
AU2011343363B2 (en) 2017-06-08
AU2017213569B2 (en) 2019-04-11
SMT201500184B (it) 2015-09-07
EP2651410A1 (de) 2013-10-23
CA3065240C (en) 2022-02-15
RS54173B1 (sr) 2015-12-31
CN103269698A (zh) 2013-08-28
HK1243336A1 (zh) 2018-07-13
HUE027916T2 (en) 2016-11-28
PL2651410T3 (pl) 2021-03-08
MY183873A (en) 2021-03-17
MX2013005581A (es) 2013-08-26
US20200289426A1 (en) 2020-09-17
LT2651410T (lt) 2020-12-28

Similar Documents

Publication Publication Date Title
JP6043296B2 (ja) 有効成分を投与するための経皮治療システム
JP6083734B2 (ja) リバスチグミンまたはその誘導体を投与するための経皮治療システム
JP5632577B2 (ja) 貼付剤
KR20150032298A (ko) 경피 흡수 촉진제, 및 그것을 함유하는 첩부제
US10076502B2 (en) Transdermal therapeutic system for administering rivastigmine or derivatives thereof
TWI815983B (zh) 含阿申那平貼附劑
HK1187247B (en) Transdermal therapeutic system for administering an active substance
HK1187247A (en) Transdermal therapeutic system for administering an active substance
HK1170945A (en) Transdermal therapeutic system for administering rivastigmine or derivatives thereof
HK1170945B (en) Transdermal therapeutic system for administering rivastigmine or derivatives thereof

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20141212

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20141212

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20151113

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20151117

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20160210

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20160311

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20160413

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160517

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20160621

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160916

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20161018

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20161111

R150 Certificate of patent or registration of utility model

Ref document number: 6043296

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250