CN103269698B - 用于施用活性物质的经皮治疗系统 - Google Patents

用于施用活性物质的经皮治疗系统 Download PDF

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Publication number
CN103269698B
CN103269698B CN201180059614.1A CN201180059614A CN103269698B CN 103269698 B CN103269698 B CN 103269698B CN 201180059614 A CN201180059614 A CN 201180059614A CN 103269698 B CN103269698 B CN 103269698B
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China
Prior art keywords
layer
therapeutic system
active material
transcutaneous therapeutic
active substance
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CN201180059614.1A
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English (en)
Chinese (zh)
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CN103269698A (zh
Inventor
布丽塔·朗格尔
比约恩·舒拉德
海克·普林茨
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Luye Pharma AG
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Acino AG
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Priority to CN201710451001.1A priority Critical patent/CN107412202A/zh
Priority to CN202110438860.3A priority patent/CN113244199A/zh
Publication of CN103269698A publication Critical patent/CN103269698A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201180059614.1A 2010-12-14 2011-12-14 用于施用活性物质的经皮治疗系统 Active CN103269698B (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201710451001.1A CN107412202A (zh) 2010-12-14 2011-12-14 用于施用活性物质的经皮治疗系统
CN202110438860.3A CN113244199A (zh) 2010-12-14 2011-12-14 用于施用活性物质的经皮治疗系统

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10194968.3 2010-12-14
EP10194968.3A EP2468274B1 (de) 2010-12-14 2010-12-14 Transdermales therapeutisches System zur Verabreichung eines Wirkstoffs
PCT/EP2011/072812 WO2012080365A1 (de) 2010-12-14 2011-12-14 Transdermales therapeutisches system zur verabreichung eines wirkstoffs

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN201710451001.1A Division CN107412202A (zh) 2010-12-14 2011-12-14 用于施用活性物质的经皮治疗系统
CN202110438860.3A Division CN113244199A (zh) 2010-12-14 2011-12-14 用于施用活性物质的经皮治疗系统

Publications (2)

Publication Number Publication Date
CN103269698A CN103269698A (zh) 2013-08-28
CN103269698B true CN103269698B (zh) 2017-07-14

Family

ID=43836835

Family Applications (3)

Application Number Title Priority Date Filing Date
CN201180059614.1A Active CN103269698B (zh) 2010-12-14 2011-12-14 用于施用活性物质的经皮治疗系统
CN202110438860.3A Pending CN113244199A (zh) 2010-12-14 2011-12-14 用于施用活性物质的经皮治疗系统
CN201710451001.1A Pending CN107412202A (zh) 2010-12-14 2011-12-14 用于施用活性物质的经皮治疗系统

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN202110438860.3A Pending CN113244199A (zh) 2010-12-14 2011-12-14 用于施用活性物质的经皮治疗系统
CN201710451001.1A Pending CN107412202A (zh) 2010-12-14 2011-12-14 用于施用活性物质的经皮治疗系统

Country Status (25)

Country Link
US (2) US10660863B2 (enExample)
EP (2) EP2468274B1 (enExample)
JP (1) JP6043296B2 (enExample)
KR (1) KR101842309B1 (enExample)
CN (3) CN103269698B (enExample)
AU (2) AU2011343363B2 (enExample)
BR (1) BR112013014616B1 (enExample)
CA (2) CA2817461C (enExample)
CY (2) CY1116638T1 (enExample)
DK (2) DK2468274T3 (enExample)
EA (1) EA026520B1 (enExample)
ES (2) ES2545094T3 (enExample)
HK (1) HK1243336A1 (enExample)
HR (2) HRP20201880T1 (enExample)
HU (2) HUE027916T2 (enExample)
LT (1) LT2651410T (enExample)
MX (1) MX345344B (enExample)
MY (1) MY183873A (enExample)
PL (2) PL2468274T3 (enExample)
PT (2) PT2468274E (enExample)
RS (2) RS54173B1 (enExample)
SI (2) SI2468274T1 (enExample)
SM (2) SMT202000638T1 (enExample)
WO (1) WO2012080365A1 (enExample)
ZA (1) ZA201303965B (enExample)

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DE102012000369A1 (de) * 2012-01-11 2013-07-11 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System mit Cholinesterase-Hemmer
DE102012016317A1 (de) * 2012-08-14 2014-02-20 Jenabatteries GmbH Redox-Flow-Zelle zur Speicherung elektrischer Energie
WO2014028049A1 (en) * 2012-08-15 2014-02-20 Dow Corning Corporation Multi - layer transdermal drug delivery system
WO2014111790A2 (en) * 2013-01-15 2014-07-24 Zydus Technologies Limited Stable transdermal pharmaceutical drug delivery system comprising rivastigmine
US20240082065A1 (en) * 2016-07-08 2024-03-14 Moteah Williams Waterproof and transparent wound barrier and method of manufacturing same
WO2018038022A1 (ja) 2016-08-22 2018-03-01 救急薬品工業株式会社 貼付剤
EP3656383A4 (en) * 2017-07-19 2021-05-19 Teikoku Seiyaku Co., Ltd. RIVASTIGMIN-CONTAINING PERCUTICAL ABSORPTION PREPARATION
DE102018120505A1 (de) * 2017-10-20 2019-04-25 Amw Gmbh Verhinderung der Kristallisation von Wirkstoffen in transdermalen Darreichungssystemen
DE102017127433A1 (de) * 2017-11-21 2019-05-23 Lts Lohmann Therapie-Systeme Ag TTS auf Basis von klebenden Weichmacher-Polymer-Matrices
BR112020018300A2 (pt) * 2018-03-13 2020-12-22 Lts Lohmann Therapie-Systeme Ag Sistema terapêutico transdérmico compreendendo um polímero híbrido de silicone e acrílico
CN111885992B (zh) * 2018-05-17 2023-12-08 松下知识产权经营株式会社 生物体贴附用选择性透过膜、透皮吸收套件和美容方法
ES2923891T3 (es) 2018-08-08 2022-10-03 Danapak Flexibles As Películas y láminas mejoradas para usarse en el envase de compuestos reactivos
KR102823139B1 (ko) 2018-08-31 2025-06-19 에스케이케미칼 주식회사 장기 투여용 리바스티그민 패취
KR102710072B1 (ko) 2018-08-31 2024-09-24 에스케이케미칼 주식회사 장기 투여용 리바스티그민 패취
WO2021005118A1 (en) * 2019-07-09 2021-01-14 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system comprising an active agent-containing layer comprising an acrylic polymer and a skin contact layer comprising a silicone gel adhesive
CN113616625B (zh) * 2021-08-26 2023-05-30 大连科翔科技开发有限公司 一种卡巴拉汀的长效透皮贴剂
DE102021128912A1 (de) * 2021-11-05 2023-05-11 Lts Lohmann Therapie-Systeme Ag. Okklusives pflaster mit flexibler backing

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CN1354654A (zh) * 1999-04-22 2002-06-19 罗曼治疗系统股份公司 包括经中和的压力敏感性丙烯酸酯粘附剂的穿皮治疗系统
CN101312717A (zh) * 2005-12-01 2008-11-26 诺瓦提斯公司 透皮治疗系统
CN101460156A (zh) * 2006-05-08 2009-06-17 帝国制药株式会社 抗痴呆药的经皮吸收制剂

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HU201906B (en) 1987-03-04 1991-01-28 Sandoz Ag Process for producing phenyl-carbamate derivative and acid additional salts and pharmaceutical compositions containing them
JPH08502727A (ja) * 1992-08-25 1996-03-26 シグナス セラピューティック システムズ プリントされた経皮薬剤送達デバイス
JPH0912448A (ja) * 1995-04-28 1997-01-14 Read Chem Kk 薬物放出制御型経皮吸収製剤
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US6348210B1 (en) * 1998-11-13 2002-02-19 Alza Corporation Methods for transdermal drug administration
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DE10103860B4 (de) * 2001-01-30 2004-12-23 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System für die Verabreichung carboxylgruppenhaltiger, nichtsteroidaler Antiphlogistika, sowie Verfahren zu seiner Herstellung
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CN101312717A (zh) * 2005-12-01 2008-11-26 诺瓦提斯公司 透皮治疗系统
CN101460156A (zh) * 2006-05-08 2009-06-17 帝国制药株式会社 抗痴呆药的经皮吸收制剂

Also Published As

Publication number Publication date
CN103269698A (zh) 2013-08-28
LT2651410T (lt) 2020-12-28
HK1243336A1 (zh) 2018-07-13
WO2012080365A1 (de) 2012-06-21
JP2014503523A (ja) 2014-02-13
HUE027916T2 (en) 2016-11-28
CA3065240A1 (en) 2012-06-21
PL2651410T3 (pl) 2021-03-08
RS61155B1 (sr) 2020-12-31
SI2468274T1 (sl) 2015-10-30
US20200289426A1 (en) 2020-09-17
CA2817461A1 (en) 2012-06-21
MX345344B (es) 2017-01-26
PT2651410T (pt) 2020-12-15
US10660863B2 (en) 2020-05-26
SI2651410T1 (sl) 2021-01-29
EP2651410A1 (de) 2013-10-23
CA2817461C (en) 2020-02-25
PT2468274E (pt) 2015-09-21
ES2545094T3 (es) 2015-09-08
RS54173B1 (sr) 2015-12-31
EP2468274A1 (de) 2012-06-27
EP2468274B1 (de) 2015-07-01
EA201300704A1 (ru) 2014-01-30
MY183873A (en) 2021-03-17
MX2013005581A (es) 2013-08-26
JP6043296B2 (ja) 2016-12-14
BR112013014616B1 (pt) 2021-12-21
ZA201303965B (en) 2014-09-25
CY1116638T1 (el) 2017-03-15
KR20130129988A (ko) 2013-11-29
AU2017213569A1 (en) 2017-08-31
SMT202000638T1 (it) 2021-01-05
EA026520B1 (ru) 2017-04-28
DK2468274T3 (en) 2015-08-31
AU2011343363B2 (en) 2017-06-08
SMT201500184B (it) 2015-09-07
AU2017213569B2 (en) 2019-04-11
PL2468274T3 (pl) 2015-11-30
HRP20150881T1 (hr) 2015-09-25
CN113244199A (zh) 2021-08-13
CY1123712T1 (el) 2022-03-24
CN107412202A (zh) 2017-12-01
EP2651410B1 (de) 2020-10-14
ES2836483T3 (es) 2021-06-25
CA3065240C (en) 2022-02-15
US20140323996A1 (en) 2014-10-30
KR101842309B1 (ko) 2018-03-26
DK2651410T3 (da) 2020-11-02
BR112013014616A2 (pt) 2016-09-20
AU2011343363A1 (en) 2013-06-20
HRP20201880T1 (hr) 2021-02-05
HUE052137T2 (hu) 2021-04-28

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Address after: German Missbach

Applicant after: Green leaf Pharmaceutical Co., Ltd.

Address before: German Missbach

Applicant before: Acino AG

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