JP6025707B2 - 癌を治療する方法 - Google Patents
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- JP6025707B2 JP6025707B2 JP2013503875A JP2013503875A JP6025707B2 JP 6025707 B2 JP6025707 B2 JP 6025707B2 JP 2013503875 A JP2013503875 A JP 2013503875A JP 2013503875 A JP2013503875 A JP 2013503875A JP 6025707 B2 JP6025707 B2 JP 6025707B2
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| JP6025707B2 (ja) | 2010-04-06 | 2016-11-16 | エクソサイト セラピューティクス ピーティイー リミテッド | 癌を治療する方法 |
| JP6272765B2 (ja) * | 2012-10-01 | 2018-01-31 | 国立大学法人京都大学 | ナノゲル／エキソソーム複合体とｄｄｓ |
| WO2017112919A1 (en) * | 2015-12-23 | 2017-06-29 | The Trustees Of Columbia University In The City Of New York | Tissue-engineered three-dimensional model for tumor analysis |
| US10883083B2 (en) | 2013-08-02 | 2021-01-05 | The Trustees Of Columbia University In The City Of New York | Tissue-engineered three-dimensional model for tumor analysis |
| CN104726410B (zh) * | 2013-12-23 | 2019-09-17 | 浙江大学 | 一种具有免疫抑制功能的外排体及其应用 |
| CN105505772B (zh) * | 2015-12-07 | 2018-07-10 | 中国科学院苏州生物医学工程技术研究所 | 对单个外泌体进行裂解的装置 |
| US20190125848A1 (en) * | 2016-03-30 | 2019-05-02 | Dana-Farber Cancer Institute, Inc. | Dendritic cell-extracellular vesicle fusions and methods of using same |
| JP2018070572A (ja) * | 2016-10-24 | 2018-05-10 | 義之 小山 | 免疫治療システム |
| JP6613499B2 (ja) * | 2017-08-24 | 2019-12-04 | 学校法人藤田学園 | 細胞殺傷剤 |
| US12241091B2 (en) * | 2018-08-20 | 2025-03-04 | Institute Of Process Engineering, Chinese Academy Of Sciences | Method of making exosomes from tumor cell/antigen presenting cell hybrid cells |
| JP6635637B1 (ja) | 2018-11-22 | 2020-01-29 | 株式会社細胞治療技術研究所 | 免疫療法ワクチンの製造方法 |
| CN110036976B (zh) * | 2019-05-08 | 2021-12-07 | 华南农业大学 | 一种阻断鸡禽白血病病毒垂直传播的方法及其应用 |
| CN111759862A (zh) * | 2020-06-04 | 2020-10-13 | 江苏大学 | 干细胞外泌体在制备抗结肠炎恶化药物中的应用 |
| JP7160963B2 (ja) * | 2021-01-15 | 2022-10-25 | Ｖａｘｏｓｏｍｅ合同会社 | 細胞外粒子の製造方法 |
| JP7079901B1 (ja) * | 2021-08-24 | 2022-06-02 | Ｖａｘｏｓｏｍｅ合同会社 | 細胞外粒子の産生方法 |
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| US5605885A (en) * | 1988-05-05 | 1997-02-25 | Entremed, Inc. | Method for stimulating the immune system |
| EP0690671B1 (en) | 1993-03-23 | 2004-08-04 | Cbr Laboratories, Inc. | Method and apparatus for encapsulation of biologically-active substances in cells |
| DE4410136A1 (de) * | 1993-03-31 | 1994-10-06 | Boehringer Mannheim Gmbh | Tumorizide T-Lymphozyten |
| EP0698087A1 (en) * | 1993-05-14 | 1996-02-28 | Dr. L. Willems Instituut | Human t cell monoclone, process for its production and its use, diagnostic of infectious diseases, autoimmune diseases, t-cell mediated allergies and cancer |
| US5610013A (en) * | 1993-07-22 | 1997-03-11 | Ludwig Institute For Cancer Research | Method for diagnosing a disorder by determining expression of gage tumor rejection antigen precursors |
| US6773669B1 (en) | 1995-03-10 | 2004-08-10 | Maxcyte, Inc. | Flow electroporation chamber and method |
| US6074605A (en) | 1995-03-10 | 2000-06-13 | Entremed, Inc. | Flow electroporation chamber and method |
| US5720921A (en) | 1995-03-10 | 1998-02-24 | Entremed, Inc. | Flow electroporation chamber and method |
| US6090617A (en) | 1996-12-05 | 2000-07-18 | Entremed, Inc. | Flow electroporation chamber with electrodes having a crystalline metal nitride coating |
| FR2766205B1 (fr) | 1997-07-16 | 2002-08-30 | Inst Nat Sante Rech Med | Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede |
| US20020022036A1 (en) * | 2000-08-21 | 2002-02-21 | Riordan Neil H. | Method for inducing an anti-tumor and anti-cachexia immune response in mammals |
| US7029916B2 (en) | 2001-02-21 | 2006-04-18 | Maxcyte, Inc. | Apparatus and method for flow electroporation of biological samples |
| FR2827872A1 (fr) * | 2001-07-30 | 2003-01-31 | Roussy Inst Gustave | Vesicules membranaires de fluide biologique preleve in vivo, leur preparation et utilisation dans la stimulation d'une reponse immunitaire |
| EP1456345B1 (en) | 2001-08-22 | 2016-07-20 | Maxcyte, Inc. | Apparatus and method for electroporation of biological samples |
| AU2003277109A1 (en) | 2002-09-30 | 2004-04-23 | Maxcyte, Inc. | Apparatus and method for streaming electroporation |
| CN1446583A (zh) * | 2002-11-29 | 2003-10-08 | 帕弗瑞生物技术(北京)有限公司 | 一种肿瘤免疫治疗及预防性疫苗的组成、制备、应用方案 |
| WO2004053095A2 (en) * | 2002-12-10 | 2004-06-24 | Merix Bioscience, Inc. | In situ maturation of dendritic cells |
| MXPA05008687A (es) * | 2003-02-17 | 2005-10-05 | Mebiopharm Co Ltd | Remedio para cancer. |
| JP2006518219A (ja) * | 2003-02-18 | 2006-08-10 | マックスサイト インコーポレーティッド | 電気穿孔法による細胞への抗原の負荷方法 |
| US20060134067A1 (en) * | 2003-02-18 | 2006-06-22 | Maxcyte, Inc. | Loading of cells with antigens by electroporation |
| US8247231B2 (en) * | 2003-07-31 | 2012-08-21 | Wilson Constance N | Methods and compositions for producing antigenic responses |
| KR101131727B1 (ko) * | 2004-06-11 | 2012-03-28 | 가톨릭대학교 산학협력단 | ＣＥＡ-특이적인 세포독성 Ｔ세포를 생성하는 재조합 아데노바이러스 ＡｄＶＣＥＡ로 트랜스덕션된 수지상세포, 이를 포함하는 백신 및 약제학적 조성물 |
| US8338173B2 (en) * | 2005-08-11 | 2012-12-25 | University College Cardiff Consultants Limited | Preparation of antigen-presenting human γδ T cells and use in immunotherapy |
| JP4824389B2 (ja) * | 2005-10-28 | 2011-11-30 | 株式会社医学生物学研究所 | エプスタイン−バールウイルス感染細胞を特異的に攻撃する細胞傷害性ｔ細胞エピトープペプチド及びその用途 |
| CN101085349B (zh) * | 2006-06-09 | 2011-05-25 | 项雯华 | 囊泡导向的免疫细胞及其在制备抗肿瘤药物上的应用 |
| CN101883845B (zh) * | 2007-10-08 | 2015-06-10 | 英特瑞克斯顿股份有限公司 | 工程树突细胞及其在癌症治疗中的应用 |
| KR20090047290A (ko) * | 2007-11-07 | 2009-05-12 | 주식회사 바이오인프라 | 엑소좀 및 이를 함유한 암 백신 조성물 |
| KR101076879B1 (ko) | 2008-04-11 | 2011-10-25 | 주식회사 하이닉스반도체 | 셀프 부스팅을 이용한 플래시 메모리소자의 프로그램 방법 |
| EP2303319B1 (en) * | 2008-06-20 | 2016-10-05 | Duke University | Compositions, methods and kits for eliciting an immune response |
| JP6025707B2 (ja) | 2010-04-06 | 2016-11-16 | エクソサイト セラピューティクス ピーティイー リミテッド | 癌を治療する方法 |
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| CN102905534A (zh) | 2013-01-30 |
| CN102905534B (zh) | 2016-03-02 |
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| US20130202644A1 (en) | 2013-08-08 |
| EP2555627A4 (en) | 2013-10-23 |
| JP2017002054A (ja) | 2017-01-05 |
| EP2555627A1 (en) | 2013-02-13 |
| EP3238782A2 (en) | 2017-11-01 |
| US9107878B2 (en) | 2015-08-18 |
| EP3238782A3 (en) | 2018-01-03 |
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