JP6002763B2 - グラム陰性細菌の外膜小胞を、洗浄剤を含まずに生産するためのプロセス - Google Patents
グラム陰性細菌の外膜小胞を、洗浄剤を含まずに生産するためのプロセス Download PDFInfo
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- A—HUMAN NECESSITIES
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Landscapes
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| SI (1) | SI2729167T1 (pt) |
| TR (1) | TR201808206T4 (pt) |
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| CA2790167C (en) | 2010-03-30 | 2021-02-09 | Children's Hospital & Research Center Oakland | Factor h binding proteins (fhbp) with altered properties and methods of use thereof |
| CA2840096C (en) * | 2011-07-07 | 2021-07-06 | Bas VAN DE WATERBEEMD | A process for detergent-free production of outer membrane vesicles of a gram-negative bacterium |
| US10279026B2 (en) * | 2012-04-26 | 2019-05-07 | Glaxosmithkline Biologicals Sa | Antigens and antigen combinations |
| SG11201600334SA (en) | 2013-08-02 | 2016-02-26 | Children S Hospital & Res Ct Oakland | Non-naturally occurring factor h binding proteins (fhbp) and methods of use thereof |
| EP4074726A3 (en) | 2014-07-23 | 2022-11-23 | Children's Hospital & Research Center at Oakland | Factor h binding protein variants and methods of use thereof |
| KR101715366B1 (ko) * | 2014-09-04 | 2017-03-14 | 한국과학기술연구원 | 지질의 탈인산화용 조성물, 키트, 및 이를 이용한 탈인산화된 지질을 생산하는 방법 |
| AU2015352404A1 (en) * | 2014-11-28 | 2017-05-18 | Janssen Vaccines & Prevention B.V. | Meningitis B vaccine |
| WO2016193370A1 (en) | 2015-06-02 | 2016-12-08 | De Staat Der Nederlanden, Vert. Door De Minister Van Vws, Ministerie Van Volksgezondheid, Welzijn En Sport | Surface display of antigens on gram-negative outer membrane vesicles |
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| CN109071587B (zh) | 2016-01-28 | 2022-11-01 | 由卫生福利和体育大臣代表的荷兰王国 | 经修饰的六酰化奈瑟球菌lps |
| EP3544625A2 (en) | 2016-11-25 | 2019-10-02 | GlaxoSmithKline Biologicals S.A. | Immunogenic conjugates and use thereof |
| JP7311227B2 (ja) | 2017-03-13 | 2023-07-19 | イントラヴァック ビー．ブイ． | 低下した反応源性を有するｌｐｓを含むボルデテラワクチン |
| EP3720945A1 (en) * | 2017-12-04 | 2020-10-14 | De Staat der Nederlanden, vert. door de minister van VWS, Ministerie van Volksgezondheid, Welzjin en Sport | An improved process for producing outer membrane vesicles |
| TW202045192A (zh) * | 2019-02-22 | 2020-12-16 | 美商艾弗洛生物科技股份有限公司 | 細菌膜製劑 |
| JP2023525294A (ja) | 2020-05-08 | 2023-06-15 | イントラヴァック ベスローテン フェノーツハップ | クリックｏｍｖ |
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| CN115216478B (zh) * | 2022-06-01 | 2024-03-26 | 华南农业大学 | 一种禽多杀性巴氏杆菌内毒素减毒灭活疫苗菌株的构建方法及应用 |
| CN115976088B (zh) * | 2022-07-21 | 2023-09-19 | 深圳蓝晶生物科技有限公司 | 低内毒素含量的罗氏真养菌及其应用 |
| CN118240723A (zh) * | 2024-05-29 | 2024-06-25 | 上海羽冠生物技术有限公司 | 一种通过发酵产生细菌外膜囊泡的方法 |
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| US5997881A (en) | 1995-11-22 | 1999-12-07 | University Of Maryland, Baltimore | Method of making non-pyrogenic lipopolysaccharide or A |
| US6558677B2 (en) * | 1996-10-15 | 2003-05-06 | Wendell D. Zollinger | Vaccine against gram negative bacteria |
| EP1127137B2 (en) | 1998-11-03 | 2013-12-25 | De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur | Lps with reduced toxicity from genetically modified gram negative bacteria |
| GB0103170D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| EP2255826B1 (en) * | 2002-08-02 | 2016-04-13 | GlaxoSmithKline Biologicals S.A. | Neisserial vaccine compositions comprising a combination of antigens |
| GB0220194D0 (en) * | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| PT1748791E (pt) | 2004-05-11 | 2010-07-15 | Staat Der Nederlanden Vert Doo | Los de neisseria meningitidis lgtb utlizados como adjuvantes |
| RU2432962C2 (ru) * | 2005-01-27 | 2011-11-10 | Чилдрен'З Хоспитал Энд Рисерч Сентер Эт Окленд | Вакцины с использованием везикул на основе gna 1870 широкого спектра действия для профилактики заболеваний, вызываемых neisseria meningitidis |
| CA2840096C (en) * | 2011-07-07 | 2021-07-06 | Bas VAN DE WATERBEEMD | A process for detergent-free production of outer membrane vesicles of a gram-negative bacterium |
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| US9707286B2 (en) | 2017-07-18 |
| WO2013006055A8 (en) | 2013-08-15 |
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| PT2729167T (pt) | 2018-06-20 |
| US20160303214A1 (en) | 2016-10-20 |
| AU2012278407B2 (en) | 2017-01-19 |
| CN103687612B (zh) | 2017-12-15 |
| EP2729167B1 (en) | 2018-03-14 |
| HUE037969T2 (hu) | 2018-09-28 |
| CN103687612A (zh) | 2014-03-26 |
| LT2729167T (lt) | 2018-06-25 |
| DK2729167T3 (en) | 2018-04-30 |
| TR201808206T4 (tr) | 2018-07-23 |
| AU2012278407A1 (en) | 2014-01-16 |
| NZ618918A (en) | 2015-10-30 |
| JP2014520801A (ja) | 2014-08-25 |
| RU2607021C2 (ru) | 2017-01-10 |
| HRP20180890T1 (hr) | 2018-09-07 |
| CA2840096A1 (en) | 2013-01-10 |
| IL230326B (en) | 2018-03-29 |
| RS57267B1 (sr) | 2018-08-31 |
| US20140147469A1 (en) | 2014-05-29 |
| PL2729167T3 (pl) | 2018-08-31 |
| WO2013006055A1 (en) | 2013-01-10 |
| CA2840096C (en) | 2021-07-06 |
| RU2014104241A (ru) | 2015-08-20 |
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