JP6002757B2 - 抗菌性金属ナノ粒子の組成物および方法 - Google Patents
抗菌性金属ナノ粒子の組成物および方法 Download PDFInfo
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- JP6002757B2 JP6002757B2 JP2014512123A JP2014512123A JP6002757B2 JP 6002757 B2 JP6002757 B2 JP 6002757B2 JP 2014512123 A JP2014512123 A JP 2014512123A JP 2014512123 A JP2014512123 A JP 2014512123A JP 6002757 B2 JP6002757 B2 JP 6002757B2
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- FBWNMEQMRUMQSO-UHFFFAOYSA-N tergitol NP-9 Chemical compound CCCCCCCCCC1=CC=C(OCCOCCOCCOCCOCCOCCOCCOCCOCCO)C=C1 FBWNMEQMRUMQSO-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/16—Heavy metals; Compounds thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/16—Heavy metals; Compounds thereof
- A01N59/20—Copper
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
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- Agronomy & Crop Science (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Animal Behavior & Ethology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Toxicology (AREA)
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| US61/582,322 | 2011-12-31 | ||
| PCT/US2012/039462 WO2012162557A1 (en) | 2011-05-24 | 2012-05-24 | Compositions and methods for antimicrobial metal nanoparticles |
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| JP2014519504A JP2014519504A (ja) | 2014-08-14 |
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| EP (1) | EP2713747B1 (enExample) |
| JP (2) | JP6002757B2 (enExample) |
| AU (1) | AU2012258633A1 (enExample) |
| CA (1) | CA2835650C (enExample) |
| SG (1) | SG194862A1 (enExample) |
| WO (1) | WO2012162557A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101840948B1 (ko) | 2016-12-23 | 2018-05-04 | 영남대학교 산학협력단 | 나노 복합체, 이를 포함하는 코팅용 조성물, 나노 복합체의 제조 장치 및 방법 |
Families Citing this family (124)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140008210A1 (en) * | 2012-07-06 | 2014-01-09 | Aviva Biosciences Corporation | Methods and compositions for separating or enriching cells |
| US10016525B2 (en) | 2011-05-24 | 2018-07-10 | Agienic, Inc. | Antimicrobial compositions for use in wound care products |
| US9155310B2 (en) * | 2011-05-24 | 2015-10-13 | Agienic, Inc. | Antimicrobial compositions for use in products for petroleum extraction, personal care, wound care and other applications |
| US9849512B2 (en) | 2011-07-01 | 2017-12-26 | Attostat, Inc. | Method and apparatus for production of uniformly sized nanoparticles |
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| JP6407537B2 (ja) * | 2013-03-29 | 2018-10-17 | 株式会社Ｎｂｃメッシュテック | 殺菌・抗ウイルス性組成物 |
| EP3003030B1 (en) | 2013-05-30 | 2020-10-28 | Cupron, Inc. | Antimicrobial and antiviral polymeric materials |
| US10400339B2 (en) | 2013-09-23 | 2019-09-03 | Agienic, Inc. | Low water solubility compositions for use in corrosion protection |
| US9668890B2 (en) | 2013-11-22 | 2017-06-06 | Covidien Lp | Anti-thrombogenic medical devices and methods |
| EP3074024B1 (en) | 2013-11-25 | 2020-02-19 | Agienic Inc. | Antimicrobial compositions for use in products for petroleum extraction, personal care, wound care and other applications |
| DE102013114575A1 (de) * | 2013-12-19 | 2015-06-25 | AMiSTec GmbH & Co. KG | Verfahren zum Herstellen eines antimikrobiell wirksamen Verbundwerkstoffs und antimikrobiell wirksamer Verbundwerkstoff |
| ES2774035T3 (es) * | 2013-12-27 | 2020-07-16 | Bilix Co Ltd | Partículas de bilirrubina y su preparación para uso en terapia |
| US11039621B2 (en) | 2014-02-19 | 2021-06-22 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| US9622483B2 (en) | 2014-02-19 | 2017-04-18 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
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| WO2015168430A1 (en) | 2014-05-01 | 2015-11-05 | Agienic, Inc. | Compositions for use in corrosion protection |
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| US9919363B2 (en) * | 2014-09-23 | 2018-03-20 | Attostat, Inc. | System and method for making non-spherical nanoparticles and nanoparticle compositions made thereby |
| US9885001B2 (en) | 2014-09-23 | 2018-02-06 | Attostat, Inc. | Fuel additive composition and related methods |
| US9434006B2 (en) * | 2014-09-23 | 2016-09-06 | Attostat, Inc. | Composition containing spherical and coral-shaped nanoparticles and method of making same |
| US10190253B2 (en) | 2014-09-23 | 2019-01-29 | Attostat, Inc | Nanoparticle treated fabrics, fibers, filaments, and yarns and related methods |
| JP6700015B2 (ja) * | 2014-09-26 | 2020-05-27 | 株式会社Ｎｂｃメッシュテック | 抗真菌組成物 |
| BR112017010960A2 (pt) * | 2014-12-02 | 2018-02-14 | Dow Global Technologies Llc | micropartículas de poliuretano revestidas com um sal de zinco e métodos para preparação das mesmas |
| US9789228B2 (en) * | 2014-12-11 | 2017-10-17 | Covidien Lp | Antimicrobial coatings for medical devices and processes for preparing such coatings |
| EP3273907B1 (en) | 2015-03-30 | 2022-08-17 | C. R. Bard, Inc. | Application of antimicrobial agents to medical devices |
| US9839652B2 (en) | 2015-04-01 | 2017-12-12 | Attostat, Inc. | Nanoparticle compositions and methods for treating or preventing tissue infections and diseases |
| WO2016168346A1 (en) * | 2015-04-13 | 2016-10-20 | Attostat, Inc. | Anti-corrosion nanoparticle compositions |
| US11473202B2 (en) * | 2015-04-13 | 2022-10-18 | Attostat, Inc. | Anti-corrosion nanoparticle compositions |
| GB201507002D0 (en) * | 2015-04-24 | 2015-06-10 | Medical Res Council | Copper Oxo-hydroxide nanoparticles and their uses as biocidal agents |
| US10745570B2 (en) | 2015-05-18 | 2020-08-18 | Eastman Rodack Company | Copper-containing articles |
| US9963614B2 (en) | 2015-05-18 | 2018-05-08 | Eastman Kodak Company | Copper-containing articles and methods for providing same |
| WO2016186864A1 (en) | 2015-05-18 | 2016-11-24 | Eastman Kodak Company | Copper-containing polymeric compositions |
| US10918110B2 (en) * | 2015-07-08 | 2021-02-16 | Corning Incorporated | Antimicrobial phase-separating glass and glass ceramic articles and laminates |
| KR101763317B1 (ko) * | 2015-09-03 | 2017-08-02 | 한국생산기술연구원 | 발수 및 항균 기능을 동시에 구비하는 코어-쉘 구조의 나노입자 및 이를 이용한 코팅용 조성물 및 이들의 제조방법 |
| CN105123753A (zh) * | 2015-09-21 | 2015-12-09 | 山东农业大学 | 一种木质素原位还原的纳米氧化亚铜杀菌剂组合物 |
| US10064273B2 (en) | 2015-10-20 | 2018-08-28 | MR Label Company | Antimicrobial copper sheet overlays and related methods for making and using |
| JP6832058B2 (ja) * | 2015-11-04 | 2021-02-24 | 旭化成株式会社 | 抗菌性部材 |
| KR101809022B1 (ko) * | 2015-11-20 | 2017-12-15 | 한국해양과학기술원 | 다기능성 하이드로젤 입자 및 그 제조 방법 |
| US10201571B2 (en) | 2016-01-25 | 2019-02-12 | Attostat, Inc. | Nanoparticle compositions and methods for treating onychomychosis |
| WO2018013830A1 (en) * | 2016-07-14 | 2018-01-18 | Dong-Kyun Seo | Antimicrobial geopolymer compositions |
| AU2017298280B2 (en) | 2016-07-19 | 2021-09-02 | Behr Process Corporation | Antimicrobial paint composition and related methods |
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| JP6984122B2 (ja) * | 2016-12-15 | 2021-12-17 | 東洋製罐グループホールディングス株式会社 | 抗ウイルス性を有する分散液 |
| US10829382B2 (en) | 2017-01-20 | 2020-11-10 | Skysong Innovations | Aluminosilicate nanorods |
| JP6696957B2 (ja) * | 2017-05-23 | 2020-05-20 | 旭化成株式会社 | 抗菌抗カビ用塗料、及び該塗料を用いる抗菌抗カビ性部材の製造方法 |
| US11369109B2 (en) | 2020-06-11 | 2022-06-28 | Hrl Laboratories, Llc | Fast-acting antimicrobial surfaces, and methods of making and using the same |
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| JP7376355B2 (ja) * | 2017-09-04 | 2023-11-08 | 株式会社Ｎｂｃメッシュテック | 抗菌・抗ウイルス性組成物 |
| KR102091594B1 (ko) * | 2017-09-29 | 2020-03-20 | 충남대학교산학협력단 | 플라즈모닉 흡수체 및 이를 이용한 태양-수증기 생성 장치 |
| JP7217609B2 (ja) * | 2017-10-25 | 2023-02-03 | 株式会社Ｎｂｃメッシュテック | 抗ウイルス・殺菌消毒剤 |
| US20200323217A1 (en) * | 2017-11-01 | 2020-10-15 | Corning Incorporated | Antimicrobial floor coatings and formulations |
| US11646453B2 (en) | 2017-11-28 | 2023-05-09 | Attostat, Inc. | Nanoparticle compositions and methods for enhancing lead-acid batteries |
| US11018376B2 (en) | 2017-11-28 | 2021-05-25 | Attostat, Inc. | Nanoparticle compositions and methods for enhancing lead-acid batteries |
| EP3501336B1 (en) | 2017-12-20 | 2024-09-18 | The Gillette Company LLC | Oral care implement |
| EP3501335B1 (en) | 2017-12-20 | 2020-06-17 | The Gillette Company LLC | Oral care implement |
| EP3501334B1 (en) | 2017-12-20 | 2020-06-24 | The Gillette Company LLC | Oral care implement |
| EP3501333B1 (en) | 2017-12-20 | 2020-06-24 | The Gillette Company LLC | Oral care implement |
| US11400627B2 (en) | 2018-02-09 | 2022-08-02 | The Gillette Company Llc | Method for manufacturing an oral care implement |
| US11388985B2 (en) | 2018-02-09 | 2022-07-19 | The Gillette Company Llc | Connector for a manual oral care implement |
| EP3524093A1 (en) | 2018-02-09 | 2019-08-14 | The Gillette Company LLC | A method for manufacturing an oral care implement |
| EP3524091B1 (en) | 2018-02-09 | 2025-04-09 | The Gillette Company LLC | Manual oral care implement |
| PL3524092T3 (pl) | 2018-02-09 | 2025-11-24 | The Gillette Company Llc | Złącze dla manualnego przyrządu do higieny jamy ustnej |
| EP3817785A4 (en) | 2018-07-02 | 2022-07-20 | C. R. Bard, Inc. | ANTIMICROBIAL CATHETER ARRANGEMENTS AND METHODS THEREOF |
| US11659922B2 (en) | 2018-09-03 | 2023-05-30 | The Gillette Company, LLC. | Head for an oral-care implement and a kit comprising such head |
| PL3616561T3 (pl) | 2018-09-03 | 2022-11-21 | The Gillette Company Llc | Główka do narzędzia do higieny jamy ustnej i zestaw zawierający taką główkę |
| WO2020085270A1 (ja) * | 2018-10-23 | 2020-04-30 | 大阪ガスケミカル株式会社 | 抗菌剤組成物 |
| EP3643177A1 (de) | 2018-10-26 | 2020-04-29 | Amistec GmbH & Co. KG | Zinkmolybdad mit trikliner kristallstruktur als antimikrobieller wirkstoff |
| GB2579601A (en) * | 2018-12-05 | 2020-07-01 | Copper Clothing Ltd | Antimicrobial material |
| PL3714732T3 (pl) | 2019-03-29 | 2025-02-17 | The Gillette Company Llc | Główka dla przyrządu do higieny jamy ustnej oraz przyrząd do higieny jamy ustnej |
| WO2020252550A1 (pt) * | 2019-06-19 | 2020-12-24 | Universidade Estadual De Campinas | Composição para método de otimização na recuperação de petróleo em reservatório subterrâneo e método para otimização na recuperação de petróleo em reservatório subterrâneo |
| US12115250B2 (en) | 2019-07-12 | 2024-10-15 | Evoq Nano, Inc. | Use of nanoparticles for treating respiratory infections associated with cystic fibrosis |
| EP3818904B1 (en) | 2019-11-06 | 2024-12-18 | The Gillette Company LLC | Handle for an electrically operated personal care implement |
| EP3995282B1 (en) | 2020-11-06 | 2025-08-20 | The Gillette Company LLC | A method for manufacturing a handle for a personal care implement |
| EP3995042B1 (en) | 2020-11-06 | 2025-06-04 | The Gillette Company LLC | Handle for a personal care implement and personal care implement |
| EP3995041A1 (en) | 2020-11-06 | 2022-05-11 | The Gillette Company LLC | Polymeric handle material and use thereof |
| EP3854346B1 (en) | 2020-01-22 | 2022-09-21 | The Gillette Company LLC | Method for making a handle for an electrically operated personal care implement |
| EP3995039B1 (en) | 2020-11-06 | 2023-11-08 | The Gillette Company LLC | Handle for a personal care implement and personal care implement |
| EP3995037B1 (en) | 2020-11-06 | 2025-04-16 | The Gillette Company LLC | Handle for a personal care implement and personal care implement |
| WO2021158013A1 (en) * | 2020-02-04 | 2021-08-12 | Korea Atomic Energy Research Institute | Hydrogel and method for preparing the same |
| KR102146779B1 (ko) * | 2020-03-20 | 2020-08-24 | 유피씨(주) | 항균소취조성물과 이의 제조방법 및 이를 이용한 통기성 폴리에틸렌 합지원단으로 제조한 방호복 |
| KR102162521B1 (ko) * | 2020-04-20 | 2020-10-06 | 박건호 | 터치패널용 항균필름 |
| WO2021226362A1 (en) | 2020-05-08 | 2021-11-11 | Covalent Coating Technology, Inc. | Biocidal compositions of copper and silver and process for adhering to product substrates |
| US20230181760A1 (en) * | 2020-05-15 | 2023-06-15 | Rutgers, The State University Of New Jersey | Compositions and methods for treating wounds |
| US20210358260A1 (en) * | 2020-05-18 | 2021-11-18 | Synergy Blue, Llc | Casino gaming machines configured to resist viruses, bacteria and fungi and that are configured to curb the spread of infectious diseases |
| US20230260680A1 (en) * | 2020-07-01 | 2023-08-17 | The Regents Of The University Of Michigan | Copper-anf composite conductor fabrication |
| WO2022013803A1 (en) * | 2020-07-15 | 2022-01-20 | Sicora Technologies Private Limited | Anti-microbial composition comprising silane encapsulated cu-ag nanoparticles and process of preparation thereof |
| WO2022036466A1 (es) * | 2020-08-18 | 2022-02-24 | Universidad Mayor | Nano formulación para el tratamiento y/o prevención de heridas o úlceras infectadas o con colonización crítica, que incluye nanopartículas de cobre y péptidos derivados de colágeno |
| JP6888727B1 (ja) | 2020-08-31 | 2021-06-16 | 凸版印刷株式会社 | 化粧シート及び化粧材 |
| KR102263738B1 (ko) * | 2020-09-16 | 2021-06-10 | 주식회사 바이오시스템 | 항균 폴리염화비닐 패널 및 이의 제조 방법 |
| US20230413809A1 (en) * | 2020-11-05 | 2023-12-28 | Prerna Goradia | Disinfectant composition for surfaces and the preparation thereof |
| CN112521828A (zh) * | 2020-11-30 | 2021-03-19 | 中广健医疗科技有限公司 | 一种水下混凝土防污损涂覆料 |
| EP4262447A1 (en) * | 2020-12-15 | 2023-10-25 | JT International SA | Antimicrobial component for an aerosol generating system |
| WO2022149154A1 (en) * | 2021-01-05 | 2022-07-14 | Starshield Technologies Pvt. Ltd. | A copper nanoparticle composition and method of producing the same |
| US12456759B2 (en) | 2021-03-30 | 2025-10-28 | Evoq Nano, Inc. | Nanoparticle-enhanced lead-acid electrode paste and improved lead-acid batteries made therefrom |
| WO2022216652A1 (en) * | 2021-04-06 | 2022-10-13 | President And Fellows Of Harvard College | Structural colors with short-wavelength response for packaging applications |
| WO2022221748A1 (en) * | 2021-04-16 | 2022-10-20 | Board Of Regents, The University Of Texas System | Synthesis of antimicrobial pvp-coated bismuth nanoparticles |
| ES3037831T3 (en) * | 2021-04-19 | 2025-10-07 | Nanordica Medical Oue | Enhanced antimicrobial efficacy (synergy) of silver and copper compounds and medical use of their combinations |
| KR20240004515A (ko) | 2021-04-28 | 2024-01-11 | 코닝 인코포레이티드 | 고효율 Cu-계 항균 필름 및 기판 및 이를 제조하는 방법 |
| US11891538B1 (en) | 2021-08-25 | 2024-02-06 | Hrl Laboratories, Llc | Gradient-responsive corrosion-resistant coatings |
| JP7602233B2 (ja) * | 2021-11-12 | 2024-12-18 | 日本ペイントホールディングス株式会社 | 抗ウイルス性水性オーバーコート組成物および物品 |
| KR102820272B1 (ko) * | 2021-11-24 | 2025-06-13 | 충북대학교 산학협력단 | 필름 형성 소독제용 겔 조성물 |
| WO2023095923A1 (ja) | 2021-11-29 | 2023-06-01 | キヤノン株式会社 | コーティング組成物および物品 |
| WO2023220523A1 (en) | 2022-05-09 | 2023-11-16 | Carbon, Inc. | Method for direct coloration of resins for additive manufacturing |
| JP2023180157A (ja) * | 2022-06-08 | 2023-12-20 | 東洋製罐グループホールディングス株式会社 | 抗ウイルス性塗料組成物、塗膜、および、物品 |
| JP7417665B2 (ja) * | 2022-06-08 | 2024-01-18 | 東洋製罐グループホールディングス株式会社 | 抗ウイルス性エアゾール組成物、塗膜、および、物品 |
| USD1000774S1 (en) | 2022-06-24 | 2023-10-10 | Blakely Ventures, LLC | Shoe |
| USD1000795S1 (en) | 2022-06-24 | 2023-10-10 | Blakely Ventures, LLC | Shoe |
| USD1000773S1 (en) | 2022-06-24 | 2023-10-10 | Blakely Ventures, LLC | Shoe |
| USD982304S1 (en) | 2022-06-24 | 2023-04-04 | Blakely Ventures, LLC | Shoe last |
| USD1087568S1 (en) | 2022-10-14 | 2025-08-12 | Blakely Ventures, LLC | Shoe |
| USD1088432S1 (en) | 2022-10-14 | 2025-08-19 | Blakely Ventures, LLC | Shoe |
| USD1087569S1 (en) | 2022-10-14 | 2025-08-12 | Blakely Ventures, LLC | Shoe |
| USD1087570S1 (en) | 2022-10-14 | 2025-08-12 | Blakely Ventures, LLC | Shoe |
| USD1088451S1 (en) | 2022-10-14 | 2025-08-19 | Blakely Ventures, LLC | Shoe |
| USD1087551S1 (en) | 2022-10-14 | 2025-08-12 | Blakely Ventures, LLC | Shoe |
| US20240336755A1 (en) * | 2023-04-10 | 2024-10-10 | Evoq Nano, Inc. | Polymer compositions with antimicrobial nanoparticles and methods of manufacture |
| US12063933B1 (en) | 2023-07-20 | 2024-08-20 | Corning Incorporated | Antimicrobial compositions including copper(I) salts and additives |
| IT202300021111A1 (it) | 2023-10-11 | 2025-04-11 | Cartiere Carrara S P A | Prodotto tissutale antivirale e antibatterico e metodo per la sua fabbricazione |
| ES3036669A1 (es) * | 2024-03-20 | 2025-09-23 | Consejo Superior Investigacion | Material catalítico para la inactivación de patógenos |
| CN118750469B (zh) * | 2024-06-12 | 2025-09-26 | 华中农业大学 | 一种尺寸可控的噬菌体水凝胶微球及其制备方法 |
| JP7716138B1 (ja) * | 2024-07-30 | 2025-07-31 | 株式会社コスモ技研 | 無機系コート液、無機系コート膜および無機系コート膜を有する器具 |
Family Cites Families (156)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2739922A (en) | 1952-03-13 | 1956-03-27 | Herman A Shelanski | Mixtures of polymeric n-vinyl pyrrolidone and halogens |
| US2900305A (en) | 1952-04-15 | 1959-08-18 | Gen Aniline & Film Corp | Preparation of iodine polyvinylpyrrolidone adducts |
| BE615889A (enExample) | 1952-04-15 | 1900-01-01 | ||
| US7291570B1 (en) | 2000-06-02 | 2007-11-06 | Milliken & Company | Yarns and fabrics having a wash-durable non-electrically conductive topically applied metal-based finish |
| US3773465A (en) | 1970-10-28 | 1973-11-20 | Halliburton Co | Inhibited treating acid |
| DE2942179A1 (de) | 1979-10-18 | 1981-05-07 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von pvp-iod |
| US4533435A (en) | 1984-06-07 | 1985-08-06 | Microban Products Company | Antimicrobial paper |
| GB8616294D0 (en) | 1986-07-03 | 1986-08-13 | Johnson Matthey Plc | Antimicrobial compositions |
| US4745006A (en) | 1986-12-29 | 1988-05-17 | Allied Corporation | Method for coating nylon-6 for improved thermal stability |
| JPH03213509A (ja) * | 1990-01-16 | 1991-09-18 | Kanebo Ltd | 抗菌性繊維の製造方法 |
| US5180585A (en) * | 1991-08-09 | 1993-01-19 | E. I. Du Pont De Nemours And Company | Antimicrobial compositions, process for preparing the same and use |
| US5344636A (en) * | 1991-11-27 | 1994-09-06 | Kabushiki Kaisha Kaisui Kagaku Kenkyujo | Anti-microorganism agent and anti-microorganism resin or rubber composition |
| JPH07118925A (ja) * | 1993-10-21 | 1995-05-09 | Toray Ind Inc | 牽切紡用抗菌性ポリアミドトウ及びその製造方法 |
| EP0727427A4 (en) * | 1993-11-05 | 1997-10-15 | Meiji Milk Prod Co Ltd | ANTIBACTERIAL, ANTI-FUNGI AND ANTIVIRES |
| US6283308B1 (en) | 1998-06-17 | 2001-09-04 | Microban Products Company | Bacteriostatic filter cartridge |
| US6854601B2 (en) | 1995-12-15 | 2005-02-15 | Microban Products Company | Bacteriostatic filter cartridge |
| US6171496B1 (en) | 1995-12-15 | 2001-01-09 | Microban Products Company | Antimicrobial filter cartridge |
| US6540916B2 (en) | 1995-12-15 | 2003-04-01 | Microban Products Company | Antimicrobial sintered porous plastic filter |
| US6332293B1 (en) | 1997-02-28 | 2001-12-25 | Milliken & Company | Floor mat having antimicrobial characteristics |
| DE69835671T2 (de) | 1997-05-12 | 2007-08-23 | Microban Products Co. | Antimikrobielle bürste |
| US5929136A (en) * | 1997-06-13 | 1999-07-27 | Xerox Corporation | Coated carriers |
| AU9542298A (en) | 1997-10-03 | 1999-04-27 | Herberts G.M.B.H. | Biocidal Power Coating Composition, Its Preparation And Use |
| US6432416B1 (en) | 1997-10-03 | 2002-08-13 | Dupont Powder Coatings Usa, Inc. | Anti-microbial power coating |
| US6605751B1 (en) * | 1997-11-14 | 2003-08-12 | Acrymed | Silver-containing compositions, devices and methods for making |
| US5919554A (en) | 1998-01-30 | 1999-07-06 | Microban Products Company | Antimicrobial fiberglass reinforced plastic composite |
| US5968207A (en) | 1998-02-20 | 1999-10-19 | Milliken & Company | Esterified triclosan derivatives as improved textile antimicrobial agents |
| US7354596B1 (en) | 1998-05-01 | 2008-04-08 | 3M Innovative Properties Company | Anti-microbial agent delivery system |
| DE69929697T2 (de) | 1998-06-29 | 2006-10-19 | Microban Products Co. | Anti-mikrobielle semipermeable membran |
| US6238575B1 (en) | 1998-07-29 | 2001-05-29 | Microban Products Company | Antimicrobial treatment of enclosed systems having continuous or intermittent fluid flow |
| EP1161466A4 (en) | 1998-09-08 | 2002-04-10 | Microban Products | ANTIMICROBIAL ACRYLIC MATERIAL |
| US6248342B1 (en) | 1998-09-29 | 2001-06-19 | Agion Technologies, Llc | Antibiotic high-pressure laminates |
| US6436422B1 (en) | 1998-11-23 | 2002-08-20 | Agion Technologies L.L.C. | Antibiotic hydrophilic polymer coating |
| US6296863B1 (en) | 1998-11-23 | 2001-10-02 | Agion Technologies, Llc | Antimicrobial fabric and medical graft of the fabric |
| US6365130B1 (en) | 1998-11-23 | 2002-04-02 | Agion Technologies L.L.C. | Antimicrobial chewing gum |
| US6585767B1 (en) | 1998-11-23 | 2003-07-01 | Agion Technologies, Inc. | Antimicrobial suturing ring for heart valve |
| US6187456B1 (en) | 1999-04-09 | 2001-02-13 | Milliken & Company | Method of inhibiting color change in a plastic article comprising silver-based antimicrobials |
| US6582715B1 (en) | 1999-04-27 | 2003-06-24 | Agion Technologies, Inc. | Antimicrobial orthopedic implants |
| US6482756B2 (en) | 1999-07-27 | 2002-11-19 | Milliken & Company | Method of retaining antimicrobial properties on a halamine-treated textile substrate while simultaneously reducing deleterious odor and skin irritation effects |
| US6267590B1 (en) | 1999-11-24 | 2001-07-31 | Agion Technologies, Llc | Antimicrobial dental products |
| AU1956401A (en) | 1999-12-10 | 2001-06-18 | Microban Products Company | Antimicrobial synthetic ion exchange resins |
| US6716895B1 (en) | 1999-12-15 | 2004-04-06 | C.R. Bard, Inc. | Polymer compositions containing colloids of silver salts |
| US20020160144A1 (en) | 2001-02-20 | 2002-10-31 | Higgins Kenneth B. | Adhesive-free carpet tiles and methods of installing adhesive-free carpet tiles |
| IL135487A (en) | 2000-04-05 | 2005-07-25 | Cupron Corp | Antimicrobial and antiviral polymeric materials and a process for preparing the same |
| US6461386B1 (en) | 2000-05-17 | 2002-10-08 | Milliken & Company | Antimicrobial transfer substrates and methods of use therewith |
| US6946433B2 (en) | 2000-06-02 | 2005-09-20 | Milliken & Company | Textiles having a wash-durable silver-ion based antimicrobial topical treatment |
| US20030170314A1 (en) * | 2000-07-27 | 2003-09-11 | Burrell Robert E. | Compositions of metal-containing compounds |
| US6866859B2 (en) | 2000-08-30 | 2005-03-15 | Biocoat Incorporated | Bi-laminar, hyaluronan coatings with silver-based anti-microbial properties |
| ES2325057T3 (es) | 2000-08-31 | 2009-08-25 | Jagotec Ag | Particulas molturadas. |
| US6342212B1 (en) | 2000-09-01 | 2002-01-29 | Milliken & Company | Antimicrobial adhesive latexes and methods of making thereof |
| US6544621B1 (en) | 2000-09-01 | 2003-04-08 | Milliken & Company | Floor covering articles comprising antimicrobial adhesive latex components |
| US6479144B2 (en) | 2000-12-04 | 2002-11-12 | Milliken & Company | Anti-tack spandex fibers containing antimicrobial agents therein and fabrics made therefrom |
| US7080412B2 (en) | 2000-12-15 | 2006-07-25 | Milliken & Company | Insect barrier garment |
| US7087255B2 (en) | 2000-12-27 | 2006-08-08 | Wm. Wrigley Jr. Company | Chewing gums that provide breath freshening characteristics |
| US20020124323A1 (en) | 2001-01-09 | 2002-09-12 | Cliver James D. | Process for patterning textile materials and fabrics made therefrom |
| CA2433059C (en) * | 2001-01-30 | 2009-05-12 | The Procter & Gamble Company | Coating compositions for modifying surfaces |
| US6844026B2 (en) * | 2001-02-12 | 2005-01-18 | Rhodia Chimie | Preparation of particles by hydrolysis of a metal cation in the presence of a polymer |
| US6448306B1 (en) | 2001-03-23 | 2002-09-10 | Milliken & Company | Antimicrobial articles made from nitrile or natural rubber |
| US6555599B2 (en) | 2001-03-26 | 2003-04-29 | Milliken & Company | Antimicrobial vulcanized EPDM rubber articles |
| US6455610B1 (en) | 2001-03-23 | 2002-09-24 | Milliken & Company | Antimicrobial pre-vulcanized rubber compositions |
| US6852776B2 (en) | 2001-07-10 | 2005-02-08 | Microban Products Company | Antimicrobial concentrates containing non-yellowing agents |
| US6979455B2 (en) | 2001-07-10 | 2005-12-27 | Microban Products Company | Antimicrobial concentrates |
| MXPA03012038A (es) | 2001-07-25 | 2004-06-03 | Microban Products | Resina de melamina antimicrobiana y productos hechos de la misma. |
| US20030095230A1 (en) | 2001-08-02 | 2003-05-22 | Neely Frank L. | Antimicrobial lenses and methods of their use related patent applications |
| DE60239140D1 (de) | 2001-10-10 | 2011-03-24 | Microban Products Co | Antimikrobielle strahlungshärtbare beschichtung |
| US6641842B2 (en) | 2001-12-12 | 2003-11-04 | Milliken & Company | Thermoplastic articles exhibiting high surface-available silver |
| US7381715B2 (en) | 2001-12-21 | 2008-06-03 | E.I. Du Pont De Nemours And Company | Antimicrobial solid surface materials containing chitosan-metal complexes |
| US6797278B2 (en) | 2001-12-21 | 2004-09-28 | Milliken & Company | Antimicrobial sol-gel films comprising specific metal-containing antimicrobial agents |
| US7357949B2 (en) | 2001-12-21 | 2008-04-15 | Agion Technologies Inc. | Encapsulated inorganic antimicrobial additive for controlled release |
| US7296690B2 (en) | 2002-04-18 | 2007-11-20 | The Cupron Corporation | Method and device for inactivating viruses |
| US7951853B2 (en) | 2002-05-02 | 2011-05-31 | Smart Anti-Microbial Solutions, Llc | Polymer-based antimicrobial agents, methods of making said agents, and products incorporating said agents |
| MXPA04012297A (es) | 2002-06-07 | 2005-04-08 | Microban Products | Carton de yeso antimicrobiano. |
| CN1671356A (zh) | 2002-07-23 | 2005-09-21 | 密克罗伴产品公司 | 抗微生物蜜胺树脂和由其制备的产品 |
| US20060014810A1 (en) | 2002-07-26 | 2006-01-19 | Microban Products Company | Durable antimicrobial leather |
| DK1532201T3 (da) | 2002-08-29 | 2007-05-29 | Microban Products | Antimicrobial acrylic polymer |
| US6641829B1 (en) | 2002-10-22 | 2003-11-04 | Milliken & Company | Topical application of solid antimicrobials to carpet pile fibers during carpet manufacture |
| JP4387097B2 (ja) * | 2002-11-29 | 2009-12-16 | 株式会社シナネンゼオミック | コンクリート用抗菌剤、コンクリート組成物及びコンクリート製品 |
| KR100656169B1 (ko) | 2002-12-23 | 2006-12-12 | 삼성전자주식회사 | 나노 사이즈의 금속 입자를 이용하여 물체의 표면에항균성을 부여하는 방법 |
| US6946119B2 (en) | 2003-02-14 | 2005-09-20 | J.M. Huber Corporation | Precipitated silica product with low surface area, dentifrices containing same, and processes |
| US6921546B2 (en) | 2003-02-20 | 2005-07-26 | Gemtron Corporation | Antimicrobial glass and glass-like products and method of preparing same |
| US7132378B2 (en) | 2003-04-23 | 2006-11-07 | Milliken & Company | Fabrics having a topically applied silver-based finish with a cross-linked binder system for improved high-temperature wash durability |
| US6943205B2 (en) | 2003-04-25 | 2005-09-13 | Milliken & Company | Antimicrobial articles and compositions made from styrene butadiene rubber |
| US6846871B2 (en) | 2003-04-25 | 2005-01-25 | Milliken & Company | Antimicrobial resin cured rubber articles and prevulcanized compositions |
| US6852782B2 (en) | 2003-04-25 | 2005-02-08 | Milliken & Company | Antimicrobial articles and compositions made from non-silicone vulcanized rubber |
| US20040253435A1 (en) | 2003-06-11 | 2004-12-16 | Ishizuka Garasu Kabushiki Kaisha | Antibacterial molded resin |
| MXPA05013850A (es) * | 2003-06-17 | 2006-05-17 | Phibro Tech Inc | Conservador particulado para madera y metodo para producir el mismo. |
| US20060018966A1 (en) * | 2003-07-22 | 2006-01-26 | Lin Victor S | Antimicrobial mesoporous silica nanoparticles |
| US20050028563A1 (en) | 2003-08-08 | 2005-02-10 | Milliken & Company | Garment for use with sensitive skin, and method and fabric for us in making same |
| US20050147657A1 (en) | 2003-08-14 | 2005-07-07 | Milliken & Company | White silver-containing wound care device |
| WO2005021626A2 (en) | 2003-08-28 | 2005-03-10 | Microban Products Company | Antimicrobial acrylic polymer |
| DE10340277B4 (de) | 2003-08-29 | 2006-11-23 | Bio-Gate Bioinnovative Materials Gmbh | Körperpflegemittel mit Silber-Agglomeraten |
| US20070196607A1 (en) | 2003-09-09 | 2007-08-23 | Ong Ivan W | Antimicrobial hose |
| EP1685077B1 (en) | 2003-11-17 | 2013-06-05 | Microban Products Company | Method of making cementitious slab products having antimicrobial properties |
| WO2005053616A2 (en) | 2003-12-01 | 2005-06-16 | Microban Products Company | Antimicrobial composition |
| WO2005058238A2 (en) | 2003-12-12 | 2005-06-30 | Microban Products Company | Antimicrobial composition |
| WO2005069962A2 (en) | 2004-01-21 | 2005-08-04 | Microban Products Company | Antimicrobial ceramic glaze |
| US20050196430A1 (en) | 2004-01-21 | 2005-09-08 | Microban Products Company | Antimicrobial enamel glaze |
| WO2005079738A1 (en) | 2004-02-18 | 2005-09-01 | Marianna Cooley | Antimicrobial formulations and methods of using the same |
| US7517819B2 (en) | 2004-02-18 | 2009-04-14 | Milliken & Company | Dual function fabrics and method of making same |
| US7135449B2 (en) | 2004-02-20 | 2006-11-14 | Milliken & Company | Composition for removal of odors and contaminants from textiles and method |
| US20050258093A1 (en) | 2004-05-24 | 2005-11-24 | Microban Products Company | Antimicrobial activated carbon and method of making |
| US7595355B2 (en) | 2004-06-24 | 2009-09-29 | Agion Technologies, Inc. | Antimicrobial coating for erosive environments |
| US7645824B2 (en) | 2004-06-24 | 2010-01-12 | Agion Technologies, Inc | Color stable antimicrobial coatings |
| GB0414333D0 (en) | 2004-06-25 | 2004-07-28 | Dupont Teijin Films Us Ltd | Polymeric film |
| EP1763536B1 (en) | 2004-07-02 | 2010-09-08 | Pioneer-Hi-Bred International, Inc. | Antifungal polypeptides |
| US8361553B2 (en) | 2004-07-30 | 2013-01-29 | Kimberly-Clark Worldwide, Inc. | Methods and compositions for metal nanoparticle treated surfaces |
| CN101010004B (zh) * | 2004-07-30 | 2012-10-03 | 金伯利-克拉克环球有限公司 | 抗微生物的装置和组合物 |
| CA2575967A1 (en) | 2004-08-04 | 2006-09-14 | Novacentrix Corp. | Carbon and metal nanomaterial composition and synthesis |
| WO2006024253A1 (de) * | 2004-09-03 | 2006-03-09 | Weinmann Geräte für Medizin GmbH & Co. KG | Kunststoffe für medizintechnische geräte |
| EP3150675A1 (en) | 2004-09-03 | 2017-04-05 | Microban Products Company | Antimicrobial cementitious compositions |
| US9289378B2 (en) | 2004-09-20 | 2016-03-22 | Avent, Inc. | Antimicrobial amorphous compositions |
| US20060068024A1 (en) * | 2004-09-27 | 2006-03-30 | Schroeder Kurt M | Antimicrobial silver halide composition |
| JP5275629B2 (ja) | 2004-11-07 | 2013-08-28 | カプロン インコーポレイテッド | 創傷、火傷及び他の皮膚症状の治療用銅含有材料 |
| WO2006051529A1 (en) | 2004-11-09 | 2006-05-18 | The Cupron Corporation | Methods and materials for skin care |
| EP1830812A2 (en) | 2004-12-06 | 2007-09-12 | Nanotechnologies, Inc. | Anti-viral uses of metal nanomaterial compositions |
| US20080017307A1 (en) | 2005-01-21 | 2008-01-24 | Microban Products Company | Antimicrobial overlay sheet and method |
| US20060166024A1 (en) | 2005-01-21 | 2006-07-27 | Microban Products Company | Antimicrobial melamine resin and products |
| AU2006216655B2 (en) | 2005-02-23 | 2012-05-31 | Zimmer Technology, Inc. | Blend hydrogels and methods of making |
| MX2007011572A (es) | 2005-03-21 | 2007-12-06 | Cupron Corp | Lote maestro polimerico antimicrobiano y antiviral, procedimientos para producir el material polimerico a partir de estos y productos producidos a partir de estos. |
| WO2006102367A1 (en) | 2005-03-22 | 2006-09-28 | Biosafe Inc. | Method of creating a solvent-free polymeric silicon-containing quaternary ammonium antimicrobial agent having superior sustained antimicrobial properties |
| US7507281B2 (en) | 2005-09-02 | 2009-03-24 | Microban Products Company | Antimicrobial cementitious composition, method and article |
| US20070072753A1 (en) | 2005-09-26 | 2007-03-29 | Microban Products Company | Antimicrobial fitness article |
| US20070110781A1 (en) | 2005-11-14 | 2007-05-17 | Microban Products Company | Antimicrobial article for use in medical environment |
| US20070195260A1 (en) | 2006-02-22 | 2007-08-23 | Microban Products Company | Antimicrobial spectacle |
| US20070195259A1 (en) | 2006-02-22 | 2007-08-23 | Microban Products Company | Antimicrobial spectacle |
| US20070199890A1 (en) | 2006-02-27 | 2007-08-30 | Agion Technologies, Inc. | Antimicrobial activated carbon and use thereof |
| JP2009528099A (ja) | 2006-03-03 | 2009-08-06 | コロプラスト アクティーゼルスカブ | 抗炎症性鎮痛剤並びに銀イオン及び元素周期表の第ｉｖ族の遷移元素の複合体を含む創傷包帯 |
| US20070243263A1 (en) | 2006-04-14 | 2007-10-18 | Agion Technologies, Inc. | Antiviral Methods |
| US7691400B2 (en) * | 2006-05-05 | 2010-04-06 | Medtronic Vascular, Inc. | Medical device having coating with zeolite drug reservoirs |
| US20070292486A1 (en) | 2006-06-15 | 2007-12-20 | The Penn State Research Foundation | Novel polymer-nano/microparticle composites |
| US20080182125A1 (en) | 2006-08-24 | 2008-07-31 | Microban Products Company | Cationic latex as a carrier for bioactive ingredients and its use in wallboard manufacture |
| US8518449B2 (en) | 2006-08-25 | 2013-08-27 | Sciessent Llc | Polymer particle coating method |
| US20080057134A1 (en) | 2006-08-31 | 2008-03-06 | Agion Technologies, Inc. | Antifungal compositions and method |
| US20080102122A1 (en) * | 2006-10-31 | 2008-05-01 | Shivkumar Mahadevan | Antimicrobial polymeric articles, processes to prepare them and methods of their use |
| US20080147019A1 (en) * | 2006-12-19 | 2008-06-19 | Kimberly-Clark Worldwide, Inc. | Antimicrobial component system containing metallic nanoparticles and chitosan and/or its derivatives |
| US7858674B2 (en) | 2007-02-05 | 2010-12-28 | Milliken & Co. | Antimicrobial rubber formulations and molded article |
| US7426776B2 (en) | 2007-02-07 | 2008-09-23 | Milliken & Company | Nonwoven towel with microsponges |
| AU2007346702A1 (en) | 2007-02-09 | 2008-08-14 | Microban Products Company | Antimicrobial currency, material and method |
| US20090104459A1 (en) | 2007-02-20 | 2009-04-23 | Microban Products Company | Ceramic glaze having antimicrobial property |
| US7858539B2 (en) | 2007-04-09 | 2010-12-28 | Milliken & Company | Processes for generating halamine compounds on textile substrates to produce antimicrobial finish |
| US20100291374A1 (en) | 2007-06-12 | 2010-11-18 | Ajjer Llc | Composites Comprising Nanoparticles |
| US9211510B2 (en) | 2007-07-06 | 2015-12-15 | M. Technique Co., Ltd. | Method for producing nanoparticles by forced ultrathin film rotary processing |
| US20090092538A1 (en) | 2007-10-08 | 2009-04-09 | Amit Khanolkar | Methods for forming stabilized metal salt particles |
| EP2223102A4 (en) | 2007-11-21 | 2016-09-28 | Microban Products | IN-SITU INDICATOR DETECTION AND QUANTIFICATION FOR CORRELATION WITH ONE ADDITIONAL |
| WO2009120784A2 (en) | 2008-03-25 | 2009-10-01 | Pavco Inc. | Electrodeposited metallic finishes including antimicrobial agents |
| GB0810719D0 (en) | 2008-06-11 | 2008-07-16 | Dupont Teijin Films Us Ltd | Polymeric film |
| RU2542488C2 (ru) | 2008-09-03 | 2015-02-20 | ЭнБиСи МЕШТЕК, ИНК. | Противовирусное средство |
| KR101675585B1 (ko) | 2008-12-26 | 2016-11-11 | 가부시키가이샤 엔비씨 메슈테크 | 항바이러스성을 지닌 부재 |
| US20100227052A1 (en) * | 2009-03-09 | 2010-09-09 | Baxter International Inc. | Methods for processing substrates having an antimicrobial coating |
| EP2424371A1 (en) * | 2009-04-28 | 2012-03-07 | Harman Technology Limited | Biocidal composition |
| WO2010127335A2 (en) | 2009-05-01 | 2010-11-04 | Xmicroban Products Company | Antimicrobial zinc pyrithione composition and method |
| JP5523777B2 (ja) * | 2009-09-09 | 2014-06-18 | 株式会社Ｎｂｃメッシュテック | 水生生物付着防止用部材及びその製造方法 |
| RU2429820C2 (ru) * | 2009-09-24 | 2011-09-27 | Закрытое акционерное общество "Институт прикладной нанотехнологии" (ЗАО"ИПН") | Антисептическая мазь наружного применения (2 варианта) |
| IN2012DN02357A (enExample) | 2009-09-30 | 2015-08-21 | Nbc Meshtec Inc | |
| CN102040828A (zh) | 2009-10-26 | 2011-05-04 | 杜邦兴达（无锡）单丝有限公司 | 抗菌组合物、抗菌刷丝及它们的制备方法 |
| US20110100630A1 (en) | 2009-11-02 | 2011-05-05 | Baker Hughes Incorporated | Method of Mitigating Corrosion Rate of Oilfield Tubular Goods |
| US20120321686A1 (en) * | 2009-12-24 | 2012-12-20 | Eth Zurich | Antifungal Material |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101840948B1 (ko) | 2016-12-23 | 2018-05-04 | 영남대학교 산학협력단 | 나노 복합체, 이를 포함하는 코팅용 조성물, 나노 복합체의 제조 장치 및 방법 |
| WO2018117742A1 (ko) * | 2016-12-23 | 2018-06-28 | 영남대학교 산학협력단 | 나노 복합체, 이를 포함하는 코팅용 조성물, 나노 복합체의 제조 장치 및 방법 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2017019837A (ja) | 2017-01-26 |
| US20120301533A1 (en) | 2012-11-29 |
| US8563020B2 (en) | 2013-10-22 |
| WO2012162557A1 (en) | 2012-11-29 |
| CA2835650A1 (en) | 2012-11-29 |
| JP6423833B2 (ja) | 2018-11-14 |
| US20120301531A1 (en) | 2012-11-29 |
| US9226508B2 (en) | 2016-01-05 |
| JP2014519504A (ja) | 2014-08-14 |
| EP2713747A1 (en) | 2014-04-09 |
| AU2012258633A1 (en) | 2013-11-28 |
| US20120301530A1 (en) | 2012-11-29 |
| EP2713747A4 (en) | 2014-11-19 |
| CA2835650C (en) | 2018-05-29 |
| US20130171225A1 (en) | 2013-07-04 |
| EP2713747B1 (en) | 2023-02-22 |
| SG194862A1 (en) | 2013-12-30 |
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