JP5979816B2 - 不飽和脂肪酸及び酸化窒素放出化合物を含む組成物、並びに認知機能及び関連の機能を高めるためのそれらの使用 - Google Patents

不飽和脂肪酸及び酸化窒素放出化合物を含む組成物、並びに認知機能及び関連の機能を高めるためのそれらの使用 Download PDF

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JP5979816B2
JP5979816B2 JP2010541427A JP2010541427A JP5979816B2 JP 5979816 B2 JP5979816 B2 JP 5979816B2 JP 2010541427 A JP2010541427 A JP 2010541427A JP 2010541427 A JP2010541427 A JP 2010541427A JP 5979816 B2 JP5979816 B2 JP 5979816B2
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JP2011508773A (ja
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ユアロン パン，
ユアロン パン，
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Nestec SA
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  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
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  • Natural Medicines & Medicinal Plants (AREA)
  • Biotechnology (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • Botany (AREA)
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JP2010541427A 2008-01-04 2008-12-19 不飽和脂肪酸及び酸化窒素放出化合物を含む組成物、並びに認知機能及び関連の機能を高めるためのそれらの使用 Active JP5979816B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1009708P 2008-01-04 2008-01-04
US61/010,097 2008-01-04
US13738208P 2008-07-30 2008-07-30
US61/137,382 2008-07-30
PCT/US2008/013870 WO2009088433A1 (en) 2008-01-04 2008-12-19 Compositions comprising unsaturated fatty acids and nitric oxide releasing compounds and use thereof for enhancing congnitive and related functions

Publications (3)

Publication Number Publication Date
JP2011508773A JP2011508773A (ja) 2011-03-17
JP2011508773A5 JP2011508773A5 (enExample) 2012-02-09
JP5979816B2 true JP5979816B2 (ja) 2016-08-31

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JP2010541427A Active JP5979816B2 (ja) 2008-01-04 2008-12-19 不飽和脂肪酸及び酸化窒素放出化合物を含む組成物、並びに認知機能及び関連の機能を高めるためのそれらの使用

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US (4) US20100233304A1 (enExample)
EP (2) EP2224930B1 (enExample)
JP (1) JP5979816B2 (enExample)
CN (2) CN101909632A (enExample)
AU (1) AU2008347177B2 (enExample)
BR (1) BRPI0822238B8 (enExample)
CA (2) CA2994586C (enExample)
ES (2) ES2773928T5 (enExample)
MX (1) MX337760B (enExample)
RU (1) RU2500402C2 (enExample)
WO (1) WO2009088433A1 (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8252742B2 (en) * 2004-12-30 2012-08-28 Hill's Pet Nutrition, Inc. Methods for enhancing the quality of life of a senior animal
JP5274248B2 (ja) 2005-05-27 2013-08-28 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 酸化窒素治療及び医生物的応用のための酸化窒素放出粒子
AU2008307494B2 (en) * 2007-10-04 2013-09-05 Société des Produits Nestlé S.A. Compositions and methods for enhancing cognitive function
AU2013200758B2 (en) * 2008-07-18 2014-06-12 Hill's Pet Nutrition, Inc. Methods for enhancing the quality of life of a senior animal
JP2011528556A (ja) * 2008-07-18 2011-11-24 ヒルズ・ペット・ニュートリシャン・インコーポレーテッド 高齢の動物の生活の質を向上させるための方法
ES2958410T3 (es) 2009-08-21 2024-02-08 Novan Inc Geles tópicos
DK2467173T3 (da) 2009-08-21 2019-07-29 Novan Inc Sårbandager, fremgangsmåder til anvendelse heraf og fremgangsmåder til dannelse deraf
ES2593880T3 (es) * 2009-09-11 2016-12-13 Nestec, S.A. Composiciones y métodos para mejorar las funciones cognitivas y relacionadas en animales
US20130129860A1 (en) * 2009-12-29 2013-05-23 Nestec S.A. Nutritional compositions comprising fruit flakes containing docosahexaenoic acid
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
CN102552457A (zh) * 2010-12-24 2012-07-11 漆又毛 一种氨基酸和提取物组合物的药物用途
CN103442725A (zh) * 2011-01-25 2013-12-11 雀巢产品技术援助有限公司 治疗、减轻或预防动物的视觉系统衰退的方法和组合物
MX2013009544A (es) * 2011-02-18 2013-09-26 Nestec Sa Metodos y composiciones para tratar, reducir o prevenir daño al sistema nervioso de animales.
WO2012118819A2 (en) 2011-02-28 2012-09-07 Novan, Inc. Nitric oxide-releasing s-nitrosothiol-modified silica particles and methods of making the same
ES2727043T3 (es) * 2011-03-18 2019-10-11 Nestle Sa Composiciones y métodos útiles para mejorar enfermedades relacionadas con la edad
AT511776B1 (de) * 2011-07-26 2014-03-15 Gonadosan Gmbh Verwendung von citrullin und ein kombinationspräparat zur verbesserung der männlichen fertilität
US20130059028A1 (en) * 2011-09-01 2013-03-07 Julie Marie Foy Compositions and Methods for Providing a Life-Stage-Appropriate Animal Diet
CN102600124B (zh) * 2012-02-06 2014-03-26 单宝华 Omega-3增强组合物及其应用
CA2888791C (en) * 2012-10-30 2021-07-27 Kyowa Hakko Bio Co., Ltd. Use of a combination of citrulline and glutathione in the treatment of brain damage and cognitive decline
US9265458B2 (en) 2012-12-04 2016-02-23 Sync-Think, Inc. Application of smooth pursuit cognitive testing paradigms to clinical drug development
US9380976B2 (en) 2013-03-11 2016-07-05 Sync-Think, Inc. Optical neuroinformatics
CN103609752B (zh) * 2013-12-02 2016-05-25 内蒙古伊利实业集团股份有限公司 一种改善脑部认知功能的组合物及其制备方法与应用
US20160341708A1 (en) * 2013-12-19 2016-11-24 Hill's Pet Nutrition, Inc. Method for determining spoilage of high protein foods
WO2015160234A1 (en) * 2014-04-17 2015-10-22 N.V. Nutricia Composition for brain improvement
EP3203857A1 (en) * 2014-10-10 2017-08-16 Nestec S.A. Compositions and methods for enhancing mobility or activity or treating frailty
MA40847A (fr) * 2014-10-22 2017-09-13 Raffaele Migliaccio Association comprenant de la spiruline et du palmitoyléthanolamide et/ou des sels ou des dérivés pharmaceutiquement acceptables de ceux-ci et leurs formulations, pour une utilisation dans la prévention et/ou le traitement d'états d'hyperactivité des tissus
AU2015372576B2 (en) * 2014-12-29 2018-09-06 Hill's Pet Nutrition, Inc. Food composition and method of use
ES2860427T3 (es) * 2015-06-22 2021-10-05 Nestle Sa Composiciones y métodos para mejorar la neurogénesis en animales
CN105602998A (zh) * 2016-01-18 2016-05-25 青岛哈拿生物科技有限公司 一种水溶性天然一氧化氮的制作方法及应用
JP2019518744A (ja) * 2016-05-27 2019-07-04 ネステク ソシエテ アノニム 運動障害を治療又は予防するための栄養組成物
EP3518919A1 (en) * 2016-09-29 2019-08-07 Société des Produits Nestlé S.A. Omega 3 fatty acids and choline as neuroprotectant in patients with no dementia
JOP20190146A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض الكبد
EP3595646A4 (en) * 2017-03-18 2021-01-13 McGarrah, Steven, M. PET FOOD WITH CANNABIDIOLIC ACID
JP7270546B2 (ja) * 2017-04-11 2023-05-10 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 個体における認知的加齢を特定及び軽減するためのオメガ３脂肪酸及びビタミンｄレベル
MA49906A (fr) 2017-08-14 2020-06-24 Axcella Health Inc Acides aminés à chaîne ramifiée pour le traitement d'une maladie du foie
EP3810123A1 (en) 2018-06-20 2021-04-28 Axcella Health Inc. Compositions and methods for the treatment of fat infiltration in muscle
WO2022191184A1 (ja) * 2021-03-08 2022-09-15 国立大学法人九州大学 グレリン受容体感受性増強剤、グレリン受容体感受性増強用組成物及びグレリン受容体の活性化方法
EP4449875A1 (en) 2023-04-18 2024-10-23 Mars, Incorporated Composition for use for improving or preserving mental health in canine

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2018A (en) * 1841-03-26 Joseph francis
US6294520B1 (en) † 1989-03-27 2001-09-25 Albert T. Naito Material for passage through the blood-brain barrier
GB2268871A (en) * 1992-07-04 1994-01-26 Bio Nutritional Health Service Composition for use as a food or food supplement
IT1264987B1 (it) * 1993-12-14 1996-10-17 Prospa Bv Sali di un acido grasso poliinsaturo e formulazioni farmaceutiche che li contengono
ATE191615T1 (de) † 1995-02-23 2000-04-15 Novartis Nutrition Ag Aminosäurenzusammensetzungen und verwendung derselben klinischen nährung
CA2185983C (en) 1996-09-19 2004-04-13 Wie-Jong Kwak Process of extracting and purifying biologically effective ingredients from combined medicinal plants and their extract composition
US5874471A (en) * 1997-02-27 1999-02-23 Waugh; William Howard Orthomolecular medical use of L-citrulline for vasoprotection, relaxative smooth muscle tone and cell protection
US7135498B1 (en) * 1999-06-14 2006-11-14 Henry Ford Health System Nitric oxide donors for inducing neurogenesis
NZ516513A (en) * 1999-06-14 2004-03-26 Ford Henry Health System Nitric oxide donors for inducing neurogenesis
JP4669095B2 (ja) 1999-07-19 2011-04-13 太陽化学株式会社 ペットの問題行動抑制組成物
US20040043013A1 (en) * 2000-12-28 2004-03-04 Mccleary Edward Larry Metabolic uncoupling therapy
US20050002992A1 (en) † 2003-06-17 2005-01-06 Mccleary Edward Larry Foods, beverages, condiments, spices and salad dressings with specialized supplements
DE60220899T2 (de) 2001-03-23 2008-03-13 Ajinomoto Co., Inc. Mittel gegen stressinduzierte krankheiten
US20060014773A1 (en) * 2001-04-19 2006-01-19 Mccleary Edward L Mental agility lozenge, edible strip, food or drink
US6964969B2 (en) * 2001-04-19 2005-11-15 Mccleary Edward Larry Composition and method for treating impaired or deteriorating neurological function
DE10131516B4 (de) † 2001-07-02 2004-05-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Steuereinheit zur Flussregulierung
AU2002336638A1 (en) † 2001-10-12 2003-04-28 Cornell Research Foundation, Inc. Reversing or preventing premature vascular senescence
NL1019368C2 (nl) 2001-11-14 2003-05-20 Nutricia Nv Preparaat voor het verbeteren van receptorwerking.
US7514107B2 (en) * 2002-03-21 2009-04-07 Mars, Incorporated Treatment of diseases involving defective gap junctional communication
US20040001817A1 (en) † 2002-05-14 2004-01-01 Giampapa Vincent C. Anti-aging nutritional supplement
US20040087490A1 (en) * 2002-09-20 2004-05-06 Troup John P. Nutritional compositions
PL377614A1 (pl) 2003-03-18 2006-02-06 Novartis Ag Kompozycje zawierające kwasy tłuszczowe i aminokwasy
WO2005006877A1 (en) † 2003-07-03 2005-01-27 Hill's Pet Nutrition, Inc. Compositions and methods for decreasing age-related deterioration in metal activities in companion animals
US6951658B1 (en) † 2003-07-08 2005-10-04 Pearson Research & Development Limited Emu-based compositions for mental well-being and method of use
JP4699901B2 (ja) 2003-09-02 2011-06-15 ジェレックスインターナショナル株式会社 体脂肪代謝機能と燃焼エネルギーの活用機能とを備えているダイエット用添加物質
CN1898370A (zh) 2003-12-22 2007-01-17 湧永制药株式会社 油脂组合物
US20060002985A1 (en) † 2004-07-02 2006-01-05 Zicker Steven C Compositions and methods for decreasing age-related deterioration in mental activities in companion animals
EP1634599A1 (en) 2004-08-20 2006-03-15 N.V. Nutricia Iimmune stimulatory infant nutrition
AU2005322015B2 (en) † 2004-12-29 2010-02-25 Hill's Pet Nutrition, Inc. Methods for inhibiting a decline in learning and/or memory in animals
RU2362323C2 (ru) 2004-12-30 2009-07-27 Хилл`С Пет Ньютришн, Инк. Способ повышения качества жизни растущего животного и применение композиции для них
CN102907561A (zh) † 2004-12-30 2013-02-06 希尔氏宠物营养品公司 提高老年动物的生活质量的方法
US8324276B2 (en) * 2005-01-24 2012-12-04 Pronova Biopharma Norge As Fatty acid composition for treatment of alzheimer's disease and cognitive dysfunction
CN1810257A (zh) * 2005-05-26 2006-08-02 钟健琳 活脑素口服液
WO2007004148A2 (en) 2005-06-30 2007-01-11 Koninklijke Philips Electronics N.V. Method and system for selection of information
MX336435B (es) † 2005-07-08 2016-01-19 Dsm Ip Assets Bv Acidos grasos poliinsaturados para el tratamiento de demencia y condiciones relacionadas con pre-demencia.
WO2007022991A1 (en) † 2005-08-26 2007-03-01 Nestec S.A. Compositions and methods for improving functional vascular integrity, cellular survival and reducing apoptosis in ischemia or after ischemic episode in the brain
AU2006299665B2 (en) 2005-09-30 2012-12-13 Nestec S.A. Methods and compositions for improving cognitive function
JP5043677B2 (ja) † 2005-12-02 2012-10-10 持田製薬株式会社 アルツハイマー型認知症予防・治療剤
PL1800675T4 (pl) 2005-12-23 2012-02-29 Nutricia Nv Kompozycja zawierająca wielonienasycone kwasy tłuszczowe, białka, mangan, i/lub molibden oraz nukleozydy/nukleotydy do leczenia otępienia
KR20090003148A (ko) * 2006-04-03 2009-01-09 액세라인크 나이와 관련된 기억 손상의 치료를 위한 케톤 생성조성물의 용도
AU2008307494B2 (en) † 2007-10-04 2013-09-05 Société des Produits Nestlé S.A. Compositions and methods for enhancing cognitive function
EP2939314B1 (en) 2012-12-31 2018-08-29 Mitel Networks Corporation Interface adapter

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