BRPI0613358A8 - ácidos de gordura poli - insaturada para o tratamento da demência e condições relacionadas à pré-demência - Google Patents

ácidos de gordura poli - insaturada para o tratamento da demência e condições relacionadas à pré-demência

Info

Publication number
BRPI0613358A8
BRPI0613358A8 BRPI0613358A BRPI0613358A BRPI0613358A8 BR PI0613358 A8 BRPI0613358 A8 BR PI0613358A8 BR PI0613358 A BRPI0613358 A BR PI0613358A BR PI0613358 A BRPI0613358 A BR PI0613358A BR PI0613358 A8 BRPI0613358 A8 BR PI0613358A8
Authority
BR
Brazil
Prior art keywords
dementia
treatment
conditions related
fat acids
polyunsaturated fat
Prior art date
Application number
BRPI0613358A
Other languages
English (en)
Inventor
A Ellis Lorie
Original Assignee
Dsm Ip Assets Bv
Martek Biosciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv, Martek Biosciences Corp filed Critical Dsm Ip Assets Bv
Publication of BRPI0613358A2 publication Critical patent/BRPI0613358A2/pt
Publication of BRPI0613358A8 publication Critical patent/BRPI0613358A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

ácidos graxos poliinsaturados para o tratamento da demência e condições relacionadas à pré-demência. as composições e métodos para tratamento ou prevenção de demência ou pré-demência relacionada às condições e/ou sintomas ou características de tais condições estão expostas.
BRPI0613358A 2005-07-08 2006-07-07 ácidos de gordura poli - insaturada para o tratamento da demência e condições relacionadas à pré-demência BRPI0613358A8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US69791105P 2005-07-08 2005-07-08
US60/697,911 2005-07-08
US77914506P 2006-03-02 2006-03-02
US60/779,145 2006-03-02
PCT/US2006/026331 WO2007008586A2 (en) 2005-07-08 2006-07-07 Polyunsaturated fatty acids for treatment of dementia and pre-dementia-related conditions

Publications (2)

Publication Number Publication Date
BRPI0613358A2 BRPI0613358A2 (pt) 2011-01-04
BRPI0613358A8 true BRPI0613358A8 (pt) 2017-12-26

Family

ID=37637739

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0613358A BRPI0613358A8 (pt) 2005-07-08 2006-07-07 ácidos de gordura poli - insaturada para o tratamento da demência e condições relacionadas à pré-demência

Country Status (12)

Country Link
US (3) US20070032548A1 (pt)
EP (1) EP1904049B1 (pt)
JP (4) JP2009502745A (pt)
KR (5) KR20130101596A (pt)
CN (2) CN103211807A (pt)
AU (1) AU2006269405B2 (pt)
BR (1) BRPI0613358A8 (pt)
CA (1) CA2614473C (pt)
ES (1) ES2617577T3 (pt)
MX (1) MX336435B (pt)
RU (1) RU2444356C2 (pt)
WO (1) WO2007008586A2 (pt)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI120720B (fi) * 2006-06-16 2010-02-15 Neurofood Ab Oy Maitopohjaisia elintarvikkeita, jotka sisältävät keskushermoston lipidejä
EP2578692B1 (en) 2007-04-05 2016-06-08 The J. David Gladstone Institutes Agents that reduce neuronal overexcitation
KR101409115B1 (ko) 2007-06-08 2014-06-17 엘지전자 주식회사 다중 안테나 시스템에서 가중치 정보 전송 방법
WO2009002148A1 (en) 2007-06-27 2008-12-31 N.V. Nutricia Food composition for prodromal dementia patients
WO2009002145A1 (en) 2007-06-26 2008-12-31 N.V. Nutricia Lipid composition for improving function of brain functioning
WO2009002146A1 (en) 2007-06-26 2008-12-31 N.V. Nutricia Supporting activities of daily living
PT2170316E (pt) * 2007-06-26 2014-01-30 Nutricia Nv Melhoramento de memória em indivíduos com exame de estado mini mental de 24-26
AU2008280806B2 (en) * 2007-07-26 2014-12-11 Phenomenome Discoveries Inc. Methods for the diagnosis, risk assessment, and monitoring of autism spectrum disorders
US20090247860A1 (en) * 2007-10-25 2009-10-01 Research Foundation Of State University Of New York Spectral biomarker and algorithm for the identification and detection of neural stem and progenitor cells and their use in studying mammalian brains
US8343753B2 (en) 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
EP2211881A4 (en) * 2007-11-01 2012-01-04 Wake Forest University School Of Medicine COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING DISEASES AFFECTING MAMMALS
WO2009057994A1 (en) 2007-11-02 2009-05-07 N.V. Nutricia Unit dosage for brain health
MX2010006829A (es) 2007-12-20 2010-09-30 Nutricia Nv Producto que contiene nucleotidos/nucleosidos liquidos.
CA2709660C (en) 2008-01-04 2018-06-05 Nestec S.A. Compositions comprising unsaturated fatty acids and nitric oxide releasing compounds and use thereof for enhancing cognitive and related functions
WO2009158148A1 (en) * 2008-05-30 2009-12-30 The Trustees Of Columbia University In The City Of New York Methods for diagnosis and treatment of neurodegenerative diseases or disorders
CA2751275A1 (en) * 2009-02-02 2010-08-05 Martek Biosciences Corporation Use of docosahexaenoic acid in treating mild cognitive impairment
CN102106150A (zh) * 2009-02-05 2011-06-22 松下电器产业株式会社 摄像处理装置
ES2345241B1 (es) * 2009-03-16 2011-09-08 Lipopharma Therapeutics Uso de 2-hidroxiderivados de acidos grasos poliinsaturados como medicamentos.
CN102395366A (zh) * 2009-04-14 2012-03-28 金·尼古拉斯·格林 降低前ADAM10分泌酶和/或β分泌酶水平的方法
JP5872453B2 (ja) * 2009-04-17 2016-03-01 ナタク ファルマ エセ．エレ． フィタン酸含量が低く、ω−３脂肪酸に富む組成物
WO2011006144A1 (en) 2009-07-10 2011-01-13 Martek Biosciences Corporation Methods of treating and preventing neurological disorders using docosahexaenoic acid
WO2011041710A2 (en) 2009-10-01 2011-04-07 Martek Biosciences Corporation Docosahexaenoic acid gel caps
EP2488190B1 (en) * 2009-10-13 2017-09-20 DSM IP Assets B.V. Reducing the risk of pathological effects of traumatic brain injury
EP2493296B1 (en) 2009-10-30 2019-01-09 Retrotope, Inc. Alleviating oxidative stress disorders with pufa derivatives
US20110223246A1 (en) * 2010-03-10 2011-09-15 Joar Opheim Docosahexaenoic acid bound in phospholipids and method of recovering same from a natural source
US8715648B2 (en) 2011-02-16 2014-05-06 Pivotal Therapeutics Inc. Method for treating obesity with anti-obesity formulations and omega 3 fatty acids for the reduction of body weight in cardiovascular disease patients (CVD) and diabetics
US9119826B2 (en) 2011-02-16 2015-09-01 Pivotal Therapeutics, Inc. Omega 3 fatty acid for use as a prescription medical food and omega 3 fatty acid diagniostic assay for the dietary management of cardiovascular patients with cardiovascular disease (CVD) who are deficient in blood EPA and DHA levels
US8952000B2 (en) 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Cholesterol absorption inhibitor and omega 3 fatty acids for the reduction of cholesterol and for the prevention or reduction of cardiovascular, cardiac and vascular events
US8951514B2 (en) 2011-02-16 2015-02-10 Pivotal Therapeutics Inc. Statin and omega 3 fatty acids for reduction of apolipoprotein-B levels
AU2012249918B2 (en) 2011-04-26 2017-06-15 Biojiva Llc Impaired energy processing disorders and mitochondrial deficiency
KR102020611B1 (ko) * 2011-04-26 2019-09-10 레트로토프 인코포레이티드 Ｐｕｆａ와 관련된 신경퇴행성 질환 및 근육 질환
EP3689342A1 (en) 2011-04-26 2020-08-05 Retrotope, Inc. Oxidative retinal diseases
US10154978B2 (en) 2011-04-26 2018-12-18 Retrotope, Inc. Disorders implicating PUFA oxidation
ES2496341T3 (es) 2011-10-04 2014-09-18 Affiris Ag Procedimiento para detectar anticuerpos Aß-específicos en una muestra biológica
EP2819650A1 (en) * 2012-02-29 2015-01-07 B. Braun Melsungen AG Hormone containing emulsion comprising krill phospholipids
JP5986440B2 (ja) * 2012-07-05 2016-09-06 国立医薬品食品衛生研究所長 アルツハイマー病の発症を予測する方法
US20140203176A1 (en) * 2013-01-23 2014-07-24 Dow Agrosciences Llc Systems and methods for real-time sampling and analysis of biomolecules beneath the surface of biological tissue
CN103217463A (zh) * 2013-03-14 2013-07-24 中南大学 一种用于bace1抑制剂筛选的电化学方法
WO2015005443A1 (ja) 2013-07-10 2015-01-15 ライオン株式会社 内服組成物
CN104368002B (zh) * 2014-10-17 2019-01-08 中国人民解放军军事医学科学院毒物药物研究所 用于治疗痴呆或认知功能障碍的联合用药物
WO2016112174A2 (en) * 2015-01-08 2016-07-14 The Trustees Of The University Of Pennsylvania Biomarkers of Sleep Deprivation and Cognitive Impairment
KR20170025977A (ko) * 2015-08-31 2017-03-08 재단법인차세대융합기술연구원 옥시리스 마리나로부터 분리된 신규 화합물
WO2017044807A2 (en) 2015-09-09 2017-03-16 The Trustees Of Columbia University In The City Of New York Reduction of er-mam-localized app-c99 and methods of treating alzheimer's disease
WO2017091279A1 (en) 2015-11-23 2017-06-01 Retrotope, Inc. Site-specific isotopic labeling of 1, 4-diene systems
IL283779B (en) * 2015-11-24 2022-09-01 Massachusetts Inst Technology Systems and methods for preventing, alleviating and/or treating dementia
US20190314442A1 (en) * 2016-02-22 2019-10-17 Newtricious B.V. Composition for the prevention or treatment of neurodegenerative diseases
CN106617064A (zh) * 2016-12-22 2017-05-10 徐晓飞 一种含姜黄素和ω‑3多不饱和脂肪酸的组合物及其应用
CN106666745A (zh) * 2016-12-22 2017-05-17 徐晓飞 一种含姜黄素和dha的组合物及应用
CN110381966A (zh) 2017-03-06 2019-10-25 刘军 Aβ-诱导的损伤的抑制或减轻药剂
US11065288B2 (en) 2017-09-29 2021-07-20 Kinjirushi Co., Ltd. Neuron activator
FR3092968B1 (fr) * 2019-02-22 2021-05-21 Microphyt Complement alimentaire
CA3172351A1 (en) 2020-02-21 2021-08-26 Retrotope, Inc. Processes for isotopic modification of polyunsaturated fatty acids and derivatives thereof
KR102466479B1 (ko) 2020-03-30 2022-11-15 주식회사 뷰브레인헬스케어 타우 단백질 축적 예측 장치 및 이를 이용한 타우 단백질 축적 예측 방법
CN114680336A (zh) * 2020-12-30 2022-07-01 云南汉盟制药有限公司 一种含火麻仁不饱和脂肪酸的滴剂及其制备方法
CN112798727B (zh) * 2021-04-09 2021-07-06 宝枫生物科技（北京）有限公司 用于诊断脑白质病变的生物标志物f7及其应用
WO2023154484A1 (en) * 2022-02-11 2023-08-17 Retrotope, Inc. Methods for monitoring patient response to treatment of retinal oxidative diseases

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4058594A (en) * 1974-04-25 1977-11-15 John Williams Immuno-suppressive agents
GB8601915D0 (en) * 1986-01-27 1986-03-05 Efamol Ltd Pharmaceutical compositions
US5198468A (en) * 1987-06-24 1993-03-30 Efamol Holdings Plc Essential fatty acid composition
JP2524217B2 (ja) * 1988-04-18 1996-08-14 マルハ株式会社 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤または痴呆治療剤
US5407957A (en) * 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
GB9300125D0 (en) * 1993-01-06 1993-03-03 Scotia Holdings Plc Compositions containing esters of unsaturated fatty acids
US5408326A (en) * 1993-04-28 1995-04-18 Shell Oil Company Dual-wavelength absorption detector adapted for continuous-flow detection
US5403826A (en) * 1993-05-28 1995-04-04 Abbott Laboratories Nutritional product for persons infected with human immunodeficiency virus
DE19529795C2 (de) 1994-08-16 1998-09-10 Frische Gmbh Verfahren zur Gewinnung von nicht wasserlöslichen, nativen Produkten aus Stoffgemengen mit Hilfe der Zentrifugalkraft
IT1274734B (it) * 1994-08-25 1997-07-24 Prospa Bv Composizioni farmaceutiche contenenti acidi grassi poliinsaturi, loro esteri o sali, unitamente a vitamine o provitamine antiossidanti
JP3985035B2 (ja) * 1995-09-14 2007-10-03 独立行政法人産業技術総合研究所 （ｎ−６）系ドコサペンタエン酸含有油脂ならびに該油脂の製造方法および用途
AU723553C (en) * 1996-07-23 2005-04-14 Nagase & Co., Ltd. Process for preparing docosahexaenoic acid and docosapentaenoic acid
SK285210B6 (sk) * 1996-10-11 2006-09-07 Scarista Limited Farmaceutický prípravok na liečenie schizofrénie a použitie oleja obsahujúceho kyselinu eikozapentaenovú alebo stearidonovú, alebo ich kombináciu na prípravu tohto liečiva
US6528529B1 (en) * 1998-03-31 2003-03-04 Acadia Pharmaceuticals Inc. Compounds with activity on muscarinic receptors
US6191154B1 (en) * 1998-11-27 2001-02-20 Case Western Reserve University Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases
GB9901809D0 (en) * 1999-01-27 1999-03-17 Scarista Limited Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes
US6596766B1 (en) * 1999-03-04 2003-07-22 Suntory Limited Utilization of material containing docosapentaenoic acid
CA2311974A1 (en) * 1999-06-28 2000-12-28 Nisshin Flour Milling Co., Ltd. Processes of selectively separating and purifying eicosapentaenoic and docosahexaenoic acids or their esters
AU2001232786A1 (en) * 2000-01-11 2001-07-24 Monsanto Company Process for making an enriched mixture of polyunsaturated fatty acid esters
CN100403917C (zh) 2000-04-12 2008-07-23 威斯特伐利亚分离器股份公司 含油和极性脂质的天然原料的分级分离方法
US20070179197A1 (en) * 2000-05-01 2007-08-02 Accera, Inc. Compositions and methods for improving or preserving brain function
JP4629834B2 (ja) * 2000-05-12 2011-02-09 備前化成株式会社 神経細胞賦活剤およびその利用
US20060275294A1 (en) * 2002-08-22 2006-12-07 Omoigui Osemwota S Method of prevention and treatment of aging, age-related disorders and/or age-related manifestations including atherosclerosis, peripheral vascular disease, coronary artery disease, osteoporosis, arthritis, type 2 diabetes, dementia, alzheimers disease and cancer
EP1558237A4 (en) * 2002-09-27 2007-01-17 Martek Biosciences Corp IMPROVED GLYCEMIC REGULATION IN PREDIABETE AND / OR DIABETES TYPE II USING DOCOSAHEXAENOIC ACID
NZ539624A (en) * 2002-09-27 2008-08-29 Martek Biosciences Corp Prophylactic docosahexaenoic acid therapy for patients with subclinical inflammation
US20050265983A1 (en) * 2002-11-17 2005-12-01 Eldad Melamed Methods, nucleic acid constructs and cells for treating neurodegenerative disorders
US20050031651A1 (en) * 2002-12-24 2005-02-10 Francine Gervais Therapeutic formulations for the treatment of beta-amyloid related diseases
US7935365B2 (en) * 2003-10-22 2011-05-03 Enzymotec, Ltd. Glycerophospholipids for the improvement of cognitive functions
US20050249823A1 (en) * 2003-11-04 2005-11-10 Murphy Tanya K Methods for the prevention or amelioration of neuropsychiatric and related diseases
AU2005208832A1 (en) * 2004-01-19 2005-08-11 Martek Biosciences Corporation Reelin deficiency or dysfunction and methods related thereto
US20060020031A1 (en) * 2004-07-26 2006-01-26 Roger Berlin Compositions containing policosanol and omega-3 fatty acids and their pharmaceutical uses
WO2006055965A2 (en) * 2004-11-19 2006-05-26 Martek Biosciences Corporation Oxylipins from long chain polyunsaturated fatty acids and methods of making and using the same
US8324276B2 (en) * 2005-01-24 2012-12-04 Pronova Biopharma Norge As Fatty acid composition for treatment of alzheimer's disease and cognitive dysfunction
DE102005003625A1 (de) * 2005-01-26 2006-07-27 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Verfahren zur Herstellung einer DHA-haltigen Fettsäure-Zusammensetzung
US20060270739A1 (en) * 2005-04-28 2006-11-30 Trustees Of Tufts College Synergistic effects of docosahexaenoic acid (DHA) and carotenoid absorption on macular pigmentation
WO2006117664A1 (en) * 2005-05-04 2006-11-09 Pronova Biopharma Norge As New dha derivatives and their use as medicaments
ES2264886B1 (es) * 2005-05-12 2008-02-01 Proyecto Empresarial Brudy, S.L. Utilizacion de acido docosahexaenoico para el tratamiento de enfermedades tumorales.
HUE031206T2 (en) * 2005-05-23 2017-06-28 Massachusetts Inst Technology Formulations and methods of application containing PUFA
US20070042953A1 (en) * 2005-08-16 2007-02-22 Bazan Nicolas G Antiepileptogenic complex of albumin with docosahexaenoate
US20070060651A1 (en) * 2005-08-26 2007-03-15 Nestec S.A. Compositions and methods for improving functional vascular cellular survival integrity and reducing apoptosis in ischemia
MX2010000263A (es) * 2007-06-29 2010-03-11 Martek Biosciences Corp Produccion y purificacion de esteres de acidos grasos poliinsaturados.

Also Published As

Publication number Publication date
US20070032548A1 (en) 2007-02-08
EP1904049A4 (en) 2012-08-01
CA2614473C (en) 2016-05-03
US20110218242A1 (en) 2011-09-08
MX336435B (es) 2016-01-19
CN101262863B (zh) 2016-08-31
JP2013056900A (ja) 2013-03-28
US20150119464A1 (en) 2015-04-30
ES2617577T3 (es) 2017-06-19
BRPI0613358A2 (pt) 2011-01-04
AU2006269405A1 (en) 2007-01-18
KR101870626B1 (ko) 2018-06-26
KR20190014122A (ko) 2019-02-11
AU2006269405B2 (en) 2013-01-17
KR20080027384A (ko) 2008-03-26
JP2009502745A (ja) 2009-01-29
KR20160116351A (ko) 2016-10-07
CA2614473A1 (en) 2007-01-18
KR20130101596A (ko) 2013-09-13
EP1904049A2 (en) 2008-04-02
KR20180026556A (ko) 2018-03-12
RU2444356C2 (ru) 2012-03-10
CN103211807A (zh) 2013-07-24
MX2008000178A (es) 2008-04-07
JP2018021078A (ja) 2018-02-08
EP1904049B1 (en) 2016-12-07
KR101965124B1 (ko) 2019-04-02
WO2007008586A3 (en) 2007-04-12
JP2015147775A (ja) 2015-08-20
RU2008104697A (ru) 2009-08-20
WO2007008586A2 (en) 2007-01-18
CN101262863A (zh) 2008-09-10

Similar Documents

Publication Publication Date Title
BRPI0613358A8 (pt) ácidos de gordura poli - insaturada para o tratamento da demência e condições relacionadas à pré-demência
BRPI0512864A (pt) composições e métodos para o tratamento de condições e desordens oculares
CR9528A (es) Inhibitors of microsomal triglyceride transfer protein and apo-b secretion
BRPI0519424A2 (pt) composiÇÕes e mÉtodos para tratamento de distérbios de proliferaÇço celular
CR20140422A (es) Composiciones de enzima digestiva estable
DE602007012133D1 (de) Triazolopyridinverbindungen zur behandlung von degenerations- und entzündungskrankheiten
CY1109985T1 (el) Αναστολεις πρωτεασωματος και μεθοδοι χρησης αυτων
HK1136283A1 (en) Compounds for the prevention and treatment of cardiovascular diseases
EA201500530A1 (ru) 1,2,5-оксадиазолы в качестве ингибиторов индоламин-2,3-диоксигеназы
BRPI0516645A (pt) composições de perfume
WO2008002571A3 (en) Human protein tyrosine phosphatase inhibitors and methods of use
BRPI0607017A2 (pt) métodos e composições para o tratamento de condições relacionadas ao snc
EA200901166A1 (ru) Соединения и композиции в качестве модуляторов активности gpr 119
ECSP066986A (es) Beta-carbolinas utiles para tratar enfermedades inflamatorias
TN2010000140A1 (en) Compositions and methods for use antibodies against sclerostin
ATE538651T1 (de) Spiropiperidininhibitoren von beta-secretase zur behandlung von alzheimer-krankheit
ATE555116T1 (de) Ahcy-hydrolasehemmer zur behandlung von hyperhomocysteinämie
TW200942549A (en) Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of TRPV1
DE60141636D1 (de) Phospholipidderivate von valproinsäure und ihre kombinationen
ATE472998T1 (de) Kationische liposomale zubereitungen zur behandlung von rheumatoider arthritis
IN2015DN03331A (pt)
WO2008011178A3 (en) Compositions comprising omega-3 fatty acids, and their use in treating peripheral artery disease and intermittent claudication
BRPI0814808B8 (pt) processo para preparação de óleo ou manteiga de sapucainha e uso de óleo ou manteiga de sapucainha
WO2007135518A3 (en) Use of choline-based preparations for the treatment of tinnitus
NO20076426L (no) Aktiv sammensetning for behandling eller for a unnga problemer relatert til forstyrrelse av den biologiske klokken

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: DSM IP ASSETS B.V. (NL)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]