WO2008011178A3 - Compositions comprising omega-3 fatty acids, and their use in treating peripheral artery disease and intermittent claudication - Google Patents

Compositions comprising omega-3 fatty acids, and their use in treating peripheral artery disease and intermittent claudication Download PDF

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Publication number
WO2008011178A3
WO2008011178A3 PCT/US2007/016526 US2007016526W WO2008011178A3 WO 2008011178 A3 WO2008011178 A3 WO 2008011178A3 US 2007016526 W US2007016526 W US 2007016526W WO 2008011178 A3 WO2008011178 A3 WO 2008011178A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
intermittent claudication
omega
fatty acids
artery disease
Prior art date
Application number
PCT/US2007/016526
Other languages
French (fr)
Other versions
WO2008011178A2 (en
Inventor
Roelof M L Rongen
Robert A Ms Shalwitz
Original Assignee
Reliant Pharmaceuticals Inc
Roelof M L Rongen
Robert A Ms Shalwitz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reliant Pharmaceuticals Inc, Roelof M L Rongen, Robert A Ms Shalwitz filed Critical Reliant Pharmaceuticals Inc
Priority to JP2009521785A priority Critical patent/JP2009544701A/en
Priority to EP07810680A priority patent/EP2068861A4/en
Publication of WO2008011178A2 publication Critical patent/WO2008011178A2/en
Publication of WO2008011178A3 publication Critical patent/WO2008011178A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Compositions comprising omega-3 fatty acids, where the compositions are useful for treating intermittent claudication, preventing its further progression, and treating underlying conditions such as PAD that cause IC symptoms, methods of making such compositions, methods of using the compositions to treat intermittent claudication, and methods of using the compositions to treat any of the various underlying conditions that cause intermittent claudication.
PCT/US2007/016526 2006-07-21 2007-07-23 Compositions comprising omega-3 fatty acids, and their use in treating peripheral artery disease and intermittent claudication WO2008011178A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2009521785A JP2009544701A (en) 2006-07-21 2007-07-23 Compositions containing omega-3 fatty acids and their use to treat peripheral arterial injury and intermittent claudication
EP07810680A EP2068861A4 (en) 2006-07-21 2007-07-23 Compositions comprising omega-3 fatty acids, and their use in treating peripheral artery disease and intermittent claudication

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83213506P 2006-07-21 2006-07-21
US60/832,135 2006-07-21

Publications (2)

Publication Number Publication Date
WO2008011178A2 WO2008011178A2 (en) 2008-01-24
WO2008011178A3 true WO2008011178A3 (en) 2008-06-12

Family

ID=38957420

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/016526 WO2008011178A2 (en) 2006-07-21 2007-07-23 Compositions comprising omega-3 fatty acids, and their use in treating peripheral artery disease and intermittent claudication

Country Status (3)

Country Link
EP (1) EP2068861A4 (en)
JP (1) JP2009544701A (en)
WO (1) WO2008011178A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8343753B2 (en) 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
NZ595204A (en) * 2009-03-09 2014-11-28 Pronova Biopharma Norge As Compositions comprising a fatty acid oil mixture and a surfactant, and methods and uses thereof
WO2016152054A1 (en) * 2015-03-26 2016-09-29 備前化成株式会社 Pain prevention and alleviation effects of ω3 fatty acid glyceride
MA52680A1 (en) * 2018-08-17 2021-11-30 Amarin Pharmaceuticals Ie Ltd Methods of reducing the need for peripheral arterial revascularization in a subject treated with statins
WO2022225896A1 (en) 2021-04-21 2022-10-27 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of heart failure

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5532003A (en) * 1994-01-18 1996-07-02 Alza Corporation Pentoxifylline therapy
US5698594A (en) * 1988-08-11 1997-12-16 Norsk Hydro A.S Treatment and prevention of risk factors for cardiovascular diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020055539A1 (en) * 1996-10-02 2002-05-09 Bockow Barry I. Compositions and methods for treating cardiovascular conditions
EP1125914A1 (en) * 2000-02-14 2001-08-22 Nisshin Flour Milling Co., Ltd. Process for separating and purifying eicosapentaenoic acid or its ester
WO2006062748A2 (en) * 2004-12-06 2006-06-15 Reliant Pharmaceuticals, Inc. Omega-3 fatty acids and dyslipidemic agent for lipid therapy
CN101098690A (en) * 2004-12-06 2008-01-02 瑞莱恩特医药品有限公司 Omega-3 fatty acids and dyslipidemic agent for lipid therapy
CA2600429A1 (en) * 2005-03-08 2006-09-14 Reliant Pharmaceuticals, Inc. Treatment with statin and omega-3 fatty acids and a combination product thereof
BRPI0612908A2 (en) * 2005-07-18 2010-12-07 Reliant Phamaceuticals Inc pharmaceutical compositions comprising azetidinone-based cholesterol absorption inhibitors and omega-3 fatty acids and methods of treatment using them

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698594A (en) * 1988-08-11 1997-12-16 Norsk Hydro A.S Treatment and prevention of risk factors for cardiovascular diseases
US5532003A (en) * 1994-01-18 1996-07-02 Alza Corporation Pentoxifylline therapy

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CARRERO ET AL.: "Daily Supplementation with (n-3) PUFAs, Oleic Acid, Folic Acid, and Vitamins B-6 and E increase Pain-Free Walking Distance and Improves Risk Factors in Men with Peripheral Vascular Disease", JOURNAL OF NUTRITION, vol. 135, no. 6, June 2005 (2005-06-01), pages 1393 - 1399, XP008103124 *
See also references of EP2068861A4 *

Also Published As

Publication number Publication date
EP2068861A4 (en) 2010-01-06
JP2009544701A (en) 2009-12-17
EP2068861A2 (en) 2009-06-17
WO2008011178A2 (en) 2008-01-24

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