JP5960121B2 - Streptococcus agalactiaeの処置および予防のための免疫原性タンパク質および組成物 - Google Patents

Streptococcus agalactiaeの処置および予防のための免疫原性タンパク質および組成物 Download PDF

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JP5960121B2
JP5960121B2 JP2013502028A JP2013502028A JP5960121B2 JP 5960121 B2 JP5960121 B2 JP 5960121B2 JP 2013502028 A JP2013502028 A JP 2013502028A JP 2013502028 A JP2013502028 A JP 2013502028A JP 5960121 B2 JP5960121 B2 JP 5960121B2
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amino acid
polypeptide
acid sequence
sequence
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JP2013523718A5 (cg-RX-API-DMAC7.html
JP2013523718A (ja
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ギード グランディ,
ギード グランディ,
ドメニコ マイオーネ,
ドメニコ マイオーネ,
チーラ ダニエラ リナウド,
チーラ ダニエラ リナウド,
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ノバルティス アーゲー
ノバルティス アーゲー
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1275Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2013502028A 2010-04-01 2011-04-01 Streptococcus agalactiaeの処置および予防のための免疫原性タンパク質および組成物 Expired - Fee Related JP5960121B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1005625.7 2010-04-01
GBGB1005625.7A GB201005625D0 (en) 2010-04-01 2010-04-01 Immunogenic proteins and compositions
PCT/IB2011/051415 WO2011121576A2 (en) 2010-04-01 2011-04-01 Immunogenic proteins and compositions

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JP2016024416A Division JP2016098231A (ja) 2010-04-01 2016-02-12 Streptococcusagalactiaeの処置および予防のための免疫原性タンパク質および組成物

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JP2013523718A JP2013523718A (ja) 2013-06-17
JP2013523718A5 JP2013523718A5 (cg-RX-API-DMAC7.html) 2014-02-20
JP5960121B2 true JP5960121B2 (ja) 2016-08-02

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JP2016024416A Withdrawn JP2016098231A (ja) 2010-04-01 2016-02-12 Streptococcusagalactiaeの処置および予防のための免疫原性タンパク質および組成物

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US (4) US9079946B2 (cg-RX-API-DMAC7.html)
EP (1) EP2552477B1 (cg-RX-API-DMAC7.html)
JP (2) JP5960121B2 (cg-RX-API-DMAC7.html)
CN (1) CN102917729B (cg-RX-API-DMAC7.html)
AU (1) AU2011234031B2 (cg-RX-API-DMAC7.html)
CA (1) CA2795093A1 (cg-RX-API-DMAC7.html)
ES (1) ES2740000T3 (cg-RX-API-DMAC7.html)
GB (1) GB201005625D0 (cg-RX-API-DMAC7.html)
MX (2) MX349948B (cg-RX-API-DMAC7.html)
NZ (1) NZ602693A (cg-RX-API-DMAC7.html)
SG (2) SG10201502583VA (cg-RX-API-DMAC7.html)
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GB201005625D0 (en) * 2010-04-01 2010-05-19 Novartis Ag Immunogenic proteins and compositions
AR101455A1 (es) * 2014-08-05 2016-12-21 Glaxosmithkline Biologicals Sa Molécula portadora
EP3439704A1 (en) 2016-04-05 2019-02-13 GSK Vaccines S.r.l. Immunogenic compositions
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
WO2018229708A1 (en) 2017-06-16 2018-12-20 Glaxosmithkline Biologicals Sa Method of treatment
GB201711274D0 (en) 2017-07-13 2017-08-30 Glaxosmithkline Biologicals Sa Novel intermediates for the preperation of GBS polysaccharide antigens
CN108840914B (zh) * 2018-08-13 2022-07-01 内蒙古民族大学 一种具有免疫原性的多肽、其抗体的制备方法以及用途
WO2021099982A1 (en) 2019-11-22 2021-05-27 Glaxosmithkline Biologicals Sa Dosage and administration of a bacterial saccharide glycoconjugate vaccine
WO2021250625A2 (en) 2020-06-12 2021-12-16 Glaxosmithkline Biologicals Sa Gbs ferritin nanoparticles
EP4247828A1 (en) 2020-11-20 2023-09-27 Institut Pasteur Protected disaccharides, their process of preparation and their use in the synthesis of zwitterionic oligosaccharides, and conjugates thereof
CN115057944B (zh) * 2022-06-24 2025-06-24 南京农业大学 一种针对所有gbs血清型的多表位亚单位疫苗
GB202215634D0 (en) * 2022-10-21 2022-12-07 Glaxosmithkline Biologicals Sa Polypeptide scaffold

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CA2795093A1 (en) 2011-10-06
US9458229B2 (en) 2016-10-04
US10086060B2 (en) 2018-10-02
AU2011234031A1 (en) 2012-10-25
US20160362457A1 (en) 2016-12-15
JP2016098231A (ja) 2016-05-30
US20130071416A1 (en) 2013-03-21
CN102917729A (zh) 2013-02-06
SG184151A1 (en) 2012-10-30
WO2011121576A3 (en) 2011-12-29
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WO2011121576A2 (en) 2011-10-06
MX349948B (es) 2017-08-22
US20150343051A1 (en) 2015-12-03
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US20170296645A1 (en) 2017-10-19
US9725488B2 (en) 2017-08-08
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US9079946B2 (en) 2015-07-14
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