JP5914344B2 - Staphylococcusaureus5型および8型の莢膜糖の精製 - Google Patents

Staphylococcusaureus5型および8型の莢膜糖の精製 Download PDF

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Publication number
JP5914344B2
JP5914344B2 JP2012536006A JP2012536006A JP5914344B2 JP 5914344 B2 JP5914344 B2 JP 5914344B2 JP 2012536006 A JP2012536006 A JP 2012536006A JP 2012536006 A JP2012536006 A JP 2012536006A JP 5914344 B2 JP5914344 B2 JP 5914344B2
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polysaccharide
antigen
seq
type
aureus
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JP2013509397A (ja
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パオロ コスタンティーノ,
パオロ コスタンティーノ,
マリア ロザリア ロマノ,
マリア ロザリア ロマノ,
フランチェスコ ベルチ,
フランチェスコ ベルチ,
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ノバルティス アーゲー
ノバルティス アーゲー
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • C07H1/06Separation; Purification
    • C07H1/08Separation; Purification from natural products
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/085Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • External Artificial Organs (AREA)
JP2012536006A 2009-10-30 2010-11-01 Staphylococcusaureus5型および8型の莢膜糖の精製 Expired - Fee Related JP5914344B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25690509P 2009-10-30 2009-10-30
US61/256,905 2009-10-30
PCT/IB2010/054934 WO2011051917A1 (en) 2009-10-30 2010-11-01 Purification of staphylococcus aureus type 5 and type 8 capsular saccharides

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015257722A Division JP2016047852A (ja) 2009-10-30 2015-12-30 Staphylococcusaureus5型および8型の莢膜糖の精製

Publications (2)

Publication Number Publication Date
JP2013509397A JP2013509397A (ja) 2013-03-14
JP5914344B2 true JP5914344B2 (ja) 2016-05-11

Family

ID=43513776

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2012536006A Expired - Fee Related JP5914344B2 (ja) 2009-10-30 2010-11-01 Staphylococcusaureus5型および8型の莢膜糖の精製
JP2015257722A Withdrawn JP2016047852A (ja) 2009-10-30 2015-12-30 Staphylococcusaureus5型および8型の莢膜糖の精製
JP2017168223A Withdrawn JP2017206564A (ja) 2009-10-30 2017-09-01 Staphylococcus aureus 5型および8型の莢膜糖の精製
JP2019072625A Withdrawn JP2019104940A (ja) 2009-10-30 2019-04-05 Staphylococcus aureus 5型および8型の莢膜糖の精製

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2015257722A Withdrawn JP2016047852A (ja) 2009-10-30 2015-12-30 Staphylococcusaureus5型および8型の莢膜糖の精製
JP2017168223A Withdrawn JP2017206564A (ja) 2009-10-30 2017-09-01 Staphylococcus aureus 5型および8型の莢膜糖の精製
JP2019072625A Withdrawn JP2019104940A (ja) 2009-10-30 2019-04-05 Staphylococcus aureus 5型および8型の莢膜糖の精製

Country Status (23)

Country Link
US (5) US9060965B2 (https=)
EP (2) EP3199177A1 (https=)
JP (4) JP5914344B2 (https=)
CN (2) CN109134677A (https=)
AU (1) AU2010310919B2 (https=)
BR (2) BR112012010223A2 (https=)
CA (1) CA2779578A1 (https=)
CL (1) CL2012001145A1 (https=)
CY (1) CY1118905T1 (https=)
DK (1) DK2493498T3 (https=)
ES (1) ES2626416T3 (https=)
HR (1) HRP20170674T1 (https=)
HU (1) HUE034251T2 (https=)
LT (1) LT2493498T (https=)
MX (2) MX345967B (https=)
PL (1) PL2493498T3 (https=)
PT (1) PT2493498T (https=)
RS (1) RS56000B1 (https=)
RU (1) RU2579900C2 (https=)
SG (1) SG10201407096RA (https=)
SI (1) SI2493498T1 (https=)
SM (1) SMT201700275T1 (https=)
WO (1) WO2011051917A1 (https=)

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JP2023546446A (ja) 2020-10-22 2023-11-02 ファイザー・インク 細菌多糖を精製する方法
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US12357681B2 (en) 2020-12-23 2025-07-15 Pfizer Inc. E. coli FimH mutants and uses thereof
CN112986457B (zh) * 2021-02-25 2022-07-12 中国食品药品检定研究院 HPSEC-MALS法检测多糖并与Sepharose CL-4B法关联的方法
CN118345133A (zh) * 2021-06-15 2024-07-16 广州知易生物科技有限公司 脆弱拟杆菌荚膜多糖a的制备方法
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