DK1395648T3 - Fremgangsmåder til binding af AcmA-type proteinankerfusioner til cellevægsmateriale af mikroorganismer - Google Patents

Fremgangsmåder til binding af AcmA-type proteinankerfusioner til cellevægsmateriale af mikroorganismer

Info

Publication number
DK1395648T3
DK1395648T3 DK02741528T DK02741528T DK1395648T3 DK 1395648 T3 DK1395648 T3 DK 1395648T3 DK 02741528 T DK02741528 T DK 02741528T DK 02741528 T DK02741528 T DK 02741528T DK 1395648 T3 DK1395648 T3 DK 1395648T3
Authority
DK
Denmark
Prior art keywords
wall material
cell
acma
binding
methods
Prior art date
Application number
DK02741528T
Other languages
English (en)
Inventor
Ranjan Ramasamy
Anton Steen
Girbe Buist
Cornelis Johannes Leenhouts
Jan Kok
Oscar Paul Kuipers
Original Assignee
Applied Nanosystems Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Nanosystems Bv filed Critical Applied Nanosystems Bv
Application granted granted Critical
Publication of DK1395648T3 publication Critical patent/DK1395648T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/335—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Lactobacillus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK02741528T 2001-06-11 2002-06-11 Fremgangsmåder til binding af AcmA-type proteinankerfusioner til cellevægsmateriale af mikroorganismer DK1395648T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01202239 2001-06-11
PCT/NL2002/000383 WO2002101026A2 (en) 2001-06-11 2002-06-11 Methods for binding acma-type protein anchor fusions to cell-wall material of micro-organisms

Publications (1)

Publication Number Publication Date
DK1395648T3 true DK1395648T3 (da) 2009-08-03

Family

ID=8180461

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02741528T DK1395648T3 (da) 2001-06-11 2002-06-11 Fremgangsmåder til binding af AcmA-type proteinankerfusioner til cellevægsmateriale af mikroorganismer

Country Status (10)

Country Link
US (4) US6896887B2 (da)
EP (1) EP1395648B1 (da)
CN (1) CN100513548C (da)
AT (1) ATE429484T1 (da)
AU (1) AU2002314626B2 (da)
CA (1) CA2450318C (da)
DE (1) DE60232071D1 (da)
DK (1) DK1395648T3 (da)
NZ (1) NZ530527A (da)
WO (1) WO2002101026A2 (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0024200D0 (en) * 2000-10-03 2000-11-15 Smithkline Beecham Sa Component vaccine
ATE429484T1 (de) * 2001-06-11 2009-05-15 Applied Nanosystems Bv Verfahren zur bindung von acma-typ protein anker fusionen an mikroorganismen zellwandmaterialien
US20040224343A1 (en) * 2003-05-06 2004-11-11 Biochain Inc. Methods and products to enhance interactions among molecules
EP1477802A1 (en) * 2003-05-16 2004-11-17 Erasmus Universiteit Rotterdam Method for selecting and producing vaccine components and vaccines based thereon
EP1746103A1 (en) * 2005-07-20 2007-01-24 Applied NanoSystems B.V. Bifunctional protein anchors
WO2008128189A1 (en) * 2007-04-13 2008-10-23 The Penn State Research Foundation Anti-cancer compositions and methods
EP2308506A1 (en) * 2009-10-02 2011-04-13 Mucosis B.V. Adjuvanted intranasal vaccine formulations
EP2485764A4 (en) * 2009-10-09 2014-01-29 Childrens Medical Center WHOLE CELL VACCINE WITH SELECTIVE DISSOCIATION
JP5914344B2 (ja) 2009-10-30 2016-05-11 ノバルティス アーゲー Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ５型および８型の莢膜糖の精製
WO2011060093A2 (en) * 2009-11-10 2011-05-19 National Jewish Health Compositions, methods and uses for stimulating immune responses
WO2012019928A1 (en) 2010-08-13 2012-02-16 Guntram Christiansen Modified peptide display
CA2830901A1 (en) 2011-03-22 2012-09-27 Mucosis B.V. Immunogenic compositions in particulate form and methods for producing the same
WO2013034687A1 (en) 2011-09-09 2013-03-14 Universität Bern Verwaltungsdirektion Avibacterium paragallinarum rtx toxin
CN103013897A (zh) * 2012-10-30 2013-04-03 东北农业大学 一种干酪乳杆菌菌影及其制备方法和应用
US9060975B2 (en) 2013-03-14 2015-06-23 Mucosis Bv Heat-stable respiratory syncytial virus F protein oligomers and their use in immunological compositions
EP3092252B1 (en) * 2014-01-08 2019-09-18 The U.S.A. as represented by the Secretary, Department of Health and Human Services Antibody targeting cell surface deposited complement protein c3d and use thereof
CA2977493C (en) * 2015-03-03 2023-05-16 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Display platform from bacterial spore coat proteins
CN105784984B (zh) * 2016-03-01 2017-12-19 南京财经大学 革兰氏阳性菌菌影的制备方法及其应用
KR101825439B1 (ko) * 2016-04-15 2018-02-05 배재대학교 산학협력단 염산 처리에 의한 그람양성 박테리아 고스트의 제조 방법
CN107417773B (zh) * 2016-05-30 2020-09-08 国盛生化股份有限公司 黏合细胞壁之胜肽
CN105968213A (zh) * 2016-06-14 2016-09-28 长春百克生物科技股份公司 一种肺炎链球菌融合蛋白及其疫苗
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
EP3562838A2 (en) 2016-12-28 2019-11-06 Henriques Normark, Birgitta Microparticles from streptococcus pneumoniae as vaccine antigens
CN107460173B (zh) * 2017-09-08 2020-09-22 江苏省农业科学院 一种纯化猪流行性腹泻病毒、猪繁殖与呼吸综合征病毒或禽流感病毒的方法
WO2019081625A1 (en) 2017-10-25 2019-05-02 Allero Therapeutics Bvba TREATMENT OF IMMUNE DISEASES BY ADMINISTRATION OF ANTIGEN-SPECIFIC FORMULATIONS

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2788987B2 (ja) 1988-08-31 1998-08-20 協同乳業株式会社 免疫賦活作用を有する粗糖蛋白質画分及びその製造法
DE3919644A1 (de) 1989-06-16 1990-12-20 Diagen Inst Molekularbio Mittel zur prophylaktischen und therapeutischen behandlung von viralen infektionen
DE4005874A1 (de) 1990-02-24 1991-11-07 Boehringer Mannheim Gmbh Traegergebundene rekombinante proteine, verfahren zur herstellung und verwendung als immunogene und vakzine
US5821088A (en) 1990-05-11 1998-10-13 Siga Pharmaceuticals, Inc. Use of gram-positive bacteria to express recombinant proteins
US5616686A (en) 1990-05-11 1997-04-01 The Rockefeller University Polypeptide of a hybrid surface protein by bacteria
DE4023721A1 (de) 1990-07-26 1992-01-30 Boehringer Mannheim Gmbh Verfahren zur herstellung von vakzinen und ihre verwendung
US6177083B1 (en) 1990-07-26 2001-01-23 Evax Technologies Gmbh Process for the production of vaccines and their use
IT1252160B (it) * 1991-12-03 1995-06-05 Giuseppe Fichera Composizioni farmaceutiche contenenti il peptidoglicano del lactobacillus casei
RU95105899A (ru) 1992-07-08 1997-03-20 Унилевер Н.В. (NL) Способ иммобилизации фермента, полинуклеотид, вектор, химерный блок, низшие эукариоты, способ осуществления ферментативного процесса
US6114147A (en) 1993-02-10 2000-09-05 Unilever Patent Holdings Immobilized proteins with specific binding capacities and their use in processes and products
JPH10500012A (ja) 1994-05-12 1998-01-06 クウエスト・インターナシヨナル・ベー・ベー 溶解素による乳酸バクテリアの培養物を溶解する方法および得られる溶解培養物の使用
DE4422859C2 (de) 1994-06-30 2000-10-05 Laves Arzneimittel Gmbh Wäßrige Zellextrakte aus Mykobacterien
ATE296877T1 (de) 1994-10-07 2005-06-15 Univ Rockefeller Enzyme zur spaltung der verankerungsregion von oberflächenproteinen aus gram-positiven bakterien
DK0712935T3 (da) 1994-11-18 2002-07-15 Stichting Nl I Voor Zuivelonde Fremgangsmåde til styring af genekspressionen i mælkesyrebakterier
DE19603649A1 (de) 1996-02-01 1997-08-07 Werner Lubitz Rekombinante Expression von S-Layer-Proteinen
DE19633698A1 (de) 1996-08-21 1998-02-26 Lubitz Werner Prof Dr Neue Systeme zur Regulation der Genexpression
JP4049408B2 (ja) 1996-10-24 2008-02-20 株式会社ヤクルト本社 グラム陽性菌菌体表面へのタンパク質の固定化方法
WO1998025836A1 (en) 1996-12-11 1998-06-18 Lawson Mardon Wheaton Inc. Container closure with slide lock
EP1676920B1 (en) 1997-03-26 2014-07-09 Imperial Innovations Limited Anticoagulant fusion protein anchored to cell membrane
EP0916726A1 (en) * 1997-11-13 1999-05-19 Rijksuniversiteit te Groningen Attaching substances to micro-organisms
DE19800746A1 (de) 1998-01-12 1999-07-15 Muscholl Silberhorn Albrecht D Bakterielle Plasmidvektoren basierend auf alpha-Amylase mit breitem Wirtsspektrum und multiplen Anwendungen, unter besonderer Berücksichtigung Gram-positiver Bakterien
DE19903345A1 (de) 1999-01-28 2000-08-03 Werner Lubitz Kompartimentierung von rekombinanten Polypeptiden in Wirtszellen
DE19909770A1 (de) 1999-03-05 2000-09-07 Werner Lubitz Bakterienghosts als Träger- und Targetingvehikel
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
DE10003241A1 (de) 2000-01-26 2001-08-02 Werner Lubitz Verschließen von Bakterienghosts
US6827940B1 (en) 2000-05-25 2004-12-07 Aidan Products, Llc Immune-stimulating bacterial cell wall extracts
JP2002017357A (ja) 2000-07-04 2002-01-22 Calpis Co Ltd アンカーペプチド、融合蛋白質、及び蛋白質の固定化方法
ATE429484T1 (de) * 2001-06-11 2009-05-15 Applied Nanosystems Bv Verfahren zur bindung von acma-typ protein anker fusionen an mikroorganismen zellwandmaterialien
EP1634948A1 (en) * 2004-09-10 2006-03-15 Basf Aktiengesellschaft Means and methods for preventing and/or treating caries
JP2008269669A (ja) * 2007-04-17 2008-11-06 Renesas Technology Corp 半導体装置及びデータ処理システム

Also Published As

Publication number Publication date
DE60232071D1 (de) 2009-06-04
US20090239264A1 (en) 2009-09-24
WO2002101026A3 (en) 2003-08-28
ATE429484T1 (de) 2009-05-15
US20060115491A1 (en) 2006-06-01
WO2002101026A8 (en) 2004-03-11
CA2450318C (en) 2011-08-02
US7858357B2 (en) 2010-12-28
AU2002314626B2 (en) 2008-01-03
CN1541263A (zh) 2004-10-27
US6896887B2 (en) 2005-05-24
NZ530527A (en) 2006-06-30
CA2450318A1 (en) 2002-12-19
EP1395648B1 (en) 2009-04-22
WO2002101026A2 (en) 2002-12-19
CN100513548C (zh) 2009-07-15
EP1395648A2 (en) 2004-03-10
US7541039B2 (en) 2009-06-02
US20030186851A1 (en) 2003-10-02
US7067639B2 (en) 2006-06-27
US20030180816A1 (en) 2003-09-25

Similar Documents

Publication Publication Date Title
DK1395648T3 (da) Fremgangsmåder til binding af AcmA-type proteinankerfusioner til cellevægsmateriale af mikroorganismer
WO2004069211A3 (en) Affinity proteins for controlled application of cosmetic substances
DK1791860T3 (da) Oprensningsfremgangsmåde for bakterielt cytolysin
BRPI0513135A (pt) bibliotecas de polinucleotìdeos, método de produção das mesmas, método de identificação de um polinucleotìdeo, região de ligação, meio adequado para uso em um, dispositivo eletrÈnico e dispositivo
ATE551352T1 (de) Peptidakzeptorbindungsverfahren
WO2009073175A3 (en) Systems and methods for water treatment
DE60033555D1 (de) Verfahren und zusammestellungen zum nachweis und behandlung von brustkrebs, beruhend auf brustkrebs-assoziierten polypeptiden
ATE398676T2 (de) Antagonistische selektive bindungsagenzien des osteoprotegerin-bindungsproteins
DE50206471D1 (de) Verfahren zum abtrennen von hemicellulosen aus hemicellulosehaltiger biomasse
WO2005044367A3 (en) Method and apparatus for cell permeabilization
WO2003075953A3 (en) Immunomodulatory polymeric antigens for treating inflammatory pathogies
DE60129137D1 (de) Modulierung durch il-tif/interleukin-21
DE69719497D1 (de) Verfahren zur proteinaufreinigung aus einer proteinhaltigen lösung
DK0526546T3 (da) Additivsystemer i fast form, som er dispergerbare i vandige medier, fremgangsmåde til deres fremstilling og deres anvendelse på polymerpartikler
SG90769A1 (en) Method for crosslinking of isoprene-isobutylene rubber, ethylene-propylene-diene rubber containing ethylidenenorbornene as unsaturated component, or mixture thereof; and crosslinked rubber product obtained by said method
ATE272436T1 (de) Mikrofiltration unter verwendung von aktivkohle
ATE303436T1 (de) Verfahren zur langzeitlagerung von dns-molekülen, und verpackung zur durchführung dieses verfahrens
DE60234811D1 (de) Verfahren und zusammensetzungen zur extraktion von proteinen aus zellen
DE69927593D1 (de) Verfahren zur abtrennung von hydroxymethylthiobuttersäure
WO2005017237A3 (en) Apparatus and method for the selective assembly of protein
MXPA01009272A (es) Procedimiento de deformacion permanente de materias queratinicas que utiliza un agente absorbente organico.
WO2004079332A3 (en) Composition and method for increasing efficiency of introduction of target substance into cell
PE83299A1 (es) Proceso para preparar haluros de acido o-(3-amino-2-hidroxi-propil)-hidroximico
DE69905772T2 (de) Verfahren zur rückgewinnung von 3,4-epoxy-1-buten
WO2004004455A3 (de) Zusammensetzung und verfahren zur stabilisierung von biomolekülen