ATE296877T1 - Enzyme zur spaltung der verankerungsregion von oberflächenproteinen aus gram-positiven bakterien - Google Patents

Enzyme zur spaltung der verankerungsregion von oberflächenproteinen aus gram-positiven bakterien

Info

Publication number
ATE296877T1
ATE296877T1 AT95936209T AT95936209T ATE296877T1 AT E296877 T1 ATE296877 T1 AT E296877T1 AT 95936209 T AT95936209 T AT 95936209T AT 95936209 T AT95936209 T AT 95936209T AT E296877 T1 ATE296877 T1 AT E296877T1
Authority
AT
Austria
Prior art keywords
gram
positive bacteria
surface proteins
enzyme
cliving
Prior art date
Application number
AT95936209T
Other languages
English (en)
Inventor
Vincent A Fischetti
Vijaykumar Pancholi
Original Assignee
Univ Rockefeller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rockefeller filed Critical Univ Rockefeller
Application granted granted Critical
Publication of ATE296877T1 publication Critical patent/ATE296877T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
AT95936209T 1994-10-07 1995-10-06 Enzyme zur spaltung der verankerungsregion von oberflächenproteinen aus gram-positiven bakterien ATE296877T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31954094A 1994-10-07 1994-10-07
PCT/US1995/012460 WO1996011263A1 (en) 1994-10-07 1995-10-06 Enzyme for cleavage of the anchor region of surface proteins from gram positive bacteria

Publications (1)

Publication Number Publication Date
ATE296877T1 true ATE296877T1 (de) 2005-06-15

Family

ID=23242676

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95936209T ATE296877T1 (de) 1994-10-07 1995-10-06 Enzyme zur spaltung der verankerungsregion von oberflächenproteinen aus gram-positiven bakterien

Country Status (10)

Country Link
US (1) US5968763A (de)
EP (1) EP0804559B1 (de)
JP (1) JPH10506795A (de)
AT (1) ATE296877T1 (de)
AU (1) AU697227B2 (de)
CA (1) CA2201616A1 (de)
DE (1) DE69534252T2 (de)
ES (1) ES2240979T3 (de)
PT (1) PT804559E (de)
WO (1) WO1996011263A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6737521B1 (en) * 1990-05-11 2004-05-18 The Rockefeller University Delivery and expression of a hybrid surface protein on the surface of gram positive bacteria
US6056954A (en) 1997-10-31 2000-05-02 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses
US6432444B1 (en) 1997-10-31 2002-08-13 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymes for treating dermatological infections
US7232576B2 (en) 1997-10-31 2007-06-19 New Horizons Diagnostics Corp Throat lozenge for the treatment of Streptococcus Group A
US6277399B1 (en) 1997-10-31 2001-08-21 New Horizon Diagnostics Corporation Composition incorporating bacterial phage associated lysing enzymes for treating dermatological infections
US6752988B1 (en) * 2000-04-28 2004-06-22 New Horizons Diagnostic Corp Method of treating upper resiratory illnesses
US6423299B1 (en) 1997-10-31 2002-07-23 Vincent Fischetti Composition for treatment of a bacterial infection of an upper respiratory tract
US6428784B1 (en) * 1997-10-31 2002-08-06 New Horizons Diagnostics Corp Vaginal suppository for treating group B Streptococcus infection
US20030082110A1 (en) * 1997-10-31 2003-05-01 Vincent Fischetti Use of bacterial phage associated lysing proteins for treating bacterial dental caries
US6406692B1 (en) 1997-10-31 2002-06-18 New Horizons Diagnostics Corp Composition for treatment of an ocular bacterial infection
US20030129146A1 (en) * 1997-10-31 2003-07-10 Vincent Fischetti The use of bacterial phage associated lysing proteins for treating bacterial dental caries
US7063837B2 (en) * 1999-09-14 2006-06-20 New Horizons Diagnostics Corp Syrup composition containing phage associated lytic enzymes
US7939087B2 (en) 2000-10-27 2011-05-10 Novartis Vaccines And Diagnostics, Inc. Nucleic acids and proteins from Streptococcus groups A & B
WO2002101026A2 (en) 2001-06-11 2002-12-19 Applied Nanosystems B.V. Methods for binding acma-type protein anchor fusions to cell-wall material of micro-organisms
AU2003260102A1 (en) * 2002-08-26 2004-03-11 Chiron Corporation Conserved and specific streptococcal genomes
US7604975B2 (en) * 2002-10-01 2009-10-20 The Rockefeller University Glycosylated LPXTGases and uses thereof
PT1648500E (pt) * 2003-07-31 2014-10-10 Novartis Vaccines & Diagnostic Composições imunogénicas para estreptococos piogenes
US8945589B2 (en) * 2003-09-15 2015-02-03 Novartis Vaccines And Diagnostics, Srl Immunogenic compositions for Streptococcus agalactiae
CA2575548A1 (en) 2004-07-29 2006-07-27 John L. Telford Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae
EP1807446A2 (de) * 2004-10-08 2007-07-18 Novartis Vaccines and Diagnostics, Inc. Immunogene und therapeutische zusammensetzungen für pyogene streptokokken
JP2010508276A (ja) * 2006-10-30 2010-03-18 ノバルティス アーゲー 化膿連鎖球菌のための免疫原性組成物および治療組成物
BRPI0816689B1 (pt) 2007-09-12 2021-08-24 Novartis Ag Composição de vacina, kit e método para a confecção de uma composição de vacina para a prevenção ou tratamento de infecção por streptococcus pyogenes
CA2709927C (en) 2007-12-21 2017-05-16 Novartis Ag Mutant forms of streptolysin o

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0116454B1 (de) * 1983-02-11 1987-04-29 National Research Development Corporation Erhöhte lumineszierende oder luminometrische Prüfung
US5235039A (en) * 1991-06-10 1993-08-10 Eli Lilly And Company Substrates for hiv protease

Also Published As

Publication number Publication date
AU3824095A (en) 1996-05-02
PT804559E (pt) 2005-08-31
WO1996011263A1 (en) 1996-04-18
CA2201616A1 (en) 1996-04-18
DE69534252D1 (de) 2005-07-07
EP0804559B1 (de) 2005-06-01
ES2240979T3 (es) 2005-10-16
EP0804559A1 (de) 1997-11-05
DE69534252T2 (de) 2005-10-27
US5968763A (en) 1999-10-19
EP0804559A4 (de) 2000-05-31
JPH10506795A (ja) 1998-07-07
AU697227B2 (en) 1998-10-01

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