HUE044211T2 - Staphylococcus aureus elleni immunizálásra szolgáló, stabilizált fehérjék - Google Patents

Staphylococcus aureus elleni immunizálásra szolgáló, stabilizált fehérjék

Info

Publication number
HUE044211T2
HUE044211T2 HUE13753327A HUE044211T2 HU E044211 T2 HUE044211 T2 HU E044211T2 HU E13753327 A HUE13753327 A HU E13753327A HU E044211 T2 HUE044211 T2 HU E044211T2
Authority
HU
Hungary
Prior art keywords
staphylococcus aureus
against staphylococcus
immunising against
stabilised
proteins
Prior art date
Application number
Other languages
English (en)
Inventor
Fabio Bagnoli
Fabiana Falugi
Guido Grandi
Massimo Mariani
Mikkel Nissum
Michele Pallaoro
Silvana Savino
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of HUE044211T2 publication Critical patent/HUE044211T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/085Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
HUE13753327 2012-08-31 2013-08-29 Staphylococcus aureus elleni immunizálásra szolgáló, stabilizált fehérjék HUE044211T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261695723P 2012-08-31 2012-08-31

Publications (1)

Publication Number Publication Date
HUE044211T2 true HUE044211T2 (hu) 2019-10-28

Family

ID=49036594

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE13753327 HUE044211T2 (hu) 2012-08-31 2013-08-29 Staphylococcus aureus elleni immunizálásra szolgáló, stabilizált fehérjék

Country Status (15)

Country Link
US (1) US9926344B2 (hu)
EP (1) EP2890394B1 (hu)
JP (1) JP6435261B2 (hu)
CN (2) CN110563818A (hu)
CY (1) CY1121944T1 (hu)
DK (1) DK2890394T3 (hu)
ES (1) ES2737024T3 (hu)
HR (1) HRP20191166T1 (hu)
HU (1) HUE044211T2 (hu)
LT (1) LT2890394T (hu)
PL (1) PL2890394T3 (hu)
PT (1) PT2890394T (hu)
SI (1) SI2890394T1 (hu)
TR (1) TR201910573T4 (hu)
WO (1) WO2014033190A1 (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2014CN02152A (hu) * 2011-09-01 2015-09-04 Novartis Ag
EA037818B1 (ru) 2014-03-26 2021-05-25 Глаксосмитклайн Байолоджикалс С.А. Мутантные стафилококковые антигены
EP3538266B1 (en) 2016-11-14 2024-08-21 Lilac Solutions, Inc. Lithium extraction with coated ion exchange particles
JP6916042B2 (ja) * 2017-06-09 2021-08-11 株式会社明治 抗原特異的インターフェロンγ産生促進用組成物
AR112663A1 (es) 2017-08-02 2019-11-27 Lilac Solutions Inc Extracción de litio con perlas porosas de intercambio iónico
JP7427598B2 (ja) 2018-02-28 2024-02-05 ライラック ソリューションズ,インク. リチウム抽出用の粒子トラップを備えたイオン交換反応器
EP4087825A4 (en) 2020-01-09 2024-01-24 Lilac Solutions, Inc. PROCESS FOR SEPARATING UNWANTED METALS
CN111595658B (zh) * 2020-06-06 2023-11-14 宾傲 一种提取细胞中蛋白的裂解液及其制备方法
JP2023529444A (ja) 2020-06-09 2023-07-10 ライラック ソリューションズ,インク. スケール物質存在下におけるリチウム抽出
EP4247759A1 (en) 2020-11-20 2023-09-27 Lilac Solutions, Inc. Lithium production with volatile acid
EP4326413A1 (en) 2021-04-23 2024-02-28 Lilac Solutions, Inc. Ion exchange devices for lithium extraction
WO2023192192A1 (en) 2022-03-28 2023-10-05 Lilac Solutions, Inc. Lithium extraction enhanced by an alternate phase

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS624300A (ja) * 1985-06-28 1987-01-10 Dai Ichi Seiyaku Co Ltd 改良型ヒトガンマインタ−フエロンおよびその製造方法
DE68929273T2 (de) * 1988-08-24 2001-07-05 American Cyanamid Co., Wayne Stabilisierung von Somatotropinen durch Modifikation von Cystein-Resten durch orts-spezifische Mutagenese oder chemische Derivatisierung
HU212924B (en) 1989-05-25 1996-12-30 Chiron Corp Adjuvant formulation comprising a submicron oil droplet emulsion
US5874238A (en) 1993-02-26 1999-02-23 Immtech International Inc. Mutant protein and methods and materials for making and using it
AU5543294A (en) 1993-10-29 1995-05-22 Pharmos Corp. Submicron emulsions as vaccine adjuvants
US6080725A (en) 1997-05-20 2000-06-27 Galenica Pharmaceuticals, Inc. Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof
ATE375803T1 (de) 1998-05-07 2007-11-15 Corixa Corp Adjuvanszusammensetzung und methoden zu deren verwendng
CA2773698C (en) 1998-10-16 2015-05-19 Glaxosmithkline Biologicals S.A. Adjuvant systems comprising an immunostimulant adsorbed to a metallic salt particle and vaccines thereof
GB9825421D0 (en) * 1998-11-19 1999-01-13 Isis Innovation Process for oxidising terpenes
CA2361421A1 (en) 1999-02-03 2000-08-10 Biosante Pharmaceuticals, Inc. Therapeutic calcium phosphate particles and methods of manufacture and use
KR100382239B1 (ko) * 2000-02-17 2003-04-26 주식회사 엘지생명과학 황색 포도상 구균의 변이 독소 에스이씨-에스이알, 그것의발현벡터 및 숙주세포, 그 생산방법 및 백신제조방법
IL152804A0 (en) * 2000-05-16 2003-06-24 Bolder Biotechnology Inc Methods for refolding proteins containing free cysteine residues
GB0107661D0 (en) * 2001-03-27 2001-05-16 Chiron Spa Staphylococcus aureus
KR20090051129A (ko) 2004-04-05 2009-05-20 화이자 프로덕츠 인코포레이티드 미세유체화된 수중유 유화액 및 백신 조성물
US20060228369A1 (en) 2005-04-11 2006-10-12 Program For Appropriate Technology In Health Stabilization and preservation of temperature-sensitive vaccines
US7691368B2 (en) 2005-04-15 2010-04-06 Merial Limited Vaccine formulations
US8703095B2 (en) 2005-07-07 2014-04-22 Sanofi Pasteur S.A. Immuno-adjuvant emulsion
US20090269358A1 (en) * 2005-10-07 2009-10-29 Shone Clifford C Proteins with Improved Solubility and Methods for Producing and Using Same
FR2896162B1 (fr) 2006-01-13 2008-02-15 Sanofi Pasteur Sa Emulsion huile dans eau thermoreversible
CA2637598A1 (en) 2006-01-18 2007-02-14 University Of Chicago Compositions and methods related to staphylococcal bacterium proteins
PT2086582E (pt) 2006-10-12 2013-01-25 Glaxosmithkline Biolog Sa Vacina compreendendo uma emulsão adjuvante óleo em água
UY31930A (es) * 2008-06-25 2010-01-29 Boheringer Ingelheim Pharma Kg Pestivirus atenuados recombinantes, en particular a csfv, bvdv o bdv atenuado recombinante
SG175092A1 (en) 2009-04-14 2011-11-28 Novartis Ag Compositions for immunising against staphylococcus aerus
CN102844047B (zh) 2009-09-02 2017-04-05 诺华股份有限公司 含tlr活性调节剂的免疫原性组合物
JP2013506651A (ja) * 2009-09-30 2013-02-28 ノバルティス アーゲー Staphylococcus.aureus5型および8型莢膜多糖の結合体
PT2493498T (pt) 2009-10-30 2017-05-24 Glaxosmithkline Biologicals Sa Purificação de sacáridos capsulares de staphylococcus aureus tipo 5 e tipo 8
JP2011212008A (ja) * 2010-03-16 2011-10-27 Olympus Corp 蛍光タンパク質およびpH測定方法
IN2014CN02152A (hu) * 2011-09-01 2015-09-04 Novartis Ag
JP2015500864A (ja) 2011-12-23 2015-01-08 ノバルティス アーゲー 黄色ブドウ球菌(Staphylococcusaureus)に対して免疫するための安定な組成物

Also Published As

Publication number Publication date
US9926344B2 (en) 2018-03-27
PL2890394T3 (pl) 2019-12-31
SI2890394T1 (sl) 2019-06-28
CN110563818A (zh) 2019-12-13
EP2890394B1 (en) 2019-05-01
ES2737024T3 (es) 2020-01-09
CY1121944T1 (el) 2020-10-14
HRP20191166T1 (hr) 2019-10-04
EP2890394A1 (en) 2015-07-08
JP6435261B2 (ja) 2018-12-05
US20150203542A1 (en) 2015-07-23
PT2890394T (pt) 2019-07-15
DK2890394T3 (da) 2019-07-15
CN104619336A (zh) 2015-05-13
WO2014033190A1 (en) 2014-03-06
LT2890394T (lt) 2019-07-25
TR201910573T4 (tr) 2019-08-21
JP2015528455A (ja) 2015-09-28

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