JP5850547B2 - 胸部外科手術用の移植材料 - Google Patents
胸部外科手術用の移植材料 Download PDFInfo
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- JP5850547B2 JP5850547B2 JP2014168212A JP2014168212A JP5850547B2 JP 5850547 B2 JP5850547 B2 JP 5850547B2 JP 2014168212 A JP2014168212 A JP 2014168212A JP 2014168212 A JP2014168212 A JP 2014168212A JP 5850547 B2 JP5850547 B2 JP 5850547B2
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- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3695—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the function or physical properties of the final product, where no specific conditions are defined to achieve this
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- A—HUMAN NECESSITIES
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
- A61F2002/0068—Implantable repair or support meshes, e.g. hernia meshes having a special mesh pattern
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- A—HUMAN NECESSITIES
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0004—Rounded shapes, e.g. with rounded corners
- A61F2230/0008—Rounded shapes, e.g. with rounded corners elliptical or oval
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
- A61F2240/002—Designing or making customized prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/04—Materials or treatment for tissue regeneration for mammary reconstruction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3637—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the origin of the biological material other than human or animal, e.g. plant extracts, algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49995—Shaping one-piece blank by removing material
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Description
Claims (49)
- 胸部外科手術用の医療デバイスであって、
生体適合性材料のサンプル(13)を備え、この生体適合性材料のサンプルが、第1エッジ(15)および第2エッジ(17)を含み、前記第1エッジ(15)が、前記第2エッジ(17)から離れるように湾曲する凸状部を有し、前記第2エッジ(17)が、前記第1エッジ(15)から離れるように湾曲する凸状部を有し、
前記第1エッジ(15)および前記第2エッジ(17)が、先の尖った頂部(19)で結合し、
前記生体適合性材料のサンプル(13)が、垂直軸(x)に関して対称であることを特徴とする医療デバイス。 - 請求項1に記載の医療デバイスにおいて、
前記生体適合性材料のサンプル(13)が、両凸の形状であることを特徴とする医療デバイス。 - 請求項1に記載の医療デバイスにおいて、
前記第1エッジ(15)が、実質的に放物線状に湾曲していることを特徴とする医療デバイス。 - 請求項1に記載の医療デバイスにおいて、
前記第2エッジ(17)が、実質的に放物線状に湾曲していることを特徴とする医療デバイス。 - 請求項1に記載の医療デバイスにおいて、
前記第1エッジ(15)が、非凸状の部分(29)を含むことを特徴とする医療デバイス。 - 請求項1に記載の医療デバイスにおいて、
前記第2エッジ(17)が、非凸状の部分(31)を含むことを特徴とする医療デバイス。 - 請求項1に記載の医療デバイスにおいて、
前記第2エッジ(17)が、実質的に直線状の部分を含むことを特徴とする医療デバイス。 - 請求項1に記載の医療デバイスにおいて、
前記第2エッジ(17)が、凹状の部分を含むことを特徴とする医療デバイス。 - 請求項1に記載の医療デバイスにおいて、
前記生体適合性材料のサンプル(13)が、縦軸(y)に関して非対称であることを特徴とする医療デバイス。 - 請求項1に記載の医療デバイスにおいて、
前記第1エッジ(15)が第1頂点を含み、前記第2エッジ(17)が第2頂点を含み、
前記第1エッジ(15)の前記第1頂点が、前記第1エッジ(15)の第1焦点から第1長さ離れており、前記第2エッジ(17)の前記第2頂点が、前記第2エッジ(17)の第2焦点から第2長さ離れており、前記第2長さが前記第1長さよりも大きいことを特徴とする医療デバイス。 - 請求項1に記載の医療デバイスにおいて、
前記生体適合性材料のサンプル(13)が、無細胞組織マトリクスを含むことを特徴とする医療デバイス。 - 請求項11に記載の医療デバイスにおいて、
前記無細胞組織マトリクスが、ヒト以外の動物からの脱細胞化コラーゲン含有組織マトリクスを含むことを特徴とする医療デバイス。 - 請求項11に記載の医療デバイスにおいて、
前記無細胞組織マトリクスが、上皮基底膜を全くまたは実質的に有していないことを特徴とする医療デバイス。 - 請求項11に記載の医療デバイスにおいて、
前記無細胞組織マトリクスが、真皮組織マトリクスであることを特徴とする医療デバイス。 - 請求項12に記載の医療デバイスにおいて、
前記ヒト以外の動物がブタであることを特徴とする医療デバイス。 - 請求項12に記載の医療デバイスにおいて、
前記ヒト以外の動物内の組織がガラクトースα−1,3−ガラクトースエピトープを全くまたは実質的に持たないように、前記ヒト以外の動物が遺伝子操作されていることを特徴とする医療デバイス。 - 胸部外科手術用の医療デバイスであって、
生体適合性材料のシート(13)を備え、この生体適合性材料のシートが、第1エッジ(15)および第2エッジ(17)を含み、前記第1エッジ(15)が、前記第2エッジ(17)から離れるように湾曲する凸状部を有し、前記第2エッジ(17)が、前記第1エッジ(15)から離れるように湾曲する凸状部を有し、
前記第1エッジ(15)が第1頂点を含み、前記第2エッジ(17)が第2頂点を含み、
前記第1エッジ(15)の前記第1頂点が、前記第1エッジ(15)の第1焦点から第1長さ離れており、前記第2エッジ(17)の前記第2頂点が、前記第2エッジ(17)の第2焦点から第2長さ離れており、前記第2長さが前記第1長さよりも大きく、
前記生体適合性材料のシート(13)が、垂直軸(x)に関して対称であることを特徴とする医療デバイス。 - 請求項17に記載の医療デバイスにおいて、
前記生体適合性材料のシート(13)が、当該生体適合性材料のシート(13)と一致する縦軸(y)を含み、前記垂直軸(x)が、前記第1および第2頂点を通り、前記生体適合性材料のシート(13)の前記縦軸(y)に沿う長さが、前記生体適合性材料のサシート(13)の前記垂直軸(x)に沿う長さよりも長いことを特徴とする医療デバイス。 - 胸部外科手術用の医療デバイスであって、
生体適合性材料のサンプル(13)を備え、この生体適合性材料のサンプルが、第1エッジ(15)および第2エッジ(17)を含み、前記第1エッジ(15)が、前記第2エッジ(17)から離れるように湾曲する凸状部を有し、前記第2エッジ(17)が、前記第1エッジ(15)から離れるように湾曲する凸状部を有し、
前記第1エッジ(15)および前記第2エッジ(17)が、先の尖った頂部(19)で結合し、
前記生体適合性材料のサンプル(13)が、垂直軸(x)に関して対称であり、
前記生体適合性材料のサンプル(13)が、当該生体適合性材料のサンプル(13)の少なくとも一部を横切るミシン目のセット(23)を含むことを特徴とする医療デバイス。 - 請求項19に記載の医療デバイスにおいて、
前記ミシン目のセット(23)が、弓形のパターンを形成することを特徴とする医療デバイス。 - 請求項19に記載の医療デバイスにおいて、
前記ミシン目のセット(23)が、半円のパターンで配列されていることを特徴とする医療デバイス。 - 請求項19に記載の医療デバイスにおいて、
前記ミシン目のセット(23)が、メッシュ状のパターンを形成することを特徴とする医療デバイス。 - 請求項19に記載の医療デバイスにおいて、
前記ミシン目のセット(23)が、一連の平行なスリット(25)を備え、前記スリットがほぼ均一な長さを有し、ほぼ均一な間隙距離で、隣接するスリットが長手方向に分離され、ほぼ均一な水平隔離距離で、隣接する平行なスリット(25)が分離されることを特徴とする医療デバイス。 - 請求項23に記載の医療デバイスにおいて、
前記長さが、0.1mmと20mmの間であることを特徴とする医療デバイス。 - 請求項23に記載の医療デバイスにおいて、
前記長さが、4mmと8mmの間であることを特徴とする医療デバイス。 - 請求項23に記載の医療デバイスにおいて、
前記間隙距離が、0.1mmと20mmの間であることを特徴とする医療デバイス。 - 請求項23に記載の医療デバイスにおいて、
前記間隙距離が、2mmと6mmの間であることを特徴とする医療デバイス。 - 請求項23に記載の医療デバイスにおいて、
前記水平隔離距離が、0.1mmと20mmの間であることを特徴とする医療デバイス。 - 請求項23に記載の医療デバイスにおいて、
前記水平隔離距離が、2mmと6mmの間であることを特徴とする医療デバイス。 - 請求項23に記載の医療デバイスにおいて、
隣接する平行なスリット(25)が、長手方向に互いにオフセットされていることを特徴とする医療デバイス。 - 請求項19に記載の医療デバイスにおいて、
個々のミシン目(23)が、弓形であることを特徴とする医療デバイス。 - 請求項19に記載の医療デバイスにおいて、
前記生体適合性材料のサンプル(13)が、無細胞組織マトリクスを含むことを特徴とする医療デバイス。 - 請求項32に記載の医療デバイスにおいて、
前記無細胞組織マトリクスが、ヒト以外の動物からの脱細胞化コラーゲン含有組織マトリクスを含むことを特徴とする医療デバイス。 - 請求項32に記載の医療デバイスにおいて、
前記無細胞組織マトリクスが、上皮基底膜を全くまたは実質的に持たないことを特徴とする医療デバイス。 - 請求項32に記載の医療デバイスにおいて、
前記無細胞組織マトリクスが、真皮組織マトリクスであることを特徴とする医療デバイス。 - 請求項33に記載の医療デバイスにおいて、
前記ヒト以外の動物がブタであることを特徴とする医療デバイス。 - 請求項33に記載の医療デバイスにおいて、
前記ヒト以外の動物内の組織がガラクトースα−1,3−ガラクトースエピトープを全くまたは実質的に持たないように、前記ヒト以外の動物が遺伝子操作されていることを特徴とする医療デバイス。 - 胸部外科手術用の医療デバイスであって、
生体適合性材料のサンプル(13)を備え、この生体適合性材料のサンプルが、第1エッジ(15)および第2エッジ(17)を含み、前記第1エッジ(15)が、前記第2エッジ(17)から離れるように湾曲する凸状部を有し、前記第2エッジ(17)が、前記第1エッジ(15)から離れるように湾曲する凸状部を有し、
前記第1エッジ(15)および前記第2エッジ(17)が、先の尖った頂部(19)で結合し、
前記生体適合性材料のサンプル(13)が、垂直軸(x)に関して対称であり、
前記生体適合性材料のサンプル(13)が、予め設定された体積を有する胸部インプラント(21)の表面の一部に合うようなサイズおよび形状とされることを特徴とする医療デバイス。 - 請求項38に記載の医療デバイスにおいて、
前記胸部インプラント(21)が、丸みを帯びたインプラントであることを特徴とする医療デバイス。 - 請求項38に記載の医療デバイスにおいて、
前記胸部インプラント(21)が、解剖学的インプラントであることを特徴とする医療デバイス。 - 請求項38に記載の医療デバイスにおいて、
前記胸部インプラント(21)の予め設定された体積が、400ccと550ccの間であることを特徴とする医療デバイス。 - 請求項38に記載の医療デバイスにおいて、
前記胸部インプラント(21)の予め設定された体積が、250ccと400ccの間であることを特徴とする医療デバイス。 - 請求項38に記載の医療デバイスにおいて、
前記胸部インプラント(21)の予め設定された体積が、100ccと250ccの間であることを特徴とする医療デバイス。 - 1またはそれ以上の移植デバイスの製造方法であって、
生体適合性材料(13)のシートを提供するステップと、
前記生体適合性材料(13)のシートから1またはそれ以上のサンプルを切断するステップとを備え、
前記1またはそれ以上のサンプルが、第1エッジ(15)および第2エッジ(17)を含み、前記第1エッジ(15)が、前記第2エッジ(17)から離れるように湾曲する凸状部を有し、前記第2エッジ(17)が、前記第1エッジ(15)から離れるように湾曲する凸状部を有し、
前記第1エッジ(15)および前記第2エッジ(17)が、先の尖った頂部(19)で結合し、
前記生体適合性材料(13)のサンプルが、垂直軸(x)に関して対称であることを特徴とする方法。 - 請求項44に記載の方法において、
前記1またはそれ以上のサンプルを切断するステップが、生体適合性材料(13)に第1エッジ(15)および第2エッジ(17)を形成するステップであって、前記第1エッジ(15)が、凸状部を含み、かつ前記第2エッジ(17)が、凸状部を含むように、前記第1エッジおよび前記第2エッジを形成するステップを備えることを特徴とする方法。 - 請求項44に記載の方法において、
前記1またはそれ以上のサンプルにミシン目のセット(23)を形成するステップをさらに備え、前記ミシン目のセット(23)が、前記1またはそれ以上のサンプルの少なくとも一部を横切る弓形のパターンを形成することを特徴とする方法。 - 1またはそれ以上の移植デバイスの製造方法であって、
生体適合性材料(13)のシートを提供するステップと、
前記生体適合性材料(13)のシートから1またはそれ以上のサンプルを切断するステップとを備え、
前記1またはそれ以上のサンプルが、第1エッジ(15)および第2エッジ(17)を含み、前記第1エッジ(15)が、前記第2エッジ(17)から離れるように湾曲する凸状部を有し、前記第2エッジ(17)が、前記第1エッジ(15)から離れるように湾曲する凸状部を有し、
前記第1エッジ(15)が第1頂点を含み、前記第2エッジ(17)が第2頂点を含み、
前記第1エッジ(15)の前記第1頂点が、前記第1エッジ(15)の第1焦点から第1長さ離れており、前記第2エッジ(17)の前記第2頂点が、前記第2エッジ(17)の第2焦点から第2長さ離れており、前記第2長さが前記第1長さよりも大きく、
前記1またはそれ以上のサンプルが、垂直軸(x)に関して対称であることを特徴とする方法。 - 1またはそれ以上の移植デバイスの製造方法であって、
生体適合性材料(13)のシートを提供するステップと、
前記生体適合性材料(13)のシートから1またはそれ以上のサンプルを切断するステップとを備え、
前記1またはそれ以上のサンプルが、第1エッジ(15)および第2エッジ(17)を含み、前記第1エッジ(15)が、前記第2エッジ(17)から離れるように湾曲する凸状部を有し、前記第2エッジ(17)が、前記第1エッジ(15)から離れるように湾曲する凸状部を有し、
前記第1エッジ(15)および前記第2エッジ(17)が、先の尖った頂部(19)で結合し、
前記1またはそれ以上のサンプルが、垂直軸(x)に関して対称であり、
前記1またはそれ以上のサンプルが、前記生体適合性材料(13)のサンプルの少なくとも一部を横切るミシン目のセット(23)を含むことを特徴とする方法。 - 1またはそれ以上の移植デバイスの製造方法であって、
生体適合性材料(13)のシートを提供するステップと、
前記生体適合性材料(13)のシートから1またはそれ以上のサンプルを切断するステップとを備え、
前記1またはそれ以上のサンプルが、第1エッジ(15)および第2エッジ(17)を含み、前記第1エッジ(15)が、前記第2エッジ(17)から離れるように湾曲する凸状部を有し、前記第2エッジ(17)が、前記第1エッジ(15)から離れるように湾曲する凸状部を有し、
前記第1エッジ(15)および前記第2エッジ(17)が、先の尖った頂部(19)で結合し、
前記1またはそれ以上のサンプルが、垂直軸(x)に関して対称であり、
前記1またはそれ以上のサンプルが、予め設定された体積を有する胸部インプラント(21)の表面の一部に合うようなサイズおよび形状とされることを特徴とする方法。
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Families Citing this family (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6902932B2 (en) * | 2001-11-16 | 2005-06-07 | Tissue Regeneration, Inc. | Helically organized silk fibroin fiber bundles for matrices in tissue engineering |
US20110009960A1 (en) * | 2001-11-16 | 2011-01-13 | Allergan, Inc. | Prosthetic fabric structure |
US7998152B2 (en) * | 2006-12-21 | 2011-08-16 | Frank Robert E | Implantable prosthesis for periareolar mastopexy |
US20100023029A1 (en) * | 2008-07-23 | 2010-01-28 | Bodyaesthetic Research Center, Inc. | Mesh Device for Immediate Breast Construction and Uses Thereof |
US9204953B2 (en) | 2008-12-15 | 2015-12-08 | Allergan, Inc. | Biocompatible surgical scaffold with varying stretch |
US9204954B2 (en) * | 2008-12-15 | 2015-12-08 | Allergan, Inc. | Knitted scaffold with diagonal yarn |
CA2745571C (en) | 2008-12-15 | 2015-03-24 | Allergan, Inc. | A prosthetic device and method of manufacturing the same |
US9326840B2 (en) | 2008-12-15 | 2016-05-03 | Allergan, Inc. | Prosthetic device and method of manufacturing the same |
US9308070B2 (en) * | 2008-12-15 | 2016-04-12 | Allergan, Inc. | Pliable silk medical device |
US8986377B2 (en) | 2009-07-21 | 2015-03-24 | Lifecell Corporation | Graft materials for surgical breast procedures |
NZ598691A (en) * | 2009-09-11 | 2014-05-30 | Allergan Inc | Prosthetic device and method of manufacturing the same |
CN103108661B (zh) * | 2010-03-25 | 2016-01-20 | 生命细胞公司 | 再生性组织支架的制备 |
US11246697B2 (en) | 2010-05-05 | 2022-02-15 | Markman Biologics Corporation | Method and apparatus for creating a reconstructive graft |
US8858647B2 (en) | 2010-05-05 | 2014-10-14 | Barry Markman | Method and apparatus for a process creating an internal tissue graft for animal and human reconstructive purposes |
US11701213B2 (en) | 2010-05-05 | 2023-07-18 | Markman Biologics Corporation | Method and apparatus for creating a modified tissue graft |
US9622845B2 (en) | 2010-05-05 | 2017-04-18 | Barry Markman | Method and apparatus for creating a reconstructive graft |
US11877921B2 (en) | 2010-05-05 | 2024-01-23 | Markman Biologics Corporation | Method and apparatus for creating a modified tissue graft |
CN103068413B (zh) | 2010-07-08 | 2015-12-16 | 生命细胞公司 | 用于使组织基质成形的方法 |
WO2012122215A2 (en) | 2011-03-09 | 2012-09-13 | Galatea Corporation | Systems and methods for mastopexy |
PL2556806T3 (pl) * | 2011-08-11 | 2016-09-30 | Wszczepialna proteza medyczna | |
ES2596522T3 (es) | 2012-01-13 | 2017-01-10 | Lifecell Corporation | Prótesis mamarias y métodos de fabricación de prótesis mamarias |
WO2013192197A1 (en) | 2012-06-21 | 2013-12-27 | Lifecell Corporation | Implantable prosthesis having acellular tissue attachments |
EP2903562A1 (en) * | 2012-10-04 | 2015-08-12 | Lifecell Corporation | Surgical template and delivery device |
EP2967835B1 (en) | 2013-03-14 | 2018-08-08 | Musculoskeletal Transplant Foundation | Soft tissue repair allografts and methods for preparing same |
KR102040592B1 (ko) * | 2013-03-18 | 2019-11-06 | 주식회사 엘앤씨바이오 | 생체 이식물 제조방법 |
EP3019206B1 (en) * | 2013-07-11 | 2019-12-04 | Tepha, Inc. | Absorbable implants for plastic surgery |
MX2016001247A (es) | 2013-07-30 | 2016-08-17 | Musculoskeletal Transplant Foundation | Matrices derivadas de tejido suave acelular y metodos para preparar las mismas. |
CN103393482B (zh) * | 2013-08-14 | 2016-04-06 | 北京瑞健高科生物科技有限公司 | 一种基于组织基质材料的乳房假体支撑装置及其制备方法 |
US10898312B2 (en) * | 2013-10-28 | 2021-01-26 | The Regents Of The University Of California | Tissue grafts with fenestrations |
DE102014011034B4 (de) * | 2014-07-23 | 2016-06-23 | Uniprox GmbH & Co. KG | Perforierter Liner |
USD803401S1 (en) * | 2015-04-23 | 2017-11-21 | Tepha, Inc. | Three dimensional mastopexy implant |
US10307237B2 (en) * | 2015-05-15 | 2019-06-04 | Lifecell Corporation | Tissue matrices and methods of treatment |
US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
WO2017034952A1 (en) * | 2015-08-21 | 2017-03-02 | Lifecell Corporation | Breast treatment device |
AU2016318967B2 (en) | 2015-09-11 | 2021-05-27 | Lifecell Corporation | Perforated tissue matrix |
USD836778S1 (en) | 2015-10-09 | 2018-12-25 | Tepha, Inc. | Three dimensional mastopexy implant |
CA2970965C (en) * | 2015-10-16 | 2019-06-18 | Lifenet Health | Soft tissue grafts, and methods of making and using same |
GB201521474D0 (en) | 2015-12-04 | 2016-01-20 | Univ Manchester | Textured surfaces for implants |
EP3386436A4 (en) * | 2015-12-10 | 2019-08-21 | Novothelium, LLC | EXTRACELLULAR MATRIX EQUIPMENT OF THE AREOLARY COMPLEX OF A HUMAN MAMILY AND RELATED METHODS |
CN105435308B (zh) * | 2015-12-23 | 2018-10-26 | 天津幂方科技有限公司 | 一种乳房植入体三维结构及其快速成形方法 |
US11523812B2 (en) | 2016-02-01 | 2022-12-13 | Medos International Sarl | Soft tissue fixation repair methods using tissue augmentation constructs |
US11484401B2 (en) | 2016-02-01 | 2022-11-01 | Medos International Sarl | Tissue augmentation scaffolds for use in soft tissue fixation repair |
ITUB20161141A1 (it) * | 2016-02-08 | 2017-08-08 | Deco Med S R L | Dispositivo medico, particolarmente per il trattamento e la prevenzione della fibrosi capsulare nella chirurgia della mammella |
JP2019504708A (ja) | 2016-02-11 | 2019-02-21 | ライフセル コーポレーションLifeCell Corporation | 酵素分解に対するコラーゲン含有組織製品の安定化方法 |
USD856517S1 (en) | 2016-06-03 | 2019-08-13 | Musculoskeletal Transplant Foundation | Asymmetric tissue graft |
US10945831B2 (en) * | 2016-06-03 | 2021-03-16 | Musculoskeletal Transplant Foundation | Asymmetric tissue graft |
WO2018009428A1 (en) * | 2016-07-05 | 2018-01-11 | Lifecell Corporation | Tissue matrices incorporating multiple tissue types |
EP3506854B1 (en) * | 2016-08-31 | 2020-08-19 | LifeCell Corporation | Breast treatment device |
JP2019531133A (ja) * | 2016-10-03 | 2019-10-31 | ライフセル コーポレーションLifeCell Corporation | 乳房処置器具 |
US10869745B2 (en) | 2016-10-06 | 2020-12-22 | Lifecell Corporation | Tissue matrix with preformed openings or pilot openings |
IT201600120887A1 (it) | 2016-11-30 | 2018-05-30 | Assut Europe Spa | Protesi biologica drenante |
JP6772390B2 (ja) | 2017-03-06 | 2020-10-21 | ティーイーアイ バイオサイエンシズ,インコーポレイテッド | 穿孔された組織移植片 |
USD816220S1 (en) | 2017-04-11 | 2018-04-24 | Tepha, Inc. | Three dimensional mastopexy implant |
USD816221S1 (en) | 2017-04-11 | 2018-04-24 | Tepha, Inc. | Three dimensional mastopexy implant |
CN110612083B (zh) * | 2017-04-11 | 2022-07-12 | 强生消费者公司 | 可延展的敷料 |
WO2018195476A1 (en) * | 2017-04-20 | 2018-10-25 | The Regents Of The University Of California | Systems and methods for acellular dermal matrix fenestrations in prepectoral breast reconstruction |
CN107280810B (zh) * | 2017-05-18 | 2018-11-09 | 西安交通大学 | 一种可降解乳腺支架 |
US11642215B2 (en) | 2018-02-06 | 2023-05-09 | The Trustees Of The University Of Pennsylvania | Kirigami modification of biomedical tissue reinforcing meshes and matrices for expansile two-to-three dimensional conversion |
USD889655S1 (en) | 2018-02-09 | 2020-07-07 | Tepha, Inc. | Three dimensional mastopexy implant |
ES2953544T3 (es) | 2018-02-09 | 2023-11-14 | Tepha Inc | Implante mamario de contorno completo |
USD889654S1 (en) | 2018-02-09 | 2020-07-07 | Tepha, Inc. | Three dimensional mastopexy implant |
USD892329S1 (en) | 2018-07-03 | 2020-08-04 | Tepha, Inc. | Three dimensional mastopexy implant |
CN109172044B (zh) * | 2018-07-24 | 2020-08-14 | 西安交通大学 | 一种可降解梯度孔隙乳腺支架 |
KR20210042925A (ko) * | 2018-07-25 | 2021-04-20 | 이스타블리쉬먼트 렙스 에스.에이. | 대칭 형상을 갖는 임플란트 |
US10813743B2 (en) | 2018-09-07 | 2020-10-27 | Musculoskeletal Transplant Foundation | Soft tissue repair grafts and processes for preparing and using same |
USD895812S1 (en) | 2018-09-07 | 2020-09-08 | Musculoskeletal Transplant Foundation | Soft tissue repair graft |
WO2020072349A1 (en) | 2018-10-02 | 2020-04-09 | Tepha, Inc. | Medical devices to limit movement of breast implants |
WO2020163471A1 (en) | 2019-02-06 | 2020-08-13 | Lifecell Corporation | Meshed dermal tissue matrix products |
CN109745147B (zh) * | 2019-02-28 | 2021-06-29 | 浙江省肿瘤医院 | 一种全自体组织双层包膜适型乳房假体制作方法 |
US11298220B2 (en) | 2019-05-03 | 2022-04-12 | Lifecell Corporation | Breast treatment device |
EP3976127A1 (en) | 2019-05-30 | 2022-04-06 | LifeCell Corporation | Biologic breast implant |
US20210085443A1 (en) * | 2019-09-25 | 2021-03-25 | Allosource | Pre-shaped allograft implant for reconstructive surgical use and methods of manufacture and use |
JP2023501708A (ja) | 2019-11-25 | 2023-01-18 | テファ, インコーポレイテッド | 乳房インプラントの動きを制限するための乳房インプラントラップ、及び関連の方法 |
USD1027375S1 (en) * | 2021-08-27 | 2024-05-21 | Cinmar, Llc | Breast tissue enhancer |
Family Cites Families (150)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US954767A (en) | 1909-01-14 | 1910-04-12 | Norton Co | Composition of matter containing oxids of aluminum and titanium. |
US997575A (en) | 1910-12-14 | 1911-07-11 | Floyd Mitchell | Razor-stropping machine. |
US2108205A (en) * | 1936-12-01 | 1938-02-15 | Elsie L Martin | Breast pad and the like |
US3683424A (en) | 1970-01-30 | 1972-08-15 | William J Pangman | Surgically implantable compound breast prosthesis |
US4298998A (en) * | 1980-12-08 | 1981-11-10 | Naficy Sadeque S | Breast prosthesis with biologically absorbable outer container |
US4984585A (en) | 1983-02-17 | 1991-01-15 | Austad Eric D | Tissue expander |
US4865871A (en) | 1983-08-23 | 1989-09-12 | Board Of Regents The University Of Texas System | Method for cryopreparing biological tissue |
AU593267B2 (en) * | 1986-07-22 | 1990-02-08 | Paul O'keeffe | Implantable fabric pouch for mammary prothesis |
BR8705600A (pt) * | 1987-10-15 | 1988-08-02 | Ricardo Alfredo Bustos | Protese mamaria |
US5366616A (en) | 1987-12-15 | 1994-11-22 | Uop | Hydrocarbon conversion process using a chromium substituted molecular sieve |
FR2630637B1 (fr) | 1988-04-27 | 1997-09-12 | Muller Guy Henri | Nouvelle prothese alveolaire |
US5336616A (en) | 1990-09-12 | 1994-08-09 | Lifecell Corporation | Method for processing and preserving collagen-based tissues for transplantation |
US8067149B2 (en) | 1990-09-12 | 2011-11-29 | Lifecell Corporation | Acellular dermal matrix and method of use thereof for grafting |
US5356429A (en) * | 1991-05-16 | 1994-10-18 | Seare William J Jr | Body pocket maintenance prosthesis |
FR2682284A1 (fr) * | 1991-10-14 | 1993-04-16 | Dessapt Bernard | Prothese mammaire. |
EP0542242B1 (de) | 1991-11-14 | 1997-06-04 | AMOENA Medizin-Orthopädie-Technik GmbH | Verfahren zum Herstellen einer Brustprothese |
US5391203A (en) * | 1992-04-13 | 1995-02-21 | Scott P. Bartlett | Method of draining and filling soft tissue implant |
FR2709947B1 (fr) * | 1993-09-13 | 1995-11-10 | Bard Sa Laboratoires | Filet prothétique galbé et son procédé de fabrication. |
US5437824A (en) * | 1993-12-23 | 1995-08-01 | Moghan Medical Corp. | Method of forming a molded silicone foam implant having open-celled interstices |
CN2203592Y (zh) * | 1994-07-16 | 1995-07-19 | 南京大学 | 附有生理盐水注入孔自动闭塞装置的乳房假体硅橡胶皮囊 |
US5658328A (en) | 1995-03-30 | 1997-08-19 | Johnson; Gerald W. | Endoscopic assisted mastopexy |
US5733337A (en) | 1995-04-07 | 1998-03-31 | Organogenesis, Inc. | Tissue repair fabric |
US5676161A (en) | 1995-04-24 | 1997-10-14 | Baylor College Of Medicine | Surgical procedures for mastopexy and reduction mammaplasty |
US5584884A (en) * | 1995-07-27 | 1996-12-17 | Anthony S. Pignataro | Mammary prosthesis and method of surgically implanting same |
JP3554412B2 (ja) * | 1995-08-07 | 2004-08-18 | 株式会社メニコン | 培養皮膚用基材、培養皮膚およびその製造法 |
US6166288A (en) | 1995-09-27 | 2000-12-26 | Nextran Inc. | Method of producing transgenic animals for xenotransplantation expressing both an enzyme masking or reducing the level of the gal epitope and a complement inhibitor |
FR2746298A1 (fr) * | 1996-03-25 | 1997-09-26 | Bellity Philippe | Prothese de maintien de position et de forme d'un organe |
US5755791A (en) * | 1996-04-05 | 1998-05-26 | Purdue Research Foundation | Perforated submucosal tissue graft constructs |
US6666892B2 (en) | 1996-08-23 | 2003-12-23 | Cook Biotech Incorporated | Multi-formed collagenous biomaterial medical device |
BR9711166A (pt) | 1996-08-23 | 1999-08-17 | Cook Biotech Inc | PrÄtese de enxerto materiais para sua prepara-Æo e m-todos para seu uso |
JPH10158906A (ja) | 1996-11-22 | 1998-06-16 | Torinpu Internatl Japan Kk | 女性用衣類 |
FR2762207B1 (fr) * | 1997-04-17 | 1999-07-30 | Ethnor | Perfectionnements aux protheses sous-cutanees pour plastie mammaire |
AU740913B2 (en) | 1997-09-11 | 2001-11-15 | Purdue Research Foundation | Galactosidase modified submucosal tissue |
US6638308B2 (en) * | 1997-10-10 | 2003-10-28 | John D. Corbitt, Jr. | Bioabsorbable breast implant |
US7637948B2 (en) * | 1997-10-10 | 2009-12-29 | Senorx, Inc. | Tissue marking implant |
US7658727B1 (en) | 1998-04-20 | 2010-02-09 | Medtronic, Inc | Implantable medical device with enhanced biocompatibility and biostability |
CA2334364C (en) | 1998-06-05 | 2011-01-04 | Organogenesis Inc. | Bioengineered flat sheet graft prostheses |
US6933326B1 (en) | 1998-06-19 | 2005-08-23 | Lifecell Coporation | Particulate acellular tissue matrix |
US6099566A (en) * | 1998-09-04 | 2000-08-08 | Pmt Corporation | Prosthetic implant valve cover |
US6740122B1 (en) * | 1998-09-11 | 2004-05-25 | C. R. Bard, Inc. | Preformed curved prosthesis that is adapted to the external iliac vessels |
US6723133B1 (en) * | 1998-09-11 | 2004-04-20 | C. R. Bard, Inc. | Performed curved prosthesis having a reduced incidence of developing wrinkles or folds |
US20030225355A1 (en) | 1998-10-01 | 2003-12-04 | Butler Charles E. | Composite material for wound repair |
ES2402739T3 (es) * | 1998-11-19 | 2013-05-08 | Organogenesis Inc. | Constructos tisulares modificados por bioingeniería y métodos para producirlos y utilizarlos |
US20030082152A1 (en) | 1999-03-10 | 2003-05-01 | Hedrick Marc H. | Adipose-derived stem cells and lattices |
US6777231B1 (en) | 1999-03-10 | 2004-08-17 | The Regents Of The University Of California | Adipose-derived stem cells and lattices |
US6334868B1 (en) | 1999-10-08 | 2002-01-01 | Advanced Cardiovascular Systems, Inc. | Stent cover |
US6203570B1 (en) * | 1999-11-24 | 2001-03-20 | John L. Baeke | Breast implant with position lock |
US20050119737A1 (en) | 2000-01-12 | 2005-06-02 | Bene Eric A. | Ocular implant and methods for making and using same |
US6464726B1 (en) * | 2000-07-13 | 2002-10-15 | Jenna Heljenek | Breast implant system and method of augmentation |
CA2777791A1 (en) * | 2000-09-18 | 2002-03-21 | Organogenesis Inc. | Methods for treating a patient using a bioengineered flat sheet graft prostheses |
US6913626B2 (en) | 2001-08-14 | 2005-07-05 | Mcghan Jim J. | Medical implant having bioabsorbable textured surface |
IL145576A0 (en) * | 2001-09-24 | 2002-06-30 | A prosthesis for physical implant | |
AU2002336670B2 (en) * | 2001-10-26 | 2008-02-07 | Cook Biotech Incorporated | Medical graft device with meshed structure |
US20110009960A1 (en) | 2001-11-16 | 2011-01-13 | Allergan, Inc. | Prosthetic fabric structure |
US6736823B2 (en) | 2002-05-10 | 2004-05-18 | C.R. Bard, Inc. | Prosthetic repair fabric |
US6736854B2 (en) * | 2002-05-10 | 2004-05-18 | C. R. Bard, Inc. | Prosthetic repair fabric with erosion resistant edge |
US7011688B2 (en) * | 2002-05-10 | 2006-03-14 | C.R. Bard, Inc. | Prosthetic repair fabric |
US20100204791A1 (en) | 2002-06-11 | 2010-08-12 | Orbix Medical Ltd. | System for lifting and reshaping soft tissue |
IL150151A (en) * | 2002-06-11 | 2010-11-30 | Mim Minimally Invasive Mastopexy Ltd | Breast lift system |
CA2496761C (en) * | 2002-08-21 | 2015-06-02 | Revivicor, Inc. | Porcine animals lacking any expression of functional alpha 1,3 galactosyltransferase |
CN1511502A (zh) * | 2002-12-30 | 2004-07-14 | 张建军 | 内植抗挛缩圈 |
WO2004096098A1 (en) | 2003-04-29 | 2004-11-11 | Formhold Medical Investment Holdings | Prothesis for soft tissue support |
US7081135B2 (en) | 2003-06-09 | 2006-07-25 | Lane Fielding Smith | Mastopexy stabilization apparatus and method |
US20040260315A1 (en) | 2003-06-17 | 2004-12-23 | Dell Jeffrey R. | Expandable tissue support member and method of forming the support member |
WO2005009134A1 (en) | 2003-07-21 | 2005-02-03 | Lifecell Corporation | ACELLULAR TISSUE MATRICES MADE FROM GALACTOSE α-1,3-GALACTOSE-DEFICIENT TISSUE |
US6802861B1 (en) * | 2003-08-26 | 2004-10-12 | Rsh-Gs Trust | Structured breast implant |
US20050208095A1 (en) | 2003-11-20 | 2005-09-22 | Angiotech International Ag | Polymer compositions and methods for their use |
ITMI20032448A1 (it) * | 2003-12-12 | 2005-06-13 | Angiologica B M S R L | Protesi parietale di rinforzo e metodo di realizzazione della stessa. |
CN1953657A (zh) * | 2004-03-17 | 2007-04-25 | 雷维维科公司 | 来源于缺乏任何功能性α1,3半乳糖基转移酶表达的动物的组织产品 |
CA2559720A1 (en) | 2004-03-17 | 2005-09-29 | Revivicor, Inc. | Tissue products derived from animals lacking any expression of functional alpha 1,3 galactosyltransferase |
DE102004014573A1 (de) * | 2004-03-25 | 2005-10-27 | BEGO Bremer Goldschlägerei Wilh. Herbst GmbH & Co. KG | Verfahren zur Herstellung einer Muffel für den Fein- oder Modellguss, Verfahren zum Herstellen eines metallischen, keramischen oder glaskeramischen Guss- oder Pressobjekts und Kit zur Herstellung eines solchen Objekts |
WO2005094721A1 (en) | 2004-03-30 | 2005-10-13 | Proxy Biomedical Limited | A medical device |
US7351197B2 (en) * | 2004-05-07 | 2008-04-01 | Ams Research Corporation | Method and apparatus for cystocele repair |
US7476249B2 (en) * | 2004-08-06 | 2009-01-13 | Frank Robert E | Implantable prosthesis for positioning and supporting a breast implant |
US8007531B2 (en) * | 2004-08-06 | 2011-08-30 | Frank Robert E | Implantable prosthesis for positioning and supporting a breast implant |
EP1796693A2 (en) | 2004-08-26 | 2007-06-20 | Chandrashekhar P. Pathak | Implantable tissue compositions and method |
US7641688B2 (en) * | 2004-09-16 | 2010-01-05 | Evera Medical, Inc. | Tissue augmentation device |
US9339403B2 (en) | 2004-11-12 | 2016-05-17 | Icon Medical Corp. | Medical adhesive for medical devices |
US20100303880A1 (en) | 2005-04-28 | 2010-12-02 | Reddy Harry K | Tissue scaffolding comprising surface folds for tissue engineering |
WO2006135998A2 (en) | 2005-06-24 | 2006-12-28 | Wagenfuhr Jr J | Implantable prosthesis with double convexity |
JP2008546498A (ja) | 2005-06-28 | 2008-12-25 | グリックスマン,アミ | ヒト用埋め込み型組織拡張器 |
WO2007004214A2 (en) * | 2005-07-04 | 2007-01-11 | Sergey Popov | Implant assembly |
US20070038299A1 (en) * | 2005-08-12 | 2007-02-15 | Arthrotek, Inc | Multilayer microperforated implant |
US20090216338A1 (en) * | 2005-09-12 | 2009-08-27 | Peter Gingras | Soft tissue implants and methods for making same |
WO2007040557A1 (en) | 2005-09-21 | 2007-04-12 | Surmodics, Inc. | Coatings and articles including natural biodegradable polysaccharides |
US20070088299A1 (en) | 2005-10-17 | 2007-04-19 | Emily Ayre | Emesis kit |
US20070116678A1 (en) * | 2005-11-23 | 2007-05-24 | Hsing-Wen Sung | Medical device with living cell sheet |
US20080260853A1 (en) * | 2006-02-22 | 2008-10-23 | Firestone Leigh H | Extracellular matrix as surgical adjunct in a lumpectomy procedure |
WO2007134134A2 (en) * | 2006-05-09 | 2007-11-22 | Lifecell Corporation | Reinforced biological tissue |
DE102006029605A1 (de) * | 2006-06-26 | 2007-12-27 | Lazar, Harald, Dr. | Brustimplantat |
US8480557B2 (en) * | 2006-07-27 | 2013-07-09 | Refine, Llc | Nonaugmentive mastopexy |
EP2068766B1 (en) * | 2006-07-31 | 2011-10-19 | Organogenesis, Inc. | Mastopexy and breast reconstruction prostheses |
CA2665209C (en) * | 2006-10-03 | 2016-01-05 | Alure Medical, Inc. | Minimally invasive tissue support |
US7998152B2 (en) * | 2006-12-21 | 2011-08-16 | Frank Robert E | Implantable prosthesis for periareolar mastopexy |
WO2008086469A1 (en) * | 2007-01-10 | 2008-07-17 | Cook Biotech Incorporated | Implantable devices useful for reinforcing a surgically created stoma |
US8383092B2 (en) | 2007-02-16 | 2013-02-26 | Knc Ner Acquisition Sub, Inc. | Bioadhesive constructs |
EP2129339B1 (en) | 2007-03-29 | 2015-03-04 | Tyrx, Inc. | Biodegradable, polymer coverings for breast implants |
US20080281418A1 (en) * | 2007-05-09 | 2008-11-13 | Leigh Hunt Firestone | Breast implant articles of multi-layered sheets of extracellular matrix or balled strips and pieces of extracellular matrix |
US20080281419A1 (en) * | 2007-05-10 | 2008-11-13 | Matheny Robert G | Breast implants and compositions of extracellular matrix |
US9149496B2 (en) | 2007-05-10 | 2015-10-06 | Cormatrix Cardiovascular, Inc. | ECM Constructs for treating damaged biological tissue |
CL2008001272A1 (es) | 2007-06-24 | 2008-10-03 | Gary Pierre Lauryssen | Sosten prostetico de mamas humanas que comprende una lamina continua de malla biocompatible con forma de copa que se puede asegurar entre la piel y la estructura glandular de una mama humana con una apertura a traves de la cual se ubica la estructura |
US8101116B2 (en) * | 2007-09-19 | 2012-01-24 | Ethicon, Inc. | Preformed support device and method and apparatus for manufacturing the same |
ES2701012T3 (es) * | 2007-09-19 | 2019-02-20 | Ethicon Inc | Dispositivo de malla con contorno natural, preformado, tridimensional para soporte de implante mamario |
MX2010004047A (es) * | 2007-10-16 | 2010-06-25 | Orbix Medical Ltd | Un sistema y metodo para reconformar tejido blando. |
US8313527B2 (en) | 2007-11-05 | 2012-11-20 | Allergan, Inc. | Soft prosthesis shell texturing method |
US20110035004A1 (en) * | 2007-11-14 | 2011-02-10 | Maxwell G | Interfaced medical implant |
US8876899B2 (en) | 2007-11-14 | 2014-11-04 | G. Patrick Maxwell | Breast implant assembly |
US8425600B2 (en) * | 2007-11-14 | 2013-04-23 | G. Patrick Maxwell | Interfaced medical implant assembly |
BRPI0820449B8 (pt) * | 2007-11-14 | 2021-06-22 | Patrick Maxwell G | conjunto de implante médico para um hospedeiro |
US20110293666A1 (en) | 2007-11-28 | 2011-12-01 | Xianyan Wang | Bioengineered Tissue Constructs and Methods for Production and Use |
US20090198332A1 (en) * | 2008-02-05 | 2009-08-06 | Hilton Becker | Method for texturing the surface of a synthetic implant |
AU2008352542B2 (en) | 2008-03-14 | 2013-07-18 | Cook Biotech Incorporated | Graft materials and methods for staged delivery of bioactive components |
US7753954B2 (en) | 2008-04-11 | 2010-07-13 | American Breast Care LP | Breast prosthesis for patients with edema |
US20100023029A1 (en) * | 2008-07-23 | 2010-01-28 | Bodyaesthetic Research Center, Inc. | Mesh Device for Immediate Breast Construction and Uses Thereof |
AU2009277252B2 (en) | 2008-07-30 | 2014-01-16 | Mesynthes Limited | Tissue scaffolds derived from forestomach extracellular matrix |
US9204953B2 (en) | 2008-12-15 | 2015-12-08 | Allergan, Inc. | Biocompatible surgical scaffold with varying stretch |
US8986377B2 (en) | 2009-07-21 | 2015-03-24 | Lifecell Corporation | Graft materials for surgical breast procedures |
MX2012006759A (es) | 2009-12-17 | 2012-07-30 | Univ Kingston | Tejido adiposo descelularizado. |
CN102892880A (zh) | 2010-01-14 | 2013-01-23 | 奥加诺吉尼西斯公司 | 生物工程化组织构建物及其制备和使用方法 |
AU2011209793A1 (en) | 2010-01-28 | 2012-08-16 | Allergan, Inc. | Open celled silicone foams, implants including them and processes for making same |
US20140257481A1 (en) | 2010-04-29 | 2014-09-11 | BioStruxs, LLC | Breast Reconstruction Device and Methods |
US8858647B2 (en) | 2010-05-05 | 2014-10-14 | Barry Markman | Method and apparatus for a process creating an internal tissue graft for animal and human reconstructive purposes |
CA2799201C (en) | 2010-05-11 | 2016-09-20 | Allergan, Inc. | Porogen compositions, methods of making and uses |
CN103068413B (zh) | 2010-07-08 | 2015-12-16 | 生命细胞公司 | 用于使组织基质成形的方法 |
US10195114B2 (en) | 2012-11-19 | 2019-02-05 | Guill Tool & Engineering Co., Inc | Microlayer coextrusion to create a time-release drug substance delivery product |
WO2012122215A2 (en) | 2011-03-09 | 2012-09-13 | Galatea Corporation | Systems and methods for mastopexy |
US20140088700A1 (en) | 2011-06-08 | 2014-03-27 | Allergan, Inc. | Method for using a silk derived bioresorbable scaffold in breast reconstruction |
US9132194B2 (en) | 2011-07-12 | 2015-09-15 | Warsaw Orthopedic, Inc. | Medical devices and methods comprising an adhesive sheet containing a drug depot |
WO2013009993A1 (en) | 2011-07-12 | 2013-01-17 | Bengtson Bradley P | Surgical fixation devices, systems, and methods |
ES2729712T3 (es) | 2011-12-20 | 2019-11-05 | Lifecell Corp | Productos de tejido de lámina |
ES2596522T3 (es) | 2012-01-13 | 2017-01-10 | Lifecell Corporation | Prótesis mamarias y métodos de fabricación de prótesis mamarias |
WO2013126550A2 (en) | 2012-02-22 | 2013-08-29 | Kci Licensing, Inc. | New compositions, the preparation and use thereof |
WO2013134269A2 (en) | 2012-03-06 | 2013-09-12 | Kci Licensing, Inc. | New compositions, the preparation and use thereof |
CA2868793C (en) | 2012-03-26 | 2021-01-05 | Pfm Medical, Inc. | Biocompatible mesh implant |
WO2013192197A1 (en) | 2012-06-21 | 2013-12-27 | Lifecell Corporation | Implantable prosthesis having acellular tissue attachments |
US9504828B2 (en) | 2012-07-26 | 2016-11-29 | Nyxoah SA | Electrical contacts on a medical device patch |
ES2409691B1 (es) | 2012-11-16 | 2013-11-21 | Federico MAYO MARTIN | Implante mamario |
WO2014123665A1 (en) | 2013-02-06 | 2014-08-14 | Kci Licensing, Inc. | Polymers, preparation and use thereof |
US9433489B2 (en) | 2013-03-12 | 2016-09-06 | Soft Tissue Regeneration, Inc. | Absorbable synthetic braided matrix for breast reconstruction and hernia repair |
US9655715B2 (en) | 2013-07-11 | 2017-05-23 | Tepha, Inc. | Absorbable implants for plastic surgery |
EP3019206B1 (en) | 2013-07-11 | 2019-12-04 | Tepha, Inc. | Absorbable implants for plastic surgery |
CN103393482B (zh) | 2013-08-14 | 2016-04-06 | 北京瑞健高科生物科技有限公司 | 一种基于组织基质材料的乳房假体支撑装置及其制备方法 |
US10898312B2 (en) | 2013-10-28 | 2021-01-26 | The Regents Of The University Of California | Tissue grafts with fenestrations |
US10130457B2 (en) | 2014-03-05 | 2018-11-20 | Tela Bio, Inc. | Surgical attachment device |
EP2995278A1 (en) | 2014-09-09 | 2016-03-16 | Klinikum rechts der Isar der Technischen Universität München | Medical/surgical implant |
US20160228236A1 (en) | 2015-02-11 | 2016-08-11 | Novus Scientific Ab | Breast implant support device with large back surface area |
US10307237B2 (en) | 2015-05-15 | 2019-06-04 | Lifecell Corporation | Tissue matrices and methods of treatment |
US10945831B2 (en) | 2016-06-03 | 2021-03-16 | Musculoskeletal Transplant Foundation | Asymmetric tissue graft |
EP3506854B1 (en) | 2016-08-31 | 2020-08-19 | LifeCell Corporation | Breast treatment device |
JP2019531133A (ja) | 2016-10-03 | 2019-10-31 | ライフセル コーポレーションLifeCell Corporation | 乳房処置器具 |
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CA2767399C (en) | 2019-03-12 |
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AU2010276354B2 (en) | 2014-10-02 |
CN102470032B (zh) | 2015-07-15 |
JP2013500062A (ja) | 2013-01-07 |
CA3031402A1 (en) | 2011-01-27 |
EP2456391B1 (en) | 2020-05-13 |
US10449034B2 (en) | 2019-10-22 |
EP3711710A1 (en) | 2020-09-23 |
US10835370B2 (en) | 2020-11-17 |
EP2456391A2 (en) | 2012-05-30 |
CA3031402C (en) | 2021-10-19 |
US8986377B2 (en) | 2015-03-24 |
WO2011011394A3 (en) | 2011-03-17 |
JP5603423B2 (ja) | 2014-10-08 |
AU2010276354A1 (en) | 2012-02-02 |
US20110022171A1 (en) | 2011-01-27 |
CN105078613A (zh) | 2015-11-25 |
WO2011011394A2 (en) | 2011-01-27 |
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