JP5832451B2 - 抗真菌医薬組成物 - Google Patents

抗真菌医薬組成物 Download PDF

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Publication number
JP5832451B2
JP5832451B2 JP2012552591A JP2012552591A JP5832451B2 JP 5832451 B2 JP5832451 B2 JP 5832451B2 JP 2012552591 A JP2012552591 A JP 2012552591A JP 2012552591 A JP2012552591 A JP 2012552591A JP 5832451 B2 JP5832451 B2 JP 5832451B2
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JP
Japan
Prior art keywords
pharmaceutical composition
general formula
compound represented
polyhydric alcohol
dioxolane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2012552591A
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English (en)
Japanese (ja)
Other versions
JP2013528157A (ja
JP2013528157A5 (enExample
Inventor
久保田　信雄
信雄 久保田
小林　浩一
浩一 小林
孝明 増田
孝明 増田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pola Pharma Inc
Nihon Nohyaku Co Ltd
Original Assignee
Pola Pharma Inc
Nihon Nohyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Priority to JP2012552591A priority Critical patent/JP5832451B2/ja
Publication of JP2013528157A publication Critical patent/JP2013528157A/ja
Publication of JP2013528157A5 publication Critical patent/JP2013528157A5/ja
Application granted granted Critical
Publication of JP5832451B2 publication Critical patent/JP5832451B2/ja
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2012552591A 2010-06-11 2011-06-10 抗真菌医薬組成物 Active JP5832451B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2012552591A JP5832451B2 (ja) 2010-06-11 2011-06-10 抗真菌医薬組成物

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2010148255 2010-06-11
JP2010148255 2010-06-11
JP2010181923 2010-07-30
JP2010181923 2010-07-30
JP2012552591A JP5832451B2 (ja) 2010-06-11 2011-06-10 抗真菌医薬組成物
PCT/JP2011/063860 WO2011155640A1 (en) 2010-06-11 2011-06-10 Antimycotic pharmaceutical composition

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015123928A Division JP5938497B2 (ja) 2010-06-11 2015-06-19 抗真菌医薬組成物

Publications (3)

Publication Number Publication Date
JP2013528157A JP2013528157A (ja) 2013-07-08
JP2013528157A5 JP2013528157A5 (enExample) 2014-07-03
JP5832451B2 true JP5832451B2 (ja) 2015-12-16

Family

ID=44544289

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012552591A Active JP5832451B2 (ja) 2010-06-11 2011-06-10 抗真菌医薬組成物
JP2015123928A Active JP5938497B2 (ja) 2010-06-11 2015-06-19 抗真菌医薬組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015123928A Active JP5938497B2 (ja) 2010-06-11 2015-06-19 抗真菌医薬組成物

Country Status (6)

Country Link
US (1) US8962669B2 (enExample)
EP (1) EP2579847A1 (enExample)
JP (2) JP5832451B2 (enExample)
KR (1) KR101806304B1 (enExample)
CN (1) CN102933201B (enExample)
WO (1) WO2011155640A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10898470B1 (en) 2019-08-13 2021-01-26 Sato Pharmaceutical Co., Ltd. Pharmaceutical composition containing antifungal agent as active ingredient

Families Citing this family (18)

* Cited by examiner, † Cited by third party
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US10130610B2 (en) 2009-04-09 2018-11-20 Pola Pharma Inc. Antimycotic pharmaceutical composition
KR101409792B1 (ko) 2009-04-09 2014-06-19 니혼노야쿠가부시키가이샤 항진균성 약제학적 조성물
WO2011024620A1 (en) 2009-08-25 2011-03-03 Pola Pharma Inc. Antimycotic pharmaceutical composition
CN104105472A (zh) 2011-12-20 2014-10-15 维奥姆生物科学有限公司 用于治疗真菌感染的局部油组合物
CN103179634A (zh) * 2011-12-21 2013-06-26 株式会社Ntt都科摩 一种伙伴发现和选择方法、装置及系统
WO2014017411A1 (ja) * 2012-07-23 2014-01-30 マルホ株式会社 爪白癬治療用外用剤
US9199977B2 (en) 2012-09-14 2015-12-01 Pola Pharma Inc. Crystal having crystal habits and pharmaceutical composition obtained by processing the crystal
RU2621615C2 (ru) * 2012-09-14 2017-06-06 Пола Фарма Инк. Фармацевтическая композиция, содержащая луликоназол
CN104619704B (zh) 2012-09-14 2017-12-05 宝丽制药股份有限公司 表面自由能用于分化评价晶体的用途，基于表面自由能作为指标评价的晶体，以及通过包含所述晶体制备的药物组合物
JP5460797B1 (ja) * 2012-09-14 2014-04-02 株式会社ポーラファルマ アミド誘導体及び安定性指標としてのその使用
CN104284662A (zh) 2012-09-14 2015-01-14 宝丽制药股份有限公司 晶体及包含该晶体的药物制剂
JP5589110B1 (ja) 2013-03-08 2014-09-10 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物
JP2016518306A (ja) * 2013-05-17 2016-06-23 株式会社ポーラファルマ アスペルギルス、カンジダ等を病原体とする疾患用の医薬組成物
JP5680161B1 (ja) 2013-09-06 2015-03-04 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物
JP5587488B1 (ja) 2013-12-12 2014-09-10 株式会社ポーラファルマ ルリコナゾールを含有する製剤の評価方法及び指標物質
CN107865825B (zh) * 2016-09-28 2022-05-20 四川海思科制药有限公司 一种卢立康唑外用喷雾剂药物组合物及其制备方法
CN108934161A (zh) * 2017-03-29 2018-12-04 日本农药株式会社 用于治疗感染症的医药组合物
CN114981379B (zh) * 2019-10-08 2024-05-14 哈尔卢克斯股份有限公司 治疗甲癣的组合物和方法

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US4861764A (en) 1986-11-17 1989-08-29 Macro Chem. Corp. Percutaneous absorption enhancers, compositions containing same and method of use
JP3081766B2 (ja) 1994-05-06 2000-08-28 東興薬品工業株式会社 角質貯留型抗真菌外用組成物
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EP0839035B1 (en) * 1995-07-08 2002-10-02 Nihon Nohyaku Co., Ltd. Antifungal agent, compound therefor, process for producing the same
JP3278738B2 (ja) 1995-07-08 2002-04-30 日本農薬株式会社 抗真菌剤
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JP2002114680A (ja) * 2000-07-31 2002-04-16 Nippon Nohyaku Co Ltd 抗真菌剤
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KR101409792B1 (ko) * 2009-04-09 2014-06-19 니혼노야쿠가부시키가이샤 항진균성 약제학적 조성물
US10130610B2 (en) 2009-04-09 2018-11-20 Pola Pharma Inc. Antimycotic pharmaceutical composition
WO2011024620A1 (en) 2009-08-25 2011-03-03 Pola Pharma Inc. Antimycotic pharmaceutical composition
CN104284662A (zh) 2012-09-14 2015-01-14 宝丽制药股份有限公司 晶体及包含该晶体的药物制剂
CN104619704B (zh) 2012-09-14 2017-12-05 宝丽制药股份有限公司 表面自由能用于分化评价晶体的用途，基于表面自由能作为指标评价的晶体，以及通过包含所述晶体制备的药物组合物
US9199977B2 (en) 2012-09-14 2015-12-01 Pola Pharma Inc. Crystal having crystal habits and pharmaceutical composition obtained by processing the crystal
RU2621615C2 (ru) 2012-09-14 2017-06-06 Пола Фарма Инк. Фармацевтическая композиция, содержащая луликоназол
JP5460797B1 (ja) 2012-09-14 2014-04-02 株式会社ポーラファルマ アミド誘導体及び安定性指標としてのその使用
JP5589110B1 (ja) 2013-03-08 2014-09-10 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10898470B1 (en) 2019-08-13 2021-01-26 Sato Pharmaceutical Co., Ltd. Pharmaceutical composition containing antifungal agent as active ingredient
KR20220035954A (ko) 2019-08-13 2022-03-22 사토 세이야쿠 가부시키가이샤 항진균약을 유효성분으로 하는 의약 조성물
US11738006B2 (en) 2019-08-13 2023-08-29 Sato Pharmaceutical Co., Ltd. Pharmaceutical composition containing antifungal agent as active ingredient

Also Published As

Publication number Publication date
US20130090365A1 (en) 2013-04-11
KR101806304B1 (ko) 2017-12-07
KR20130112727A (ko) 2013-10-14
US8962669B2 (en) 2015-02-24
JP5938497B2 (ja) 2016-06-22
WO2011155640A1 (en) 2011-12-15
CN102933201A (zh) 2013-02-13
JP2013528157A (ja) 2013-07-08
EP2579847A1 (en) 2013-04-17
JP2015163655A (ja) 2015-09-10
CN102933201B (zh) 2015-12-16

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