JP5786195B2 - 舌下フィルム - Google Patents
舌下フィルム Download PDFInfo
- Publication number
- JP5786195B2 JP5786195B2 JP2013544855A JP2013544855A JP5786195B2 JP 5786195 B2 JP5786195 B2 JP 5786195B2 JP 2013544855 A JP2013544855 A JP 2013544855A JP 2013544855 A JP2013544855 A JP 2013544855A JP 5786195 B2 JP5786195 B2 JP 5786195B2
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- film
- apomorphine
- unit dosage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 239000008194 pharmaceutical composition Substances 0.000 claims description 171
- 239000002552 dosage form Substances 0.000 claims description 163
- 229960004046 apomorphine Drugs 0.000 claims description 162
- VMWNQDUVQKEIOC-CYBMUJFWSA-N apomorphine Chemical compound C([C@H]1N(C)CC2)C3=CC=C(O)C(O)=C3C3=C1C2=CC=C3 VMWNQDUVQKEIOC-CYBMUJFWSA-N 0.000 claims description 160
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 75
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 74
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- SKYZYDSNJIOXRL-BTQNPOSSSA-N (6ar)-6-methyl-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinoline-10,11-diol;hydrochloride Chemical compound Cl.C([C@H]1N(C)CC2)C3=CC=C(O)C(O)=C3C3=C1C2=CC=C3 SKYZYDSNJIOXRL-BTQNPOSSSA-N 0.000 claims description 53
- 229960003990 apomorphine hydrochloride Drugs 0.000 claims description 53
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| EP2765999A4 (en) * | 2011-10-14 | 2015-04-01 | Purdue Research Foundation | EASY MULTILAYER UNIT WITH PRESENT FUNCTIONS AND COMBINATIONS |
| EP2895153A1 (en) * | 2012-09-11 | 2015-07-22 | University Of The Witwatersrand, Johannesburg | Fast dissolving ocular insert |
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