PT2446881E - Películas de dissolução oral - Google Patents

Películas de dissolução oral Download PDF

Info

Publication number
PT2446881E
PT2446881E PT121523013T PT12152301T PT2446881E PT 2446881 E PT2446881 E PT 2446881E PT 121523013 T PT121523013 T PT 121523013T PT 12152301 T PT12152301 T PT 12152301T PT 2446881 E PT2446881 E PT 2446881E
Authority
PT
Portugal
Prior art keywords
orally dissolving
dissolving films
films
orally
dissolving
Prior art date
Application number
PT121523013T
Other languages
English (en)
Inventor
Shing Yue Chan
Li-Lan Chen
Dushendra J Chetty
John Jiangnan Liu
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34102944&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2446881(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of PT2446881E publication Critical patent/PT2446881E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/724Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Psychiatry (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT121523013T 2003-07-24 2004-07-22 Películas de dissolução oral PT2446881E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48985503P 2003-07-24 2003-07-24

Publications (1)

Publication Number Publication Date
PT2446881E true PT2446881E (pt) 2014-06-11

Family

ID=34102944

Family Applications (2)

Application Number Title Priority Date Filing Date
PT47789813T PT1648421T (pt) 2003-07-24 2004-07-22 Películas de dissolução oral
PT121523013T PT2446881E (pt) 2003-07-24 2004-07-22 Películas de dissolução oral

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT47789813T PT1648421T (pt) 2003-07-24 2004-07-22 Películas de dissolução oral

Country Status (24)

Country Link
US (1) US9675548B2 (pt)
EP (2) EP2446881B1 (pt)
JP (4) JP2006528636A (pt)
CN (1) CN100508976C (pt)
AR (1) AR045076A1 (pt)
AU (2) AU2004259006B2 (pt)
BR (1) BRPI0412752B8 (pt)
CA (1) CA2533577C (pt)
CL (2) CL2008002406A1 (pt)
DK (2) DK2446881T3 (pt)
ES (2) ES2466943T3 (pt)
HK (1) HK1169802A1 (pt)
HR (1) HRP20171944T1 (pt)
HU (1) HUE037508T2 (pt)
LT (1) LT1648421T (pt)
MX (1) MXPA06000852A (pt)
PE (1) PE20050496A1 (pt)
PL (2) PL2446881T3 (pt)
PT (2) PT1648421T (pt)
RU (2) RU2351315C2 (pt)
SI (1) SI1648421T1 (pt)
TW (1) TW200514579A (pt)
UY (1) UY28431A1 (pt)
WO (1) WO2005009386A2 (pt)

Families Citing this family (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8627828B2 (en) * 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
JP4931596B2 (ja) 2003-11-07 2012-05-16 ユーエス スモークレス タバコ カンパニー リミテッド ライアビリティ カンパニー タバコ組成物
DE102005033943A1 (de) * 2005-07-20 2007-02-22 Hexal Ag Nicht-ausspuckbarer, oraler, schnell-zerfallender Film für ein Neuroleptikum
DE102005058569B4 (de) * 2005-12-08 2010-07-15 Lts Lohmann Therapie-Systeme Ag Schaumwafer mit Polyvinylalkohol-Polyethylenglycol-Pfropfcopolymer
US7810507B2 (en) 2006-02-10 2010-10-12 R. J. Reynolds Tobacco Company Smokeless tobacco composition
EP1993509A2 (en) * 2006-02-17 2008-11-26 Novartis AG Disintegrable oral films
WO2008005509A2 (en) * 2006-07-06 2008-01-10 Massachusetts Institute Of Technology Methods and compositions for altering biological surfaces
WO2008080773A1 (de) * 2006-12-29 2008-07-10 Basf Se Verfahren zur herstellung von festen dosierungsformen enthaltend pfropfcopolymere
FR2912915B1 (fr) * 2007-02-28 2012-11-16 Pf Medicament Film a desintegration rapide pour l'administration buccale de substances actives.
CA2678876C (en) * 2007-03-07 2015-11-24 Novartis Ag Orally administrable films
SI2152250T1 (sl) * 2007-05-07 2020-06-30 Evonik Operations Gmbh Trdne dozirne oblike, ki vsebujejo enterično oplaščenje s pospešenim sproščanjem zdravila
WO2009015142A2 (en) 2007-07-23 2009-01-29 R.J.Reynolds Tobacco Company Smokeless tobacco compositions and methods for treating tobacco for use therein
WO2009043588A2 (en) * 2007-10-02 2009-04-09 LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH Ph regulating antibacterial films for the oral or vaginal cavity
MY185299A (en) * 2007-10-11 2021-04-30 Philip Morris Products Sa Smokeless tobacco product
US9125434B2 (en) 2007-10-11 2015-09-08 Philip Morris Products S.A. Smokeless tobacco product, smokeless tobacco product in the form of a sheet, extrudable tobacco composition, method for manufacturing a smokeless tobacco product, method for delivering super bioavailable nicotine contained in tobacco to a user, and packaged smokeless tobacco product sheet
JP2009102287A (ja) * 2007-10-19 2009-05-14 Seiji Sakao 禁煙用の辛い唐辛子
WO2009073190A1 (en) * 2007-12-04 2009-06-11 Swedish Match North America, Inc. Fast dissolving films and coatings for controlled release of flavors, active pharmaceutical ingredients, food substances, and nicotine
AU2008334684A1 (en) * 2007-12-11 2009-06-18 Novartis Ag Multi-zone films
WO2009080021A1 (en) 2007-12-20 2009-07-02 Fertin Pharma A/S Compressed chewing gum tablet
WO2009080022A1 (en) * 2007-12-20 2009-07-02 Fertin Pharma A/S Compressed chewing gum tablet
CN102014883A (zh) * 2008-01-31 2011-04-13 麦克内尔-Ppc股份有限公司 具有调释型活性成分的可食用膜条片
CN102014882A (zh) * 2008-01-31 2011-04-13 麦克内尔-Ppc股份有限公司 即刻释放活性成分的可食用膜条片
US20110052699A1 (en) * 2008-02-13 2011-03-03 Adrian Funke Drug delivery system with stabilising effect
CN102006863A (zh) * 2008-04-15 2011-04-06 盐野义制药株式会社 膜组合物
AU2009315898B2 (en) * 2008-11-13 2015-07-23 Nogra Pharma Limited Antisense compositions and methods of making and using same
EP2210595A1 (en) * 2009-01-14 2010-07-28 LEK Pharmaceuticals d.d. Active coating of pharmaceutical dosage forms
US20100256197A1 (en) * 2009-04-02 2010-10-07 Silver Eagle Labs Nv, Llc Nicotine Dissolving Film With Or Without Menthol
US20100256215A1 (en) * 2009-04-02 2010-10-07 Silver Eagle Labs Nv, Llc Menthol-Melatonin Dissolving Film
BRPI1007725A2 (pt) 2009-05-12 2016-02-16 Bpsi Holdings Llc composição de revestimento de liberação imediata com propriedades melhoradas de barreira à umidade, suspensão aquosa, substrato oral revestido, forma de dosagem oral e método para preparação da mesma
EP2432437A4 (en) * 2009-05-21 2012-12-19 Bionex Pharmaceuticals Llc TWO- AND ONE-LAYER DOSAGE FORMS
US8434496B2 (en) 2009-06-02 2013-05-07 R. J. Reynolds Tobacco Company Thermal treatment process for tobacco materials
US8944072B2 (en) 2009-06-02 2015-02-03 R.J. Reynolds Tobacco Company Thermal treatment process for tobacco materials
KR102017009B1 (ko) * 2009-06-12 2019-09-02 선오비온 파마슈티컬스 인코포레이티드 설하 아포모르핀
WO2010146601A1 (en) * 2009-06-15 2010-12-23 Unijules Life Sciences Ltd Rapid dissolvable oral film for delivering herbal extract/s with or without other pharmaceutically active agents
US20110139164A1 (en) * 2009-12-15 2011-06-16 R. J. Reynolds Tobacco Company Tobacco Product And Method For Manufacture
US20110220130A1 (en) * 2009-12-15 2011-09-15 John-Paul Mua Tobacco Product And Method For Manufacture
US20130014771A1 (en) 2011-01-13 2013-01-17 R. J. Reynolds Tobacco Company Tobacco-derived components and materials
US8955523B2 (en) 2010-01-15 2015-02-17 R.J. Reynolds Tobacco Company Tobacco-derived components and materials
US8397945B2 (en) 2010-02-23 2013-03-19 R.J. Reynolds Tobacco Company Dispensing container
RU2560693C2 (ru) * 2010-03-23 2015-08-20 Апр Эпплайд Фарма Рисерч, С.А. Быстро растворяющиеся системы, освобождающие лекарственные препараты
US9039839B2 (en) 2010-04-08 2015-05-26 R.J. Reynolds Tobacco Company Smokeless tobacco composition comprising tobacco-derived material and non-tobacco plant material
EP2557947A1 (en) 2010-04-14 2013-02-20 Altria Client Services Inc. Preformed smokeless tobacco product
US9402415B2 (en) 2010-04-21 2016-08-02 R. J. Reynolds Tobacco Company Tobacco seed-derived components and materials
WO2011134846A1 (en) * 2010-04-27 2011-11-03 Novartis Ag Oral dosage forms
US20110268809A1 (en) 2010-04-28 2011-11-03 Paul Andrew Brinkley Nicotine-Containing Pharmaceutical Compositions
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
US9675102B2 (en) 2010-09-07 2017-06-13 R. J. Reynolds Tobacco Company Smokeless tobacco product comprising effervescent composition
DE102010048408A1 (de) 2010-10-15 2012-04-19 Lts Lohmann Therapie-Systeme Ag Laminat mit verbessertem Wasserretentionsverhalten
US20120125354A1 (en) 2010-11-18 2012-05-24 R.J. Reynolds Tobacco Company Fire-Cured Tobacco Extract and Tobacco Products Made Therefrom
EA031156B1 (ru) 2010-12-16 2018-11-30 Суновион Фармасьютикалз Инк. Сублингвальные пленки
US20120152265A1 (en) 2010-12-17 2012-06-21 R.J. Reynolds Tobacco Company Tobacco-Derived Syrup Composition
US9107453B2 (en) 2011-01-28 2015-08-18 R.J. Reynolds Tobacco Company Tobacco-derived casing composition
US8893725B2 (en) 2011-01-28 2014-11-25 R. J. Reynolds Tobacco Company Polymeric materials derived from tobacco
US9254001B2 (en) 2011-04-27 2016-02-09 R.J. Reynolds Tobacco Company Tobacco-derived components and materials
US9192193B2 (en) 2011-05-19 2015-11-24 R.J. Reynolds Tobacco Company Molecularly imprinted polymers for treating tobacco material and filtering smoke from smoking articles
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
WO2013056159A1 (en) * 2011-10-13 2013-04-18 Jaleva Pharmaceuticals, Llc Methods and compositions for rapid transbuccal delivery of active agents
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
US20130125907A1 (en) 2011-11-17 2013-05-23 Michael Francis Dube Method for Producing Triethyl Citrate from Tobacco
US10881132B2 (en) 2011-12-14 2021-01-05 R.J. Reynolds Tobacco Company Smokeless tobacco product comprising effervescent composition
US9763928B2 (en) 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
WO2013142483A1 (en) 2012-03-19 2013-09-26 R. J. Reynolds Tobacco Company Method for treating an extracted tobacco pulp and tobacco products made therefrom
US10799451B2 (en) * 2012-03-27 2020-10-13 Nicoccino Ab Nicotine formulation
US9822257B2 (en) 2012-07-23 2017-11-21 Crayola Llc Dissolvable films and methods of using the same
US20150250887A1 (en) * 2012-10-12 2015-09-10 Jaleva Pharmaceuticals, Llc Method of preparing resin tinctures
WO2014085445A1 (en) 2012-11-28 2014-06-05 Jaleva Pharmaceuticals, Llc Dual chamber applicator
US20140166027A1 (en) * 2012-12-14 2014-06-19 Richard C. Fuisz Enhanced Delivery of Nicotine, THC, Tobacco, Cannabidiol or Base Alkaloid from an Electronic Cigarette or Other Vapor Producing Device Through Use of an Absorption Conditioning Unit
US20140166028A1 (en) * 2012-12-14 2014-06-19 Richard C. Fuisz Enhanced Delivery of Nicotine, THC, Tobacco, Cannabidiol or Base Alkaloid from an Electronic Cigarette or Other Vapor or Smoke Producing Device Through Use of an Absorption Conditioning Unit
US9289011B2 (en) 2013-03-07 2016-03-22 R.J. Reynolds Tobacco Company Method for producing lutein from tobacco
US9420827B2 (en) 2013-03-14 2016-08-23 Altria Client Services Llc Soft oral product
US20140275148A1 (en) * 2013-03-15 2014-09-18 Novus Pharma LLC Orally administrable, self-supporting dissolving film dosage forms
US10799548B2 (en) * 2013-03-15 2020-10-13 Altria Client Services Llc Modifying taste and sensory irritation of smokeless tobacco and non-tobacco products
WO2014188079A1 (en) * 2013-05-23 2014-11-27 Åbo Akademi University Printed dosage forms
US20150034109A1 (en) 2013-08-02 2015-02-05 R.J. Reynolds Tobacco Company Process for Producing Lignin from Tobacco
US11503853B2 (en) 2013-09-09 2022-11-22 R.J. Reynolds Tobacco Company Smokeless tobacco composition incorporating a botanical material
WO2015038400A1 (en) * 2013-09-11 2015-03-19 3M Innovative Properties Company Oral compositions
US10357054B2 (en) 2013-10-16 2019-07-23 R.J. Reynolds Tobacco Company Smokeless tobacco pastille
US20150147555A1 (en) * 2013-11-23 2015-05-28 Orahealth Corporation Multilayer mucoadhering patch with a nonadhering layer comprising casein
CN105764491A (zh) 2013-12-09 2016-07-13 度瑞公司 药物活性剂复合物、聚合物复合物,以及包括其的组合物和方法
EP3536313B1 (en) 2013-12-31 2022-02-16 Johnson & Johnson Consumer Inc. Process for forming a shaped film product
JP6517216B2 (ja) 2013-12-31 2019-05-22 ジョンソン・アンド・ジョンソン・コンシューマー・インコーポレイテッド 多層賦形フィルム製品を形成するための単一パス方法
KR102396906B1 (ko) 2013-12-31 2022-05-13 존슨 앤드 존슨 컨수머 인코포레이티드 다층의 형상화된 필름을 형성하기 위한 방법
US9265284B2 (en) 2014-01-17 2016-02-23 R.J. Reynolds Tobacco Company Process for producing flavorants and related materials
CN106999601A (zh) * 2014-12-09 2017-08-01 莫诺索尔克斯有限公司 基于直链多糖的膜产品
DE102015201871B4 (de) * 2015-02-03 2018-04-05 Ferton Holding S.A. Verwendung eines Pulvers als Mittel zur Pulverstrahlbearbeitung in einem Pulverstrahlgerät und Verfahren zur Reinigung von Zähnen
US10881133B2 (en) 2015-04-16 2021-01-05 R.J. Reynolds Tobacco Company Tobacco-derived cellulosic sugar
WO2016172095A1 (en) 2015-04-21 2016-10-27 Cynapsus Therapeutics, Inc. Methods of treating parkinson's disease by administration of apomorphine to an oral mucosa
US20170059554A1 (en) 2015-09-02 2017-03-02 R. J. Reynolds Tobacco Company Method for monitoring use of a tobacco product
ITUB20153446A1 (it) * 2015-09-07 2017-03-07 Pharmafilm Srl Film orodispersibili a rapida disgregazione per uso terapeutico o alimentare
US10869497B2 (en) 2015-09-08 2020-12-22 R.J. Reynolds Tobacco Company High-pressure cold pasteurization of tobacco material
US10532046B2 (en) 2015-12-03 2020-01-14 Niconovum Usa, Inc. Multi-phase delivery compositions and products incorporating such compositions
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
US10499684B2 (en) 2016-01-28 2019-12-10 R.J. Reynolds Tobacco Company Tobacco-derived flavorants
US11154087B2 (en) 2016-02-02 2021-10-26 R.J. Reynolds Tobacco Company Method for preparing flavorful compounds isolated from black liquor and products incorporating the flavorful compounds
CN109475508A (zh) * 2016-06-07 2019-03-15 阿瑞迪思医药品股份有限责任公司 具有增强的热稳定性的含有生物活性材料的速溶薄膜的制备方法
IL247161A0 (en) * 2016-08-08 2016-12-29 Rubin Yoram Fast-dissolving adhesive films for the treatment of oral conditions
US11091446B2 (en) 2017-03-24 2021-08-17 R.J. Reynolds Tobacco Company Methods of selectively forming substituted pyrazines
PL3720418T3 (pl) 2017-12-08 2021-12-20 Fertin Pharma A/S Tabletka nikotynowa
US20190307082A1 (en) 2018-04-05 2019-10-10 R.J. Reynolds Tobacco Company Oriental tobacco production methods
US11612564B2 (en) * 2018-04-21 2023-03-28 Quest Products, Llc Bilayer adhering lozenge effective to mask undesirable flavor
WO2019239356A1 (en) 2018-06-15 2019-12-19 R. J. Reynolds Tobacco Company Purification of nicotine
WO2019244176A1 (en) * 2018-06-23 2019-12-26 Strides Shasun Limited Stable nicotine lozenges
US11235013B2 (en) 2018-09-04 2022-02-01 Babak Ghalili Cannabinoid, menthol and caffeine dissolvable film compositions, devices and methods
JP7361547B2 (ja) 2019-09-10 2023-10-16 三菱電機ビルソリューションズ株式会社 ロボットシステム
WO2021177941A1 (en) * 2020-03-03 2021-09-10 Babak Ghalili Cannabinoid, menthol and caffeine dissolvable film compositions, devices and methods
EP4326095A1 (en) * 2021-04-22 2024-02-28 Nicoventures Trading Limited Orally dissolving films
WO2024037043A1 (zh) * 2023-04-28 2024-02-22 深圳华宝协同创新技术研究院有限公司 用于口腔粘膜的包含尼古丁的薄膜组合物

Family Cites Families (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288498A (en) 1985-05-01 1994-02-22 University Of Utah Research Foundation Compositions of oral nondissolvable matrixes for transmucosal administration of medicaments
JPH0729915B2 (ja) * 1986-02-01 1995-04-05 帝國製薬株式会社 シ−ト状口腔内貼付剤
JPS62223112A (ja) * 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
DE3827561C1 (pt) * 1988-08-13 1989-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
DE4310012A1 (de) * 1993-03-27 1994-09-29 Roehm Gmbh Dermales therapeutisches System aus einer schmelzfähigen Poly(meth)acrylat-Mischung
AU7323794A (en) * 1993-07-09 1995-02-06 Cygnus Therapeutic Systems Method and device for providing nicotine replacement therapy transdermally/transbuccally
GB9405137D0 (en) 1994-03-16 1994-04-27 Xaar Ltd Improvements relating to pulsed droplet deposition apparatus
AU2703795A (en) * 1994-06-23 1996-01-19 Procter & Gamble Company, The Treatment of nicotine craving and/or smoking withdrawal symptoms with a transdermal or transmucosal composition containing nicotine and caffeine or xanthine
US5508276A (en) * 1994-07-18 1996-04-16 Eli Lilly And Company Duloxetine enteric pellets
AU4657896A (en) 1995-01-19 1996-08-07 Cygnus, Inc. Polyisobutylene adhesives containing high TG tackifier for transdermal devices
JPH08245423A (ja) 1995-03-06 1996-09-24 Shionogi & Co Ltd 水系腸溶性コーティング液
PT906089E (pt) 1996-05-13 2004-01-30 Novartis Consumer Health Sa Sistema de administracao bucal
US6623759B2 (en) * 1996-06-28 2003-09-23 Astrazeneca Ab Stable drug form for oral administration with benzimidazole derivatives as active ingredient and process for the preparation thereof
DE19626045C2 (de) * 1996-06-28 1998-12-03 Klinge Co Chem Pharm Fab Stabile Arzneiform zur oralen Verabreichung, welche Omeprazol als aktiven Wirkstoff enthält, sowie Verfahren zur Herstellung derselben
GB9614902D0 (en) 1996-07-16 1996-09-04 Rhodes John Sustained release composition
DE19646392A1 (de) 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht
DE19653605C2 (de) * 1996-12-20 2002-11-28 Roehm Gmbh Haft- und Bindemittel für dermale oder transdermale Therapiesysteme und dessen Verwendung zur Herstellung eines transdermalen Therapiesystems
EP1001970B1 (en) * 1997-06-25 2007-03-07 Pfizer Inc. Dipeptide derivatives as growth hormone secretagogues
US6197331B1 (en) * 1997-07-24 2001-03-06 Perio Products Ltd. Pharmaceutical oral patch for controlled release of pharmaceutical agents in the oral cavity
US20030176467A1 (en) 1997-09-25 2003-09-18 Sven Andersson Nicotine compositions
JP3460538B2 (ja) 1997-10-08 2003-10-27 救急薬品工業株式会社 速溶性フィルム製剤
US6096340A (en) * 1997-11-14 2000-08-01 Andrx Pharmaceuticals, Inc. Omeprazole formulation
ATE402142T1 (de) * 1998-06-18 2008-08-15 Hoffmann La Roche Verfahren für arylalkylsulfid
US6358060B2 (en) * 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
US6596298B2 (en) * 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
US20030170195A1 (en) * 2000-01-10 2003-09-11 Noven Pharmaceuticals, Inc. Compositions and methods for drug delivery
ES2237415T5 (es) * 1999-01-14 2008-12-16 Noven Pharmaceuticals, Inc. Composiciones dermicas.
US6552024B1 (en) * 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
US6248760B1 (en) * 1999-04-14 2001-06-19 Paul C Wilhelmsen Tablet giving rapid release of nicotine for transmucosal administration
US6264981B1 (en) * 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
US6420473B1 (en) * 2000-02-10 2002-07-16 Bpsi Holdings, Inc. Acrylic enteric coating compositions
US7067116B1 (en) 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
KR100452972B1 (ko) * 2000-05-16 2004-10-14 주식회사 삼양사 경피투여용 하이드로젤 조성물
JP4555436B2 (ja) 2000-06-29 2010-09-29 富士通株式会社 薄膜樹脂基板への樹脂モールド方法及び高周波モジュール
DE10032456A1 (de) * 2000-07-04 2002-01-31 Lohmann Therapie Syst Lts Schnell zerfallende Darreichungsform zur Freisetzung von Wirkstoffen im Mundraum oder in Körperhöhlen
WO2002042981A1 (en) * 2000-11-22 2002-05-30 Ausubel Lawrence M System and method for a dynamic auction with package bidding
US20020131990A1 (en) 2000-11-30 2002-09-19 Barkalow David G. Pullulan free edible film compositions and methods of making the same
US6479076B2 (en) * 2001-01-12 2002-11-12 Izhak Blank Nicotine delivery compositions
DE10110391A1 (de) * 2001-03-03 2002-09-26 Lohmann Therapie Syst Lts Hochflexibles Nikotin transdermales therapeutisches System mit Nikotin als Wirkstoff
WO2002076211A1 (en) * 2001-03-26 2002-10-03 Smithkline Beecham Corporation Nicotine-containing oral dosage form
CA2449415A1 (en) * 2001-04-20 2002-10-31 Lavipharm Laboratories Inc. Intraoral delivery of nicotine for smoking cessation
HUP0400264A2 (hu) 2001-06-22 2004-08-30 Pfizer Products Inc. Alacsony oldékonyságú és/vagy savra érzékeny hatóanyagokat és semlegesített savas polimereket tartalmazó gyógyszerkészítmények és eljárás az előállításukra
US20030118653A1 (en) * 2001-07-06 2003-06-26 Lavipharm Laboratories Inc. Quick dissolving oral mucosal drug delivery device with moisture barrier coating
DE10141652B4 (de) * 2001-08-24 2011-04-07 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System auf der Basis von Polyacrylat-Haftklebern ohne funktionelle Gruppen und seine Verwendung
US20030092724A1 (en) * 2001-09-18 2003-05-15 Huaihung Kao Combination sustained release-immediate release oral dosage forms with an opioid analgesic and a non-opioid analgesic
JP5089840B2 (ja) * 2001-09-25 2012-12-05 救急薬品工業株式会社 ニコチン含有フィルム製剤
ES2311073T3 (es) 2001-09-28 2009-02-01 Mcneil-Ppc, Inc. Forma de dosificacion que tiene un nucleo interno y un revestimiento externo.
US7425292B2 (en) * 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US20040037879A1 (en) * 2001-11-02 2004-02-26 Adusumilli Prasad S. Oral controlled release forms useful for reducing or preventing nicotine cravings
MXPA02011337A (es) 2001-11-16 2003-05-26 Nat Starch Chem Invest Peliculas que contienen almidon.
US20030099691A1 (en) * 2001-11-16 2003-05-29 Susan Lydzinski Films containing starch
DE10224612A1 (de) * 2002-06-04 2003-12-24 Lohmann Therapie Syst Lts Wirkstoffhaltige filmförmige Zubereitungen mit verbesserter chemischer Stabilität, und Verfahren zu deren Herstellung
US20040013752A1 (en) * 2002-07-05 2004-01-22 Wolfson Philip E. Buccal and sublingual mucosally absorbed herbal compositions for relieving nicotine withdrawal symptoms and craving for nicotine and nicotine containing substances
US8268352B2 (en) * 2002-08-05 2012-09-18 Torrent Pharmaceuticals Limited Modified release composition for highly soluble drugs
US8216609B2 (en) * 2002-08-05 2012-07-10 Torrent Pharmaceuticals Limited Modified release composition of highly soluble drugs
US20030049307A1 (en) * 2002-08-15 2003-03-13 Gyurik Robert J. Pharmaceutical composition
DE10256775A1 (de) 2002-12-05 2004-06-24 Lts Lohmann Therapie-Systeme Ag Filmförmige Zubereitungen zur transmucosalen Verabreichung von Nicotin, sowie Verfahren zu deren Herstellung
PT1578422E (pt) 2002-12-20 2007-06-14 Niconovum Ab Material particulado contendo nicotina fisicamente e quimicamente estável
US20040208931A1 (en) 2002-12-30 2004-10-21 Friend David R Fast dissolving films for oral administration of drugs
WO2005004989A2 (en) 2003-07-01 2005-01-20 Todd Maibach Film comprising therapeutic agents
DE10338544B4 (de) * 2003-08-19 2017-08-31 Janssen Pharmaceutica N.V. Buccale Formulierungen des Galanthamins und deren Anwendungen
KR20050048056A (ko) 2003-11-18 2005-05-24 (주)케이비피 경구용 소모 필름 조성물
DE10354894A1 (de) * 2003-11-24 2005-07-07 Hf Arzneimittelforschung Gmbh Orale Formulierungen des Desoxypeganins und deren Anwendungen
US20050181050A1 (en) * 2004-01-28 2005-08-18 Collegium Pharmaceutical, Inc. Dosage forms using drug-loaded ion exchange resins
US20050255048A1 (en) * 2004-05-15 2005-11-17 Collegium Pharmaceutical, Inc. Sprayable formulations for the treatment of acute inflammatory skin conditions
US8907153B2 (en) * 2004-06-07 2014-12-09 Nuvo Research Inc. Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same
EP2457580A1 (en) * 2004-08-25 2012-05-30 The UAB Research Foundation Absorption enhancers for drug administration
US20060046969A1 (en) * 2004-08-25 2006-03-02 Aegis Therapeutics Llc Antibacterial compositions for drug administration
US20060046962A1 (en) * 2004-08-25 2006-03-02 Aegis Therapeutics Llc Absorption enhancers for drug administration
EP1807033B1 (en) * 2004-10-08 2016-07-20 Noven Pharmaceuticals, Inc. Transdermal drug delivery device including an occlusive backing
EP1802276A1 (en) * 2004-10-15 2007-07-04 Pfizer Products Inc. Compositions and methods for intranasal, buccal, sublingual and pulmonary delivery of varenicline
GB0508306D0 (en) 2005-04-25 2005-06-01 Bioprogress Technology Ltd Nicotine dosage forms
JP5000932B2 (ja) * 2005-06-21 2012-08-15 日東電工株式会社 ニコチン含有経皮吸収製剤
EP1993509A2 (en) * 2006-02-17 2008-11-26 Novartis AG Disintegrable oral films
US20070269386A1 (en) * 2006-05-16 2007-11-22 Per Steen New product and use and manufacture thereof
WO2008091588A1 (en) 2007-01-22 2008-07-31 Targacept, Inc. Intranasal, buccal, and sublingual administration of metanicotine analogs
FR2912915B1 (fr) 2007-02-28 2012-11-16 Pf Medicament Film a desintegration rapide pour l'administration buccale de substances actives.
CA2678876C (en) 2007-03-07 2015-11-24 Novartis Ag Orally administrable films
US20080286340A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered nicotine containing products
US20080292683A1 (en) * 2007-05-24 2008-11-27 Monosolrx, Llc. Film shreds and delivery system incorporating same
KR101405930B1 (ko) * 2007-07-05 2014-06-12 엘지전자 주식회사 식기 세척기의 제어방법
US20090081294A1 (en) * 2007-09-26 2009-03-26 Gin Jerry B Sustained release dosage form for lubricating an oral cavity
WO2009045022A2 (en) 2007-10-03 2009-04-09 C.L. Pharm Edible film
KR100905027B1 (ko) * 2007-10-03 2009-06-30 (주)씨엘팜 식용 필름
WO2009073190A1 (en) 2007-12-04 2009-06-11 Swedish Match North America, Inc. Fast dissolving films and coatings for controlled release of flavors, active pharmaceutical ingredients, food substances, and nicotine
AU2008334684A1 (en) 2007-12-11 2009-06-18 Novartis Ag Multi-zone films
JP2012505878A (ja) 2008-10-14 2012-03-08 マクニール アーベー 複数部分口内剤形及びその使用
US20100247586A1 (en) * 2009-03-27 2010-09-30 Andreas Hugerth Multi-Portion Intra-Oral Dosage Form With Organoleptic Properties
KR101074271B1 (ko) * 2009-06-25 2011-10-17 (주)차바이오앤디오스텍 불쾌한 맛을 효과적으로 은폐한 경구용 속용 필름
PL2519225T3 (pl) * 2009-12-30 2015-08-31 Novartis Ag Wytłaczane ze stopu cienkie paski z nikotyną
WO2011134846A1 (en) * 2010-04-27 2011-11-03 Novartis Ag Oral dosage forms
MX2013003306A (es) 2010-09-24 2013-07-29 Univ Rutgers Sistema y composiciones mejorados para la administracion transbucal de farmacos.

Also Published As

Publication number Publication date
AU2004259006A1 (en) 2005-02-03
CL2008002406A1 (es) 2009-01-02
JP2006528636A (ja) 2006-12-21
CA2533577A1 (en) 2005-02-03
JP5572133B2 (ja) 2014-08-13
EP1648421A2 (en) 2006-04-26
DK2446881T3 (da) 2014-06-02
PE20050496A1 (es) 2005-06-12
HUE037508T2 (hu) 2018-09-28
JP2011225620A (ja) 2011-11-10
US20060198873A1 (en) 2006-09-07
HRP20171944T1 (hr) 2018-01-26
CA2533577C (en) 2014-10-21
JP5378270B2 (ja) 2013-12-25
ES2654062T3 (es) 2018-02-12
RU2351315C2 (ru) 2009-04-10
CL2008002407A1 (es) 2009-01-02
JP5038477B2 (ja) 2012-10-03
MXPA06000852A (es) 2006-03-30
AU2004259006B2 (en) 2010-10-07
PL2446881T3 (pl) 2014-08-29
EP2446881A1 (en) 2012-05-02
CN1826117A (zh) 2006-08-30
WO2005009386A2 (en) 2005-02-03
JP2011037879A (ja) 2011-02-24
PT1648421T (pt) 2017-12-22
AU2010224456A1 (en) 2010-10-21
WO2005009386A3 (en) 2005-09-09
AU2010224456B2 (en) 2013-08-29
CN100508976C (zh) 2009-07-08
DK1648421T3 (en) 2017-12-04
AR045076A1 (es) 2005-10-12
RU2008101513A (ru) 2009-07-20
US9675548B2 (en) 2017-06-13
PL1648421T3 (pl) 2018-03-30
LT1648421T (lt) 2018-01-25
EP2446881B1 (en) 2014-04-09
SI1648421T1 (en) 2018-02-28
EP1648421B1 (en) 2017-10-18
BRPI0412752B8 (pt) 2021-05-25
JP2010120975A (ja) 2010-06-03
ES2466943T3 (es) 2014-06-11
BRPI0412752A (pt) 2006-09-26
RU2006105630A (ru) 2006-07-10
TW200514579A (en) 2005-05-01
UY28431A1 (es) 2005-02-28
HK1169802A1 (en) 2013-02-08
AU2010224456B9 (en) 2013-10-24
EP1648421A4 (en) 2009-08-26
BRPI0412752B1 (pt) 2018-07-10

Similar Documents

Publication Publication Date Title
HK1169802A1 (en) Orally dissolving films
EP1641617A4 (en) MULTILAYER FILM
HK1082195A1 (en) Orally-dispersible multilayer tablet
TWI340206B (en) Multi-tiered-recess screws
HK1088602A1 (en) 2-pyridinecarboxamide derivatives
PL378559A1 (pl) Pochodne piperydynobenzenosulfonoamidu
HK1089443A1 (en) Imidazol-4-yl-ethynyl-pyridine derivatives
GB0317665D0 (en) Qinazoline derivatives
PT1682493E (pt) Derivados de aminoacetonitrilo
IL175189A0 (en) N-thiazol-2-yl-benzamide derivatives
AU2003298776A1 (en) Mannose-based fast dissolving tablets
EP1676700A4 (en) MULTILAYER FILM
PT1706373E (pt) Derivados de amidoacetonitrilo
AU2003902882A0 (en) Piperidyl derivatives
EP1676698A4 (en) LAMINATED FILM
GB2404786B (en) Etching films
EP1484066A4 (en) REMEDY FOR INFECTIONS
GB0304759D0 (en) Shutter
GB0329750D0 (en) Camera development
GB0307051D0 (en) Photographic processing
GB0313299D0 (en) Photographic processing
AU154648S (en) Camera
GB0303539D0 (en) Cameras
TWI341309B (en) Heteroarylcarbamoylbenzene derivatives
GB0213888D0 (en) Dielectric films