JP5710269B2 - アザインドリジン類と使用方法 - Google Patents

アザインドリジン類と使用方法 Download PDF

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Publication number
JP5710269B2
JP5710269B2 JP2010539862A JP2010539862A JP5710269B2 JP 5710269 B2 JP5710269 B2 JP 5710269B2 JP 2010539862 A JP2010539862 A JP 2010539862A JP 2010539862 A JP2010539862 A JP 2010539862A JP 5710269 B2 JP5710269 B2 JP 5710269B2
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JP
Japan
Prior art keywords
alkyl
acid
compound
formula
fluoro
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Expired - Fee Related
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JP2010539862A
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Japanese (ja)
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JP2011507896A (ja
JP2011507896A5 (enExample
Inventor
スティーヴン プライス，
スティーヴン プライス，
ロバート ヒールド，
ロバート ヒールド，
ピーター ヒューイット，
ピーター ヒューイット，
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Genentech Inc
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Genentech Inc
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Publication of JP2011507896A publication Critical patent/JP2011507896A/ja
Publication of JP2011507896A5 publication Critical patent/JP2011507896A5/ja
Application granted granted Critical
Publication of JP5710269B2 publication Critical patent/JP5710269B2/ja
Expired - Fee Related legal-status Critical Current
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2010539862A 2007-12-21 2008-12-19 アザインドリジン類と使用方法 Expired - Fee Related JP5710269B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1594207P 2007-12-21 2007-12-21
US61/015,942 2007-12-21
PCT/US2008/087626 WO2009082687A1 (en) 2007-12-21 2008-12-19 Azaindolizines and methods of use

Publications (3)

Publication Number Publication Date
JP2011507896A JP2011507896A (ja) 2011-03-10
JP2011507896A5 JP2011507896A5 (enExample) 2012-01-19
JP5710269B2 true JP5710269B2 (ja) 2015-04-30

Family

ID=40352017

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010539862A Expired - Fee Related JP5710269B2 (ja) 2007-12-21 2008-12-19 アザインドリジン類と使用方法

Country Status (12)

Country Link
US (1) US8486963B2 (enExample)
EP (1) EP2220092B1 (enExample)
JP (1) JP5710269B2 (enExample)
KR (1) KR20100099185A (enExample)
CN (1) CN101945875B (enExample)
AU (1) AU2008340247B2 (enExample)
BR (1) BRPI0819505A2 (enExample)
CA (1) CA2708176A1 (enExample)
ES (1) ES2387707T3 (enExample)
IL (1) IL206125A (enExample)
NZ (1) NZ586575A (enExample)
WO (1) WO2009082687A1 (enExample)

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KR20130118612A (ko) * 2012-04-20 2013-10-30 (주)네오믹스 신규한 아미노피리딘 유도체 및 이의 용도
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WO2015186769A1 (ja) * 2014-06-03 2015-12-10 株式会社ガイア環境技術研究所 食品、医薬品、化粧品及び飼料に利用される非晶質ケイ素、及びその製造方法、製造装置
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ES2913213T3 (es) 2017-05-19 2022-06-01 Nflection Therapeutics Inc Compuestos heteroaromáticos de anilina condensados para el tratamiento de trastornos dérmicos
KR102811888B1 (ko) 2017-09-08 2025-05-27 에프. 호프만-라 로슈 아게 암의 진단 및 치료 방법
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CN113473986B (zh) 2018-11-20 2024-10-11 恩福莱克逊治疗有限公司 用于治疗皮肤疾病萘啶酮苯胺化合物
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CN117157065A (zh) 2021-01-21 2023-12-01 恩福莱克逊治疗有限公司 吡咯并吡啶-苯胺化合物的晶型
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Also Published As

Publication number Publication date
CN101945875B (zh) 2013-04-24
US8486963B2 (en) 2013-07-16
KR20100099185A (ko) 2010-09-10
ES2387707T3 (es) 2012-09-28
IL206125A0 (en) 2010-11-30
AU2008340247B2 (en) 2012-11-15
CN101945875A (zh) 2011-01-12
RU2010130315A (ru) 2012-01-27
AU2008340247A1 (en) 2009-07-02
JP2011507896A (ja) 2011-03-10
IL206125A (en) 2015-08-31
EP2220092B1 (en) 2012-06-06
NZ586575A (en) 2012-03-30
US20110142826A1 (en) 2011-06-16
EP2220092A1 (en) 2010-08-25
CA2708176A1 (en) 2009-07-02
BRPI0819505A2 (pt) 2017-04-04
WO2009082687A1 (en) 2009-07-02

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