JP5710269B2 - アザインドリジン類と使用方法 - Google Patents

アザインドリジン類と使用方法 Download PDF

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Publication number
JP5710269B2
JP5710269B2 JP2010539862A JP2010539862A JP5710269B2 JP 5710269 B2 JP5710269 B2 JP 5710269B2 JP 2010539862 A JP2010539862 A JP 2010539862A JP 2010539862 A JP2010539862 A JP 2010539862A JP 5710269 B2 JP5710269 B2 JP 5710269B2
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JP
Japan
Prior art keywords
alkyl
acid
compound
formula
fluoro
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2010539862A
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English (en)
Japanese (ja)
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JP2011507896A (ja
JP2011507896A5 (enExample
Inventor
スティーヴン プライス，
スティーヴン プライス，
ロバート ヒールド，
ロバート ヒールド，
ピーター ヒューイット，
ピーター ヒューイット，
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Genentech Inc
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Genentech Inc
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Publication of JP2011507896A publication Critical patent/JP2011507896A/ja
Publication of JP2011507896A5 publication Critical patent/JP2011507896A5/ja
Application granted granted Critical
Publication of JP5710269B2 publication Critical patent/JP5710269B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2010539862A 2007-12-21 2008-12-19 アザインドリジン類と使用方法 Expired - Fee Related JP5710269B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1594207P 2007-12-21 2007-12-21
US61/015,942 2007-12-21
PCT/US2008/087626 WO2009082687A1 (en) 2007-12-21 2008-12-19 Azaindolizines and methods of use

Publications (3)

Publication Number Publication Date
JP2011507896A JP2011507896A (ja) 2011-03-10
JP2011507896A5 JP2011507896A5 (enExample) 2012-01-19
JP5710269B2 true JP5710269B2 (ja) 2015-04-30

Family

ID=40352017

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010539862A Expired - Fee Related JP5710269B2 (ja) 2007-12-21 2008-12-19 アザインドリジン類と使用方法

Country Status (12)

Country Link
US (1) US8486963B2 (enExample)
EP (1) EP2220092B1 (enExample)
JP (1) JP5710269B2 (enExample)
KR (1) KR20100099185A (enExample)
CN (1) CN101945875B (enExample)
AU (1) AU2008340247B2 (enExample)
BR (1) BRPI0819505A2 (enExample)
CA (1) CA2708176A1 (enExample)
ES (1) ES2387707T3 (enExample)
IL (1) IL206125A (enExample)
NZ (1) NZ586575A (enExample)
WO (1) WO2009082687A1 (enExample)

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ES2913213T3 (es) 2017-05-19 2022-06-01 Nflection Therapeutics Inc Compuestos heteroaromáticos de anilina condensados para el tratamiento de trastornos dérmicos
KR102642411B1 (ko) 2017-05-19 2024-02-28 엔플렉션 테라퓨틱스, 인코포레이티드 피부병 치료를 위한 피롤로피리딘-아닐린 화합물
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JP7393808B2 (ja) 2018-11-20 2023-12-07 エヌフレクション セラピューティクス インコーポレイテッド 皮膚障害の処置のためのナフチリジノン－アニリン化合物
CN117551073A (zh) 2018-11-20 2024-02-13 恩福莱克逊治疗有限公司 用于治疗皮肤疾病噻吩基苯胺化合物
WO2021094210A1 (en) 2019-11-12 2021-05-20 Bayer Aktiengesellschaft Substituted pyrazine carboxamide derivatives as prostaglandin ep3 receptor antagonists
WO2024033381A1 (en) 2022-08-10 2024-02-15 Vib Vzw Inhibition of tcf4/itf2 in the treatment of cancer

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Also Published As

Publication number Publication date
AU2008340247B2 (en) 2012-11-15
KR20100099185A (ko) 2010-09-10
CN101945875B (zh) 2013-04-24
AU2008340247A1 (en) 2009-07-02
CN101945875A (zh) 2011-01-12
JP2011507896A (ja) 2011-03-10
BRPI0819505A2 (pt) 2017-04-04
US8486963B2 (en) 2013-07-16
WO2009082687A1 (en) 2009-07-02
CA2708176A1 (en) 2009-07-02
RU2010130315A (ru) 2012-01-27
NZ586575A (en) 2012-03-30
ES2387707T3 (es) 2012-09-28
IL206125A0 (en) 2010-11-30
IL206125A (en) 2015-08-31
EP2220092B1 (en) 2012-06-06
EP2220092A1 (en) 2010-08-25
US20110142826A1 (en) 2011-06-16

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