CN101945875B - 氮杂吲嗪及其使用方法 - Google Patents

氮杂吲嗪及其使用方法 Download PDF

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Publication number
CN101945875B
CN101945875B CN2008801273742A CN200880127374A CN101945875B CN 101945875 B CN101945875 B CN 101945875B CN 2008801273742 A CN2008801273742 A CN 2008801273742A CN 200880127374 A CN200880127374 A CN 200880127374A CN 101945875 B CN101945875 B CN 101945875B
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China
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alkyl
formula
acid
compounds
compound
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Expired - Fee Related
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CN2008801273742A
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English (en)
Chinese (zh)
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CN101945875A (zh
Inventor
斯蒂芬·普莱斯
罗伯特·希尔德
彼得·赫维特
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Genentech Inc
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Genentech Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2008801273742A 2007-12-21 2008-12-19 氮杂吲嗪及其使用方法 Expired - Fee Related CN101945875B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1594207P 2007-12-21 2007-12-21
US61/015,942 2007-12-21
PCT/US2008/087626 WO2009082687A1 (en) 2007-12-21 2008-12-19 Azaindolizines and methods of use

Publications (2)

Publication Number Publication Date
CN101945875A CN101945875A (zh) 2011-01-12
CN101945875B true CN101945875B (zh) 2013-04-24

Family

ID=40352017

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008801273742A Expired - Fee Related CN101945875B (zh) 2007-12-21 2008-12-19 氮杂吲嗪及其使用方法

Country Status (12)

Country Link
US (1) US8486963B2 (enExample)
EP (1) EP2220092B1 (enExample)
JP (1) JP5710269B2 (enExample)
KR (1) KR20100099185A (enExample)
CN (1) CN101945875B (enExample)
AU (1) AU2008340247B2 (enExample)
BR (1) BRPI0819505A2 (enExample)
CA (1) CA2708176A1 (enExample)
ES (1) ES2387707T3 (enExample)
IL (1) IL206125A (enExample)
NZ (1) NZ586575A (enExample)
WO (1) WO2009082687A1 (enExample)

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KR20130118612A (ko) * 2012-04-20 2013-10-30 (주)네오믹스 신규한 아미노피리딘 유도체 및 이의 용도
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WO2015186769A1 (ja) * 2014-06-03 2015-12-10 株式会社ガイア環境技術研究所 食品、医薬品、化粧品及び飼料に利用される非晶質ケイ素、及びその製造方法、製造装置
AU2017249229A1 (en) 2016-04-15 2018-10-04 Genentech, Inc. Diagnostic and therapeutic methods for cancer
JP7212956B2 (ja) 2017-05-19 2023-01-26 エヌフレクション セラピューティクス インコーポレイテッド 皮膚障害の処置用のピロロピリジン－アニリン化合物
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KR102811888B1 (ko) 2017-09-08 2025-05-27 에프. 호프만-라 로슈 아게 암의 진단 및 치료 방법
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EP3883552B1 (en) 2018-11-20 2025-04-09 NFlection Therapeutics, Inc. Cyanoaryl-aniline compounds for treatment of dermal disorders
WO2020106305A1 (en) 2018-11-20 2020-05-28 Nflection Therapeutics, Inc. Thienyl-aniline compounds for treatment of dermal disorders
CN113473986B (zh) 2018-11-20 2024-10-11 恩福莱克逊治疗有限公司 用于治疗皮肤疾病萘啶酮苯胺化合物
WO2021094210A1 (en) 2019-11-12 2021-05-20 Bayer Aktiengesellschaft Substituted pyrazine carboxamide derivatives as prostaglandin ep3 receptor antagonists
CN117157065A (zh) 2021-01-21 2023-12-01 恩福莱克逊治疗有限公司 吡咯并吡啶-苯胺化合物的晶型
US20260048075A1 (en) 2022-08-10 2026-02-19 Vib Vzw Inhibition of TCF4/ITF2 in the Treatment of Cancer
WO2026019990A1 (en) 2024-07-18 2026-01-22 Genentech, Inc. Methods of treating cancer with anti-ccr8/anti-cd3 bispecific antibodies

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Also Published As

Publication number Publication date
US8486963B2 (en) 2013-07-16
KR20100099185A (ko) 2010-09-10
ES2387707T3 (es) 2012-09-28
IL206125A0 (en) 2010-11-30
AU2008340247B2 (en) 2012-11-15
CN101945875A (zh) 2011-01-12
RU2010130315A (ru) 2012-01-27
AU2008340247A1 (en) 2009-07-02
JP5710269B2 (ja) 2015-04-30
JP2011507896A (ja) 2011-03-10
IL206125A (en) 2015-08-31
EP2220092B1 (en) 2012-06-06
NZ586575A (en) 2012-03-30
US20110142826A1 (en) 2011-06-16
EP2220092A1 (en) 2010-08-25
CA2708176A1 (en) 2009-07-02
BRPI0819505A2 (pt) 2017-04-04
WO2009082687A1 (en) 2009-07-02

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Granted publication date: 20130424

Termination date: 20161219