JP5537946B2 - Igf−irを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬 - Google Patents
Igf−irを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬 Download PDFInfo
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- JP5537946B2 JP5537946B2 JP2009538410A JP2009538410A JP5537946B2 JP 5537946 B2 JP5537946 B2 JP 5537946B2 JP 2009538410 A JP2009538410 A JP 2009538410A JP 2009538410 A JP2009538410 A JP 2009538410A JP 5537946 B2 JP5537946 B2 JP 5537946B2
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- igf
- protein
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- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
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- A61K38/18—Growth factors; Growth regulators
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- Cell Biology (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86060506P | 2006-11-22 | 2006-11-22 | |
| US60/860,605 | 2006-11-22 | ||
| US87966607P | 2007-01-09 | 2007-01-09 | |
| US60/879,666 | 2007-01-09 | ||
| PCT/US2007/024316 WO2008066752A2 (en) | 2006-11-22 | 2007-11-21 | Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including igf-ir |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010510315A JP2010510315A (ja) | 2010-04-02 |
| JP2010510315A5 JP2010510315A5 (cg-RX-API-DMAC7.html) | 2010-09-02 |
| JP5537946B2 true JP5537946B2 (ja) | 2014-07-02 |
Family
ID=39468472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009538410A Expired - Fee Related JP5537946B2 (ja) | 2006-11-22 | 2007-11-21 | Igf−irを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬 |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US8470332B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP3156415A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5537946B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20090110295A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007325838B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0719597A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2670471A1 (cg-RX-API-DMAC7.html) |
| CO (1) | CO6390070A2 (cg-RX-API-DMAC7.html) |
| IL (1) | IL198872A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2009005466A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008066752A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1711196A4 (en) | 2003-12-05 | 2011-09-14 | Bristol Myers Squibb Co | INHIBITORS OF TYPE-2 VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTORS |
| JP5537946B2 (ja) | 2006-11-22 | 2014-07-02 | ブリストル−マイヤーズ スクイブ カンパニー | Igf−irを含むチロシンキナーゼ受容体に対する改変タンパク質に基づく標的治療薬 |
| WO2008097497A2 (en) * | 2007-02-02 | 2008-08-14 | Adnexus, A Bristol-Myers Squibb R & D Company | Vegf pathway blockade |
| US8680019B2 (en) * | 2007-08-10 | 2014-03-25 | Protelica, Inc. | Universal fibronectin Type III binding-domain libraries |
| US8470966B2 (en) | 2007-08-10 | 2013-06-25 | Protelica, Inc. | Universal fibronectin type III binding-domain libraries |
| US20090176654A1 (en) * | 2007-08-10 | 2009-07-09 | Protelix, Inc. | Universal fibronectin type III binding-domain libraries |
| MX2010004374A (es) | 2007-10-31 | 2010-04-30 | Medimmune Llc | Armazones proteinicos. |
| US9885050B2 (en) | 2007-11-08 | 2018-02-06 | The University Of Chicago | Molecular affinity clamp technology and uses thereof |
| MX2010008874A (es) * | 2008-02-14 | 2010-09-22 | Bristol Myers Squibb Co | Terapeuticos dirigidos a base de proteinas manipuladas que se unen al receptor de factor de crecimiento epidermico. |
| EP2799448A1 (en) | 2008-05-22 | 2014-11-05 | Bristol-Myers Squibb Company | Multivalent fibronectin based scaffold domain proteins |
| AU2009298501A1 (en) | 2008-09-30 | 2010-04-08 | Abbvie Inc. | Improved antibody libraries |
| WO2010060748A1 (en) | 2008-11-03 | 2010-06-03 | Molecular Partners Ag | Binding proteins inhibiting the vegf-a receptor interaction |
| TWI496582B (zh) | 2008-11-24 | 2015-08-21 | 必治妥美雅史谷比公司 | 雙重專一性之egfr/igfir結合分子 |
| EP2379718B2 (en) | 2008-12-16 | 2020-12-30 | Novartis AG | Yeast display systems |
| WO2011051333A1 (en) | 2009-10-30 | 2011-05-05 | Novartis Ag | Universal fibronectin type iii bottom-side binding domain libraries |
| EP2336155A1 (en) | 2009-12-21 | 2011-06-22 | Centre National de la Recherche Scientifique (CNRS) | Antimicrobial peptides |
| EP2533806B1 (en) | 2010-02-10 | 2019-09-04 | Mayo Foundation for Medical Education and Research | Methods and materials for treating cancer |
| MX2012009050A (es) | 2010-02-18 | 2012-09-07 | Squibb Bristol Myers Co | Proteinas de dominio de andamiaje de fibronectina que se unen a interleucina 23 (il-23). |
| EA022983B1 (ru) | 2010-04-13 | 2016-04-29 | Бристол-Майерс Сквибб Компани | Белки на основе структурного домена фибронектина, связывающие pcsk9 |
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| JP2010510315A (ja) | 2010-04-02 |
| BRPI0719597A2 (pt) | 2013-12-17 |
| US20170190761A1 (en) | 2017-07-06 |
| CA2670471A1 (en) | 2008-06-05 |
| WO2008066752A8 (en) | 2009-07-09 |
| US10221232B2 (en) | 2019-03-05 |
| WO2008066752A3 (en) | 2009-03-05 |
| EP2727936B1 (en) | 2016-09-07 |
| IL198872A0 (en) | 2011-08-01 |
| US20130310317A1 (en) | 2013-11-21 |
| KR20090110295A (ko) | 2009-10-21 |
| WO2008066752A2 (en) | 2008-06-05 |
| EP2121743A2 (en) | 2009-11-25 |
| US20190202894A1 (en) | 2019-07-04 |
| US20100121033A1 (en) | 2010-05-13 |
| EP3156415A1 (en) | 2017-04-19 |
| US8470332B2 (en) | 2013-06-25 |
| AU2007325838A2 (en) | 2010-06-24 |
| CO6390070A2 (es) | 2012-02-29 |
| EP2121743B1 (en) | 2015-06-03 |
| MX2009005466A (es) | 2009-08-17 |
| AU2007325838B2 (en) | 2013-09-19 |
| EP2727936A1 (en) | 2014-05-07 |
| US20150252097A1 (en) | 2015-09-10 |
| US11149077B2 (en) | 2021-10-19 |
| AU2007325838A1 (en) | 2008-06-05 |
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