JP5349306B2 - アザベンゾチオフェニル化合物および使用方法 - Google Patents
アザベンゾチオフェニル化合物および使用方法 Download PDFInfo
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- JP5349306B2 JP5349306B2 JP2009525719A JP2009525719A JP5349306B2 JP 5349306 B2 JP5349306 B2 JP 5349306B2 JP 2009525719 A JP2009525719 A JP 2009525719A JP 2009525719 A JP2009525719 A JP 2009525719A JP 5349306 B2 JP5349306 B2 JP 5349306B2
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A61P35/00—Antineoplastic agents
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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| PCT/US2007/076340 WO2008024724A1 (en) | 2006-08-21 | 2007-08-20 | Aza-benzothiophenyl compounds and methods of use |
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| EP (1) | EP2069359B1 (OSRAM) |
| JP (1) | JP5349306B2 (OSRAM) |
| KR (1) | KR101475088B1 (OSRAM) |
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| CA (1) | CA2660963A1 (OSRAM) |
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| NO (1) | NO20091198L (OSRAM) |
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| JP5651125B2 (ja) | 2008-12-10 | 2015-01-07 | デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド | Ｍｅｋ阻害剤に対する耐性を付与するｍｅｋ突然変異 |
| ES2576061T3 (es) | 2010-02-25 | 2016-07-05 | Dana-Farber Cancer Institute, Inc. | Mutaciones de BRAF que confieren resistencia a inhibidores de BRAF |
| EP2545187B1 (en) | 2010-03-09 | 2018-09-05 | Dana-Farber Cancer Institute, Inc. | Methods of diagnosing and treating cancer in patients having or developing resistance to a first cancer therapy |
| CA2871270A1 (en) | 2012-05-02 | 2013-11-07 | Lupin Limited | Substituted pyridine compounds as crac modulators |
| WO2013169858A1 (en) | 2012-05-08 | 2013-11-14 | The Broad Institute, Inc. | Diagnostic and treatment methods in patients having or at risk of developing resistance to cancer therapy |
| EP2916859B1 (en) | 2012-11-02 | 2017-06-28 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Method of reducing adverse effects in a cancer patient undergoing treatment with a mek inhibitor |
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| WO2017180581A1 (en) | 2016-04-15 | 2017-10-19 | Genentech, Inc. | Diagnostic and therapeutic methods for cancer |
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| US10988483B2 (en) | 2017-05-19 | 2021-04-27 | Nflection Therapeutics, Inc. | Fused heteroaromatic-aniline compounds for treatment of dermal disorders |
| JP7514005B2 (ja) | 2017-06-21 | 2024-07-10 | シャイ・セラピューティクス・エルエルシー | がん、炎症性疾患、ラソパシー、及び線維性疾患の治療のためのｒａｓスーパーファミリーと相互作用する化合物 |
| EP3679159A1 (en) | 2017-09-08 | 2020-07-15 | H. Hoffnabb-La Roche Ag | Diagnostic and therapeutic methods for cancer |
| WO2019158579A1 (en) | 2018-02-13 | 2019-08-22 | Vib Vzw | Targeting minimal residual disease in cancer with rxr antagonists |
| WO2020014068A1 (en) | 2018-07-09 | 2020-01-16 | Boehringer Ingelheim Animal Health USA Inc. | Anthelminthic heterocyclic compounds |
| MA55141A (fr) | 2018-11-20 | 2021-09-29 | Nflection Therapeutics Inc | Composés cyanoaryl-aniline pour le traitement d'affections de la peau |
| CA3120337A1 (en) | 2018-11-20 | 2020-05-28 | Nflection Therapeutics, Inc. | Naphthyridinone-aniline compounds for treatment of dermal disorders |
| WO2020106305A1 (en) | 2018-11-20 | 2020-05-28 | Nflection Therapeutics, Inc. | Thienyl-aniline compounds for treatment of dermal disorders |
| EP3898609A1 (en) | 2018-12-19 | 2021-10-27 | Shy Therapeutics LLC | Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease |
| CA3133100A1 (en) | 2019-03-19 | 2020-09-24 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic aza-benzothiophene and aza-benzofuran compounds |
| AU2021278889A1 (en) | 2020-05-29 | 2023-02-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anthelmintic heterocyclic compounds |
| US12371667B2 (en) | 2021-05-13 | 2025-07-29 | Washington University | Enhanced methods for inducing and maintaining naive human pluripotent stem cells |
| UY39995A (es) | 2021-11-01 | 2023-05-15 | Boehringer Ingelheim Vetmedica GmbH | Compuestos de pirrolopiridazina como antihelmínticos |
| WO2024033381A1 (en) | 2022-08-10 | 2024-02-15 | Vib Vzw | Inhibition of tcf4/itf2 in the treatment of cancer |
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| CN101553492A (zh) | 2006-08-31 | 2009-10-07 | 阵列生物制药公司 | Raf抑制剂化合物及其使用方法 |
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- 2007-08-20 KR KR1020097005785A patent/KR101475088B1/ko not_active Expired - Fee Related
- 2007-08-20 JP JP2009525719A patent/JP5349306B2/ja not_active Expired - Fee Related
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Also Published As
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| EP2069359B1 (en) | 2014-11-12 |
| TWI426078B (zh) | 2014-02-11 |
| KR101475088B1 (ko) | 2014-12-23 |
| BRPI0714629A2 (pt) | 2013-05-07 |
| CL2007002431A1 (es) | 2008-03-14 |
| US20080081821A1 (en) | 2008-04-03 |
| IL197060A (en) | 2014-12-31 |
| CA2660963A1 (en) | 2008-02-28 |
| WO2008024724A1 (en) | 2008-02-28 |
| US7893085B2 (en) | 2011-02-22 |
| PE20081359A1 (es) | 2008-11-27 |
| KR20090047538A (ko) | 2009-05-12 |
| JP2010501584A (ja) | 2010-01-21 |
| AU2007286807A1 (en) | 2008-02-28 |
| NO20091198L (no) | 2009-05-20 |
| EP2069359A1 (en) | 2009-06-17 |
| IL197060A0 (en) | 2009-11-18 |
| ES2528797T3 (es) | 2015-02-12 |
| PE20120049A1 (es) | 2012-02-16 |
| AR062469A1 (es) | 2008-11-12 |
| AU2007286807B2 (en) | 2013-03-21 |
| MX2009001875A (es) | 2009-03-02 |
| TW200823222A (en) | 2008-06-01 |
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