JP5276986B2 - 四炭素アルコールの発酵性生産 - Google Patents

四炭素アルコールの発酵性生産 Download PDF

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JP5276986B2
JP5276986B2 JP2008537902A JP2008537902A JP5276986B2 JP 5276986 B2 JP5276986 B2 JP 5276986B2 JP 2008537902 A JP2008537902 A JP 2008537902A JP 2008537902 A JP2008537902 A JP 2008537902A JP 5276986 B2 JP5276986 B2 JP 5276986B2
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seq
host cell
acid
isobutanol
substrate
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JP2009513136A (ja
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ドナルドソン，ゲイル・ケイ
エリオツト，アンドリユー・シー
フリント，デニス
マツジオ−ホール，ロリ・アン
ナガラジヤン，バサンサ
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ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー
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    • C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
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JP2008537902A 2005-10-26 2006-10-25 四炭素アルコールの発酵性生産 Expired - Fee Related JP5276986B2 (ja)

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Application Number Priority Date Filing Date Title
US73029005P 2005-10-26 2005-10-26
US60/730,290 2005-10-26
PCT/US2006/041602 WO2007050671A2 (en) 2005-10-26 2006-10-25 Fermentive production of four carbon alcohols

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JP2009513136A JP2009513136A (ja) 2009-04-02
JP2009513136A5 JP2009513136A5 (https=) 2009-12-17
JP5276986B2 true JP5276986B2 (ja) 2013-08-28

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US (14) US7851188B2 (https=)
EP (2) EP3301182B1 (https=)
JP (1) JP5276986B2 (https=)
CN (1) CN101297042A (https=)
BR (1) BRPI0619325B8 (https=)
CA (1) CA2622026C (https=)
MX (2) MX359740B (https=)
NZ (2) NZ593809A (https=)
RU (1) RU2394913C2 (https=)
UA (3) UA96928C2 (https=)
WO (1) WO2007050671A2 (https=)
ZA (1) ZA200803755B (https=)

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Publication number Priority date Publication date Assignee Title
CA2603774C (en) 2005-04-12 2015-11-17 E.I. Du Pont De Nemours And Company System and process for biomass treatment
US7781191B2 (en) 2005-04-12 2010-08-24 E. I. Du Pont De Nemours And Company Treatment of biomass to obtain a target chemical
US20070029252A1 (en) 2005-04-12 2007-02-08 Dunson James B Jr System and process for biomass treatment
US8945899B2 (en) * 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
US9303225B2 (en) 2005-10-26 2016-04-05 Butamax Advanced Biofuels Llc Method for the production of isobutanol by recombinant yeast
MX359740B (es) * 2005-10-26 2018-10-09 Du Pont Produccion fermentativa de alcoholes de cuatro atomos de carbono.
US8273558B2 (en) 2005-10-26 2012-09-25 Butamax(Tm) Advanced Biofuels Llc Fermentive production of four carbon alcohols
US20080274526A1 (en) * 2007-05-02 2008-11-06 Bramucci Michael G Method for the production of isobutanol
US7309602B2 (en) * 2006-04-13 2007-12-18 Ambrozea, Inc. Compositions and methods for producing fermentation products and residuals
US20090099401A1 (en) 2006-06-16 2009-04-16 D Amore Michael B Process for making isooctenes from aqueous isobutanol
US8673601B2 (en) * 2007-01-22 2014-03-18 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
PL389665A1 (pl) 2007-02-09 2010-07-05 The Regents of the University of CaliforniaThe Regents of the University of California Wytwarzanie biopaliwa przez rekombinowane mikroorganizmy
US20090111154A1 (en) * 2007-04-04 2009-04-30 The Regents Of The University Of California Butanol production by recombinant microorganisms
EP2134849B1 (en) 2007-04-18 2013-07-10 Butamax (TM) Advanced Biofuels LLC Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes
US8026386B2 (en) * 2007-08-10 2011-09-27 Genomatica, Inc. Methods for the synthesis of olefins and derivatives
US8445236B2 (en) 2007-08-22 2013-05-21 Alliance For Sustainable Energy Llc Biomass pretreatment
US7807419B2 (en) 2007-08-22 2010-10-05 E. I. Du Pont De Nemours And Company Process for concentrated biomass saccharification
US7819976B2 (en) 2007-08-22 2010-10-26 E. I. Du Pont De Nemours And Company Biomass treatment method
CL2008002961A1 (es) 2007-10-04 2009-05-08 Bio Arch Lab Inc Metodo para convertir un monosacarido u oligosacarido apropiado en un quimico generico que comprende contactar dichos moleculas con un sistema microbiano que comprende uno o mas genes que codifican y expresan una via de biosintesis.
BRPI0817545A2 (pt) * 2007-10-12 2014-11-25 Univ California Microorganismo recombinante, métodos para produzir um microorganismo recombinante e para produzir isopropanol, vetor recombinante, e, célula hospedeira recombinante.
EP2215243A2 (en) * 2007-10-31 2010-08-11 GEVO, Inc. Methods for the economical production of biofuel precursor that is also a biofuel from biomass
WO2009079213A2 (en) 2007-12-03 2009-06-25 Gevo, Inc. Renewable compositions
US8193402B2 (en) * 2007-12-03 2012-06-05 Gevo, Inc. Renewable compositions
US8114641B2 (en) * 2007-12-10 2012-02-14 Synthetic Genomics, Inc. Methylbutanol as an advanced biofuel
DE102007060705A1 (de) 2007-12-17 2009-06-18 Evonik Degussa Gmbh ω-Aminocarbonsäuren oder ihre Lactame, herstellende, rekombinante Zellen
ES2553726T3 (es) 2007-12-20 2015-12-11 Butamax (Tm) Advanced Biofuels Llc Cetol-ácido reductoisomerasa que utiliza NADH
US20090162911A1 (en) * 2007-12-21 2009-06-25 E.I. Du Pont De Nemours And Company Strain for butanol production
US8372612B2 (en) * 2007-12-21 2013-02-12 Butamax(Tm) Advanced Biofuels Llc Production of four carbon alcohols using improved strain
US8518678B2 (en) * 2007-12-21 2013-08-27 Butamax(Tm) Advanced Biofuels Llc Strain comprising increased expression of a CFA coding region for butanol production
WO2009086423A2 (en) * 2007-12-23 2009-07-09 Gevo, Inc. Yeast organism producing isobutanol at a high yield
US8455239B2 (en) * 2007-12-23 2013-06-04 Gevo, Inc. Yeast organism producing isobutanol at a high yield
MY153731A (en) 2007-12-27 2015-03-13 Gevo Inc Recovery of higher alcohols from dilute aqueous solutions
CA2712779C (en) 2008-01-22 2021-03-16 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
DE102008010121B4 (de) * 2008-02-20 2013-11-21 Butalco Gmbh Fermentative Produktion von Isobutanol mit Hefe
US9259662B2 (en) 2008-02-22 2016-02-16 James Weifu Lee Photovoltaic panel-interfaced solar-greenhouse distillation systems
US10093552B2 (en) 2008-02-22 2018-10-09 James Weifu Lee Photovoltaic panel-interfaced solar-greenhouse distillation systems
DK2250276T3 (en) * 2008-02-23 2017-02-13 James Weifu Lee DESIGN ORGANISMS FOR PHOTOBIOLOGICAL PRODUCTION OF BUTANOL FROM CARBON DIOXIDE AND WATER
EP2250273B1 (en) * 2008-02-28 2016-04-13 Green Biologics Limited Enzymatic production of C4-C8 alcohols and acids
DK2262901T3 (en) 2008-03-05 2019-01-21 Genomatica Inc ORGANISMS PRODUCING PRIMARY ALCOHOL
TW202306945A (zh) 2008-03-11 2023-02-16 美商吉諾瑪蒂卡股份有限公司 由α-酮庚二酸製備6-胺己酸之技術
JP5444323B2 (ja) * 2008-03-27 2014-03-19 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 高発現ザイモモナス（Ｚｙｍｏｍｏｎａｓ）プロモーター
ES2656790T3 (es) 2008-03-27 2018-02-28 Genomatica, Inc. Microorganismos para la producción de ácido adípico y otros compuestos
JP2011515107A (ja) * 2008-03-27 2011-05-19 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 改善されたキシロース資化能を有するザイモモナス（Ｚｙｍｏｍｏｎａｓ）
GB0806093D0 (en) * 2008-04-03 2008-05-14 Green Biologics Ltd Production of butanol
US8188250B2 (en) * 2008-04-28 2012-05-29 Butamax(Tm) Advanced Biofuels Llc Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans
WO2009135074A2 (en) 2008-05-01 2009-11-05 Genomatica, Inc. Microorganisms for the production of methacrylic acid
US8389252B2 (en) * 2008-05-12 2013-03-05 Butamax(Tm) Advanced Biofuels Llc Yeast strain for production of four carbon alcohols
WO2009143455A2 (en) 2008-05-22 2009-11-26 Microbia, Inc. Engineering resistance to aliphatic alcohols
AU2009256148B2 (en) * 2008-06-04 2014-11-27 Butamax(Tm) Advanced Biofuels Llc A method for producing butanol using two-phase extractive fermentation
WO2009149240A1 (en) * 2008-06-04 2009-12-10 E. I. Du Pont De Nemours And Company Deletion mutants for the production of isobutanol
US8828695B2 (en) * 2008-06-04 2014-09-09 Butamax Advanced Biofuels Llc Method for producing butanol using two-phase extractive fermentation
BRPI0909989A2 (pt) 2008-06-05 2021-06-22 Butamax Advanced Biofuels Llc célula de levedura recombinante e método para a produção de um produto
BRPI0913901A2 (pt) * 2008-06-17 2016-12-13 Genomatica Inc micro-organismos e métodos para a biossíntese de fumarato, malato e acrilato
US20100021978A1 (en) * 2008-07-23 2010-01-28 Genomatica, Inc. Methods and organisms for production of 3-hydroxypropionic acid
WO2010017230A2 (en) * 2008-08-04 2010-02-11 The Regents Of The University Of Colorado Methods, systems and compositions related to microbial bio-production of butanol and/or isobutanol
WO2010031772A2 (en) * 2008-09-16 2010-03-25 Dsm Ip Assets B.V. Alternative butanol production process in a microbial cell
CA2736420A1 (en) * 2008-09-29 2010-04-01 Butamaxtm Advanced Biofuels Llc Enhanced dihydroxy-acid dehydratase activity in lactic acid bacteria
US9206447B2 (en) 2008-09-29 2015-12-08 Butamax Advanced Biofuels Llc Recombinant yeast host cells comprising FE-S cluster proteins
US20160222370A1 (en) * 2008-09-29 2016-08-04 Butamax Advanced Biofuels Llc Recombinant Yeast Host Cell With Fe-S Cluster Proteins And Methods Of Using Thereof
WO2010037119A1 (en) * 2008-09-29 2010-04-01 Butamax™ Advanced Biofuels LLC Enhanced iron-sulfur cluster formation for increased dihydroxy-acid dehydratase activity in lactic acid bacteria
MX2011003238A (es) * 2008-09-29 2011-04-28 Butamax Tm Advanced Biofuels Identificacion y uso de dihidroxiacido deshidratasas [2fe-2s] bacterianas.
AU2009296227A1 (en) * 2008-09-29 2010-04-01 Butamax(Tm) Advanced Biofuels Llc Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria
CA2737112A1 (en) * 2008-10-27 2010-06-03 Butamax Advanced Biofuels Llc Carbon pathway optimized production hosts for the production of isobutanol
WO2010062707A1 (en) * 2008-10-30 2010-06-03 Joule Unlimited, Inc. Methods and compositions for producing carbon-based products of interest in micro-organisms
CA2779262C (en) * 2008-10-31 2021-09-07 Gevo, Inc. Engineered microorganisms capable of converting pyruvate to isobutanol under anaerobic conditions
US8828694B2 (en) * 2008-11-13 2014-09-09 Butamax Advanced Biofuels Llc Production of isobutanol in yeast mitochondria
US8465964B2 (en) 2008-11-13 2013-06-18 Butamax (TM) Advanced Biofules LLC Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis
WO2010057022A1 (en) * 2008-11-14 2010-05-20 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
US8652823B2 (en) * 2008-12-03 2014-02-18 Butamax(Tm) Advanced Biofuels Llc Strain for butanol production with increased membrane unsaturated trans fatty acids
US20100144000A1 (en) * 2008-12-04 2010-06-10 E. I. Du Pont De Nemours And Company Process for fermentive preparation fo alcohols and recovery of product
US20100140166A1 (en) * 2008-12-04 2010-06-10 E.I. Du Pont De Nemours And Company Process for fermentive preparation of alcohols and recovery of product
US20100143993A1 (en) * 2008-12-04 2010-06-10 E.I. Du Pont De Nemours And Company Process for fermentive preparationfor alcolhols and recovery of product
US20100143992A1 (en) * 2008-12-04 2010-06-10 E. I Du Pont De Nemours And Company Process for Fermentive Preparation of Alcohols and Recovery of Product
US20100143995A1 (en) 2008-12-04 2010-06-10 E. I. Du Pont De Nemours And Company Process for Fermentive Preparation of Alcohols and Recovery of Product
US20100143999A1 (en) * 2008-12-04 2010-06-10 E.I. Du Pont De Nemours And Company Process for fermentive preparation of alcohols and recovery of product
US20100139154A1 (en) * 2008-12-04 2010-06-10 E.I. Du Pont De Nemours And Company Process for fermentive preparation of alcohols and recovery of product
US20100143994A1 (en) * 2008-12-04 2010-06-10 E. I. Du Pont De Memours And Company Process for fermentive preparation of alcohols and recovery of product
WO2010068821A1 (en) 2008-12-10 2010-06-17 Synthetic Genomics, Inc. Production of branched-chain alcohols by photosynthetic microoraganisms
EP2373781A4 (en) 2008-12-16 2012-10-10 Genomatica Inc MICRO-ORGANISMS AND METHODS OF CONVERTING SYNGAS AND OTHER CARBON RESOURCES IN USEFUL PRODUCTS
WO2010080489A1 (en) * 2008-12-19 2010-07-15 E. I. Du Pont De Nemours And Company Ozone treatment of biomass to enhance enzymatic saccharification
WO2010071851A2 (en) * 2008-12-20 2010-06-24 The Regents Of University Of California Conversion of co2 to higher alcohols using photosysnthetic microorganisms
US8795992B2 (en) * 2008-12-29 2014-08-05 Butamax Advanced Biofuels Llc Yeast with increased butanol tolerance involving cell wall integrity pathway
US8557562B2 (en) * 2008-12-29 2013-10-15 Butamax(Tm) Advanced Biofuels Llc Yeast with increased butanol tolerance involving filamentous growth response
US8455225B2 (en) * 2008-12-29 2013-06-04 Butamax Advanced Biofuels Llc Yeast with increased butanol tolerance involving high osmolarity/glycerol response pathway
RU2405826C2 (ru) 2008-12-29 2010-12-10 Дэвон Инвестмент Лимитед Способ получения органических растворителей, установка для его осуществления, продукт, полученный описанным способом
RU2405828C2 (ru) 2009-01-29 2010-12-10 Дэвон Инвестмент Лимитед Способ получения органических растворителей
BRPI1008287A2 (pt) * 2009-02-24 2016-03-15 Gevo Inc métodos de preparação de butadieno e isopreno renováveis
US8614085B2 (en) 2009-02-27 2013-12-24 Butamax(Tm) Advanced Biofuels Llc Yeast with increased butanol tolerance involving a multidrug efflux pump gene
EP2415860A4 (en) * 2009-03-30 2012-09-05 Res Inst Innovative Tech Earth TRANSFORMANT CORYNEFORMER BACTERIA AND PROCESS FOR ISOBUTANOL PRODUCTION THEREWITH
US8178329B2 (en) 2009-04-01 2012-05-15 Richard Allen Kohn Process to produce organic compounds from synthesis gases
BRPI1006492A2 (pt) * 2009-04-13 2019-09-24 Butamax Advanced Biofuels Llc método para a recuperação de butanol a partir de um meio de fermentação, método para a produção de butanol e mistura de duas fases
MY176050A (en) * 2009-04-30 2020-07-22 Genomatica Inc Organisms for the production of 1,3-butanediol
BRPI1013505A2 (pt) 2009-04-30 2018-02-14 Genomatica Inc organismos para a produção de isopropanol, n-butanol, e isobutanol
EP2427544B1 (en) 2009-05-07 2019-07-17 Genomatica, Inc. Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid
JP2012526561A (ja) * 2009-05-15 2012-11-01 ゲノマチカ， インク． シクロヘキサノンの産生のための生物
EP2440669A4 (en) * 2009-06-10 2013-08-28 Genomatica Inc MICROOGANISMS AND PROCEDURES FOR THE CARBON EFFECTIVE BIOSYNTHESIS MEK AND 2-BUTANOL
EP2446043A4 (en) * 2009-06-22 2013-02-13 Gevo Inc YEAST ORGANISMS FOR THE MANUFACTURE OF ISOBUTANOL
US8968523B2 (en) * 2009-07-15 2015-03-03 Butamax Advanced Biofuels Llc Recovery of butanol isomers from a mixture of butanol isomers, water, and an organic extractant
US8968522B2 (en) * 2009-07-15 2015-03-03 Butamax Advanced Biofuels Llc Recovery of butanol isomers from a mixture of butanol isomers, water, and an organic extractant
EP2277989A1 (en) 2009-07-24 2011-01-26 Technische Universiteit Delft Fermentative glycerol-free ethanol production
EP3190174A1 (en) 2009-08-05 2017-07-12 Genomatica, Inc. Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
BR112012003241A2 (pt) * 2009-08-12 2015-09-01 Gevo Inc Localização de via de isobutanol citosólico para a produção de isobutanol
US8715971B2 (en) 2009-09-09 2014-05-06 Genomatica, Inc. Microorganisms and methods for the co-production of isopropanol and 1,4-butanediol
AU2010300722A1 (en) * 2009-09-29 2012-04-12 Butamax(Tm) Advanced Biofuels Llc Improved flux to acetolactate-derived products in lactic acid bacteria
EP2483401B1 (en) 2009-09-29 2017-06-21 Butamax (TM) Advanced Biofuels LLC Improved yeast production host cells
AU2010300642B2 (en) 2009-09-29 2015-05-14 Butamax(Tm) Advanced Biofuels Llc Fermentive production of isobutanol using highly effective ketol-acid reductoisomerase enzymes
SG10201408071TA (en) * 2009-10-06 2015-01-29 Gevo Inc Integrated process to selectively convert renewable isobutanol to p-xylene
US20110195505A1 (en) * 2009-10-08 2011-08-11 Butamax(Tm) Advanced Biofuels Llc Bacterial strains for butanol production
KR20120083908A (ko) 2009-10-13 2012-07-26 게노마티카 인코포레이티드 1,4-부탄다이올, 4-하이드록시부탄알, 4-하이드록시부티릴-ｃｏａ, 푸트레신 및 관련 화합물의 제조를 위한 미생물 및 관련 방법
KR20180014240A (ko) 2009-10-23 2018-02-07 게노마티카 인코포레이티드 아닐린의 제조를 위한 미생물
US8373008B2 (en) 2009-11-23 2013-02-12 Butamax (Tm) Advanced Biofuels Llc Recovery of butanol from a mixture of butanol, water, and an organic extractant
US8373009B2 (en) * 2009-11-23 2013-02-12 Butamax (Tm) Advanced Biofuels Llc Recovery of butanol from a mixture of butanol, water, and an organic extractant
BR112012012211A2 (pt) 2009-11-23 2017-05-09 Butamax (Tm) Advanced Biofuels Llc método para a recuperação de butanol e método para a produção de butanol
CA2779884A1 (en) 2009-11-23 2011-05-26 Butamax(Tm) Advanced Biofuels Llc Method for producing butanol using extractive fermentation with electrolyte addition
WO2011066356A1 (en) * 2009-11-24 2011-06-03 Gevo, Inc. Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids
US20110137088A1 (en) * 2009-12-03 2011-06-09 Bp Corporation North America Inc. Methods and Apparatuses for Producing Renewable Materials From Inhibiting Compounds
KR20120120493A (ko) 2009-12-10 2012-11-01 게노마티카 인코포레이티드 합성 가스 또는 기타 가스상 탄소원 및 메탄올을 1,3-부탄디올로 변환하는 방법 및 변환용 유기체
WO2011073250A2 (en) 2009-12-15 2011-06-23 Stratley Ag Method for recovery of organic components from dilute aqueous solutions
US9272965B2 (en) * 2009-12-22 2016-03-01 Catalytic Distillation Technologies Process for the conversion of alcohols to olefins
NZ600509A (en) 2009-12-29 2014-08-29 Butamax Tm Advanced Biofuels Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols
NZ600585A (en) 2009-12-29 2014-07-25 Butamax Tm Advanced Biofuels Expression of hexose kinase in recombinant host cells
BR112012016883A2 (pt) 2010-01-08 2018-06-05 Gevo Inc metodos integrados de preparar produsot quimicos renovaveis
JP2013517796A (ja) 2010-01-29 2013-05-20 ジェノマティカ・インコーポレイテッド ｐ−トルイル酸およびテレフタル酸を生合成するための方法および微生物
US8574406B2 (en) 2010-02-09 2013-11-05 Butamax Advanced Biofuels Llc Process to remove product alcohol from a fermentation by vaporization under vacuum
MX2012009362A (es) 2010-02-12 2013-05-28 Gevo Inc Microorganismos de levadura con acumulación reducida de subproductos para una producción mejorada de combustibles, químicos y aminoácidos.
PH12012501658A1 (en) * 2010-02-17 2023-04-28 Butamax Tm Advanced Biofuels Improving activity of fe-s cluster requiring proteins
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US8445244B2 (en) * 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US8906235B2 (en) 2010-04-28 2014-12-09 E I Du Pont De Nemours And Company Process for liquid/solid separation of lignocellulosic biomass hydrolysate fermentation broth
US8721794B2 (en) 2010-04-28 2014-05-13 E I Du Pont De Nemours And Company Production of high solids syrup from lignocellulosic biomass hydrolysate fermentation broth
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
CA2797409C (en) 2010-05-05 2019-12-24 Genomatica, Inc. Microorganisms and methods for the biosynthesis of butadiene
US8373012B2 (en) 2010-05-07 2013-02-12 Gevo, Inc. Renewable jet fuel blendstock from isobutanol
WO2011143215A2 (en) 2010-05-10 2011-11-17 Catalytic Distillation Technologies Production of jet and other heavy fuels from isobutanol
EP2575499A2 (en) 2010-05-31 2013-04-10 Vib Vzw The use of transporters to modulate flavor production by yeast
CN102947425B (zh) 2010-06-16 2015-10-21 布特马斯先进生物燃料有限责任公司 具有良好运转性能的充氧丁醇汽油组合物
WO2011159901A1 (en) 2010-06-16 2011-12-22 Butamax(Tm) Advanced Biofuels Llc Oxygenated butanol gasoline composition having good driveability performance
CA2801576A1 (en) * 2010-06-17 2011-12-22 Butamax(Tm) Advanced Biofuels Llc Yeast production culture for the production of butanol
US8871488B2 (en) 2010-06-18 2014-10-28 Butamax Advanced Biofuels Llc Recombinant host cells comprising phosphoketolases
US9012190B2 (en) * 2011-06-15 2015-04-21 Butamax Advanced Biofuels Llc Use of thiamine and nicotine adenine dinucleotide for butanol production
BR112012032172A2 (pt) 2010-06-18 2015-11-24 Butamax Tm Advanced Biofuels método para produzir um álcool e composição
CN102947457B (zh) 2010-06-18 2016-12-21 布特马斯先进生物燃料有限责任公司 用于在丁醇生产中的提取发酵之前移除不溶解固体的方法和体系
US9040263B2 (en) 2010-07-28 2015-05-26 Butamax Advanced Biofuels Llc Production of alcohol esters and in situ product removal during alcohol fermentation
SG10201504733XA (en) 2010-07-12 2015-07-30 Univ Gent Metabolically engineered organisms for the production of added value bio-products
US8651403B2 (en) 2010-07-21 2014-02-18 E I Du Pont De Nemours And Company Anhydrous ammonia treatment for improved milling of biomass
PH12013500158A1 (en) 2010-07-26 2013-03-11 Genomatica Inc Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
CA2807930A1 (en) 2010-09-02 2012-03-08 Butamax (Tm) Advanced Buofuels Llc Process to remove product alcohol from a fermentation by vaporization under vacuum
WO2012033832A2 (en) * 2010-09-07 2012-03-15 Butamax(Tm) Advanced Biofuels Llc Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion
CA2811394A1 (en) 2010-09-20 2012-03-29 Butamax (Tm) Advanced Biofuels Llc Multimedia evaluation of butanol-containing fuels
KR101381048B1 (ko) * 2010-10-20 2014-04-14 씨제이제일제당 (주) Ｏ-포스포세린 생산 균주 및 이로부터 생산된 ｏ-포스포세린으로부터 ｌ-시스테인 또는 이의 유도체의 생산방법
CN103314101B (zh) 2010-11-03 2016-05-18 加利福尼亚大学董事会 通过蛋白质生物质发酵的重组微生物的生物燃料和化学生产
US20120125551A1 (en) 2010-11-23 2012-05-24 E. I. Du Pont De Nemours And Company Biomass pretreatment process for a packed bed reactor
US20120125548A1 (en) 2010-11-23 2012-05-24 E. I. Du Pont De Nemours And Company Continuously fed biomass pretreatment process for a packed bed reactor
WO2012071121A1 (en) * 2010-11-24 2012-05-31 Gevo, Inc. Methods of increasing dihydroxy acid dehydratase activity to improve production of fuels, chemicals, and amino acids
US20130040340A1 (en) 2011-02-07 2013-02-14 E. I. Du Pont De Nemours And Company Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms
BR112013021524A2 (pt) * 2011-02-25 2017-06-13 Lanzatech New Zealand Ltd micro-organismos recombinantes e usos dos mesmos
WO2012122465A2 (en) * 2011-03-09 2012-09-13 Gevo, Inc. Yeast microorganisms with reduced 2,3-butanediol accumulation for improved production of fuels, chemicals, and amino acids
US9206443B2 (en) 2011-03-14 2015-12-08 Easel Biotechnologies, Llc Microbial synthesis of aldehydes and corresponding alcohols
US8765425B2 (en) 2011-03-23 2014-07-01 Butamax Advanced Biofuels Llc In situ expression of lipase for enzymatic production of alcohol esters during fermentation
US8759044B2 (en) 2011-03-23 2014-06-24 Butamax Advanced Biofuels Llc In situ expression of lipase for enzymatic production of alcohol esters during fermentation
MX347976B (es) 2011-03-24 2017-05-22 Butamax(Tm) Advanced Biofuels Llc Celulas huesped y metodos para producir isobutanol.
EP2508597A1 (en) 2011-04-05 2012-10-10 Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung (IPK) Production of butanol by fermentation in Arxula sp.
US8795996B2 (en) * 2011-04-06 2014-08-05 Wisconsin Alumni Research Foundation Genes related to xylose fermentation and methods of using same for enhanced biofuel production
WO2012145495A2 (en) 2011-04-19 2012-10-26 Gevo, Inc. Variations on prins-like chemistry to produce 2,5-dimethylhexadiene from isobutanol
CA2837722A1 (en) 2011-06-17 2012-12-20 Butamax Advanced Biofuels Llc Co-products from biofuel production processes and methods of making
CA2838519A1 (en) 2011-06-17 2012-12-20 Butamax Advanced Biofuels Llc Lignocellulosic hydrolysates as feedstocks for isobutanol fermentation
WO2013016717A2 (en) 2011-07-28 2013-01-31 Butamax(Tm) Advanced Biofuels Llc Keto-isovalerate decarboxylase enzymes and methods of use thereof
WO2013016724A2 (en) * 2011-07-28 2013-01-31 Gevo, Inc. Decarboxylase proteins with high keto-isovalerate decarboxylase activity
US20130180164A1 (en) 2011-07-28 2013-07-18 Butamax(Tm) Advanced Biofuels Llc Low sulfur fuel compositions having improved lubricity
WO2013033604A2 (en) * 2011-08-31 2013-03-07 The Trustees Of Dartmouth College Production of butanols in thermophilic organisms
JP6133010B2 (ja) * 2011-09-16 2017-05-24 協和発酵バイオ株式会社 アミノ酸の製造法
MX2014003212A (es) 2011-09-16 2015-03-19 Genomatica Inc Microorganismos y metodos para producir alquenos.
EP2578559A1 (en) * 2011-10-07 2013-04-10 Metabolic Explorer Process for producing isobutene from isobutylamine
EP2583957A1 (de) 2011-10-18 2013-04-24 LANXESS Deutschland GmbH Lineare Butene aus Isobutanol
JP5803563B2 (ja) 2011-10-24 2015-11-04 トヨタ自動車株式会社 イソブタノールの製造方法
CA2854450C (en) 2011-11-03 2020-04-21 Easel Biotechnologies, Llc Microbial production of n-butyraldehyde
JP2015501643A (ja) 2011-12-09 2015-01-19 ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー 発酵ブロスから生成物アルコールを取り出す方法
CA2861613A1 (en) 2011-12-30 2013-07-04 Butamax Advanced Biofuels Llc Fermentative production of alcohols
CA2862450A1 (en) 2011-12-30 2013-07-04 Butamax Advanced Biofuels Llc Genetic switches for butanol production
KR20140116175A (ko) 2011-12-30 2014-10-01 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 함산소 가솔린용 부식 억제제 조성물
US9689004B2 (en) * 2012-03-23 2017-06-27 Butamax Advanced Biofuels Llc Acetate supplemention of medium for butanologens
EP2844730A1 (en) 2012-05-04 2015-03-11 Butamax Advanced Biofuels LLC Processes and systems for alcohol production and recovery
NZ701099A (en) * 2012-05-11 2017-04-28 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase enzymes and methods of use
US20140024064A1 (en) 2012-07-23 2014-01-23 Butamax(Tm) Advanced Biofuels Llc Processes and systems for the production of fermentative alcohols
US9605281B2 (en) 2012-09-12 2017-03-28 Butamax Advanced Biofuels Llc Processes and systems for the fermentative production of alcohols
AU2013295626B2 (en) 2012-07-26 2018-02-01 Butamax Advanced Biofuels Llc Butanol purification
MX2015001780A (es) 2012-08-10 2015-09-28 Opx Biotechnologies Inc Microorganismos y métodos para la producción de ácidos grasos y productos derivados de ácidos grasos.
EP2885415B1 (en) 2012-08-17 2022-08-03 Easel Biotechnologies LLC Two stage production of higher alcohols
BR112015003701A2 (pt) 2012-08-22 2017-12-12 Butamax Advanced Biofuels Llc células hospedeiras recombinantes, método para aprimoramento, processo para a produção de um álcool, polinucleotídeo isolado, cassete de expressão e composição
BR112015005439A8 (pt) 2012-09-12 2022-01-11 Butamax Advanced Biofuels Llc Método para recuperar um produto alcoólico de um caldo de fermentação e sistema
US9109196B2 (en) 2012-09-12 2015-08-18 Butamax Advanced Biofuels Llc Processes and systems for the production of fermentation products
BR112015006296A2 (pt) * 2012-09-21 2017-07-04 Butamax Advanced Biofuels Llc ''processo, composição bifásica, métodos para a manutenção do estado oxidativo de uma composição, para otimizar a extração do butanol, para aprimorar o rendimento de uma fermetanção de isobutanol, para aprimorar o título de isobutanol produzido durante a fermentação e para aprimorar a taxa de produção de isobutanol durante uma fermentação''
US9840724B2 (en) 2012-09-21 2017-12-12 Butamax Advanced Biofuels Llc Production of renewable hydrocarbon compositions
WO2014052670A1 (en) 2012-09-26 2014-04-03 Butamax (Tm) Advanced Biofuels Llc Polypeptides with ketol-acid reductoisomerase activity
US20140093931A1 (en) * 2012-09-28 2014-04-03 Butamax Advanced Biofuels Llc Production of fermentation products
US9273330B2 (en) 2012-10-03 2016-03-01 Butamax Advanced Biofuels Llc Butanol tolerance in microorganisms
BR112015008077A2 (pt) 2012-10-11 2017-12-05 Butamax Advanced Biofuels Llc métodos para a produção de um produto de fermentação
US9914672B2 (en) 2012-10-19 2018-03-13 Lummus Technology Inc. Conversion of alcohols to distillate fuels
WO2014081848A1 (en) 2012-11-20 2014-05-30 Butamax Advanced Biofuels Llc Butanol purification
WO2014086780A2 (en) 2012-12-07 2014-06-12 Global Bioenergies Improved fermentation method
CN103409332A (zh) * 2012-12-14 2013-11-27 北京工商大学 产β-苯乙醇的酿酒酵母工程菌构建、菌株及其应用
US20140178954A1 (en) 2012-12-20 2014-06-26 E I Du Pont De Nemours And Company Expression of xylose isomerase activity in yeast
US9650624B2 (en) 2012-12-28 2017-05-16 Butamax Advanced Biofuels Llc DHAD variants for butanol production
WO2014105840A1 (en) 2012-12-31 2014-07-03 Butamax Advanced Biofuels Llc Fermentative production of alcohols
US9469860B2 (en) 2013-01-18 2016-10-18 Synata Bio, Inc. Method for production of n-butanol from syngas using syntrophic co-cultures of anaerobic microorganisms
AU2014209101A1 (en) * 2013-01-25 2015-09-17 Michael Connor Recombinant synthesis of alkanes
US9034629B2 (en) 2013-01-25 2015-05-19 Joule Unlimited Technologies, Inc. Recombinant synthesis of medium chain-length alkanes
US20160002131A1 (en) 2013-02-21 2016-01-07 Butamax Advanced Biofuels Llc Vapor recompression
US8669076B1 (en) 2013-03-11 2014-03-11 E I Du Pont De Nemours And Company Cow rumen xylose isomerases active in yeast cells
US9187743B2 (en) 2013-03-11 2015-11-17 E I Du Pont De Nemours And Company Bacterial xylose isomerases active in yeast cells
US20140273105A1 (en) 2013-03-12 2014-09-18 E I Du Pont De Nemours And Company Gradient pretreatment of lignocellulosic biomass
US9523104B2 (en) 2013-03-12 2016-12-20 Butamax Advanced Biofuels Llc Processes and systems for the production of alcohols
US9441250B2 (en) 2013-03-14 2016-09-13 Butamax Advanced Biofuels Llc Glycerol 3- phosphate dehydrogenase for butanol production
US9267158B2 (en) 2013-03-14 2016-02-23 Intrexon Corporation Biological production of multi-carbon compounds from methane
US9156760B2 (en) 2013-03-15 2015-10-13 Butamax Advanced Biofuels Llc Method for production of butanol using extractive fermentation
WO2014144643A1 (en) 2013-03-15 2014-09-18 Butamax Advanced Biofuels Llc Method for producing butanol using extractive fermentation
US9580705B2 (en) 2013-03-15 2017-02-28 Butamax Advanced Biofuels Llc DHAD variants and methods of screening
US20150119601A1 (en) 2013-03-15 2015-04-30 Opx Biotechnologies, Inc. Monofunctional mcr + 3-hp dehydrogenase
WO2014144210A2 (en) 2013-03-15 2014-09-18 Butamax Advanced Biofuels Llc Competitive growth and/or production advantage for butanologen microorganism
WO2014151645A1 (en) 2013-03-15 2014-09-25 Butamax Advanced Biofuels Llc Process for maximizing biomass growth and butanol yield by feedback control
US9469584B2 (en) 2013-03-15 2016-10-18 Butamax Advanced Biofuels Llc Method for producing butanol using extractive fermentation
GB201315475D0 (en) 2013-08-30 2013-10-16 Green Biologics Ltd Solvent production
WO2015002913A1 (en) 2013-07-03 2015-01-08 Butamax Advanced Biofuels Llc Partial adaptation for butanol production
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
KR20150010904A (ko) * 2013-07-19 2015-01-29 삼성전자주식회사 부티르알데히드 데히드로게나제 변이체, 상기 변이체를 코딩하는 폴리뉴클레오티드, 상기 폴리뉴클레오티드를 포함하는 벡터, 미생물, 및 이를 이용한 1,4-부탄디올의 생산 방법
BR112016009416A2 (pt) 2013-10-28 2017-10-03 Danisco Us Inc Levedura seca ativa geneticamente modificada de grande escala
US10227623B2 (en) 2013-11-24 2019-03-12 E I Du Pont De Nemours And Company High force and high stress destructuring of cellulosic biomass
EP2944697A1 (en) 2014-05-13 2015-11-18 Evonik Degussa GmbH Method of producing nylon
CN104195125B (zh) * 2014-07-01 2017-01-11 中国科学院广州能源研究所 一种α-酮酸脱羧酶KIVD-LL及其编码基因和应用
WO2016007350A1 (en) 2014-07-09 2016-01-14 Danisco Us Inc. Preconditioning of lignocellulosic biomass
EP3180440A4 (en) 2014-08-11 2018-01-10 Butamax Advanced Biofuels LLC Yeast preparations and methods of making the same
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
WO2016089521A1 (en) * 2014-12-04 2016-06-09 Becton, Dickinson And Company Flow cytometry cell sorting systems and methods of using the same
EP3050966A1 (en) * 2015-01-28 2016-08-03 Evonik Degussa GmbH An aerobic method of producing alcohols
MY195498A (en) 2015-06-10 2023-01-26 Ptt Global Chemical Public Co Ltd Novel method to produce acrylic acid with acetaldehyde as the main by-product
CN107849522A (zh) * 2015-07-21 2018-03-27 多伦多大学管理委员会 用于产生1,3‑丁二醇的方法和微生物
EP3390622B1 (en) 2015-12-17 2020-05-13 Evonik Operations GmbH A genetically modified acetogenic cell
CN109415716A (zh) 2016-04-08 2019-03-01 纳幕尔杜邦公司 用于酵母的阿拉伯糖异构酶
WO2018013701A1 (en) 2016-07-12 2018-01-18 Braskem S.A. Formation of alkenes through enzymatic dehydration of alkanols
JP2019523271A (ja) 2016-07-27 2019-08-22 エボニック デグサ ゲーエムベーハーＥｖｏｎｉｋ Ｄｅｇｕｓｓａ ＧｍｂＨ Ｎ−アセチルホモセリン
WO2018085177A1 (en) 2016-11-01 2018-05-11 Biocapital Holdings, Llc Methods for producing carbo sugars and applications thereof
CA3047840A1 (en) 2016-12-21 2018-06-28 Creatus Biosciences Inc. Method and organism expressing metschnikowia xylose transporters for increased xylose uptake
US11345938B2 (en) 2017-02-02 2022-05-31 Cargill, Incorporated Genetically modified cells that produce C6-C10 fatty acid derivatives
US11421235B2 (en) 2017-04-28 2022-08-23 Precigen, Inc. Methods and microorganisms for the fermentation of methane to multi-carbon compounds
CN109722405B (zh) * 2017-10-31 2023-06-23 创享(天津)生物科技发展有限公司 利用葡萄糖生产异丙基吡喃酮的重组大肠杆菌及用途
CN108424865B (zh) * 2018-04-04 2021-06-29 中国农业大学 一株可降解石油并耐受石油的固氮菌pj3-5及其应用
US11149294B2 (en) 2018-05-01 2021-10-19 Biocapital Holdings, Llc DNA constructs and biological devices for producing carbo sugars
US10808265B2 (en) 2018-09-26 2020-10-20 Nantbio, Inc. Microbes and methods for improved conversion of a feedstock
JP6894650B2 (ja) * 2018-10-30 2021-06-30 ＧｒｅｅｎＥａｒｔｈＩｎｓｔｉｔｕｔｅ株式会社 有機化合物の製造方法およびコリネ型細菌
CN111117979B (zh) * 2020-01-14 2020-08-21 中国科学院苏州生物医学工程技术研究所 转氨酶突变体、酶制剂、重组载体、重组细胞及其制备方法和应用
WO2021178805A1 (en) 2020-03-06 2021-09-10 Gevo, Inc. Novel nkr variants for increased production of isobutanol
KR102275630B1 (ko) * 2020-04-08 2021-07-12 한국과학기술원 아미노산의 효소적 전환을 통한 일차 아민의 제조방법
CN111607529B (zh) * 2020-05-15 2021-09-28 江南大学 一株酿酒酵母及其在制备发酵食品中的应用
WO2021253115A1 (en) 2020-06-15 2021-12-23 Melio Peptide Systems Inc. Microorganisms and methods for reducing bacterial contamination
FR3115988A1 (fr) 2020-11-06 2022-05-13 Global Bioenergies Composition de maquillage à base d’isododécane biosourcé et son procédé de préparation
EP4283147A1 (en) 2022-05-24 2023-11-29 Roller Bearing Company of America, Inc. Wear resistant bearing system
WO2025029670A1 (en) * 2023-07-28 2025-02-06 Bp Corporation North America Inc. Production of 2-keto-3-deoxygluconate (kdg) from sucrose
WO2025101633A1 (en) * 2023-11-07 2025-05-15 Bp Corporation North America Inc. Fungal expression systems for low oxygen conditions
FR3157389A1 (fr) 2023-12-22 2025-06-27 Axens Procédé de production de bioalkylat ou d’essence biosourcée
WO2025226576A1 (en) 2024-04-25 2025-10-30 ExxonMobil Technology and Engineering Company Processes for producing isobutylene and isobutylene-based polymers

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4424275A (en) * 1979-09-17 1984-01-03 Sidney Levy Continuous process for producing N-butanol employing anaerobic fermentation
US4568643A (en) * 1981-08-03 1986-02-04 Sidney Levy Continuous process for producing n-butanol employing anaerobic fermentation
US4520104A (en) 1982-11-18 1985-05-28 Cpc International Inc. Production of butanol by a continuous fermentation process
JPS61209594A (ja) 1985-03-14 1986-09-17 Res Assoc Petroleum Alternat Dev<Rapad> アルコ−ルの製造方法
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
JPS6317695A (ja) 1986-07-09 1988-01-25 Idemitsu Kosan Co Ltd アルコ−ル類の製造法
JPS63102687A (ja) 1986-10-20 1988-05-07 Res Assoc Petroleum Alternat Dev<Rapad> ブタノ−ルの製造方法
AT388174B (de) 1987-03-10 1989-05-10 Vogelbusch Gmbh Verfahren zur vergaerung von kohlenhydrathaeltigen medien mit hilfe von bakterien
JPS63254986A (ja) 1987-04-10 1988-10-21 Res Assoc Petroleum Alternat Dev<Rapad> アルコ−ルの製造法
JPH084515B2 (ja) 1987-11-09 1996-01-24 出光興産株式会社 有機化合物の製造方法
US5000000A (en) 1988-08-31 1991-03-19 University Of Florida Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes
US5530189A (en) 1990-03-02 1996-06-25 Amoco Corporation Lycopene biosynthesis in genetically engineered hosts
US5192673A (en) 1990-04-30 1993-03-09 Michigan Biotechnology Institute Mutant strain of C. acetobutylicum and process for making butanol
US5210296A (en) * 1990-11-19 1993-05-11 E. I. Du Pont De Nemours And Company Recovery of lactate esters and lactic acid from fermentation broth
US5210032A (en) * 1992-01-21 1993-05-11 Trustees Of The Boston University Degeneration-resistant solventogenic clostridia
EP0644938A1 (en) 1992-05-29 1995-03-29 E.I. Du Pont De Nemours And Company PRODUCTION OF STREPTAVIDIN FROM $i(BACILLUS SUBTILIS)
US5686276A (en) * 1995-05-12 1997-11-11 E. I. Du Pont De Nemours And Company Bioconversion of a fermentable carbon source to 1,3-propanediol by a single microorganism
JP4327909B2 (ja) * 1996-11-13 2009-09-09 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 組み換え生物による１，３―プロパンジオールの生産方法
IL132883A0 (en) 1997-05-14 2001-03-19 Univ Illinois A method of producing butanol using a mutant strain of clostridium beijerinckii
JP4570702B2 (ja) 1998-07-24 2010-10-27 キリンホールディングス株式会社 香味成分含有量の割合が改変された酒類の製造法
US6787334B1 (en) * 1998-10-09 2004-09-07 Degussa Ag Process for the preparation of pantothenic acid by amplification of nucleotide sequences which code for the ketopantoate reductase
DE19855312A1 (de) * 1998-12-01 2000-06-08 Degussa Verfahren zur fermentativen Herstellung von D-Pantothensäure unter Verwendung coryneformer Bakterien
DE19907567B4 (de) 1999-02-22 2007-08-09 Forschungszentrum Jülich GmbH Verfahren zur mikrobiellen Herstellung von L-Valin
BRPI0013315B8 (pt) 1999-08-18 2018-02-27 Du Pont fragmento de ácido nucleico isolado, polipeptídeo, gene quimérico, microorganismo, microorganismo recombinante , e. coli recombinante, linhagem klp23 de e. coli recombinante, linhagem rj8 de e. coli recombinante, vetor pdt29, vetor pkp32 e processos de bioprodução de 1,3-propanodiol
EP2163629B1 (en) * 1999-09-21 2017-03-08 Basf Se Methods and microorganisms for production of panto-compounds
EP1149918A1 (de) * 2000-04-27 2001-10-31 Creavis Gesellschaft für Technologie und Innovation mbH Verfahren zur Oxidation von Kohlenwasserstoffen unter Verwendung von Mikroorganismen
US6586229B1 (en) 2000-06-01 2003-07-01 North Carolina State University Method for the production of ρ-Hydroxybenzoate in species of pseudomonas and agrobacterium
CN1330133A (zh) * 2000-06-23 2002-01-09 中滨稔 替代汽油的一种燃料
US6660507B2 (en) * 2000-09-01 2003-12-09 E. I. Du Pont De Nemours And Company Genes involved in isoprenoid compound production
RU2215782C2 (ru) * 2001-02-26 2003-11-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ, ШТАММ Escherichia coli - ПРОДУЦЕНТ L-АМИНОКИСЛОТЫ (ВАРИАНТЫ)
US20030203454A1 (en) * 2002-02-08 2003-10-30 Chotani Gopal K. Methods for producing end-products from carbon substrates
EP2374879A3 (en) 2002-04-22 2012-01-11 E. I. du Pont de Nemours and Company Promoter and plasmid system for genetic engineering
CA2491145A1 (en) * 2002-07-03 2004-01-15 Basf Aktiengesellschaft Microorganisms and processes for enhanced production of pantothenate
WO2004033646A2 (en) 2002-10-04 2004-04-22 E.I. Du Pont De Nemours And Company Process for the biological production of 1,3-propanediol with high yield
US9303225B2 (en) 2005-10-26 2016-04-05 Butamax Advanced Biofuels Llc Method for the production of isobutanol by recombinant yeast
MX359740B (es) * 2005-10-26 2018-10-09 Du Pont Produccion fermentativa de alcoholes de cuatro atomos de carbono.
US8273558B2 (en) * 2005-10-26 2012-09-25 Butamax(Tm) Advanced Biofuels Llc Fermentive production of four carbon alcohols
KR100971793B1 (ko) 2006-12-15 2010-07-21 바이오퓨얼켐 주식회사 Ｂｕｔｙｒｙｌ－ＣｏＡ를 중간체로 하여 부탄올을 생합성하는 능력을 가지는 박테리아를 이용하여 부탄올을 제조하는 방법
PL389665A1 (pl) * 2007-02-09 2010-07-05 The Regents of the University of CaliforniaThe Regents of the University of California Wytwarzanie biopaliwa przez rekombinowane mikroorganizmy
WO2009086423A2 (en) * 2007-12-23 2009-07-09 Gevo, Inc. Yeast organism producing isobutanol at a high yield
DE102008010121B4 (de) * 2008-02-20 2013-11-21 Butalco Gmbh Fermentative Produktion von Isobutanol mit Hefe
BRPI0909989A2 (pt) * 2008-06-05 2021-06-22 Butamax Advanced Biofuels Llc célula de levedura recombinante e método para a produção de um produto
FI123498B (fi) * 2008-07-01 2013-05-31 Upm Kymmene Oyj Menetelmä oksapuu-uutteen fraktioimiseksi ja neste-nesteuuton käyttö oksapuu-uutteen puhdistamiseksi
WO2010037119A1 (en) * 2008-09-29 2010-04-01 Butamax™ Advanced Biofuels LLC Enhanced iron-sulfur cluster formation for increased dihydroxy-acid dehydratase activity in lactic acid bacteria
CA2737112A1 (en) * 2008-10-27 2010-06-03 Butamax Advanced Biofuels Llc Carbon pathway optimized production hosts for the production of isobutanol
US8828694B2 (en) * 2008-11-13 2014-09-09 Butamax Advanced Biofuels Llc Production of isobutanol in yeast mitochondria
WO2010068821A1 (en) * 2008-12-10 2010-06-17 Synthetic Genomics, Inc. Production of branched-chain alcohols by photosynthetic microoraganisms
US8178832B1 (en) * 2011-05-31 2012-05-15 Wong Jacob Y Re-calibration methodology for NDIR gas sensors

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