JP5270167B2 - （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形 - Google Patents

（ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形 Download PDF

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JP5270167B2
JP5270167B2 JP2007547060A JP2007547060A JP5270167B2 JP 5270167 B2 JP5270167 B2 JP 5270167B2 JP 2007547060 A JP2007547060 A JP 2007547060A JP 2007547060 A JP2007547060 A JP 2007547060A JP 5270167 B2 JP5270167 B2 JP 5270167B2
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hemihydrate
disorder
composition
compound according
tetrahydro
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JP2008524262A (ja
JP2008524262A5 (enExample
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ラジェッシュ クマール アガーワル，
ウィリアム エル． ザ サード ベッツ，
ジェームス エー． ヘンシルウッド，
ユアン−ホン キヤン，
ノア ポスト，
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アリーナ ファーマシューティカルズ， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
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    • A61P25/36—Opioid-abuse
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    • A—HUMAN NECESSITIES
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    • A61P3/04—Anorexiants; Antiobesity agents
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
JP2007547060A 2004-12-21 2005-12-20 （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形 Expired - Fee Related JP5270167B2 (ja)

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Application Number Priority Date Filing Date Title
US63822104P 2004-12-21 2004-12-21
US60/638,221 2004-12-21
PCT/US2005/046983 WO2006069363A2 (en) 2004-12-21 2005-12-20 Crystalline forms of (r)-8-chloro-1-methyl- 2,3,4,5-tetrahydro-1h-3-benzazepine hydrochloride

Related Child Applications (1)

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JP2012114460A Division JP5781008B2 (ja) 2004-12-21 2012-05-18 （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形

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JP2008524262A JP2008524262A (ja) 2008-07-10
JP2008524262A5 JP2008524262A5 (enExample) 2009-02-05
JP5270167B2 true JP5270167B2 (ja) 2013-08-21

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JP2007547060A Expired - Fee Related JP5270167B2 (ja) 2004-12-21 2005-12-20 （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形
JP2012114460A Expired - Fee Related JP5781008B2 (ja) 2004-12-21 2012-05-18 （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形
JP2014113743A Pending JP2014156490A (ja) 2004-12-21 2014-06-02 （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形

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JP2012114460A Expired - Fee Related JP5781008B2 (ja) 2004-12-21 2012-05-18 （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形
JP2014113743A Pending JP2014156490A (ja) 2004-12-21 2014-06-02 （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形

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US (4) US8168624B2 (enExample)
EP (3) EP2149562A1 (enExample)
JP (3) JP5270167B2 (enExample)
KR (1) KR101281919B1 (enExample)
CN (2) CN101084193B (enExample)
AT (1) ATE442359T1 (enExample)
AU (1) AU2005318959B2 (enExample)
BR (1) BRPI0519726B8 (enExample)
CA (1) CA2589988C (enExample)
CU (1) CU20070138A7 (enExample)
CY (1) CY1109599T1 (enExample)
DE (1) DE602005016603D1 (enExample)
DK (1) DK1838677T3 (enExample)
EA (2) EA017894B1 (enExample)
ES (1) ES2332009T3 (enExample)
HR (1) HRP20090640T1 (enExample)
IL (1) IL183844A (enExample)
MA (1) MA29147B1 (enExample)
ME (1) ME01090B (enExample)
NI (1) NI200700160A (enExample)
NZ (2) NZ589756A (enExample)
PL (1) PL1838677T3 (enExample)
PT (1) PT1838677E (enExample)
RS (1) RS50996B (enExample)
SI (1) SI1838677T1 (enExample)
TN (1) TNSN07235A1 (enExample)
WO (1) WO2006069363A2 (enExample)
ZA (1) ZA200705125B (enExample)

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