JP5122445B2 - 抗認知症薬物の経皮吸収製剤 - Google Patents

抗認知症薬物の経皮吸収製剤 Download PDF

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JP5122445B2
JP5122445B2 JP2008514366A JP2008514366A JP5122445B2 JP 5122445 B2 JP5122445 B2 JP 5122445B2 JP 2008514366 A JP2008514366 A JP 2008514366A JP 2008514366 A JP2008514366 A JP 2008514366A JP 5122445 B2 JP5122445 B2 JP 5122445B2
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drug
meth
acrylate
ester
containing layer
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JPWO2007129427A1 (ja
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東 健 伊
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Teikoku Seiyaku Co Ltd
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Teikoku Seiyaku Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2008514366A 2006-05-08 2006-12-25 抗認知症薬物の経皮吸収製剤 Active JP5122445B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79829606P 2006-05-08 2006-05-08
US60/798,296 2006-05-08
PCT/JP2006/325813 WO2007129427A1 (ja) 2006-05-08 2006-12-25 抗認知症薬物の経皮吸収製剤

Publications (2)

Publication Number Publication Date
JPWO2007129427A1 JPWO2007129427A1 (ja) 2009-09-17
JP5122445B2 true JP5122445B2 (ja) 2013-01-16

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US (2) US7858114B2 (enExample)
EP (1) EP2016939B1 (enExample)
JP (1) JP5122445B2 (enExample)
KR (1) KR20090009951A (enExample)
CN (1) CN101460156B (enExample)
AU (1) AU2006343077B2 (enExample)
BR (1) BRPI0621655A2 (enExample)
CA (1) CA2651596C (enExample)
ES (1) ES2466647T3 (enExample)
IL (1) IL195174A0 (enExample)
IN (1) IN266817B (enExample)
MY (1) MY149152A (enExample)
NO (1) NO20084614L (enExample)
NZ (1) NZ572809A (enExample)
RU (1) RU2428179C2 (enExample)
WO (1) WO2007129427A1 (enExample)

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CA2719605C (en) * 2008-03-25 2016-07-12 Teikoku Seiyaku Co., Ltd. Transdermally absorbable preparation
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EP2279739B2 (en) * 2008-05-30 2018-02-28 Nitto Denko Corporation Donepezil-containing patch preparation and packaging thereof
BRPI0912099A2 (pt) * 2008-05-30 2015-10-06 Eisai R&D Man Co Ltd preparação percutaneamente absorvível
US20100080842A1 (en) * 2008-09-30 2010-04-01 Jianye Wen Transdermal extended-delivery donepezil compositions and methods for using the same
US8858983B2 (en) 2009-04-30 2014-10-14 Medtronic, Inc. Antioxidants and antimicrobial accessories including antioxidants
KR101325104B1 (ko) * 2009-09-16 2013-11-07 주식회사 삼양바이오팜 경피 투여 제형 및 그 제조 방법
KR20120101704A (ko) * 2009-12-16 2012-09-14 고토 다케시 항인지증 약물의 경피흡수제제
JP2012236773A (ja) * 2009-12-16 2012-12-06 Goto Takeshi 抗認知症薬物の経皮吸収製剤
TW201143817A (en) * 2009-12-16 2011-12-16 Goto Takeshi Transdermally absorbed preparation of anti-dementia drug
US10076502B2 (en) 2009-12-22 2018-09-18 Luye Pharma Ag Transdermal therapeutic system for administering rivastigmine or derivatives thereof
US8962014B2 (en) * 2009-12-22 2015-02-24 Acino Ag Transdermal therapeutic system for administering rivastigmine or derivatives thereof
US20100178307A1 (en) * 2010-01-13 2010-07-15 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
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RS54173B1 (sr) 2010-12-14 2015-12-31 Acino Ag Transdermalni terapijski sistem za davanje aktivne supstance
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KR101054317B1 (ko) 2011-01-28 2011-08-08 신신제약 주식회사 리바스티그민을 함유하는 경피흡수제제
KR101317158B1 (ko) 2011-02-18 2013-10-15 조선대학교산학협력단 갈란타민 또는 그의 염을 함유하는 경피흡수제제
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KR101395557B1 (ko) * 2011-08-25 2014-05-16 아이큐어 주식회사 경피 흡수 제제 및 그 제조방법
KR101239150B1 (ko) 2012-02-28 2013-03-06 에스케이케미칼주식회사 도네페질-함유 경피흡수제제 및 그의 제조방법
KR101964295B1 (ko) * 2012-09-05 2019-04-01 주식회사 한독 피부 자극이 감소된 메만틴 경피전달 시스템
KR102171152B1 (ko) * 2012-12-13 2020-10-29 하. 룬드벡 아크티에셀스카브 보르티옥세틴 및 도네페질을 포함하는 조성물
JP6151935B2 (ja) * 2013-03-11 2017-06-21 日東電工株式会社 経皮吸収促進用組成物および貼付製剤
CN106456562B (zh) 2014-02-20 2020-01-31 安能泰制药有限公司 含有多奈哌齐的透皮药物递送系统
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JP6148416B2 (ja) 2015-06-29 2017-06-14 積水化学工業株式会社 コアシェル構造体及び外用剤
US10966936B2 (en) 2015-12-30 2021-04-06 Corium, Inc. Systems comprising a composite backing and methods for long term transdermal administration
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CN108096690B (zh) * 2017-04-07 2019-08-20 杭州多泰科技有限公司 一种诱导循环肿瘤细胞转移的可移植支架的制备方法
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CN111132669A (zh) * 2017-07-26 2020-05-08 考里安公司 具有带溶剂填充孔的微孔膜的透皮递送系统
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JPH04117323A (ja) * 1990-09-04 1992-04-17 Sekisui Chem Co Ltd 経皮吸収貼付剤
JPH05500511A (ja) * 1989-09-14 1993-02-04 シグナス，インコーポレイテッド 送達開始を遅延させた経皮送達装置
JPH06199659A (ja) * 1992-10-28 1994-07-19 Hisamitsu Pharmaceut Co Inc 経皮治療用装置
JPH06510043A (ja) * 1991-08-23 1994-11-10 シグナス，インコーポレイテッド 薬効遅延を達成するために膜で保護された微細孔膜を用いる経皮ドラッグデリバリーデバイス
JPH10182439A (ja) * 1996-12-20 1998-07-07 Roehm Gmbh 皮膚もしくは経皮の治療系のための付着−及び接合剤
JPH11501527A (ja) * 1994-09-29 1999-02-09 アルザ・コーポレーション 離層の少ない改良された経皮デバイス
JPH11315016A (ja) * 1998-03-03 1999-11-16 Eisai Co Ltd 抗痴呆薬を含有した経皮適用製剤又は坐剤
WO2002038139A1 (en) * 2000-11-07 2002-05-16 Hisamitsu Pharmaceutical Co., Inc. Pharmaceutical preparation of percutaneous absorption type
JP2003505411A (ja) * 1999-07-22 2003-02-12 エルテーエス ローマン テラピー−ジステーメ アーゲー カルシウムアンタゴニストを投与するための経皮治療系
WO2003032960A1 (en) * 2001-10-17 2003-04-24 Hisamitsu Pharmaceutical Co., Inc. Percutaneous absorption preparations
WO2003092677A1 (de) * 2002-05-06 2003-11-13 Schwarz Pharma Ag Transepikutane darreichungsform zur behandlung des restless leg syndroms
JP2004502725A (ja) * 2000-07-12 2004-01-29 ヘクサル・アクチェンゲゼルシャフト 高分散シリカを用いた経皮治療システム
JP2004509916A (ja) * 2000-09-26 2004-04-02 ピエール、ファーブル、メディカマン オキサンに基づく薬剤
JP2004514738A (ja) * 2000-12-06 2004-05-20 エルテーエス　ローマン　テラピー−ジステーメ　アーゲー 活性物質としてオキシブチニンで構成される経皮治療システム
JP2005194230A (ja) * 2004-01-07 2005-07-21 Hisamitsu Pharmaceut Co Inc 異型断面繊維を使用した支持体を有するテーピング型貼付剤
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JPH05500511A (ja) * 1989-09-14 1993-02-04 シグナス，インコーポレイテッド 送達開始を遅延させた経皮送達装置
JPH04117323A (ja) * 1990-09-04 1992-04-17 Sekisui Chem Co Ltd 経皮吸収貼付剤
JPH06510043A (ja) * 1991-08-23 1994-11-10 シグナス，インコーポレイテッド 薬効遅延を達成するために膜で保護された微細孔膜を用いる経皮ドラッグデリバリーデバイス
JPH06199659A (ja) * 1992-10-28 1994-07-19 Hisamitsu Pharmaceut Co Inc 経皮治療用装置
JPH11501527A (ja) * 1994-09-29 1999-02-09 アルザ・コーポレーション 離層の少ない改良された経皮デバイス
JPH10182439A (ja) * 1996-12-20 1998-07-07 Roehm Gmbh 皮膚もしくは経皮の治療系のための付着−及び接合剤
JPH11315016A (ja) * 1998-03-03 1999-11-16 Eisai Co Ltd 抗痴呆薬を含有した経皮適用製剤又は坐剤
JP2003505411A (ja) * 1999-07-22 2003-02-12 エルテーエス ローマン テラピー−ジステーメ アーゲー カルシウムアンタゴニストを投与するための経皮治療系
JP2004502725A (ja) * 2000-07-12 2004-01-29 ヘクサル・アクチェンゲゼルシャフト 高分散シリカを用いた経皮治療システム
JP2004509916A (ja) * 2000-09-26 2004-04-02 ピエール、ファーブル、メディカマン オキサンに基づく薬剤
WO2002038139A1 (en) * 2000-11-07 2002-05-16 Hisamitsu Pharmaceutical Co., Inc. Pharmaceutical preparation of percutaneous absorption type
JP2004514738A (ja) * 2000-12-06 2004-05-20 エルテーエス　ローマン　テラピー−ジステーメ　アーゲー 活性物質としてオキシブチニンで構成される経皮治療システム
WO2003032960A1 (en) * 2001-10-17 2003-04-24 Hisamitsu Pharmaceutical Co., Inc. Percutaneous absorption preparations
WO2003092677A1 (de) * 2002-05-06 2003-11-13 Schwarz Pharma Ag Transepikutane darreichungsform zur behandlung des restless leg syndroms
JP2005194230A (ja) * 2004-01-07 2005-07-21 Hisamitsu Pharmaceut Co Inc 異型断面繊維を使用した支持体を有するテーピング型貼付剤
WO2005115355A1 (ja) * 2004-05-28 2005-12-08 Hisamitsu Pharmaceutical Co., Inc. 貼付製剤

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EP2016939A1 (en) 2009-01-21
CN101460156A (zh) 2009-06-17
BRPI0621655A2 (pt) 2011-12-20
ES2466647T3 (es) 2014-06-10
AU2006343077A1 (en) 2007-11-15
US7858114B2 (en) 2010-12-28
CA2651596C (en) 2014-03-25
IN266817B (enExample) 2015-06-03
AU2006343077B2 (en) 2012-11-08
MY149152A (en) 2013-07-15
RU2428179C2 (ru) 2011-09-10
KR20090009951A (ko) 2009-01-23
HK1130175A1 (en) 2009-12-24
NO20084614L (no) 2009-02-06
IL195174A0 (en) 2009-08-03
US20070259028A1 (en) 2007-11-08
CN101460156B (zh) 2011-06-08
NZ572809A (en) 2011-02-25
EP2016939B1 (en) 2014-03-19
US20110059141A1 (en) 2011-03-10
RU2008148131A (ru) 2010-06-20
EP2016939A4 (en) 2013-01-09
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