JP5082053B2 - マイクロ針またはマイクロインプラントの製造方法 - Google Patents

マイクロ針またはマイクロインプラントの製造方法 Download PDF

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Publication number
JP5082053B2
JP5082053B2 JP2007526569A JP2007526569A JP5082053B2 JP 5082053 B2 JP5082053 B2 JP 5082053B2 JP 2007526569 A JP2007526569 A JP 2007526569A JP 2007526569 A JP2007526569 A JP 2007526569A JP 5082053 B2 JP5082053 B2 JP 5082053B2
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Prior art keywords
solid
needle
droplet
substance
droplets
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2007526569A
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English (en)
Japanese (ja)
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JP2008509771A5 (OSRAM
JP2008509771A (ja
Inventor
キルビー、アンドリュー、ジェイムズ
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イノチュア アイ・ピー リミテッド
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Filing date
Publication date
Priority claimed from GBGB0418246.5A external-priority patent/GB0418246D0/en
Priority claimed from GBGB0427762.0A external-priority patent/GB0427762D0/en
Application filed by イノチュア アイ・ピー リミテッド filed Critical イノチュア アイ・ピー リミテッド
Publication of JP2008509771A publication Critical patent/JP2008509771A/ja
Publication of JP2008509771A5 publication Critical patent/JP2008509771A5/ja
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Publication of JP5082053B2 publication Critical patent/JP5082053B2/ja
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B81MICROSTRUCTURAL TECHNOLOGY
    • B81CPROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C1/00Manufacture or treatment of devices or systems in or on a substrate
    • B81C1/00015Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
    • B81C1/00023Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems without movable or flexible elements
    • B81C1/00111Tips, pillars, i.e. raised structures
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C37/00Component parts, details, accessories or auxiliary operations, not covered by group B29C33/00 or B29C35/00
    • B29C37/0053Moulding articles characterised by the shape of the surface, e.g. ribs, high polish
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10Processes of additive manufacturing
    • B29C64/106Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
    • B29C64/124Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified
    • B29C64/129Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified characterised by the energy source therefor, e.g. by global irradiation combined with a mask
    • B29C64/135Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using layers of liquid which are selectively solidified characterised by the energy source therefor, e.g. by global irradiation combined with a mask the energy source being concentrated, e.g. scanning lasers or focused light sources
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053Methods for producing microneedles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0805Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
    • B29C2035/0827Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation using UV radiation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29LINDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00Other particular articles
    • B29L2031/759Needles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00Products made by additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B81MICROSTRUCTURAL TECHNOLOGY
    • B81BMICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00Specific applications of microelectromechanical systems
    • B81B2201/05Microfluidics
    • B81B2201/055Microneedles

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Optics & Photonics (AREA)
  • Materials Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
JP2007526569A 2004-08-16 2005-08-16 マイクロ針またはマイクロインプラントの製造方法 Expired - Fee Related JP5082053B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB0418246.5A GB0418246D0 (en) 2004-08-16 2004-08-16 Method for producing microneedles, microimplants and arrays thereof
GB0418246.5 2004-08-16
GB0427762.0 2004-12-17
GBGB0427762.0A GB0427762D0 (en) 2004-12-17 2004-12-17 Device and method for transport across barrier
PCT/GB2005/003224 WO2006018642A1 (en) 2004-08-16 2005-08-16 Method of producing a microneedle or microimplant

Publications (3)

Publication Number Publication Date
JP2008509771A JP2008509771A (ja) 2008-04-03
JP2008509771A5 JP2008509771A5 (OSRAM) 2008-08-28
JP5082053B2 true JP5082053B2 (ja) 2012-11-28

Family

ID=35447243

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007526569A Expired - Fee Related JP5082053B2 (ja) 2004-08-16 2005-08-16 マイクロ針またはマイクロインプラントの製造方法

Country Status (7)

Country Link
US (1) US8192787B2 (OSRAM)
EP (3) EP2272430A1 (OSRAM)
JP (1) JP5082053B2 (OSRAM)
AT (1) ATE490037T1 (OSRAM)
DE (1) DE602005025138D1 (OSRAM)
ES (1) ES2463818T3 (OSRAM)
WO (1) WO2006018642A1 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170131283A (ko) * 2016-05-20 2017-11-29 주식회사 라파스 마이크로니들 제조방법

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7699819B2 (en) 2006-02-21 2010-04-20 The Hong Kong University Of Science And Technology Molecular sieve and zeolite microneedles and preparation thereof
CN100460028C (zh) * 2006-12-08 2009-02-11 中国科学院上海微系统与信息技术研究所 一种用于药物传输的微针阵列及其制作方法
WO2008093679A1 (ja) * 2007-01-29 2008-08-07 Medrx Co., Ltd. 温度感受性物質製のマイクロニードルの製造方法
JP4959363B2 (ja) * 2007-02-14 2012-06-20 凸版印刷株式会社 針状体の製造方法
JP4978243B2 (ja) * 2007-03-06 2012-07-18 凸版印刷株式会社 針状体および針状体製造方法
US8366677B2 (en) * 2007-08-06 2013-02-05 Transderm, Inc. Microneedle arrays formed from polymer films
KR20100037389A (ko) * 2008-10-01 2010-04-09 연세대학교 산학협력단 다중 약물방출조절이 가능한 솔리드 마이크로구조체 및 이의 제조방법
KR101136738B1 (ko) * 2008-10-02 2012-04-19 주식회사 라파스 송풍에 의한 솔리드 마이크로구조체의 제조방법 및 이로부터 제조된 솔리드 마이크로구조체
WO2010137319A1 (ja) * 2009-05-27 2010-12-02 株式会社メドレックス 剣山型マイクロニードルの製造方法およびマイクロニードル
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
KR101254240B1 (ko) * 2010-12-17 2013-04-12 주식회사 라파스 마이크로구조체 제조방법
KR101180032B1 (ko) * 2010-07-12 2012-09-05 인싸이토(주) 외형 조절이 가능한 중공형 마이크로니들의 제조방법
HK1209658A1 (en) 2012-05-01 2016-04-08 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Tip-loaded microneedle arrays for transdermal insertion
WO2014153228A1 (en) * 2013-03-14 2014-09-25 Perryman Laura Tyler Miniature implantable device and methods
US10245436B2 (en) 2012-07-17 2019-04-02 Stimwave Technologies Incorporated Miniature implantable device and methods
WO2014129816A1 (ko) * 2013-02-22 2014-08-28 연세대학교 산학협력단 음압을 이용한 마이크로구조체의 제조방법 및 그로부터 제조된 마이크로구조체
US20160279401A1 (en) 2015-03-27 2016-09-29 Allergan, Inc. Dissolvable microneedles for skin treatment
WO2016149673A1 (en) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bioactive components conjugated to substrates of microneedle arrays
JP2016195651A (ja) * 2015-04-02 2016-11-24 日本写真印刷株式会社 マイクロニードルシート
US11684763B2 (en) 2015-10-16 2023-06-27 University of Pittsburgh—of the Commonwealth System of Higher Education Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices
US11744889B2 (en) 2016-01-05 2023-09-05 University of Pittsburgh—of the Commonwealth System of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
JP6708747B2 (ja) 2016-02-15 2020-06-10 シャンハイ ジャオ トン ユニバーシティ マイクロ針パッチの高速印刷方法
KR101816922B1 (ko) * 2016-05-20 2018-01-09 주식회사 라파스 마이크로니들 제조방법
JP2020507422A (ja) 2017-02-17 2020-03-12 アラーガン、インコーポレイテッドAllergan,Incorporated 活性成分を含むマイクロニードルアレイ
CN109420245A (zh) * 2017-08-30 2019-03-05 优微(珠海)生物科技有限公司 可溶性微针的制造方法
AU2020275934B2 (en) 2019-05-16 2025-09-25 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Microneedle arrays with undercut features for cutaneous and non-cutaneous drug delivery
GB2586474A (en) 2019-08-20 2021-02-24 Innoture Ip Ltd Method of manufacturing microstructures
GB2586475A (en) * 2019-08-20 2021-02-24 Innoture Ip Ltd Methods
CN112618922A (zh) * 2020-12-30 2021-04-09 上海心至医疗科技有限公司 一种药物球囊的制备方法、制备得到的药物球囊及其应用

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
JPS5428369A (en) * 1977-08-03 1979-03-02 Yamakawa Tsuneko Method of forming needleelike projection of thermoplastic resin on sheet
JPS6216132A (ja) * 1985-07-12 1987-01-24 Shimano & Co Ltd 滑り止め突起を備えた釣竿の製造法
US5309909A (en) 1992-05-22 1994-05-10 Physio-Control Corporation Combined skin preparation and monitoring electrode
US7422574B2 (en) 1995-05-19 2008-09-09 Applied Tissue Technologies, Llc Microseeding device for gene delivery by microneedle injection
WO1999064580A1 (en) 1998-06-10 1999-12-16 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
US6689103B1 (en) 1999-05-07 2004-02-10 Scimed Life System, Inc. Injection array apparatus and method
EP1187653B1 (en) 1999-06-04 2010-03-31 Georgia Tech Research Corporation Devices for enhanced microneedle penetration of biological barriers
US6743211B1 (en) 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6312612B1 (en) * 1999-06-09 2001-11-06 The Procter & Gamble Company Apparatus and method for manufacturing an intracutaneous microneedle array
US6379324B1 (en) 1999-06-09 2002-04-30 The Procter & Gamble Company Intracutaneous microneedle array apparatus
US6623457B1 (en) 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
US8465468B1 (en) 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
US6511463B1 (en) 1999-11-18 2003-01-28 Jds Uniphase Corporation Methods of fabricating microneedle arrays using sacrificial molds
AU2736501A (en) 1999-12-30 2001-07-16 Redeon, Inc. Stacked microneedle systems
US6558361B1 (en) 2000-03-09 2003-05-06 Nanopass Ltd. Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems
EP1276426A4 (en) 2000-03-09 2008-03-19 Nanopass Ltd SYSTEMS AND METHODS FOR TRANSPORTING FLUIDS THROUGH A BIOLOGICAL BARRIER AND TECHNIQUES FOR PRODUCING SUCH SYSTEMS
AU2001265056A1 (en) 2000-05-26 2001-12-11 The Procter And Gamble Company Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup
WO2001093930A1 (en) 2000-06-02 2001-12-13 The University Of Utah Research Foundation Active needle devices with integrated functionality
US6440096B1 (en) 2000-07-14 2002-08-27 Becton, Dickinson And Co. Microdevice and method of manufacturing a microdevice
WO2002015960A2 (en) 2000-08-21 2002-02-28 The Cleveland Clinic Foundation Microneedle array module and method of fabricating the same
US6533949B1 (en) 2000-08-28 2003-03-18 Nanopass Ltd. Microneedle structure and production method therefor
WO2002028471A1 (de) 2000-10-05 2002-04-11 Thomas Marsoner Medizinische injektionseinrichtung
AU2002237703A1 (en) 2000-11-09 2002-06-18 Biovalve Technologies, Inc. Microneedle adapter
EP1345646A2 (en) 2000-12-14 2003-09-24 Georgia Tech Research Corporation Microneedle devices and production thereof
GB0030929D0 (en) 2000-12-19 2001-01-31 Inverness Medical Ltd Analyte measurement
AU2002231207A1 (en) 2000-12-21 2002-07-01 Biovalve Technologies, Inc. Microneedle array systems
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
US6591124B2 (en) 2001-05-11 2003-07-08 The Procter & Gamble Company Portable interstitial fluid monitoring system
US7127284B2 (en) 2001-06-11 2006-10-24 Mercator Medsystems, Inc. Electroporation microneedle and methods for its use
US6767341B2 (en) 2001-06-13 2004-07-27 Abbott Laboratories Microneedles for minimally invasive drug delivery
US6881203B2 (en) 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
US8361037B2 (en) 2001-09-19 2013-01-29 Valeritas, Inc. Microneedles, microneedle arrays, and systems and methods relating to same
WO2003024508A2 (en) 2001-09-21 2003-03-27 Biovalve Technologies, Inc. Gas pressure actuated microneedle arrays, and systems and methods relating to same
AU2002343457A1 (en) 2001-09-28 2003-04-07 Biovalve Technologies, Inc. Switchable microneedle arrays and systems and methods relating to same
EP1469903A2 (en) 2001-09-28 2004-10-27 BioValve Technologies, Inc. Microneedle with membrane
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US6908453B2 (en) 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US20030171734A1 (en) 2002-01-22 2003-09-11 Endobionics, Inc. Methods and kits for delivering pharmaceutical agents into the coronary vascular adventitia
GB0201736D0 (en) 2002-01-25 2002-03-13 Glaxo Group Ltd DNA dosage forms
US7004928B2 (en) 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
JP4090018B2 (ja) * 2002-02-18 2008-05-28 For Head株式会社 機能性マイクロパイル及びその製造方法
US7115108B2 (en) 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US6780171B2 (en) 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
GB0216333D0 (en) 2002-07-13 2002-08-21 Univ Cranfield Substance - selective polymer membranes
WO2004009172A1 (en) 2002-07-19 2004-01-29 3M Innovative Properties Company Microneedle devices and microneedle delivery apparatus
ATE510494T1 (de) 2002-09-06 2011-06-15 Massachusetts Inst Technology Messung der eigenschaften eines anatomischen körpers
WO2004033021A1 (en) 2002-10-07 2004-04-22 Biovalve Technologies, Inc. Microneedle array patch
IL152271A (en) * 2002-10-13 2006-04-10 Meir Hefetz Structures of micro needles and manufacturing methods
WO2004035105A2 (en) * 2002-10-13 2004-04-29 Nano Pass Technologies Ltd. Polymer microneedles
KR100563330B1 (ko) 2003-01-16 2006-03-22 포스트마이크로 주식회사 Liga공정을 이용한 폴리머 재질의 미세 바늘 어레이제조방법
WO2004064889A2 (en) 2003-01-16 2004-08-05 Becton, Dickinson And Company Intradermal cellular delivery using narrow gauge micro-cannula
EP1632263A4 (en) * 2003-06-10 2008-04-30 Medrx Co Ltd METHOD FOR THE PRODUCTION OF A REFERENCE BASIS FOR TRANSDERMAL MEDICINAL ADMINISTRATION, BASIC BASIS FOR TRANSDERMAL ADMINISTRATIVE ADMINISTRATION AND NEEDLE
US7273474B2 (en) 2003-06-17 2007-09-25 Industrial Technology Research Institute Flexible substrate structure for microneedle arrays and its manufacturing method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170131283A (ko) * 2016-05-20 2017-11-29 주식회사 라파스 마이크로니들 제조방법

Also Published As

Publication number Publication date
ES2463818T3 (es) 2014-05-29
EP2272430A1 (en) 2011-01-12
US8192787B2 (en) 2012-06-05
EP2289646B1 (en) 2014-02-12
EP1786580B1 (en) 2010-12-01
EP2289646A1 (en) 2011-03-02
WO2006018642A1 (en) 2006-02-23
DE602005025138D1 (de) 2011-01-13
US20080299290A1 (en) 2008-12-04
JP2008509771A (ja) 2008-04-03
ATE490037T1 (de) 2010-12-15
EP1786580A1 (en) 2007-05-23

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