EP1276426A4 - Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems - Google Patents
Systems and methods for the transport of fluids through a biological barrier and production techniques for such systemsInfo
- Publication number
- EP1276426A4 EP1276426A4 EP01918390A EP01918390A EP1276426A4 EP 1276426 A4 EP1276426 A4 EP 1276426A4 EP 01918390 A EP01918390 A EP 01918390A EP 01918390 A EP01918390 A EP 01918390A EP 1276426 A4 EP1276426 A4 EP 1276426A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- systems
- fluids
- transport
- methods
- production techniques
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
- B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
- B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
- B81C1/00023—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems without movable or flexible elements
- B81C1/00111—Tips, pillars, i.e. raised structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
- A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/150022—Source of blood for capillary blood or interstitial fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150213—Venting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150221—Valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150229—Pumps for assisting the blood sampling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150274—Manufacture or production processes or steps for blood sampling devices
- A61B5/150282—Manufacture or production processes or steps for blood sampling devices for piercing elements, e.g. blade, lancet, canula, needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
- A61B5/150381—Design of piercing elements
- A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
- A61B5/150396—Specific tip design, e.g. for improved penetration characteristics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
- A61B5/150381—Design of piercing elements
- A61B5/150412—Pointed piercing elements, e.g. needles, lancets for piercing the skin
- A61B5/150427—Specific tip design, e.g. for improved penetration characteristics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
- A61B5/150381—Design of piercing elements
- A61B5/150503—Single-ended needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150847—Communication to or from blood sampling device
- A61B5/150854—Communication to or from blood sampling device long distance, e.g. between patient's home and doctor's office
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150977—Arrays of piercing elements for simultaneous piercing
- A61B5/150984—Microneedles or microblades
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/157—Devices characterised by integrated means for measuring characteristics of blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0053—Methods for producing microneedles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B2201/00—Specific applications of microelectromechanical systems
- B81B2201/05—Microfluidics
- B81B2201/055—Microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Manufacturing & Machinery (AREA)
- Dermatology (AREA)
- Optics & Photonics (AREA)
- Anesthesiology (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US589368 | 1990-09-28 | ||
US589369 | 1990-09-28 | ||
IL13499700 | 2000-03-09 | ||
IL13499700A IL134997A0 (en) | 2000-03-09 | 2000-03-09 | Health care system based on micro device |
US58936800A | 2000-06-08 | 2000-06-08 | |
US09/589,369 US6558361B1 (en) | 2000-03-09 | 2000-06-08 | Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems |
PCT/US2001/007170 WO2001066065A2 (en) | 2000-03-09 | 2001-03-07 | Systems and methods for fluid transport through dermal barriers |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1276426A2 EP1276426A2 (en) | 2003-01-22 |
EP1276426A4 true EP1276426A4 (en) | 2008-03-19 |
Family
ID=27271924
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP01918390A Withdrawn EP1276426A4 (en) | 2000-03-09 | 2001-03-07 | Systems and methods for the transport of fluids through a biological barrier and production techniques for such systems |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1276426A4 (en) |
AU (1) | AU2001245472A1 (en) |
WO (1) | WO2001066065A2 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020095134A1 (en) * | 1999-10-14 | 2002-07-18 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
GB0030929D0 (en) * | 2000-12-19 | 2001-01-31 | Inverness Medical Ltd | Analyte measurement |
US6908453B2 (en) | 2002-01-15 | 2005-06-21 | 3M Innovative Properties Company | Microneedle devices and methods of manufacture |
US7588552B2 (en) | 2002-03-04 | 2009-09-15 | Nano Pass Technologies Ltd. | Devices and methods for transporting fluid across a biological barrier |
US8671544B2 (en) | 2004-03-12 | 2014-03-18 | Agency For Science, Technology And Research | Methods and moulds for use in fabricating side-ported microneedles |
DE602005025138D1 (en) | 2004-08-16 | 2011-01-13 | Fuctional Microstructures Ltd | METHOD FOR PRODUCING A MICRONADEL OR A MICROIMPLANTATE |
CA2641034C (en) * | 2006-01-31 | 2013-04-09 | Francis A. Kralick | Implantable micro-system for treatment of hydrocephalus |
US8206334B2 (en) | 2006-01-31 | 2012-06-26 | Kralick Francis A | Implantable micro-system for treatment of hydrocephalus |
JP2009545368A (en) * | 2006-08-01 | 2009-12-24 | エージェンシー フォー サイエンス,テクノロジー アンド リサーチ | Ultrasonic enhanced micro needle |
EP1967581B1 (en) * | 2007-03-08 | 2016-08-17 | Imec | CMOS compatible method for manufacturing microneedle structures |
EP2338557A1 (en) | 2009-12-23 | 2011-06-29 | Debiotech S.A. | Soluble microneedle |
EP2343550B1 (en) | 2009-12-30 | 2013-11-06 | Imec | Improved microneedle |
WO2019058329A1 (en) * | 2017-09-22 | 2019-03-28 | Sabic Global Technologies B.V. | Methods and systems of producing microneedle arrays |
US11690739B1 (en) | 2020-08-25 | 2023-07-04 | Francis A. Kralick | Implantable device for treatment of hydrocephalus |
US11717660B2 (en) | 2021-07-29 | 2023-08-08 | Nanopass Technologies Ltd. | Silicon microneedle structure and production method |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
FR2535602A1 (en) * | 1982-11-05 | 1984-05-11 | Stallergenes Lab | Scarifying device |
EP0407063A1 (en) * | 1989-07-06 | 1991-01-09 | Connaught Laboratories Limited | Tines structure of clinical applicator |
WO1996017648A1 (en) * | 1994-12-09 | 1996-06-13 | Novartis Ag | Transdermal system |
DE19525607A1 (en) * | 1995-07-14 | 1997-01-16 | Boehringer Ingelheim Kg | Transcorneal drug delivery system |
WO1998000193A1 (en) * | 1996-07-03 | 1998-01-08 | Altea Technologies, Inc. | Multiple mechanical microporation of skin or mucosa |
WO2000009184A1 (en) * | 1998-08-13 | 2000-02-24 | Imprint Pharmaceuticals Limited | Apparatus for delivering a substance having one or more needles driven at high velocity |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0429842B1 (en) * | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
US6090790A (en) * | 1989-12-14 | 2000-07-18 | Eriksson; Elof | Gene delivery by microneedle injection |
US5591139A (en) * | 1994-06-06 | 1997-01-07 | The Regents Of The University Of California | IC-processed microneedles |
US6077251A (en) * | 1997-10-30 | 2000-06-20 | Ting; Windsor | Medicinal agent administration system |
-
2001
- 2001-03-07 WO PCT/US2001/007170 patent/WO2001066065A2/en active Application Filing
- 2001-03-07 AU AU2001245472A patent/AU2001245472A1/en not_active Abandoned
- 2001-03-07 EP EP01918390A patent/EP1276426A4/en not_active Withdrawn
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3964482A (en) * | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
FR2535602A1 (en) * | 1982-11-05 | 1984-05-11 | Stallergenes Lab | Scarifying device |
EP0407063A1 (en) * | 1989-07-06 | 1991-01-09 | Connaught Laboratories Limited | Tines structure of clinical applicator |
WO1996017648A1 (en) * | 1994-12-09 | 1996-06-13 | Novartis Ag | Transdermal system |
DE19525607A1 (en) * | 1995-07-14 | 1997-01-16 | Boehringer Ingelheim Kg | Transcorneal drug delivery system |
WO1998000193A1 (en) * | 1996-07-03 | 1998-01-08 | Altea Technologies, Inc. | Multiple mechanical microporation of skin or mucosa |
WO2000009184A1 (en) * | 1998-08-13 | 2000-02-24 | Imprint Pharmaceuticals Limited | Apparatus for delivering a substance having one or more needles driven at high velocity |
Non-Patent Citations (1)
Title |
---|
See also references of WO0166065A3 * |
Also Published As
Publication number | Publication date |
---|---|
WO2001066065A3 (en) | 2002-01-31 |
EP1276426A2 (en) | 2003-01-22 |
AU2001245472A1 (en) | 2001-09-17 |
WO2001066065A2 (en) | 2001-09-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20020920 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Free format text: AL;LT;LV;MK;RO;SI |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20080218 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61B 5/00 20060101ALI20080212BHEP Ipc: A61M 37/00 20060101AFI20080212BHEP |
|
17Q | First examination report despatched |
Effective date: 20081223 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20091001 |