JP5016926B2 - 架橋したヒアルロナンおよび/またはハイランに由来する粘着性ゲル、その調製および使用法 - Google Patents

架橋したヒアルロナンおよび/またはハイランに由来する粘着性ゲル、その調製および使用法 Download PDF

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Publication number
JP5016926B2
JP5016926B2 JP2006547530A JP2006547530A JP5016926B2 JP 5016926 B2 JP5016926 B2 JP 5016926B2 JP 2006547530 A JP2006547530 A JP 2006547530A JP 2006547530 A JP2006547530 A JP 2006547530A JP 5016926 B2 JP5016926 B2 JP 5016926B2
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gel
solution
dvs
polymer
ipc
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Japanese (ja)
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JP2007519779A (ja
Inventor
アデルヤ ケイ. レシチナー
ポール エー. コノウィッツ
バレンチナ バシリーバ
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Genzyme Corp
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Genzyme Corp
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2006547530A 2003-12-30 2004-12-30 架橋したヒアルロナンおよび/またはハイランに由来する粘着性ゲル、その調製および使用法 Expired - Lifetime JP5016926B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53342903P 2003-12-30 2003-12-30
US60/533,429 2003-12-30
PCT/US2004/043811 WO2005066215A1 (en) 2003-12-30 2004-12-30 Cohesive gels form cross-linked hyaluronan and/or hylan, their preparation and use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011169777A Division JP5680501B2 (ja) 2003-12-30 2011-08-03 架橋したヒアルロナンおよび/またはハイランに由来する粘着性ゲル、その調製および使用法

Publications (2)

Publication Number Publication Date
JP2007519779A JP2007519779A (ja) 2007-07-19
JP5016926B2 true JP5016926B2 (ja) 2012-09-05

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JP2006547530A Expired - Lifetime JP5016926B2 (ja) 2003-12-30 2004-12-30 架橋したヒアルロナンおよび/またはハイランに由来する粘着性ゲル、その調製および使用法
JP2011169777A Expired - Lifetime JP5680501B2 (ja) 2003-12-30 2011-08-03 架橋したヒアルロナンおよび/またはハイランに由来する粘着性ゲル、その調製および使用法

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JP2011169777A Expired - Lifetime JP5680501B2 (ja) 2003-12-30 2011-08-03 架橋したヒアルロナンおよび/またはハイランに由来する粘着性ゲル、その調製および使用法

Country Status (10)

Country Link
US (1) US20050142152A1 (enExample)
EP (1) EP1701981B1 (enExample)
JP (2) JP5016926B2 (enExample)
CN (1) CN100537606C (enExample)
AU (1) AU2004312532B2 (enExample)
BR (1) BRPI0418309B8 (enExample)
CA (1) CA2550718C (enExample)
IL (1) IL176465A (enExample)
MX (1) MXPA06007556A (enExample)
WO (1) WO2005066215A1 (enExample)

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Also Published As

Publication number Publication date
JP2007519779A (ja) 2007-07-19
MXPA06007556A (es) 2006-08-31
BRPI0418309A (pt) 2007-05-02
EP1701981B1 (en) 2017-06-07
BRPI0418309B8 (pt) 2021-05-25
CA2550718A1 (en) 2005-07-21
US20050142152A1 (en) 2005-06-30
WO2005066215A1 (en) 2005-07-21
AU2004312532A1 (en) 2005-07-21
BRPI0418309B1 (pt) 2016-08-02
EP1701981A1 (en) 2006-09-20
JP2012025955A (ja) 2012-02-09
CA2550718C (en) 2013-11-05
IL176465A0 (en) 2006-10-05
CN100537606C (zh) 2009-09-09
CN1902232A (zh) 2007-01-24
IL176465A (en) 2013-07-31
AU2004312532B2 (en) 2010-05-20
JP5680501B2 (ja) 2015-03-04

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