JP4932162B2 - 焦点検出装置とそれを用いた蛍光観察装置 - Google Patents

焦点検出装置とそれを用いた蛍光観察装置 Download PDF

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Publication number
JP4932162B2
JP4932162B2 JP2005012824A JP2005012824A JP4932162B2 JP 4932162 B2 JP4932162 B2 JP 4932162B2 JP 2005012824 A JP2005012824 A JP 2005012824A JP 2005012824 A JP2005012824 A JP 2005012824A JP 4932162 B2 JP4932162 B2 JP 4932162B2
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Japan
Prior art keywords
light
focus detection
objective lens
boundary surface
specimen
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Expired - Fee Related
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JP2005012824A
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Japanese (ja)
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JP2006201465A5 (enExample
JP2006201465A (ja
Inventor
雅善 唐澤
敦宏 土屋
貴 米山
健一 小山
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Olympus Corp
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Olympus Corp
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Priority to JP2005012824A priority Critical patent/JP4932162B2/ja
Priority to US11/328,028 priority patent/US7304282B2/en
Publication of JP2006201465A publication Critical patent/JP2006201465A/ja
Priority to US11/876,676 priority patent/US7612316B2/en
Publication of JP2006201465A5 publication Critical patent/JP2006201465A5/ja
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    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/0088—Inverse microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/244—Devices for focusing using image analysis techniques
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/245—Devices for focusing using auxiliary sources, detectors

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Microscoopes, Condenser (AREA)
  • Automatic Focus Adjustment (AREA)
JP2005012824A 2005-01-20 2005-01-20 焦点検出装置とそれを用いた蛍光観察装置 Expired - Fee Related JP4932162B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2005012824A JP4932162B2 (ja) 2005-01-20 2005-01-20 焦点検出装置とそれを用いた蛍光観察装置
US11/328,028 US7304282B2 (en) 2005-01-20 2006-01-09 Focus detection device and fluorescent observation device using the same
US11/876,676 US7612316B2 (en) 2005-01-20 2007-10-22 Focus detection device and fluorescent observation device using the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2005012824A JP4932162B2 (ja) 2005-01-20 2005-01-20 焦点検出装置とそれを用いた蛍光観察装置

Related Child Applications (1)

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JP2008036253A Division JP5289792B2 (ja) 2008-02-18 2008-02-18 焦点検出装置とそれを用いた蛍光観察装置

Publications (3)

Publication Number Publication Date
JP2006201465A JP2006201465A (ja) 2006-08-03
JP2006201465A5 JP2006201465A5 (enExample) 2008-03-06
JP4932162B2 true JP4932162B2 (ja) 2012-05-16

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JP2005012824A Expired - Fee Related JP4932162B2 (ja) 2005-01-20 2005-01-20 焦点検出装置とそれを用いた蛍光観察装置

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US (2) US7304282B2 (enExample)
JP (1) JP4932162B2 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1678544A1 (de) * 2003-09-25 2006-07-12 Leica Microsystems CMS GmbH Verfahren zur probenuntersuchung und mikroskop mit evaneszenter probenbeleuchtung
JP5087745B2 (ja) * 2005-09-26 2012-12-05 国立大学法人浜松医科大学 複数の観察手法を用いた顕微鏡細胞観察・検査システム
JP4663602B2 (ja) 2006-08-14 2011-04-06 オリンパス株式会社 自動合焦装置、顕微鏡および自動合焦方法
CN101583895B (zh) * 2007-01-19 2012-09-05 株式会社尼康 焦点检测装置和显微镜
JP2008276070A (ja) * 2007-05-02 2008-11-13 Olympus Corp 拡大撮像装置
US8324596B2 (en) 2008-07-25 2012-12-04 Hitachi High-Technologies Corporation Total internal reflection fluorescence (TIRF) observation device
US7883276B2 (en) * 2008-10-14 2011-02-08 Sonosite, Inc. Optical transmission coupling
CN102483509B (zh) * 2009-07-13 2015-04-22 株式会社尼康 三维方向漂移控制装置以及显微镜装置
TWI456254B (zh) * 2010-05-19 2014-10-11 Ind Tech Res Inst 螢光顯微影像系統
DK2663890T3 (en) * 2011-01-12 2015-11-30 Idea Machine Dev Design & Production Ltd COMPACT MICROSCOPY SYSTEM AND PROCEDURE
WO2015064098A1 (ja) 2013-10-30 2015-05-07 株式会社ニコン 全反射顕微鏡
EP3355038B1 (en) * 2017-01-25 2021-09-08 Specim, Spectral Imaging Oy Ltd Imaging apparatus and operating method
EP3614192A1 (en) * 2018-08-20 2020-02-26 Till GmbH Microscope device
DE112020000879T5 (de) * 2019-02-20 2021-11-11 Sony Group Corporation Mikroskopsystem, fokuseinstellprogramm und fokuseinstellsystem

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3708632B2 (ja) * 1996-07-10 2005-10-19 株式会社コーナン・メディカル 眼球撮影装置
US6594011B1 (en) * 2000-07-11 2003-07-15 Maven Technologies, Llc Imaging apparatus and method
JP2002156578A (ja) * 2000-11-20 2002-05-31 Olympus Optical Co Ltd 焦点検出装置、及びそれを備えた対物レンズ、光学顕微鏡又は光学検査装置
JP2002341234A (ja) * 2001-05-17 2002-11-27 Olympus Optical Co Ltd 顕微鏡用オートフォーカス装置
JP3995458B2 (ja) * 2001-12-07 2007-10-24 オリンパス株式会社 全反射蛍光顕微鏡
IL148664A0 (en) * 2002-03-13 2002-09-12 Yeda Res & Dev Auto-focusing method and device
JP2003270524A (ja) 2002-03-19 2003-09-25 Nikon Corp 焦点検出装置およびこれを備えた顕微鏡、および、焦点検出方法
JP4370554B2 (ja) * 2002-06-14 2009-11-25 株式会社ニコン オートフォーカス装置およびオートフォーカス付き顕微鏡
DE10309269B4 (de) * 2003-03-03 2005-06-02 Till Photonics Gmbh Vorrichtung für Totale Interne Reflexions-Mikroskopie

Also Published As

Publication number Publication date
US20060157637A1 (en) 2006-07-20
US20080179491A1 (en) 2008-07-31
US7612316B2 (en) 2009-11-03
JP2006201465A (ja) 2006-08-03
US7304282B2 (en) 2007-12-04

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