JP4776228B2 - Ｔヘルパー（ｔｈ）細胞の発生および機能を調節するための方法および組成物 - Google Patents

Ｔヘルパー（ｔｈ）細胞の発生および機能を調節するための方法および組成物 Download PDF

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JP4776228B2
JP4776228B2 JP2004521793A JP2004521793A JP4776228B2 JP 4776228 B2 JP4776228 B2 JP 4776228B2 JP 2004521793 A JP2004521793 A JP 2004521793A JP 2004521793 A JP2004521793 A JP 2004521793A JP 4776228 B2 JP4776228 B2 JP 4776228B2
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cells
cell
antibody
ifnγ
polypeptide
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JP2006507231A (ja
JP2006507231A5 (enExample
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マイケル グラズビー，
アンドレア ウースター，
デボラ エー． ヤング，
メリー コリンズ，
マシュー ジェイ． ウィッターズ，
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Harvard University
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]

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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2004521793A 2002-07-15 2003-07-15 Ｔヘルパー（ｔｈ）細胞の発生および機能を調節するための方法および組成物 Expired - Fee Related JP4776228B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39616002P 2002-07-15 2002-07-15
US60/396,160 2002-07-15
US40300102P 2002-08-12 2002-08-12
US60/403,001 2002-08-12
PCT/US2003/021975 WO2004007682A2 (en) 2002-07-15 2003-07-15 Methods and compositions for modulating t helper (th) cell development and function

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JP2009270851A Division JP2010090133A (ja) 2002-07-15 2009-11-27 Ｔヘルパー（ｔｈ）細胞の発生および機能を調節するための方法および組成物

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JP2006507231A JP2006507231A (ja) 2006-03-02
JP2006507231A5 JP2006507231A5 (enExample) 2006-09-21
JP4776228B2 true JP4776228B2 (ja) 2011-09-21

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JP2009270851A Pending JP2010090133A (ja) 2002-07-15 2009-11-27 Ｔヘルパー（ｔｈ）細胞の発生および機能を調節するための方法および組成物

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US (2) US7314623B2 (enExample)
EP (1) EP1553982A4 (enExample)
JP (2) JP4776228B2 (enExample)
KR (1) KR20050037552A (enExample)
CN (1) CN1688340A (enExample)
AU (1) AU2003251900B2 (enExample)
BR (1) BR0312738A (enExample)
CA (1) CA2491320A1 (enExample)
EA (1) EA011686B1 (enExample)
IL (2) IL165990A0 (enExample)
MX (1) MXPA05000655A (enExample)
NO (1) NO20050717L (enExample)
WO (1) WO2004007682A2 (enExample)
ZA (1) ZA200500480B (enExample)

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WO2004007682A2 (en) 2004-01-22
MXPA05000655A (es) 2006-02-22
IL165990A0 (en) 2006-01-15
US20090197803A1 (en) 2009-08-06
WO2004007682A3 (en) 2004-12-29
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BR0312738A (pt) 2007-06-26
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US20040136954A1 (en) 2004-07-15
CA2491320A1 (en) 2004-01-22
CN1688340A (zh) 2005-10-26
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