JP4602076B2 - 抗ウイルス剤としてのピラゾロ［１，５ａ］ピリミジン化合物 - Google Patents

抗ウイルス剤としてのピラゾロ［１，５ａ］ピリミジン化合物 Download PDF

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Publication number
JP4602076B2
JP4602076B2 JP2004509684A JP2004509684A JP4602076B2 JP 4602076 B2 JP4602076 B2 JP 4602076B2 JP 2004509684 A JP2004509684 A JP 2004509684A JP 2004509684 A JP2004509684 A JP 2004509684A JP 4602076 B2 JP4602076 B2 JP 4602076B2
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Prior art keywords
mmol
phenyl
pyrazolo
pyrimidine
cyclohexyl
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Expired - Fee Related
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JP2004509684A
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Japanese (ja)
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JP2005533040A (ja
JP2005533040A5 (OSRAM
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ジェラルド ダブリュー．， ジュニア シップス，
クリスティン イー． ロスナー，
ジャネタ ポポビシ−ミュラー，
ヨンギ デン，
トン ワン，
パトリック ジェイ． カーラン，
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Neogenesis Pharmaceuticals Inc
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Neogenesis Pharmaceuticals Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2004509684A 2002-06-04 2003-06-02 抗ウイルス剤としてのピラゾロ［１，５ａ］ピリミジン化合物 Expired - Fee Related JP4602076B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38583702P 2002-06-04 2002-06-04
PCT/US2003/017368 WO2003101993A1 (en) 2002-06-04 2003-06-02 Pyrazolo` 1,5a! pyrimidine compounds as antiviral agents

Publications (3)

Publication Number Publication Date
JP2005533040A JP2005533040A (ja) 2005-11-04
JP2005533040A5 JP2005533040A5 (OSRAM) 2006-04-27
JP4602076B2 true JP4602076B2 (ja) 2010-12-22

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JP2004509684A Expired - Fee Related JP4602076B2 (ja) 2002-06-04 2003-06-02 抗ウイルス剤としてのピラゾロ［１，５ａ］ピリミジン化合物

Country Status (11)

Country Link
US (1) US7196111B2 (OSRAM)
EP (1) EP1511751B1 (OSRAM)
JP (1) JP4602076B2 (OSRAM)
CN (1) CN1671710A (OSRAM)
AT (1) ATE389656T1 (OSRAM)
AU (1) AU2003240488A1 (OSRAM)
CA (1) CA2487211C (OSRAM)
DE (1) DE60319820T2 (OSRAM)
ES (1) ES2304511T3 (OSRAM)
MX (1) MXPA04012245A (OSRAM)
WO (1) WO2003101993A1 (OSRAM)

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CA2487211A1 (en) 2003-12-11
CN1671710A (zh) 2005-09-21
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AU2003240488A1 (en) 2003-12-19
US20040038993A1 (en) 2004-02-26
DE60319820D1 (de) 2008-04-30
WO2003101993A1 (en) 2003-12-11
CA2487211C (en) 2010-09-14
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