JP4601143B2 - 新規酵素遺伝子およびその発現産物 - Google Patents

新規酵素遺伝子およびその発現産物 Download PDF

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Publication number
JP4601143B2
JP4601143B2 JP2000290679A JP2000290679A JP4601143B2 JP 4601143 B2 JP4601143 B2 JP 4601143B2 JP 2000290679 A JP2000290679 A JP 2000290679A JP 2000290679 A JP2000290679 A JP 2000290679A JP 4601143 B2 JP4601143 B2 JP 4601143B2
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Japan
Prior art keywords
gene
gfat1l
protein
present
gfat
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Expired - Fee Related
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JP2000290679A
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English (en)
Japanese (ja)
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JP2002065284A5 (https=
JP2002065284A (ja
Inventor
力 藤原
考史 岡本
正史 新美
弘之 急式
恵史 山本
篤則 植山
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
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Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2000290679A priority Critical patent/JP4601143B2/ja
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to ES01938602T priority patent/ES2312442T3/es
Priority to CNB018111114A priority patent/CN100390286C/zh
Priority to PCT/JP2001/004941 priority patent/WO2001096574A1/ja
Priority to PT01938602T priority patent/PT1291429E/pt
Priority to ARP010102776A priority patent/AR029130A1/es
Priority to EP01938602A priority patent/EP1291429B1/en
Priority to AU6424501A priority patent/AU6424501A/xx
Priority to CA2412880A priority patent/CA2412880C/en
Priority to US10/297,599 priority patent/US7091018B2/en
Priority to AT01938602T priority patent/ATE407212T1/de
Priority to KR1020027016418A priority patent/KR100882407B1/ko
Priority to DK01938602T priority patent/DK1291429T3/da
Priority to DE60135650T priority patent/DE60135650D1/de
Priority to AU2001264245A priority patent/AU2001264245B2/en
Priority to TW090125551A priority patent/TWI232883B/zh
Publication of JP2002065284A publication Critical patent/JP2002065284A/ja
Publication of JP2002065284A5 publication Critical patent/JP2002065284A5/ja
Application granted granted Critical
Publication of JP4601143B2 publication Critical patent/JP4601143B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2000290679A 2000-06-13 2000-09-25 新規酵素遺伝子およびその発現産物 Expired - Fee Related JP4601143B2 (ja)

Priority Applications (16)

Application Number Priority Date Filing Date Title
JP2000290679A JP4601143B2 (ja) 2000-06-13 2000-09-25 新規酵素遺伝子およびその発現産物
DK01938602T DK1291429T3 (da) 2000-06-13 2001-06-12 Glutamin-fruktose-6-fosfat-amidotransferase-splice-variant og dets ekspressionsprodukt
PCT/JP2001/004941 WO2001096574A1 (en) 2000-06-13 2001-06-12 Novel enzyme gene and its expression product
PT01938602T PT1291429E (pt) 2000-06-13 2001-06-12 Variante de splicing da glutamina-frutose-6-fosfatoamidotransferase e seu produto de expressão
ARP010102776A AR029130A1 (es) 2000-06-13 2001-06-12 Gen enzimatico y sus productos de expresion
EP01938602A EP1291429B1 (en) 2000-06-13 2001-06-12 Glutamine fructose-6-phosphate amidotransferase splice variant and its expression product
AU6424501A AU6424501A (en) 2000-06-13 2001-06-12 Novel enzyme gene and its expression product
CA2412880A CA2412880C (en) 2000-06-13 2001-06-12 Glutamine fructose-6-phosphate amidotransferase splice variant and its expression product
ES01938602T ES2312442T3 (es) 2000-06-13 2001-06-12 Variante alternativa de corte y empalme de glutamina fructosa-6-fosfato amidotransferasa y su producto de expresion.
AT01938602T ATE407212T1 (de) 2000-06-13 2001-06-12 Spleissvariante der glutamine fructose-6- phosphate amidotransferase und dessen expressionsprodukt
KR1020027016418A KR100882407B1 (ko) 2000-06-13 2001-06-12 신규 효소 유전자 및 그의 발현 생산물
CNB018111114A CN100390286C (zh) 2000-06-13 2001-06-12 新酶基因及其表达产物
DE60135650T DE60135650D1 (de) 2000-06-13 2001-06-12 Amidotransferase und dessen expressionsprodukt
AU2001264245A AU2001264245B2 (en) 2000-06-13 2001-06-12 Novel enzyme gene and its expression product
US10/297,599 US7091018B2 (en) 2000-06-13 2001-06-12 Enzyme gene and its expression product
TW090125551A TWI232883B (en) 2000-06-13 2001-10-16 Novel enzyme gene and expression product thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000-176631 2000-06-13
JP2000176631 2000-06-13
JP2000290679A JP4601143B2 (ja) 2000-06-13 2000-09-25 新規酵素遺伝子およびその発現産物

Publications (3)

Publication Number Publication Date
JP2002065284A JP2002065284A (ja) 2002-03-05
JP2002065284A5 JP2002065284A5 (https=) 2007-09-13
JP4601143B2 true JP4601143B2 (ja) 2010-12-22

Family

ID=26593812

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000290679A Expired - Fee Related JP4601143B2 (ja) 2000-06-13 2000-09-25 新規酵素遺伝子およびその発現産物

Country Status (15)

Country Link
US (1) US7091018B2 (https=)
EP (1) EP1291429B1 (https=)
JP (1) JP4601143B2 (https=)
KR (1) KR100882407B1 (https=)
CN (1) CN100390286C (https=)
AR (1) AR029130A1 (https=)
AT (1) ATE407212T1 (https=)
AU (2) AU2001264245B2 (https=)
CA (1) CA2412880C (https=)
DE (1) DE60135650D1 (https=)
DK (1) DK1291429T3 (https=)
ES (1) ES2312442T3 (https=)
PT (1) PT1291429E (https=)
TW (1) TWI232883B (https=)
WO (1) WO2001096574A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602006021421D1 (de) * 2005-06-20 2011-06-01 Exelixis Inc Ngsverfahren
JP2009509557A (ja) * 2005-10-05 2009-03-12 バイエル・クロップサイエンス・アーゲー 改善されたヒアルロン酸産生方法および手段
RU2009103003A (ru) * 2006-06-30 2010-08-10 Хоккайдо Систем Сайенс Ко., Лтд. (Jp) Композиция для трансфекции нуклеиновой кислоты
CN103301447B (zh) * 2013-06-25 2014-12-31 哈尔滨医科大学 DNA-PKcs在制备改变肿瘤细胞对MTX耐药性的药物中的应用
CN112980914A (zh) * 2019-12-12 2021-06-18 中国科学院大连化学物理研究所 Gfpt1基因作为靶点在筛选抗肿瘤药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993021330A1 (en) * 1992-04-22 1993-10-28 Zymogenetics, Inc. Human glutamine:fructose-6-phosphate amino-transferase
JPH1018683A (ja) * 1996-06-29 1998-01-20 Tesco Joho Center:Kk 吊下扉のレール装置
CA2212786A1 (en) * 1996-08-13 1998-02-13 Takeda Chemical Industries, Ltd. Novel glutamine:fructose-6-phosphate amidotransferase, its production and use
JP4175680B2 (ja) * 1996-08-13 2008-11-05 武田薬品工業株式会社 新規タンパク質およびそのｄｎａ
AU2216300A (en) * 1998-12-22 2000-07-12 G.D. Searle & Co. Glutamine: fructose-6-phosphate aminotransferase ii enzyme and their encoding nucleic acids

Also Published As

Publication number Publication date
KR20030011868A (ko) 2003-02-11
CA2412880A1 (en) 2002-12-13
DE60135650D1 (de) 2008-10-16
CN1436239A (zh) 2003-08-13
CA2412880C (en) 2010-05-04
KR100882407B1 (ko) 2009-02-05
JP2002065284A (ja) 2002-03-05
US20040132020A1 (en) 2004-07-08
PT1291429E (pt) 2008-12-15
EP1291429A1 (en) 2003-03-12
DK1291429T3 (da) 2009-01-19
ES2312442T3 (es) 2009-03-01
CN100390286C (zh) 2008-05-28
AR029130A1 (es) 2003-06-04
TWI232883B (en) 2005-05-21
US7091018B2 (en) 2006-08-15
EP1291429A4 (en) 2004-05-26
WO2001096574A1 (en) 2001-12-20
ATE407212T1 (de) 2008-09-15
AU2001264245B2 (en) 2006-04-27
AU6424501A (en) 2001-12-24
EP1291429B1 (en) 2008-09-03

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