JP4486187B2 - 新規ｇ蛋白質共役型レセプター蛋白質、そのｄｎａおよびそのリガンド - Google Patents

新規ｇ蛋白質共役型レセプター蛋白質、そのｄｎａおよびそのリガンド Download PDF

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Publication number
JP4486187B2
JP4486187B2 JP27622599A JP27622599A JP4486187B2 JP 4486187 B2 JP4486187 B2 JP 4486187B2 JP 27622599 A JP27622599 A JP 27622599A JP 27622599 A JP27622599 A JP 27622599A JP 4486187 B2 JP4486187 B2 JP 4486187B2
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present
protein
seq
ligand
receptor protein
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Expired - Fee Related
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JP27622599A
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English (en)
Japanese (ja)
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JP2000312590A (ja
JP2000312590A5 (cg-RX-API-DMAC7.html
Inventor
卓也 渡辺
寧子 寺尾
靖 新谷
徹也 大瀧
貴美子 金橋
千恵子 北田
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Takeda Pharmaceutical Co Ltd
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Takeda Pharmaceutical Co Ltd
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Priority to JP27622599A priority Critical patent/JP4486187B2/ja
Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Priority to PL99347553A priority patent/PL347553A1/xx
Priority to BR9914835-8A priority patent/BR9914835A/pt
Priority to AU62306/99A priority patent/AU6230699A/en
Priority to KR1020017005344A priority patent/KR20010085974A/ko
Priority to CA002347294A priority patent/CA2347294A1/en
Priority to SK550-2001A priority patent/SK5502001A3/sk
Priority to IL14242899A priority patent/IL142428A0/xx
Priority to DE69938666T priority patent/DE69938666D1/de
Priority to EP99949421A priority patent/EP1126028B1/en
Priority to CN99812722A priority patent/CN1324405A/zh
Priority to AT99949421T priority patent/ATE394485T1/de
Priority to PCT/JP1999/005905 priority patent/WO2000024890A1/ja
Priority to NZ510977A priority patent/NZ510977A/xx
Priority to US09/830,428 priority patent/US6699965B1/en
Priority to CZ20011358A priority patent/CZ20011358A3/cs
Priority to HU0104937A priority patent/HUP0104937A2/hu
Priority to IDW20010936A priority patent/ID28288A/id
Publication of JP2000312590A publication Critical patent/JP2000312590A/ja
Priority to NO20012059A priority patent/NO20012059L/no
Priority to US10/771,417 priority patent/US7314754B2/en
Publication of JP2000312590A5 publication Critical patent/JP2000312590A5/ja
Priority to US11/976,414 priority patent/US7608409B2/en
Application granted granted Critical
Publication of JP4486187B2 publication Critical patent/JP4486187B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
JP27622599A 1998-10-27 1999-09-29 新規ｇ蛋白質共役型レセプター蛋白質、そのｄｎａおよびそのリガンド Expired - Fee Related JP4486187B2 (ja)

Priority Applications (21)

Application Number Priority Date Filing Date Title
JP27622599A JP4486187B2 (ja) 1998-10-27 1999-09-29 新規ｇ蛋白質共役型レセプター蛋白質、そのｄｎａおよびそのリガンド
NZ510977A NZ510977A (en) 1998-10-27 1999-10-26 Novel G protein-coupled receptor proteins, DNAs thereof and ligands to the same
AU62306/99A AU6230699A (en) 1998-10-27 1999-10-26 Novel g protein-coupled receptor proteins, dnas thereof and ligands to the same
KR1020017005344A KR20010085974A (ko) 1998-10-27 1999-10-26 신규 ｇ 단백질 공액형 리셉터 단백질, 그 ｄｎａ 및 그에대한 리간드
CA002347294A CA2347294A1 (en) 1998-10-27 1999-10-26 Novel g protein coupled receptor protein, dna and its ligand
SK550-2001A SK5502001A3 (en) 1998-10-27 1999-10-26 Novel g protein-coupled receptor proteins, dnas thereof and ligands to the same
IL14242899A IL142428A0 (en) 1998-10-27 1999-10-26 Novel g protein-couple receptor proteins, dna's thereof and ligands to the same
DE69938666T DE69938666D1 (de) 1998-10-27 1999-10-26 Neue g protein-gekoppelte rezeptor proteine, dnas davon und liganden für diese
EP99949421A EP1126028B1 (en) 1998-10-27 1999-10-26 Novel g protein-coupled receptor proteins, dnas thereof and ligands to the same
BR9914835-8A BR9914835A (pt) 1998-10-27 1999-10-26 Proteìna e seus sais, método para fabricar a mesma, anticorpo para a mesma, ligando à mesma, método para determinar o mesmo, peptìdeo parcial da proteìna ou seus ésteres ou suas amidas ou seus sais, polinucleotìdeo, vetor recombinante, transformante, composição de diagnóstico, composição farmacêutica, composto ou seus sais, método para triar o mesmo, kit para triar o mesmo, método para quantificar a proteìna, peptìdeo, uma amida deste, um éster deste ou um sal deste, amida ou sal do peptìdeo, método para triagem, e, kit para filtragem
AT99949421T ATE394485T1 (de) 1998-10-27 1999-10-26 Neue g protein-gekoppelte rezeptor proteine, dnas davon und liganden für diese
PCT/JP1999/005905 WO2000024890A1 (en) 1998-10-27 1999-10-26 Novel g protein-coupled receptor proteins, dnas thereof and ligands to the same
PL99347553A PL347553A1 (en) 1998-10-27 1999-10-26 Novel g protein-coupled receptor proteins, dnas thereof and ligands to the same
US09/830,428 US6699965B1 (en) 1998-10-27 1999-10-26 Peptides that activate the G-protein coupled receptor protein, 0T7T175
CN99812722A CN1324405A (zh) 1998-10-27 1999-10-26 新型g蛋白偶联型受体蛋白、dna及其配体
HU0104937A HUP0104937A2 (hu) 1998-10-27 1999-10-26 Új, G-fehérjéhez kapcsolt receptorfehérje, DNS-e és ligandja
CZ20011358A CZ20011358A3 (cs) 1998-10-27 1999-10-26 Nový receptorový protein spojený s G proteinem, DNA a její ligand
IDW20010936A ID28288A (id) 1998-10-27 1999-10-27 Protein reseptor yang tergandeng protein g baru, dna dan ligannya
NO20012059A NO20012059L (no) 1998-10-27 2001-04-26 Nye G-protein-koplede reseptorproteiner, DNA derav og ligander til det samme
US10/771,417 US7314754B2 (en) 1998-10-27 2004-02-05 Polynucleotide encoding the hOT7T175 G protein coupled receptor
US11/976,414 US7608409B2 (en) 1998-10-27 2007-10-24 Screening assay using G-protein coupled receptor protein OT7T175

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP30594998 1998-10-27
JP2771099 1999-02-04
JP10-305949 1999-03-04
JP11-27710 1999-03-04
JP5720799 1999-03-04
JP11-57207 1999-03-04
JP27622599A JP4486187B2 (ja) 1998-10-27 1999-09-29 新規ｇ蛋白質共役型レセプター蛋白質、そのｄｎａおよびそのリガンド

Publications (3)

Publication Number Publication Date
JP2000312590A JP2000312590A (ja) 2000-11-14
JP2000312590A5 JP2000312590A5 (cg-RX-API-DMAC7.html) 2006-11-02
JP4486187B2 true JP4486187B2 (ja) 2010-06-23

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Family Applications (1)

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JP27622599A Expired - Fee Related JP4486187B2 (ja) 1998-10-27 1999-09-29 新規ｇ蛋白質共役型レセプター蛋白質、そのｄｎａおよびそのリガンド

Country Status (19)

Country Link
US (3) US6699965B1 (cg-RX-API-DMAC7.html)
EP (1) EP1126028B1 (cg-RX-API-DMAC7.html)
JP (1) JP4486187B2 (cg-RX-API-DMAC7.html)
KR (1) KR20010085974A (cg-RX-API-DMAC7.html)
CN (1) CN1324405A (cg-RX-API-DMAC7.html)
AT (1) ATE394485T1 (cg-RX-API-DMAC7.html)
AU (1) AU6230699A (cg-RX-API-DMAC7.html)
BR (1) BR9914835A (cg-RX-API-DMAC7.html)
CA (1) CA2347294A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ20011358A3 (cg-RX-API-DMAC7.html)
DE (1) DE69938666D1 (cg-RX-API-DMAC7.html)
HU (1) HUP0104937A2 (cg-RX-API-DMAC7.html)
ID (1) ID28288A (cg-RX-API-DMAC7.html)
IL (1) IL142428A0 (cg-RX-API-DMAC7.html)
NO (1) NO20012059L (cg-RX-API-DMAC7.html)
NZ (1) NZ510977A (cg-RX-API-DMAC7.html)
PL (1) PL347553A1 (cg-RX-API-DMAC7.html)
SK (1) SK5502001A3 (cg-RX-API-DMAC7.html)
WO (1) WO2000024890A1 (cg-RX-API-DMAC7.html)

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WO2000050563A2 (en) * 1999-02-24 2000-08-31 Merck & Co., Inc. G protein-coupled receptor resembling galanin receptors
WO2001075104A1 (fr) * 2000-03-30 2001-10-11 Takeda Chemical Industries, Ltd. Nouvelle proteine, adn codant pour celle-ci, et son procede de production
EP1168259A3 (en) 2000-06-28 2003-12-17 Hitachi, Ltd. Data management method and system for IC card
EP1314781A4 (en) * 2000-08-30 2004-11-03 Endo Yaeta Dr DESIGN AND CONSTRUCTION OF A TRANSCRIPTION MODEL OF ACELLULAR PROTEIN SYNTHESIS, AND DISCONTINUOUS DILUTION METHOD FOR USE IN SYNTHESIS OF ACELLULAR WHEAT GERM PROTEIN
JP2002109169A (ja) 2000-09-29 2002-04-12 Hitachi Ltd 作業支援方法並びにシステム及び作業支援方法を記録した記録媒体
CA2430934C (en) 2000-12-01 2011-06-21 Takeda Chemical Industries, Ltd. A method of producing sustained-release preparations of a bioactive substance using high-pressure gas
US20050075494A1 (en) * 2000-12-18 2005-04-07 Liu Qingyun Isolated nucleic acid molecules encoding a human and mouse g protein-coupled receptor-gpr54: encoded proteins, cells transformed therewith and uses thereof
WO2002057309A1 (fr) * 2001-01-18 2002-07-25 Takeda Chemical Industries, Ltd. Nouvelle proteine receptrice couplee a la proteine g et adn de cette proteine
WO2002072816A1 (fr) * 2001-02-26 2002-09-19 Takeda Chemical Industries, Ltd. Proteine de recepteur murin de type kiss-1 et adn correspondant
WO2002083735A1 (fr) * 2001-04-06 2002-10-24 Takeda Chemical Industries, Ltd. Nouvelle proteine receptrice et son adn
AU2008201996B2 (en) * 2001-09-18 2011-02-10 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
JP2005536439A (ja) 2001-09-18 2005-12-02 ジェネンテック・インコーポレーテッド 腫瘍の診断及び治療のための組成物と方法
EP1428835B1 (en) * 2001-09-19 2007-04-18 Takeda Pharmaceutical Company Limited Antibody against metastin and use of the same in the diagnosis of pregnancy
CA2472423A1 (en) * 2002-01-11 2003-07-24 Takeda Chemical Industries, Ltd. Process for producing kiss-1 peptide
WO2004024072A2 (en) * 2002-09-11 2004-03-25 Genentech, Inc. Novel compositions and methods for the treatment of immune related diseases
AU2003292696A1 (en) 2002-12-26 2004-08-10 Takeda Pharmaceutical Company Limited Metastin derivative and use thereof
US6800611B2 (en) 2003-01-06 2004-10-05 Takeda Chemical Industries, Ltd. Metastin derivatives and their use
CA2518541C (en) * 2003-03-12 2013-05-21 Takeda Pharmaceutical Company Limited Gonadal function improving agents
JP4639052B2 (ja) * 2003-03-12 2011-02-23 武田薬品工業株式会社 性腺機能改善剤
EP1464652A1 (en) * 2003-04-02 2004-10-06 Institut National De La Sante Et De La Recherche Medicale (Inserm) GPR54 receptor agonist and antagonist useful for the treatment of gonadotropin related diseases
WO2004096855A2 (en) * 2003-04-28 2004-11-11 Wyeth Methods utilising g-protein coupled receptor 54
WO2004101747A2 (en) * 2003-05-07 2004-11-25 The General Hospital Corporation Identification and use of gpr54 and its ligands for reproductive disorders and contraception
WO2005040833A1 (en) * 2003-10-21 2005-05-06 Bayer Healthcare Ag Regulation of human metastin recognising receptors
AR049938A1 (es) 2004-06-25 2006-09-13 Takeda Pharmaceutical Derivados de metastina y utilizacion de los mismos
US20090099334A1 (en) * 2005-12-22 2009-04-16 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
US8404643B2 (en) * 2005-12-22 2013-03-26 Takeda Pharmaceutical Company Limited Metastin derivatives and use thereof
AR058584A1 (es) * 2005-12-22 2008-02-13 Takeda Pharmaceutical Derivados de metastina y uso de los mismos
ITMI20061607A1 (it) 2006-08-09 2008-02-10 Maria Vincenza Carriero Peptidi con attivita farmacologica
TWI404726B (zh) 2006-10-25 2013-08-11 Takeda Pharmaceutical 腫瘤轉移抑制素衍生物及其用途
US20110118172A1 (en) * 2008-04-24 2011-05-19 Takeda Pharmaceutical Company Limited Metastin derivative and use thereof
EP2314609B1 (en) 2008-07-30 2016-11-30 Takeda Pharmaceutical Company Limited Metastin derivative and use thereof
EP2350118B1 (en) * 2008-09-19 2016-03-30 Nektar Therapeutics Carbohydrate-based drug delivery polymers and conjugates thereof
US20110171160A1 (en) * 2008-09-19 2011-07-14 Nektar Therapeutics Polymer conjugates of kiss1 peptides
US8716228B2 (en) 2009-05-27 2014-05-06 Yeda Research And Development Co. Ltd. GPR54 agonists or antagonists for treatment of diseases presenting behavioral abnormalities
US20150157619A1 (en) 2012-07-10 2015-06-11 Takeda Pharmaceutical Company Limited Pharmaceutical preparation for injection
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CN109212217B (zh) * 2018-11-07 2021-09-10 李玉民 基于amy1a蛋白胃癌检测试剂盒及其使用方法

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CA2518541C (en) * 2003-03-12 2013-05-21 Takeda Pharmaceutical Company Limited Gonadal function improving agents

Also Published As

Publication number Publication date
JP2000312590A (ja) 2000-11-14
DE69938666D1 (de) 2008-06-19
BR9914835A (pt) 2002-06-18
NZ510977A (en) 2002-10-25
KR20010085974A (ko) 2001-09-07
HUP0104937A2 (hu) 2002-04-29
PL347553A1 (en) 2002-04-08
NO20012059L (no) 2001-06-26
US20040180407A1 (en) 2004-09-16
EP1126028B1 (en) 2008-05-07
US20080131976A1 (en) 2008-06-05
IL142428A0 (en) 2002-03-10
US7608409B2 (en) 2009-10-27
CZ20011358A3 (cs) 2001-08-15
ATE394485T1 (de) 2008-05-15
EP1126028A1 (en) 2001-08-22
ID28288A (id) 2001-05-10
WO2000024890A1 (en) 2000-05-04
US7314754B2 (en) 2008-01-01
US6699965B1 (en) 2004-03-02
SK5502001A3 (en) 2002-01-07
NO20012059D0 (no) 2001-04-26
EP1126028A4 (en) 2002-11-27
AU6230699A (en) 2000-05-15
CA2347294A1 (en) 2000-05-04
CN1324405A (zh) 2001-11-28

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