JP4241301B2 - 免疫学的測定用試薬 - Google Patents
免疫学的測定用試薬 Download PDFInfo
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- JP4241301B2 JP4241301B2 JP2003340028A JP2003340028A JP4241301B2 JP 4241301 B2 JP4241301 B2 JP 4241301B2 JP 2003340028 A JP2003340028 A JP 2003340028A JP 2003340028 A JP2003340028 A JP 2003340028A JP 4241301 B2 JP4241301 B2 JP 4241301B2
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- 125000006165 cyclic alkyl group Chemical group 0.000 description 1
- ZZTURJAZCMUWEP-UHFFFAOYSA-N diaminomethylideneazanium;hydrogen sulfate Chemical compound NC(N)=N.OS(O)(=O)=O ZZTURJAZCMUWEP-UHFFFAOYSA-N 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
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- ZAFFWOKULJCCSA-UHFFFAOYSA-N ethyl 2-methylprop-2-enoate;trimethylazanium;chloride Chemical compound [Cl-].C[NH+](C)C.CCOC(=O)C(C)=C ZAFFWOKULJCCSA-UHFFFAOYSA-N 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 229960000789 guanidine hydrochloride Drugs 0.000 description 1
- NDEMNVPZDAFUKN-UHFFFAOYSA-N guanidine;nitric acid Chemical compound NC(N)=N.O[N+]([O-])=O.O[N+]([O-])=O NDEMNVPZDAFUKN-UHFFFAOYSA-N 0.000 description 1
- PJJJBBJSCAKJQF-UHFFFAOYSA-N guanidinium chloride Chemical compound [Cl-].NC(N)=[NH2+] PJJJBBJSCAKJQF-UHFFFAOYSA-N 0.000 description 1
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- 229940083094 guanine derivative acting on arteriolar smooth muscle Drugs 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
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- VQGWOOIHSXNRPW-UHFFFAOYSA-N n-butyl-2-methylprop-2-enamide Chemical compound CCCCNC(=O)C(C)=C VQGWOOIHSXNRPW-UHFFFAOYSA-N 0.000 description 1
- YRVUCYWJQFRCOB-UHFFFAOYSA-N n-butylprop-2-enamide Chemical compound CCCCNC(=O)C=C YRVUCYWJQFRCOB-UHFFFAOYSA-N 0.000 description 1
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- XQPVIMDDIXCFFS-UHFFFAOYSA-N n-dodecylprop-2-enamide Chemical compound CCCCCCCCCCCCNC(=O)C=C XQPVIMDDIXCFFS-UHFFFAOYSA-N 0.000 description 1
- JKZQBSUPPNQHTK-UHFFFAOYSA-N n-ethyl-2-methylideneoctanamide Chemical compound CCCCCCC(=C)C(=O)NCC JKZQBSUPPNQHTK-UHFFFAOYSA-N 0.000 description 1
- ZIWDVJPPVMGJGR-UHFFFAOYSA-N n-ethyl-2-methylprop-2-enamide Chemical compound CCNC(=O)C(C)=C ZIWDVJPPVMGJGR-UHFFFAOYSA-N 0.000 description 1
- YPHQUSNPXDGUHL-UHFFFAOYSA-N n-methylprop-2-enamide Chemical compound CNC(=O)C=C YPHQUSNPXDGUHL-UHFFFAOYSA-N 0.000 description 1
- CNWVYEGPPMQTKA-UHFFFAOYSA-N n-octadecylprop-2-enamide Chemical compound CCCCCCCCCCCCCCCCCCNC(=O)C=C CNWVYEGPPMQTKA-UHFFFAOYSA-N 0.000 description 1
- 125000003935 n-pentoxy group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])O* 0.000 description 1
- 238000004848 nephelometry Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
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- 239000001301 oxygen Substances 0.000 description 1
- 229940055729 papain Drugs 0.000 description 1
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- PLPHXVSTHYOUJO-UHFFFAOYSA-N pent-2-en-2-ylbenzene Chemical compound CCC=C(C)C1=CC=CC=C1 PLPHXVSTHYOUJO-UHFFFAOYSA-N 0.000 description 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 description 1
- 229940111202 pepsin Drugs 0.000 description 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 description 1
- 125000000286 phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000004344 phenylpropyl group Chemical group 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- LPUCYUBAJZSGLI-UHFFFAOYSA-N prop-1-enylbenzene;trimethylazanium;bromide Chemical compound [Br-].C[NH+](C)C.CC=CC1=CC=CC=C1 LPUCYUBAJZSGLI-UHFFFAOYSA-N 0.000 description 1
- NHARPDSAXCBDDR-UHFFFAOYSA-N propyl 2-methylprop-2-enoate Chemical compound CCCOC(=O)C(C)=C NHARPDSAXCBDDR-UHFFFAOYSA-N 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000005215 recombination Methods 0.000 description 1
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- ZNJHFNUEQDVFCJ-UHFFFAOYSA-M sodium;2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid;hydroxide Chemical compound [OH-].[Na+].OCCN1CCN(CCS(O)(=O)=O)CC1 ZNJHFNUEQDVFCJ-UHFFFAOYSA-M 0.000 description 1
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 150000003440 styrenes Chemical class 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- AIUAMYPYEUQVEM-UHFFFAOYSA-N trimethyl(2-prop-2-enoyloxyethyl)azanium Chemical compound C[N+](C)(C)CCOC(=O)C=C AIUAMYPYEUQVEM-UHFFFAOYSA-N 0.000 description 1
- USFMMZYROHDWPJ-UHFFFAOYSA-N trimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azanium Chemical compound CC(=C)C(=O)OCC[N+](C)(C)C USFMMZYROHDWPJ-UHFFFAOYSA-N 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 238000004879 turbidimetry Methods 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
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- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003340028A JP4241301B2 (ja) | 2003-09-30 | 2003-09-30 | 免疫学的測定用試薬 |
| US10/867,912 US7279339B2 (en) | 2003-09-30 | 2004-06-15 | Reagent for an immunoassay |
| US11/394,463 US20060172351A1 (en) | 2003-09-30 | 2006-03-30 | Reagent for an immunoassay |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003340028A JP4241301B2 (ja) | 2003-09-30 | 2003-09-30 | 免疫学的測定用試薬 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005106609A JP2005106609A (ja) | 2005-04-21 |
| JP2005106609A5 JP2005106609A5 (enExample) | 2006-07-06 |
| JP4241301B2 true JP4241301B2 (ja) | 2009-03-18 |
Family
ID=34373384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003340028A Expired - Lifetime JP4241301B2 (ja) | 2003-09-30 | 2003-09-30 | 免疫学的測定用試薬 |
Country Status (2)
| Country | Link |
|---|---|
| US (2) | US7279339B2 (enExample) |
| JP (1) | JP4241301B2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012133482A1 (ja) | 2011-03-28 | 2012-10-04 | 積水メディカル株式会社 | Psaの測定方法及びその試薬 |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080044926A1 (en) * | 2004-12-24 | 2008-02-21 | Daiichi Pure Chemicals Co., | Reagent for Assaying Antigen and Method of Assaying Antigen |
| GB2432211B (en) * | 2005-11-12 | 2009-04-22 | Platform Diagnostics Ltd | Agglutination based assay system |
| JP5426881B2 (ja) | 2005-11-12 | 2014-02-26 | プラットフォーム・ダイアグノスティクス・リミテッド | 凝集アッセイ |
| WO2007074860A1 (ja) * | 2005-12-28 | 2007-07-05 | Sekisui Medical Co., Ltd. | 凝集測定用試薬及び凝集測定方法 |
| WO2007114337A1 (ja) * | 2006-03-31 | 2007-10-11 | Nissui Pharmaceutical Co., Ltd., | 免疫凝集反応試薬キット及び抗原の測定方法 |
| JP4982107B2 (ja) * | 2006-04-28 | 2012-07-25 | アルフレッサファーマ株式会社 | 免疫学的微小粒子の凝集反応を用いる検体の測定方法および測定用キット |
| US20100240150A1 (en) * | 2007-11-21 | 2010-09-23 | Arkray, Inc. | Measuring reagent and turbidimetric immunoassay and sample analysis tool using the same |
| US9182391B2 (en) | 2008-05-09 | 2015-11-10 | Arkray, Inc. | Method of producing insoluble carrier particles, insoluble carrier particles, measurement reagent, specimen analyzing tool, and immunoturbidimetric assay |
| WO2010013525A1 (ja) * | 2008-07-31 | 2010-02-04 | 日東紡績株式会社 | 複合体の測定方法およびそれに用いるキット |
| WO2011052380A1 (ja) * | 2009-10-28 | 2011-05-05 | 日東紡績株式会社 | ５．９ｋＤａペプチドの免疫学的測定方法 |
| JP5880029B2 (ja) * | 2011-12-27 | 2016-03-08 | 東ソー株式会社 | ２またはそれ以上の種類の形態で存在する物質の測定方法 |
| CN102628867B (zh) * | 2011-12-30 | 2016-03-23 | 北京九强生物技术股份有限公司 | 双抗体胶乳增强视黄醇结合蛋白检测试剂盒 |
| CN104662426B (zh) | 2012-09-27 | 2017-06-13 | 积水医疗株式会社 | 粒子凝集测定用胶乳粒子 |
| US9783671B2 (en) * | 2013-01-31 | 2017-10-10 | Fachhochschule Münster | Cross-linked plastic material with an intrinsic antimicrobial effect based on unsaturated polyesters |
| JP6051903B2 (ja) * | 2013-02-06 | 2016-12-27 | Jsr株式会社 | ラテックス凝集反応用凝集促進剤、標的物質の検出方法および標的物質の検出に用いるためのキット |
| JP6282819B2 (ja) * | 2013-08-12 | 2018-02-21 | オーソ・クリニカル・ダイアグノスティックス株式会社 | 検出対象を検出又は定量するためのキット、及び方法 |
| CN105158476A (zh) * | 2015-06-03 | 2015-12-16 | 南京闻智生物科技有限公司 | 一种全量程c反应蛋白胶乳增强免疫比浊检测试剂盒 |
| JP7278950B2 (ja) * | 2017-01-27 | 2023-05-22 | エフ． ホフマン－ラ ロシュ アーゲー | 相互作用アッセイにおけるシグナル強度を調節する方法 |
| CN113866412B (zh) * | 2021-09-07 | 2024-07-26 | 山东博科生物产业有限公司 | 一种灵敏的总前列腺特异性抗原检测试剂盒 |
| JP7355140B2 (ja) | 2022-02-28 | 2023-10-03 | 住友ベークライト株式会社 | セリンプロテアーゼの検出用または測定用試薬 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4210723A (en) * | 1976-07-23 | 1980-07-01 | The Dow Chemical Company | Method of coupling a protein to an epoxylated latex |
| US4401765A (en) * | 1981-09-01 | 1983-08-30 | E. I. Du Pont De Nemours And Company | Covalently bonded high refractive index particle reagents and their use in light scattering immunoassays |
| US5879881A (en) * | 1985-04-04 | 1999-03-09 | Hybritech, Incorporated | Solid phase system for use in ligand-receptor assays |
| JP2588174B2 (ja) | 1986-09-08 | 1997-03-05 | 三菱化学株式会社 | 抗原−抗体反応の測定法 |
| US5486479A (en) * | 1994-05-02 | 1996-01-23 | Mitsubishi Chemical Corporation | Buffer for immunoassay, kit including same and immunoassay method using said buffer |
| EP0789032A2 (en) | 1996-02-01 | 1997-08-13 | Bayer Corporation | Method for preparing a monoclonal antibody that provides an equimolar response to free and complexed analyte in a monoclonal/polyclonal sandwich immunoassay |
| JP3652029B2 (ja) | 1996-10-16 | 2005-05-25 | 積水化学工業株式会社 | 高感度免疫測定法 |
| CA2244326C (en) * | 1997-08-11 | 2006-03-28 | Shinichi Eda | Microparticle enhanced light scattering agglutination assay and microparticle reagents therefor |
| JP3920458B2 (ja) * | 1998-03-30 | 2007-05-30 | 第一化学薬品株式会社 | 免疫的測定法 |
| JP2001108681A (ja) * | 1999-10-07 | 2001-04-20 | Sysmex Corp | 免疫凝集測定用試薬及び測定方法 |
| WO2002018953A1 (en) * | 2000-08-29 | 2002-03-07 | Kyowa Medex Co.,Ltd | Highly reproducible agglutination immunoassay method and reagents |
| EP1385001A4 (en) * | 2001-03-30 | 2007-07-25 | Mitsubishi Kagaku Iatron Inc | REAGENT AND METHOD FOR THE IMMUNE ANALYSIS OF ELASTASE 1 AND METHOD FOR DETECTING PANCREASCONDUCTIVE DISEASE |
| JP4577747B2 (ja) * | 2001-06-05 | 2010-11-10 | 和光純薬工業株式会社 | 免疫学的測定法用凝集促進剤 |
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2003
- 2003-09-30 JP JP2003340028A patent/JP4241301B2/ja not_active Expired - Lifetime
-
2004
- 2004-06-15 US US10/867,912 patent/US7279339B2/en not_active Expired - Fee Related
-
2006
- 2006-03-30 US US11/394,463 patent/US20060172351A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012133482A1 (ja) | 2011-03-28 | 2012-10-04 | 積水メディカル株式会社 | Psaの測定方法及びその試薬 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005106609A (ja) | 2005-04-21 |
| US20060172351A1 (en) | 2006-08-03 |
| US20050069967A1 (en) | 2005-03-31 |
| US7279339B2 (en) | 2007-10-09 |
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