JP2005106609A5 - - Google Patents
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- Publication number
- JP2005106609A5 JP2005106609A5 JP2003340028A JP2003340028A JP2005106609A5 JP 2005106609 A5 JP2005106609 A5 JP 2005106609A5 JP 2003340028 A JP2003340028 A JP 2003340028A JP 2003340028 A JP2003340028 A JP 2003340028A JP 2005106609 A5 JP2005106609 A5 JP 2005106609A5
- Authority
- JP
- Japan
- Prior art keywords
- substance
- measured
- latex
- average particle
- reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000126 substance Substances 0.000 claims 17
- 239000004816 latex Substances 0.000 claims 13
- 229920000126 latex Polymers 0.000 claims 13
- 239000003153 chemical reaction reagent Substances 0.000 claims 7
- 239000002245 particle Substances 0.000 claims 7
- 230000002776 aggregation Effects 0.000 claims 6
- 238000004220 aggregation Methods 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 125000002947 alkylene group Chemical group 0.000 claims 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 4
- 239000000178 monomer Substances 0.000 claims 4
- 125000004430 oxygen atom Chemical group O* 0.000 claims 4
- 102000007066 Prostate-Specific Antigen Human genes 0.000 claims 3
- 108010072866 Prostate-Specific Antigen Proteins 0.000 claims 3
- 230000004520 agglutination Effects 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N guanidine group Chemical group NC(=N)N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 230000001900 immune effect Effects 0.000 claims 2
- 238000005259 measurement Methods 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 239000002683 reaction inhibitor Substances 0.000 claims 2
- 125000001424 substituent group Chemical group 0.000 claims 2
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 claims 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 claims 1
- 150000002357 guanidines Chemical class 0.000 claims 1
- 238000003018 immunoassay Methods 0.000 claims 1
- 238000010324 immunological assay Methods 0.000 claims 1
- 0 C*(C)(N(*)*)OP([O-])(O**C(C(*)=C)=O)=O Chemical compound C*(C)(N(*)*)OP([O-])(O**C(C(*)=C)=O)=O 0.000 description 2
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003340028A JP4241301B2 (ja) | 2003-09-30 | 2003-09-30 | 免疫学的測定用試薬 |
| US10/867,912 US7279339B2 (en) | 2003-09-30 | 2004-06-15 | Reagent for an immunoassay |
| US11/394,463 US20060172351A1 (en) | 2003-09-30 | 2006-03-30 | Reagent for an immunoassay |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003340028A JP4241301B2 (ja) | 2003-09-30 | 2003-09-30 | 免疫学的測定用試薬 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005106609A JP2005106609A (ja) | 2005-04-21 |
| JP2005106609A5 true JP2005106609A5 (enExample) | 2006-07-06 |
| JP4241301B2 JP4241301B2 (ja) | 2009-03-18 |
Family
ID=34373384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003340028A Expired - Lifetime JP4241301B2 (ja) | 2003-09-30 | 2003-09-30 | 免疫学的測定用試薬 |
Country Status (2)
| Country | Link |
|---|---|
| US (2) | US7279339B2 (enExample) |
| JP (1) | JP4241301B2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4755112B2 (ja) * | 2004-12-24 | 2011-08-24 | 積水メディカル株式会社 | 抗原を測定するための試薬及び抗原の測定方法 |
| GB2432211B (en) * | 2005-11-12 | 2009-04-22 | Platform Diagnostics Ltd | Agglutination based assay system |
| CA2629290C (en) | 2005-11-12 | 2014-05-06 | Carolyn Jennifer Ruddell | Agglutination assay |
| JP5170742B2 (ja) * | 2005-12-28 | 2013-03-27 | 積水メディカル株式会社 | 凝集測定用試薬及び凝集測定方法 |
| EP2006685A1 (en) * | 2006-03-31 | 2008-12-24 | Nissui Pharmaceutical Co., Ltd. | Immune agglutination reaction reagent kit and method of assaying antigen |
| JP4982107B2 (ja) * | 2006-04-28 | 2012-07-25 | アルフレッサファーマ株式会社 | 免疫学的微小粒子の凝集反応を用いる検体の測定方法および測定用キット |
| EP2146207A4 (en) * | 2007-11-21 | 2010-12-29 | Arkray Inc | MEASUREMENT REAGENT, ITS USE IN IMMUNO NEPHELOMETRY, AND ANALYSIS ANALYSIS INSTRUMENT |
| CN102007412A (zh) * | 2008-05-09 | 2011-04-06 | 爱科来株式会社 | 不溶性载体颗粒的制造方法、不溶性载体颗粒、测定试剂、待测物分析用具和免疫比浊法 |
| US8900882B2 (en) * | 2008-07-31 | 2014-12-02 | Nitto Boseki Co., Ltd. | Method of assaying complex and kit to be used therefor |
| EP2495564B1 (en) * | 2009-10-28 | 2015-12-16 | Nitto Boseki Co., Ltd | 5.9 kDa PEPTIDE IMMUNOASSAY METHOD |
| EP2698633B1 (en) * | 2011-03-28 | 2017-10-11 | Sekisui Medical Co., Ltd. | Psa assay method and reagent therefor |
| JP5880029B2 (ja) * | 2011-12-27 | 2016-03-08 | 東ソー株式会社 | ２またはそれ以上の種類の形態で存在する物質の測定方法 |
| CN102628867B (zh) * | 2011-12-30 | 2016-03-23 | 北京九强生物技术股份有限公司 | 双抗体胶乳增强视黄醇结合蛋白检测试剂盒 |
| WO2014051098A1 (ja) | 2012-09-27 | 2014-04-03 | 積水メディカル株式会社 | 粒子凝集測定用ラテックス粒子 |
| EP2951245B1 (de) * | 2013-01-31 | 2017-08-02 | Fachhochschule Münster | Vernetzter kunststoffwerkstoff mit intrinsisch antimikrobieller wirkung auf basis ungesättigter polyester |
| JP6051903B2 (ja) * | 2013-02-06 | 2016-12-27 | Jsr株式会社 | ラテックス凝集反応用凝集促進剤、標的物質の検出方法および標的物質の検出に用いるためのキット |
| JP6282819B2 (ja) * | 2013-08-12 | 2018-02-21 | オーソ・クリニカル・ダイアグノスティックス株式会社 | 検出対象を検出又は定量するためのキット、及び方法 |
| CN105158476A (zh) * | 2015-06-03 | 2015-12-16 | 南京闻智生物科技有限公司 | 一种全量程c反应蛋白胶乳增强免疫比浊检测试剂盒 |
| JP7278950B2 (ja) * | 2017-01-27 | 2023-05-22 | エフ． ホフマン－ラ ロシュ アーゲー | 相互作用アッセイにおけるシグナル強度を調節する方法 |
| CN113866412B (zh) * | 2021-09-07 | 2024-07-26 | 山东博科生物产业有限公司 | 一种灵敏的总前列腺特异性抗原检测试剂盒 |
| JP7355140B2 (ja) | 2022-02-28 | 2023-10-03 | 住友ベークライト株式会社 | セリンプロテアーゼの検出用または測定用試薬 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4210723A (en) * | 1976-07-23 | 1980-07-01 | The Dow Chemical Company | Method of coupling a protein to an epoxylated latex |
| US4401765A (en) * | 1981-09-01 | 1983-08-30 | E. I. Du Pont De Nemours And Company | Covalently bonded high refractive index particle reagents and their use in light scattering immunoassays |
| US5879881A (en) * | 1985-04-04 | 1999-03-09 | Hybritech, Incorporated | Solid phase system for use in ligand-receptor assays |
| JP2588174B2 (ja) | 1986-09-08 | 1997-03-05 | 三菱化学株式会社 | 抗原−抗体反応の測定法 |
| US5486479A (en) * | 1994-05-02 | 1996-01-23 | Mitsubishi Chemical Corporation | Buffer for immunoassay, kit including same and immunoassay method using said buffer |
| EP0789032A2 (en) | 1996-02-01 | 1997-08-13 | Bayer Corporation | Method for preparing a monoclonal antibody that provides an equimolar response to free and complexed analyte in a monoclonal/polyclonal sandwich immunoassay |
| JP3652029B2 (ja) | 1996-10-16 | 2005-05-25 | 積水化学工業株式会社 | 高感度免疫測定法 |
| CA2244326C (en) * | 1997-08-11 | 2006-03-28 | Shinichi Eda | Microparticle enhanced light scattering agglutination assay and microparticle reagents therefor |
| JP3920458B2 (ja) * | 1998-03-30 | 2007-05-30 | 第一化学薬品株式会社 | 免疫的測定法 |
| JP2001108681A (ja) * | 1999-10-07 | 2001-04-20 | Sysmex Corp | 免疫凝集測定用試薬及び測定方法 |
| JP4733335B2 (ja) * | 2000-08-29 | 2011-07-27 | 協和メデックス株式会社 | 再現性良好な凝集イムノアッセイ法及び試薬 |
| EP1385001A4 (en) * | 2001-03-30 | 2007-07-25 | Mitsubishi Kagaku Iatron Inc | REAGENT AND METHOD FOR THE IMMUNE ANALYSIS OF ELASTASE 1 AND METHOD FOR DETECTING PANCREASCONDUCTIVE DISEASE |
| JP4577747B2 (ja) * | 2001-06-05 | 2010-11-10 | 和光純薬工業株式会社 | 免疫学的測定法用凝集促進剤 |
-
2003
- 2003-09-30 JP JP2003340028A patent/JP4241301B2/ja not_active Expired - Lifetime
-
2004
- 2004-06-15 US US10/867,912 patent/US7279339B2/en not_active Expired - Fee Related
-
2006
- 2006-03-30 US US11/394,463 patent/US20060172351A1/en not_active Abandoned
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