JP4237267B2 - 磁気応答性試薬を使用する磁気補助結合アッセイ - Google Patents
磁気応答性試薬を使用する磁気補助結合アッセイ Download PDFInfo
- Publication number
- JP4237267B2 JP4237267B2 JP54956998A JP54956998A JP4237267B2 JP 4237267 B2 JP4237267 B2 JP 4237267B2 JP 54956998 A JP54956998 A JP 54956998A JP 54956998 A JP54956998 A JP 54956998A JP 4237267 B2 JP4237267 B2 JP 4237267B2
- Authority
- JP
- Japan
- Prior art keywords
- reagent
- magnetically responsive
- analyte
- solid phase
- complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/806—Electrical property or magnetic property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/832—Nanostructure having specified property, e.g. lattice-constant, thermal expansion coefficient
- Y10S977/838—Magnetic property of nanomaterial
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/84—Manufacture, treatment, or detection of nanostructure
- Y10S977/89—Deposition of materials, e.g. coating, cvd, or ald
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/92—Detection of biochemical
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/932—Specified use of nanostructure for electronic or optoelectronic application
- Y10S977/953—Detector using nanostructure
- Y10S977/96—Of magnetic property
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/857,440 | 1997-05-16 | ||
| US08/857,440 US5998224A (en) | 1997-05-16 | 1997-05-16 | Magnetically assisted binding assays utilizing a magnetically responsive reagent |
| PCT/US1998/009945 WO1998052043A1 (en) | 1997-05-16 | 1998-05-15 | Magnetically assisted binding assays utilizing a magnetically responsive reagent |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007148109A Division JP4324212B2 (ja) | 1997-05-16 | 2007-06-04 | 磁気応答性試薬を使用する磁気補助結合アッセイ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002504993A JP2002504993A (ja) | 2002-02-12 |
| JP2002504993A5 JP2002504993A5 (enExample) | 2005-12-08 |
| JP4237267B2 true JP4237267B2 (ja) | 2009-03-11 |
Family
ID=25326006
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP54956998A Expired - Lifetime JP4237267B2 (ja) | 1997-05-16 | 1998-05-15 | 磁気応答性試薬を使用する磁気補助結合アッセイ |
| JP2007148109A Expired - Fee Related JP4324212B2 (ja) | 1997-05-16 | 2007-06-04 | 磁気応答性試薬を使用する磁気補助結合アッセイ |
| JP2009107323A Expired - Lifetime JP4806457B2 (ja) | 1997-05-16 | 2009-04-27 | 磁気応答性試薬を使用する磁気補助結合アッセイ |
| JP2011155429A Pending JP2011257413A (ja) | 1997-05-16 | 2011-07-14 | 磁気応答性試薬を使用する磁気補助結合アッセイ |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007148109A Expired - Fee Related JP4324212B2 (ja) | 1997-05-16 | 2007-06-04 | 磁気応答性試薬を使用する磁気補助結合アッセイ |
| JP2009107323A Expired - Lifetime JP4806457B2 (ja) | 1997-05-16 | 2009-04-27 | 磁気応答性試薬を使用する磁気補助結合アッセイ |
| JP2011155429A Pending JP2011257413A (ja) | 1997-05-16 | 2011-07-14 | 磁気応答性試薬を使用する磁気補助結合アッセイ |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5998224A (enExample) |
| EP (2) | EP0981749B1 (enExample) |
| JP (4) | JP4237267B2 (enExample) |
| AT (1) | ATE412898T1 (enExample) |
| CA (1) | CA2290018C (enExample) |
| DE (1) | DE69840166D1 (enExample) |
| ES (2) | ES2378782T3 (enExample) |
| WO (1) | WO1998052043A1 (enExample) |
Families Citing this family (123)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19753851A1 (de) * | 1997-12-04 | 1999-06-10 | Roche Diagnostics Gmbh | Vorrichtung zum kapillaren Flüssigkeitstransport |
| AU3474100A (en) * | 1999-01-25 | 2000-08-07 | Minerva Biotechnologies Corporation | Rapid and sensitive detection of aberrant protein aggregation in neurodegenerative diseases |
| CA2370745A1 (en) * | 1999-02-17 | 2000-08-24 | Kilian Hennes | Method for representing biologically activated inductance-altering particles and device for carrying out the method |
| WO2001018235A2 (en) * | 1999-09-09 | 2001-03-15 | Eichrom Technologies, Inc. | Lateral flow device with metal oxide indicator and assay method employing same |
| US7537938B2 (en) | 2000-04-28 | 2009-05-26 | Monogram Biosciences, Inc. | Biomarker detection in circulating cells |
| US7015047B2 (en) * | 2001-01-26 | 2006-03-21 | Aviva Biosciences Corporation | Microdevices having a preferential axis of magnetization and uses thereof |
| US7811768B2 (en) * | 2001-01-26 | 2010-10-12 | Aviva Biosciences Corporation | Microdevice containing photorecognizable coding patterns and methods of using and producing the same |
| FR2826882B1 (fr) * | 2001-07-09 | 2003-09-12 | Bio Merieux | Procede de traitement de particules magnetiques et configurations d'aimants permettant la mise en oeuvre de ce procede |
| US7169577B2 (en) * | 2001-07-27 | 2007-01-30 | Surface Logix, Inc. | Cell isolation and screening device and method of using same |
| US7285412B2 (en) * | 2001-07-27 | 2007-10-23 | Surface Logix Inc. | Device for magnetic immobilization of cells |
| US7169578B2 (en) * | 2001-07-27 | 2007-01-30 | Surface Logix, Inc. | Cell isolation and screening device and method of using same |
| US20040086885A1 (en) * | 2002-02-22 | 2004-05-06 | Purdue Research Foundation | Magnetic nanomaterials and methods for detection of biological materials |
| US8697029B2 (en) * | 2002-04-18 | 2014-04-15 | The Regents Of The University Of Michigan | Modulated physical and chemical sensors |
| EP1532274A4 (en) * | 2002-06-28 | 2006-09-27 | Purdue Research Foundation | MAGNETIC NANOMATERIALS AND METHODS FOR DETECTING BIOLOGICAL MATERIALS |
| US7601491B2 (en) | 2003-02-06 | 2009-10-13 | Becton, Dickinson And Company | Pretreatment method for extraction of nucleic acid from biological samples and kits therefor |
| CN1280428C (zh) * | 2003-05-19 | 2006-10-18 | 清华大学 | 一种基于微小颗粒的生物芯片系统及其应用 |
| FR2855613B1 (fr) * | 2003-05-26 | 2005-08-19 | Biocytex | Procede de detection et de quantification multiplex d'analytes dans un echantillon a l'aide de microspheres |
| US7402398B2 (en) | 2003-07-17 | 2008-07-22 | Monogram Biosciences, Inc. | Measuring receptor homodimerization |
| AU2004267420A1 (en) | 2003-08-11 | 2005-03-03 | Monogram Biosciences, Inc. | Detecting and profiling molecular complexes |
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
| US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
| US20050282182A1 (en) * | 2003-12-30 | 2005-12-22 | Universal Bio Research Co., Ltd. | Reaction vessel and reaction apparatus comprising three-dimensional particle array |
| JP2005315677A (ja) * | 2004-04-28 | 2005-11-10 | Canon Inc | 検出装置および検出方法 |
| DE102004033811A1 (de) * | 2004-07-12 | 2006-02-02 | Salama, Abdulgabar, Prof. Dr. | Verfahren zum einfachen und schnellen Nachweis von Zellen und Biomolekülen mit Hilfe paramagnetischer Partikel |
| US20070045902A1 (en) | 2004-07-13 | 2007-03-01 | Brauker James H | Analyte sensor |
| US9414777B2 (en) | 2004-07-13 | 2016-08-16 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US20060024776A1 (en) * | 2004-08-02 | 2006-02-02 | Mcmillian Ray | Magnetic particle capture of whole intact organisms from clinical samples |
| WO2006047777A2 (en) | 2004-10-27 | 2006-05-04 | Cepheid | Closed-system multi-stage nucleic acid amplification reactions |
| US7939267B2 (en) * | 2004-11-04 | 2011-05-10 | Laboratory Corporation Of America Holdings | Detection of activation of endothelial cells as surrogate marker for angiogenesis |
| PL1859330T3 (pl) | 2005-01-28 | 2013-01-31 | Univ Duke | Urządzenia i sposoby manipulacji kropelkami na płytkach obwodów drukowanych |
| DE602006000724T2 (de) | 2005-02-05 | 2009-04-23 | Samsung Electronics Co., Ltd., Suwon | Sensorschalter und seine Verwendung in einem Nachweisverfahren |
| US7781228B2 (en) | 2005-04-07 | 2010-08-24 | Menon & Associates, Inc. | Magnetic resonance system and method to detect and confirm analytes |
| US7300631B2 (en) | 2005-05-02 | 2007-11-27 | Bioscale, Inc. | Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles |
| US7263874B2 (en) * | 2005-06-08 | 2007-09-04 | Bioscale, Inc. | Methods and apparatus for determining properties of a fluid |
| US20060281104A1 (en) * | 2005-06-13 | 2006-12-14 | Macevicz Stephen C | Leuco dye particles and uses thereof |
| US20070020699A1 (en) * | 2005-07-19 | 2007-01-25 | Idexx Laboratories, Inc. | Lateral flow assay and device using magnetic particles |
| US20070059782A1 (en) * | 2005-09-13 | 2007-03-15 | Graham Henry A | Magnetic particle tagged blood bank reagents and techniques |
| US9488665B2 (en) * | 2005-09-13 | 2016-11-08 | Chrome Red Technologies, Llc | Magnetic particle tagged reagents and techniques |
| US20070166730A1 (en) | 2006-01-19 | 2007-07-19 | Menon & Associates, Inc. | Magnetic resonance system and method to detect and confirm analytes |
| EP2000484B1 (en) * | 2006-03-27 | 2011-11-30 | Tokyo Institute of Technology | Process for producing polymer-coated ferromagnetic particle, and polymer-coated ferromagnetic particle |
| US8492168B2 (en) * | 2006-04-18 | 2013-07-23 | Advanced Liquid Logic Inc. | Droplet-based affinity assays |
| US20140193807A1 (en) | 2006-04-18 | 2014-07-10 | Advanced Liquid Logic, Inc. | Bead manipulation techniques |
| US9476856B2 (en) * | 2006-04-13 | 2016-10-25 | Advanced Liquid Logic, Inc. | Droplet-based affinity assays |
| US10078078B2 (en) | 2006-04-18 | 2018-09-18 | Advanced Liquid Logic, Inc. | Bead incubation and washing on a droplet actuator |
| US8637324B2 (en) | 2006-04-18 | 2014-01-28 | Advanced Liquid Logic, Inc. | Bead incubation and washing on a droplet actuator |
| US8809068B2 (en) | 2006-04-18 | 2014-08-19 | Advanced Liquid Logic, Inc. | Manipulation of beads in droplets and methods for manipulating droplets |
| US8389297B2 (en) * | 2006-04-18 | 2013-03-05 | Duke University | Droplet-based affinity assay device and system |
| US7901947B2 (en) | 2006-04-18 | 2011-03-08 | Advanced Liquid Logic, Inc. | Droplet-based particle sorting |
| US7439014B2 (en) | 2006-04-18 | 2008-10-21 | Advanced Liquid Logic, Inc. | Droplet-based surface modification and washing |
| US8900828B2 (en) | 2006-05-01 | 2014-12-02 | Cepheid | Methods and apparatus for sequential amplification reactions |
| US9675972B2 (en) | 2006-05-09 | 2017-06-13 | Advanced Liquid Logic, Inc. | Method of concentrating beads in a droplet |
| US8119352B2 (en) * | 2006-06-20 | 2012-02-21 | Cepheld | Multi-stage amplification reactions by control of sequence replication times |
| ES2649986T3 (es) * | 2006-07-24 | 2018-01-16 | Becton Dickinson And Company | Aparato y procedimiento para la concentración de partículas de ensayo |
| EP2111554B1 (en) | 2007-02-09 | 2013-05-08 | Advanced Liquid Logic, Inc. | Droplet actuator devices and methods employing magnetic beads |
| US9068977B2 (en) * | 2007-03-09 | 2015-06-30 | The Regents Of The University Of Michigan | Non-linear rotation rates of remotely driven particles and uses thereof |
| US8702938B2 (en) | 2007-09-04 | 2014-04-22 | Advanced Liquid Logic, Inc. | Droplet actuator with improved top substrate |
| EP2237955A4 (en) | 2007-12-23 | 2016-04-20 | Advanced Liquid Logic Inc | DROPLET FORMATION ACTUATOR CONFIGURATIONS, AND METHODS OF PERFORMING DROPLET FORMING OPERATIONS |
| US7927561B2 (en) * | 2008-01-10 | 2011-04-19 | Becton, Dickinson And Company | Rapid particle detection assay |
| EP2235516B1 (en) | 2008-01-17 | 2017-10-11 | The Regents of The University of California | Integrated magnetic field generation and detection platform |
| US8076162B2 (en) * | 2008-04-07 | 2011-12-13 | Life Bioscience, Inc. | Method of providing particles having biological-binding areas for biological applications |
| US8852952B2 (en) | 2008-05-03 | 2014-10-07 | Advanced Liquid Logic, Inc. | Method of loading a droplet actuator |
| US8926065B2 (en) | 2009-08-14 | 2015-01-06 | Advanced Liquid Logic, Inc. | Droplet actuator devices and methods |
| WO2011057197A2 (en) | 2009-11-06 | 2011-05-12 | Advanced Liquid Logic, Inc. | Integrated droplet actuator for gel electrophoresis and molecular analysis |
| EP2516669B1 (en) | 2009-12-21 | 2016-10-12 | Advanced Liquid Logic, Inc. | Enzyme assays on a droplet actuator |
| WO2011100358A2 (en) * | 2010-02-09 | 2011-08-18 | Fabrico Technology, Inc. | Systems and methods for detecting target analytes |
| WO2012019104A1 (en) | 2010-08-05 | 2012-02-09 | Abbott Point Of Care Inc. | Immunoassay method and device with magnetically susceptible bead capture |
| US9233370B2 (en) | 2010-08-05 | 2016-01-12 | Abbott Point Of Care Inc. | Magnetic immunosensor and method of use |
| US9329175B2 (en) | 2010-08-05 | 2016-05-03 | Abbott Point Of Care Inc. | Oscillating immunoassay method and device |
| US11402375B2 (en) | 2010-08-05 | 2022-08-02 | Abbott Point Of Care Inc. | Magnetic immunosensor with trench configuration and method of use |
| WO2012027747A2 (en) | 2010-08-27 | 2012-03-01 | The Regents Of The University Of Michigan | Asynchronous magnetic bead rotation sensing systems and methods |
| US20120077184A1 (en) * | 2010-09-28 | 2012-03-29 | Starkdx Incorporated | Electromagnetic multiplex assay biosensor |
| US9816993B2 (en) | 2011-04-11 | 2017-11-14 | The Regents Of The University Of Michigan | Magnetically induced microspinning for super-detection and super-characterization of biomarkers and live cells |
| CA2833897C (en) | 2011-05-09 | 2020-05-19 | Advanced Liquid Logic, Inc. | Microfluidic feedback using impedance detection |
| EP2729792A4 (en) | 2011-07-06 | 2015-03-18 | Advanced Liquid Logic Inc | STORING REAGENTS ON A DROPLET HANDLING ACTUATOR |
| US9513253B2 (en) | 2011-07-11 | 2016-12-06 | Advanced Liquid Logic, Inc. | Droplet actuators and techniques for droplet-based enzymatic assays |
| US9446404B2 (en) | 2011-07-25 | 2016-09-20 | Advanced Liquid Logic, Inc. | Droplet actuator apparatus and system |
| JP2013088164A (ja) * | 2011-10-14 | 2013-05-13 | Hitachi High-Technologies Corp | 自動分析装置 |
| WO2013078216A1 (en) | 2011-11-21 | 2013-05-30 | Advanced Liquid Logic Inc | Glucose-6-phosphate dehydrogenase assays |
| US9797817B2 (en) | 2012-05-03 | 2017-10-24 | The Regents Of The University Of Michigan | Multi-mode separation for target detection |
| EP2664914A1 (en) * | 2012-05-16 | 2013-11-20 | Koninklijke Philips N.V. | Magnetically assisted processing of a medium |
| CN104603595B (zh) | 2012-06-27 | 2017-08-08 | 先进流体逻辑公司 | 用于减少气泡形成的技术和液滴致动器设计 |
| EP2873976A4 (en) * | 2012-07-06 | 2016-01-27 | Toppan Printing Co Ltd | DETECTION SYSTEM FOR A TEST SUBSTANCE |
| JP6120518B2 (ja) * | 2012-10-10 | 2017-04-26 | 公益財団法人かずさDna研究所 | 簡易測定器具 |
| US20160299132A1 (en) | 2013-03-15 | 2016-10-13 | Ancera, Inc. | Systems and methods for bead-based assays in ferrofluids |
| US20160296945A1 (en) | 2013-03-15 | 2016-10-13 | Ancera, Inc. | Systems and methods for active particle separation |
| JP6420055B2 (ja) * | 2013-03-29 | 2018-11-07 | 積水メディカル株式会社 | イムノクロマト用着色粒子及びこれを用いた診断用イムノクロマト試薬 |
| US9983110B2 (en) | 2013-11-04 | 2018-05-29 | The Regents Of The University Of Michigan | Asynchronous magnetic bead rotation (AMBR) microviscometer for analysis of analytes |
| EP2883961B8 (en) * | 2013-12-12 | 2017-09-27 | Altratech Limited | A nucleic acid analysis method and apparatus |
| US10533170B2 (en) * | 2014-03-14 | 2020-01-14 | Shimadzu Corporation | Method for manipulating magnetic particles and device for manipulating magnetic particles |
| EP3920200A1 (en) | 2014-05-05 | 2021-12-08 | 3D Glass Solutions, Inc. | 2d and 3d inductors antenna and transformers fabricating photoactive substrates |
| JP6350654B2 (ja) * | 2014-05-23 | 2018-07-04 | 株式会社島津製作所 | 磁性体粒子の操作方法 |
| WO2016013115A1 (ja) * | 2014-07-25 | 2016-01-28 | 株式会社 リージャー | 希釈生体試料成分の分析方法 |
| KR101860543B1 (ko) * | 2015-01-09 | 2018-05-24 | 한양대학교 에리카산학협력단 | 성호르몬 검출용 시약 키트 및 이를 이용한 성호르몬 검출 방법 |
| US10656119B2 (en) * | 2015-06-26 | 2020-05-19 | Kawano Lab. Inc. | Dispersoid particle analyzing method and analyzing apparatus |
| WO2016210348A2 (en) | 2015-06-26 | 2016-12-29 | Ancera, Inc. | Background defocusing and clearing in ferrofluid-based capture assays |
| US20180178261A1 (en) * | 2015-09-22 | 2018-06-28 | Halliburton Energy Services, Inc | Optical Device Window Cleaning System |
| US10070533B2 (en) | 2015-09-30 | 2018-09-04 | 3D Glass Solutions, Inc. | Photo-definable glass with integrated electronics and ground plane |
| KR20180134868A (ko) | 2016-02-25 | 2018-12-19 | 3디 글래스 솔루션즈 인코포레이티드 | 3d 커패시터 및 커패시터 어레이 제작용 광활성 기재 |
| US12165809B2 (en) | 2016-02-25 | 2024-12-10 | 3D Glass Solutions, Inc. | 3D capacitor and capacitor array fabricating photoactive substrates |
| US11161773B2 (en) | 2016-04-08 | 2021-11-02 | 3D Glass Solutions, Inc. | Methods of fabricating photosensitive substrates suitable for optical coupler |
| KR101994370B1 (ko) * | 2016-08-24 | 2019-06-28 | 주식회사 제놉시 | 항체 및 자성 나노 입자가 결합된 전도성 고분자를 포함하는 혈중 암세포 검출 및 회수용 자성 나노 구조체 |
| US10845449B2 (en) | 2016-10-20 | 2020-11-24 | Quantum Diamond Technologies Inc. | Methods and apparatus for magnetic particle analysis using diamond magnetic imaging |
| US10590409B2 (en) * | 2016-12-06 | 2020-03-17 | Wisconsin Alumni Research Foundation | Method and device for disaggregation via heterogeneous particles |
| WO2018119367A1 (en) | 2016-12-23 | 2018-06-28 | Quantum Diamond Technologies Inc. | Methods and apparatus for magnetic multi-bead assays |
| WO2018200804A1 (en) | 2017-04-28 | 2018-11-01 | 3D Glass Solutions, Inc. | Rf circulator |
| JP6995891B2 (ja) | 2017-07-07 | 2022-01-17 | スリーディー グラス ソリューションズ,インク | パッケージ光活性ガラス基板内のrfシステムのための2d及び3dのrf集中素子デバイス |
| WO2019027917A1 (en) | 2017-07-31 | 2019-02-07 | Quantum Diamond Technologies, Inc | METHODS AND APPARATUS FOR SAMPLE MEASUREMENT |
| US10854946B2 (en) | 2017-12-15 | 2020-12-01 | 3D Glass Solutions, Inc. | Coupled transmission line resonate RF filter |
| WO2019136024A1 (en) | 2018-01-04 | 2019-07-11 | 3D Glass Solutions, Inc. | Impedance matching conductive structure for high efficiency rf circuits |
| JP7272348B2 (ja) * | 2018-03-20 | 2023-05-12 | 住友電気工業株式会社 | 微小粒子計測装置 |
| KR102626372B1 (ko) | 2018-04-10 | 2024-01-16 | 3디 글래스 솔루션즈 인코포레이티드 | Rf 집적형 전력 조절 커패시터 |
| JP6976409B2 (ja) | 2018-05-29 | 2021-12-08 | スリーディー グラス ソリューションズ, インク3D Glass Solutions, Inc | 低挿入損失rf伝送線路 |
| WO2019235270A1 (ja) * | 2018-06-08 | 2019-12-12 | 国立研究開発法人産業技術総合研究所 | 標的物質検出方法及び標的物質検出キット |
| CA3112608C (en) | 2018-09-17 | 2021-12-28 | 3D Glass Solutions, Inc. | High efficiency compact slotted antenna with a ground plane |
| KR102393450B1 (ko) | 2018-12-28 | 2022-05-04 | 3디 글래스 솔루션즈 인코포레이티드 | 광활성 유리 기판들에서 rf, 마이크로파, 및 mm 파 시스템들을 위한 이종 통합 |
| CA3107812C (en) | 2018-12-28 | 2023-06-27 | 3D Glass Solutions, Inc. | Annular capacitor rf, microwave and mm wave systems |
| US11962057B2 (en) | 2019-04-05 | 2024-04-16 | 3D Glass Solutions, Inc. | Glass based empty substrate integrated waveguide devices |
| JP7188825B2 (ja) | 2019-04-18 | 2022-12-13 | スリーディー グラス ソリューションズ,インク | 高効率ダイダイシング及びリリース |
| WO2020225900A1 (ja) * | 2019-05-09 | 2020-11-12 | 三菱電機株式会社 | 磁性摩耗粉量測定装置及び機械装置 |
| EP4121988A4 (en) | 2020-04-17 | 2023-08-30 | 3D Glass Solutions, Inc. | BROADBAND INDUCTOR |
| US20230194527A1 (en) * | 2020-05-12 | 2023-06-22 | National University Of Singapore | A Method For Virus and Biomarker Detection |
| RU200521U1 (ru) * | 2020-05-26 | 2020-10-28 | Алексей Николаевич Темников | Портативный сканер-дисплей магнитного поля |
| EP4252907A1 (en) * | 2022-03-30 | 2023-10-04 | Blink AG | A method for arranging microspheres in a non-aqueous liquid phase |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3985649A (en) * | 1974-11-25 | 1976-10-12 | Eddelman Roy T | Ferromagnetic separation process and material |
| US4070246A (en) * | 1976-04-09 | 1978-01-24 | Abbott Laboratories | Reactive matrices |
| GB8401368D0 (en) * | 1984-01-19 | 1984-02-22 | Amersham Int Plc | Assay method |
| US5076950A (en) * | 1985-12-20 | 1991-12-31 | Syntex (U.S.A.) Inc. | Magnetic composition for particle separation |
| JPH0614051B2 (ja) * | 1986-02-10 | 1994-02-23 | 株式会社ニッテク | 抗原―抗体不溶化担体の選別方法 |
| US4960691A (en) * | 1986-09-29 | 1990-10-02 | Abbott Laboratories | Chromatographic test strip for determining ligands or receptors |
| JPS63108264A (ja) * | 1986-10-25 | 1988-05-13 | Nippon Telegr & Teleph Corp <Ntt> | 磁気免疫測定方法および該方法を実施するために使用する検査試薬片 |
| US5236824A (en) * | 1988-04-26 | 1993-08-17 | Nippon Telegraph And Telephone Corporation | Laser magnetic immunoassay method and method by a magnetophoresis apparatus therefor |
| JP2599175B2 (ja) * | 1988-04-26 | 1997-04-09 | 日本電信電話株式会社 | レーザ磁気免疫測定方法及び測定装置並びにレーザ磁気免疫測定に用いる超常磁性体標識体及びその製造方法 |
| US5145784A (en) * | 1988-05-04 | 1992-09-08 | Cambridge Biotech Corporation | Double capture assay method employing a capillary flow device |
| US5108933A (en) * | 1988-09-16 | 1992-04-28 | Immunicon Corporation | Manipulation of colloids for facilitating magnetic separations |
| US5252459A (en) * | 1988-09-23 | 1993-10-12 | Abbott Laboratories | Indicator reagents, diagnostic assays and test kits employing organic polymer latex particles |
| CA1335181C (en) * | 1988-10-11 | 1995-04-11 | R. Alan Hardwick | System for selective cell separation from cell concentrate |
| TW221493B (enExample) * | 1990-07-10 | 1994-03-01 | Cardiovascular Diagnostics Inc | |
| JPH0552849A (ja) * | 1991-08-28 | 1993-03-02 | Terumo Corp | 検体の特異的検出および特異的分離方法 |
| DE69333569T2 (de) * | 1992-03-20 | 2005-08-04 | Abbott Laboratories, Abbott Park | Magnetisch assistierte bindungsassays unter verwendung von magnetisch markierten bindungspartnern. |
| WO1993019371A1 (en) * | 1992-03-20 | 1993-09-30 | Abbott Laboratories | Determination of binding affinity using magneticaly-labeled binding members |
| US5445970A (en) * | 1992-03-20 | 1995-08-29 | Abbott Laboratories | Magnetically assisted binding assays using magnetically labeled binding members |
| US5445971A (en) * | 1992-03-20 | 1995-08-29 | Abbott Laboratories | Magnetically assisted binding assays using magnetically labeled binding members |
| AU677780B2 (en) * | 1992-05-01 | 1997-05-08 | Trustees Of The University Of Pennsylvania, The | Microfabricated detection structures |
| US5358659A (en) * | 1992-07-09 | 1994-10-25 | Xerox Corporation | Magnetic materials with single-domain and multidomain crystallites and a method of preparation |
| US5322756A (en) * | 1992-07-09 | 1994-06-21 | Xerox Corporation | Magnetic fluids and method of preparation |
| AU6357394A (en) * | 1993-03-04 | 1994-09-26 | Sapidyne, Inc. | Assay flow apparatus and method |
| US5374531A (en) * | 1993-03-22 | 1994-12-20 | Zynaxis, Inc. | Immunoassay for determination of cells |
| FR2708348B1 (fr) * | 1993-07-28 | 1995-10-06 | Stago Diagnostica | Procédé de dosage d'une substance immunologique au moyen de particules de latex magnétiques et de particules non-magnétiques. |
| GB9409333D0 (en) * | 1994-05-10 | 1994-06-29 | Palmer Richard F | Analytical method and device for use therein |
| US5656429A (en) * | 1994-10-03 | 1997-08-12 | Adelman; Lonnie W. | Polynucleotide and protein analysis method using magnetizable moieties |
| FR2732116B1 (fr) * | 1995-03-21 | 1997-05-09 | Bio Merieux | Procede et dispositif pour la determination qualitative et/ou quantitative d'un analyte, notamment d'une bacterie, dans un echantillon, par voie magnetique |
| JPH08304399A (ja) * | 1995-04-28 | 1996-11-22 | Mitsubishi Chem Corp | 磁性体粒子の分離方法およびそれを用いた免疫分析方法 |
-
1997
- 1997-05-16 US US08/857,440 patent/US5998224A/en not_active Expired - Lifetime
-
1998
- 1998-05-15 CA CA2290018A patent/CA2290018C/en not_active Expired - Fee Related
- 1998-05-15 JP JP54956998A patent/JP4237267B2/ja not_active Expired - Lifetime
- 1998-05-15 WO PCT/US1998/009945 patent/WO1998052043A1/en not_active Ceased
- 1998-05-15 ES ES07118773T patent/ES2378782T3/es not_active Expired - Lifetime
- 1998-05-15 ES ES98921225T patent/ES2316163T3/es not_active Expired - Lifetime
- 1998-05-15 EP EP98921225A patent/EP0981749B1/en not_active Expired - Lifetime
- 1998-05-15 DE DE69840166T patent/DE69840166D1/de not_active Expired - Lifetime
- 1998-05-15 AT AT98921225T patent/ATE412898T1/de not_active IP Right Cessation
- 1998-05-15 EP EP07118773A patent/EP1881325B1/en not_active Expired - Lifetime
-
2007
- 2007-06-04 JP JP2007148109A patent/JP4324212B2/ja not_active Expired - Fee Related
-
2009
- 2009-04-27 JP JP2009107323A patent/JP4806457B2/ja not_active Expired - Lifetime
-
2011
- 2011-07-14 JP JP2011155429A patent/JP2011257413A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009204617A (ja) | 2009-09-10 |
| ES2378782T3 (es) | 2012-04-17 |
| JP2008003083A (ja) | 2008-01-10 |
| CA2290018C (en) | 2011-07-19 |
| CA2290018A1 (en) | 1998-11-19 |
| JP4806457B2 (ja) | 2011-11-02 |
| US5998224A (en) | 1999-12-07 |
| WO1998052043A1 (en) | 1998-11-19 |
| JP2002504993A (ja) | 2002-02-12 |
| EP1881325B1 (en) | 2012-01-11 |
| EP1881325A1 (en) | 2008-01-23 |
| JP4324212B2 (ja) | 2009-09-02 |
| DE69840166D1 (de) | 2008-12-11 |
| ATE412898T1 (de) | 2008-11-15 |
| JP2011257413A (ja) | 2011-12-22 |
| EP0981749A1 (en) | 2000-03-01 |
| EP0981749B1 (en) | 2008-10-29 |
| ES2316163T3 (es) | 2009-04-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4237267B2 (ja) | 磁気応答性試薬を使用する磁気補助結合アッセイ | |
| US6294342B1 (en) | Magnetically assisted binding assays utilizing a magnetically responsive reagent | |
| US5445970A (en) | Magnetically assisted binding assays using magnetically labeled binding members | |
| US5445971A (en) | Magnetically assisted binding assays using magnetically labeled binding members | |
| CA2129042C (en) | Magnetically assisted binding assays using magnetically-labeled binding members | |
| Richardson et al. | The use of coated paramagnetic particles as a physical label in a magneto-immunoassay | |
| US5374531A (en) | Immunoassay for determination of cells | |
| EP0631668B1 (en) | Determination of binding affinity using magnetically-labeled binding members | |
| US20020123079A1 (en) | Process for detecting or quantifying a biological rreaction using superparamagnetic label | |
| US20030124745A1 (en) | Process for detecting or quantifying a biological reaction using superparamagnetic label | |
| JP4801447B2 (ja) | 磁気センサを用いた測定装置及び測定方法 | |
| JP2005043049A (ja) | 超常磁性標識を用いて生物学的反応を検出または定量する方法 | |
| JPS63131064A (ja) | 蛋白質およびウイルスの検出法 | |
| JPH1130616A (ja) | 高感度免疫学的測定方法および測定キット |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20050511 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20050511 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20061205 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20070226 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20070416 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20070604 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20071218 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20080411 |
|
| A911 | Transfer to examiner for re-examination before appeal (zenchi) |
Free format text: JAPANESE INTERMEDIATE CODE: A911 Effective date: 20080626 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20080922 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20081028 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20081202 |
|
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20081218 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20111226 Year of fee payment: 3 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20111226 Year of fee payment: 3 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20121226 Year of fee payment: 4 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20121226 Year of fee payment: 4 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20131226 Year of fee payment: 5 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| EXPY | Cancellation because of completion of term |