JP4189048B2 - 複素環化合物 - Google Patents
複素環化合物 Download PDFInfo
- Publication number
- JP4189048B2 JP4189048B2 JP36788797A JP36788797A JP4189048B2 JP 4189048 B2 JP4189048 B2 JP 4189048B2 JP 36788797 A JP36788797 A JP 36788797A JP 36788797 A JP36788797 A JP 36788797A JP 4189048 B2 JP4189048 B2 JP 4189048B2
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- JP
- Japan
- Prior art keywords
- group
- carbon atoms
- substituted
- alkyl
- same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 0 **c(nc1[n]2Cc3ccccc3)nc(N)c1nc2O Chemical compound **c(nc1[n]2Cc3ccccc3)nc(N)c1nc2O 0.000 description 3
- BQGDDAYSNFLDLH-UHFFFAOYSA-N CC(C)CSc1nc(N)c2nc[n](Cc3ccccc3)c2n1 Chemical compound CC(C)CSc1nc(N)c2nc[n](Cc3ccccc3)c2n1 BQGDDAYSNFLDLH-UHFFFAOYSA-N 0.000 description 1
- CTFPXLSBZGGGJG-UHFFFAOYSA-N CCCSc(nc1[n]2Cc3ccccc3)nc(N)c1nc2Br Chemical compound CCCSc(nc1[n]2Cc3ccccc3)nc(N)c1nc2Br CTFPXLSBZGGGJG-UHFFFAOYSA-N 0.000 description 1
- VGSBMDOWAWHTIU-UHFFFAOYSA-N CCSc(nc1N)nc([n]2Cc3ccccc3)c1nc2O Chemical compound CCSc(nc1N)nc([n]2Cc3ccccc3)c1nc2O VGSBMDOWAWHTIU-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP36788797A JP4189048B2 (ja) | 1997-12-26 | 1997-12-26 | 複素環化合物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP36788797A JP4189048B2 (ja) | 1997-12-26 | 1997-12-26 | 複素環化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPH11193282A JPH11193282A (ja) | 1999-07-21 |
| JPH11193282A5 JPH11193282A5 (https=) | 2005-09-02 |
| JP4189048B2 true JP4189048B2 (ja) | 2008-12-03 |
Family
ID=18490454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP36788797A Expired - Fee Related JP4189048B2 (ja) | 1997-12-26 | 1997-12-26 | 複素環化合物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4189048B2 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7157465B2 (en) | 2001-04-17 | 2007-01-02 | Dainippon Simitomo Pharma Co., Ltd. | Adenine derivatives |
| MXPA05003193A (es) * | 2002-09-27 | 2005-06-08 | Sumitomo Pharma | Compuesto de adenina novedoso y uso del mismo. |
| JP2007504232A (ja) * | 2003-09-05 | 2007-03-01 | アナディス ファーマシューティカルズ インク | C型肝炎ウイルス感染治療用のtlr7リガンド及びそのプロドラッグの投与 |
| US8012964B2 (en) | 2004-03-26 | 2011-09-06 | Dainippon Sumitomo Pharma Co., Ltd. | 9-substituted 8-oxoadenine compound |
| CN101304748A (zh) * | 2005-08-22 | 2008-11-12 | 加利福尼亚大学董事会 | Tlr激动剂 |
| JP2009528989A (ja) | 2006-02-17 | 2009-08-13 | ファイザー・リミテッド | Tlr7変調剤としての3−デアザプリン誘導体 |
| US8138172B2 (en) | 2006-07-05 | 2012-03-20 | Astrazeneca Ab | 8-oxoadenine derivatives acting as modulators of TLR7 |
| TW200831105A (en) | 2006-12-14 | 2008-08-01 | Astrazeneca Ab | Novel compounds |
| CN101790380B (zh) | 2007-02-07 | 2013-07-10 | 加利福尼亚大学董事会 | 合成tlr激动剂的缀合物及其应用 |
| ES2457316T3 (es) | 2007-03-19 | 2014-04-25 | Astrazeneca Ab | Compuestos 8-oxo-adenina 9 sustituidos como moduladores del receptor similares a toll (TLR7) |
| ES2373616T3 (es) | 2007-03-19 | 2012-02-07 | Astrazeneca Ab | Compuestos de 8-oxo-adenina 9 sustituidos como moduladores del receptor de tipo toll (tlr7). |
| JPWO2008114819A1 (ja) | 2007-03-20 | 2010-07-08 | 大日本住友製薬株式会社 | 新規アデニン化合物 |
| AR065784A1 (es) * | 2007-03-20 | 2009-07-01 | Dainippon Sumitomo Pharma Co | Derivados de 8-oxo adenina,medicamentos que los contienen y usos como agentes terapeuticos para enfermedades alergicas, antivirales o antibacterianas. |
| HRP20120895T1 (hr) | 2007-05-08 | 2012-11-30 | Astrazeneca Ab | Imidazokinolini sa imuno-modulacijskim svojstvima |
| PE20091236A1 (es) | 2007-11-22 | 2009-09-16 | Astrazeneca Ab | Derivados de pirimidina como immunomoduladores de tlr7 |
| PE20091156A1 (es) | 2007-12-17 | 2009-09-03 | Astrazeneca Ab | Sales de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo |
| WO2009091032A1 (ja) | 2008-01-17 | 2009-07-23 | Dainippon Sumitomo Pharma Co., Ltd. | アデニン化合物の製造方法 |
| WO2010088924A1 (en) | 2009-02-06 | 2010-08-12 | Telormedix Sa | Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration |
| GB0908772D0 (en) | 2009-05-21 | 2009-07-01 | Astrazeneca Ab | New salts 756 |
| AU2010250923A1 (en) | 2009-05-21 | 2011-11-17 | Astrazeneca Ab | Novel pyrimidine derivatives and their use in the treatment of cancer and further diseases |
| JP5694345B2 (ja) | 2009-10-22 | 2015-04-01 | ギリアード サイエンシーズ, インコーポレイテッド | Toll様受容体の調節因子 |
| AU2011247358B2 (en) | 2010-04-30 | 2014-10-30 | Urogen Pharma Ltd. | Phospholipid drug analogs |
| US9050319B2 (en) | 2010-04-30 | 2015-06-09 | Telormedix, Sa | Phospholipid drug analogs |
| CN103370317B (zh) | 2010-12-16 | 2015-10-07 | 阿斯利康(瑞典)有限公司 | 可用于治疗的咪唑并[4,5-c]喹啉-1-基衍生物 |
| ES2627433T3 (es) | 2010-12-17 | 2017-07-28 | Sumitomo Dainippon Pharma Co., Ltd. | Derivados de purina |
| JP6184423B2 (ja) | 2012-05-18 | 2017-08-23 | 大日本住友製薬株式会社 | カルボン酸化合物 |
| PL3294740T3 (pl) | 2015-05-08 | 2020-03-31 | F. Hoffmann-La Roche Ag | Nowe sulfonoimidoilopurynony i pochodne do leczenia i profilaktyki infekcji wirusowych |
| US11697851B2 (en) | 2016-05-24 | 2023-07-11 | The Regents Of The University Of California | Early ovarian cancer detection diagnostic test based on mRNA isoforms |
| PL3504210T3 (pl) * | 2016-08-29 | 2021-07-05 | F. Hoffmann-La Roche Ag | 7-podstawione związki sulfonimidoilopurynonowe do leczenia i profilaktyki zakażeń wirusowych |
| EP3512556B1 (en) | 2016-09-13 | 2021-08-18 | F. Hoffmann-La Roche AG | Combined treatment with a tlr7 agonist and an hbv capsid assembly inhibitor |
| JP7328977B2 (ja) * | 2018-02-12 | 2023-08-17 | エフ. ホフマン-ラ ロシュ アーゲー | ウイルス感染の処置および予防のための新規のスルホン化合物および誘導体 |
| JP7089596B2 (ja) * | 2018-02-28 | 2022-06-22 | エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト | 肝がんの治療及び予防のための7位置換スルホンイミドイルプリノン化合物及び誘導体 |
-
1997
- 1997-12-26 JP JP36788797A patent/JP4189048B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11193282A (ja) | 1999-07-21 |
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