JP4137053B2 - 新規形態のｎ−（トランス−４−イソプロピルシクロヘキシルカルボニル）−ｄ−フェニルアラニン - Google Patents

新規形態のｎ−（トランス−４−イソプロピルシクロヘキシルカルボニル）−ｄ−フェニルアラニン Download PDF

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JP4137053B2
JP4137053B2 JP2004501362A JP2004501362A JP4137053B2 JP 4137053 B2 JP4137053 B2 JP 4137053B2 JP 2004501362 A JP2004501362 A JP 2004501362A JP 2004501362 A JP2004501362 A JP 2004501362A JP 4137053 B2 JP4137053 B2 JP 4137053B2
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Prior art keywords
trans
isopropylcyclohexylcarbonyl
phenylalanine
methyl ester
phenylalanine methyl
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Expired - Fee Related
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JP2004501362A
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English (en)
Japanese (ja)
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JP2005523933A5 (enExample
JP2005523933A (ja
Inventor
ラジャマヘンドラ、シャンムグハサミー
アスワサナラヤナッパ、チャンドラシェカー
プシアパラムピル、トム・トーマス
スリドハラン、マドハバン
ガネシュ、サムバシバム
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Biocon Ltd
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Biocon Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2004501362A 2002-04-29 2002-04-29 新規形態のｎ−（トランス−４−イソプロピルシクロヘキシルカルボニル）−ｄ−フェニルアラニン Expired - Fee Related JP4137053B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2002/000114 WO2003093222A1 (en) 2002-04-29 2002-04-29 Novel form of n-(trans-4-isopropylcyclohexylcarbonyl)-d-phenylalanine

Publications (3)

Publication Number Publication Date
JP2005523933A JP2005523933A (ja) 2005-08-11
JP2005523933A5 JP2005523933A5 (enExample) 2008-05-22
JP4137053B2 true JP4137053B2 (ja) 2008-08-20

Family

ID=29287383

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004501362A Expired - Fee Related JP4137053B2 (ja) 2002-04-29 2002-04-29 新規形態のｎ−（トランス−４−イソプロピルシクロヘキシルカルボニル）−ｄ−フェニルアラニン

Country Status (13)

Country Link
US (1) US7314955B2 (enExample)
EP (1) EP1499586A4 (enExample)
JP (1) JP4137053B2 (enExample)
KR (1) KR20040111490A (enExample)
AU (1) AU2002304281A1 (enExample)
CA (1) CA2481322A1 (enExample)
CZ (1) CZ2004997A3 (enExample)
HR (1) HRP20040920A2 (enExample)
HU (1) HUP0500259A2 (enExample)
IL (1) IL164327A0 (enExample)
MX (1) MXNL04000084A (enExample)
SK (1) SK287644B6 (enExample)
WO (1) WO2003093222A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ2004997A3 (cs) 2002-04-29 2005-01-12 Biocon Limited Nová forma N-(trans-4-isopropylcyklohexylkarbonyl)-D-fenylalaninu
US6861553B2 (en) 2002-07-03 2005-03-01 Teva Pharmaceuticals Industries Ltd. Process for preparing nateglinide and intermediates thereof
US7148376B2 (en) 2002-07-18 2006-12-12 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7358390B2 (en) 2002-07-18 2008-04-15 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7420084B2 (en) 2002-07-18 2008-09-02 Teva Pharmaceutical Industries Ltd. Polymorphic forms of nateglinide
US7534913B2 (en) 2002-07-18 2009-05-19 Teva Pharmaceutica Industries Ltd. Crystalline form of nateglinide
WO2004020396A1 (en) * 2002-08-28 2004-03-11 Dr. Reddy's Laboratories Limited Crystalline form of nateglinide and process for preparation thereof
WO2004074330A1 (ja) * 2003-02-18 2004-09-02 Konishi Co., Ltd. 硬化性樹脂、その製造方法及び硬化性樹脂組成物
HU227073B1 (hu) * 2003-07-10 2010-06-28 Richter Gedeon Nyrt Eljárás királisan tiszta N-(transz-4-izopropil-ciklohexilkarbonil)-D-fenil-alanin (nateglinid) és kristálymódosulatainak elõállítására, valamint a G-kristálymódosulata
US20070231393A1 (en) * 2004-05-19 2007-10-04 University Of South Carolina System and Device for Magnetic Drug Targeting with Magnetic Drug Carrier Particles
GB0413084D0 (en) * 2004-06-11 2004-07-14 Cipla Ltd Process
US20100004334A1 (en) * 2008-07-01 2010-01-07 Mead Johnson Nutrition Company Nutritional Compositions Containing Punicalagins
US11390830B2 (en) 2018-10-05 2022-07-19 The Chemours Company Fc, Llc Compositions comprising 1,2-dichloro-1,2-difluoroethylene for use in cleaning and solvent applications

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6354321A (ja) * 1985-03-27 1988-03-08 Ajinomoto Co Inc 血糖降下剤
US4814684A (en) * 1987-09-30 1989-03-21 Trw Inc. Apparatus for extending the Vout/Vin ratio of a DC-to-DC converter
EP0526171B1 (en) * 1991-07-30 1997-03-05 Ajinomoto Co., Inc. Crystals of N-(trans-4-isopropylcyclohexylcarbonyl)-D-phenylalanine and methods for preparing them
US5463116A (en) * 1991-07-30 1995-10-31 Ajinomoto Co., Inc. Crystals of N- (trans-4-isopropylcyclohexlycarbonyl)-D-phenylalanine and methods for preparing them
CZ2004997A3 (cs) 2002-04-29 2005-01-12 Biocon Limited Nová forma N-(trans-4-isopropylcyklohexylkarbonyl)-D-fenylalaninu

Also Published As

Publication number Publication date
SK50052004A3 (sk) 2005-03-04
WO2003093222A1 (en) 2003-11-13
EP1499586A1 (en) 2005-01-26
KR20040111490A (ko) 2004-12-31
US20050165108A1 (en) 2005-07-28
HUP0500259A2 (hu) 2005-06-28
IL164327A0 (en) 2005-12-18
MXNL04000084A (es) 2006-02-28
EP1499586A4 (en) 2006-01-18
JP2005523933A (ja) 2005-08-11
HRP20040920A2 (en) 2005-02-28
SK287644B6 (sk) 2011-05-06
CZ2004997A3 (cs) 2005-01-12
AU2002304281A1 (en) 2003-11-17
CA2481322A1 (en) 2003-11-13
US7314955B2 (en) 2008-01-01

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