JP4056883B2 - ヘテロ環式インデン類似体の調製方法 - Google Patents
ヘテロ環式インデン類似体の調製方法 Download PDFInfo
- Publication number
- JP4056883B2 JP4056883B2 JP2002559391A JP2002559391A JP4056883B2 JP 4056883 B2 JP4056883 B2 JP 4056883B2 JP 2002559391 A JP2002559391 A JP 2002559391A JP 2002559391 A JP2002559391 A JP 2002559391A JP 4056883 B2 JP4056883 B2 JP 4056883B2
- Authority
- JP
- Japan
- Prior art keywords
- formula
- benzenesulfonyl
- carbazol
- ethyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 *C(OC(C=C)C1=CC(*)=C(*)*1)=O Chemical compound *C(OC(C=C)C1=CC(*)=C(*)*1)=O 0.000 description 7
- PKRHOMRMSQCMSJ-XWFWGDPBSA-N CC(C)(C=CC=C1)/C1=C\C=C(/Cc1c(cccc2)c2ccc1P(c1ccccc1)c1ccccc1)\OC Chemical compound CC(C)(C=CC=C1)/C1=C\C=C(/Cc1c(cccc2)c2ccc1P(c1ccccc1)c1ccccc1)\OC PKRHOMRMSQCMSJ-XWFWGDPBSA-N 0.000 description 1
- GNNXDVFUGWRNJW-UHFFFAOYSA-N CC1(C)OC(CP(c2ccccc22)=C3C2=CC=C[CH]3)C(CP(C2C=CC=CC22)c3c2cccc3)O1 Chemical compound CC1(C)OC(CP(c2ccccc22)=C3C2=CC=C[CH]3)C(CP(C2C=CC=CC22)c3c2cccc3)O1 GNNXDVFUGWRNJW-UHFFFAOYSA-N 0.000 description 1
- FFZGDNBZNMTOCK-UHFFFAOYSA-N COc1ccccc1OCCN(CC(COc1c(c2ccccc2[nH]2)c2ccc1)O)Cc1ccccc1 Chemical compound COc1ccccc1OCCN(CC(COc1c(c2ccccc2[nH]2)c2ccc1)O)Cc1ccccc1 FFZGDNBZNMTOCK-UHFFFAOYSA-N 0.000 description 1
- OGHNVEJMJSYVRP-UHFFFAOYSA-N COc1ccccc1OCCNCC(COc1c(c2ccccc2[nH]2)c2ccc1)O Chemical compound COc1ccccc1OCCNCC(COc1c(c2ccccc2[nH]2)c2ccc1)O OGHNVEJMJSYVRP-UHFFFAOYSA-N 0.000 description 1
- QPROSHQDBZQCPJ-IGIGNMNNSA-N CP(c1ccccc1)c(cccc1)c1Oc1ccccc1[C@@H](C1)C1(C1C=C1)c1ccccc1 Chemical compound CP(c1ccccc1)c(cccc1)c1Oc1ccccc1[C@@H](C1)C1(C1C=C1)c1ccccc1 QPROSHQDBZQCPJ-IGIGNMNNSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01101584 | 2001-01-25 | ||
| PCT/EP2002/000583 WO2002059089A2 (en) | 2001-01-25 | 2002-01-22 | Process for the preparation of heterocyclic indene analogs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004519465A JP2004519465A (ja) | 2004-07-02 |
| JP2004519465A5 JP2004519465A5 (https=) | 2005-05-26 |
| JP4056883B2 true JP4056883B2 (ja) | 2008-03-05 |
Family
ID=8176288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002559391A Expired - Fee Related JP4056883B2 (ja) | 2001-01-25 | 2002-01-22 | ヘテロ環式インデン類似体の調製方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6777559B2 (https=) |
| EP (1) | EP1355880A2 (https=) |
| JP (1) | JP4056883B2 (https=) |
| KR (1) | KR100559019B1 (https=) |
| CN (1) | CN1266131C (https=) |
| CA (1) | CA2434408C (https=) |
| JO (1) | JO2433B1 (https=) |
| MX (1) | MXPA03006606A (https=) |
| WO (1) | WO2002059089A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004501191A (ja) * | 2000-06-28 | 2004-01-15 | テバ ファーマシューティカル インダストリーズ リミティド | カルベジロール |
| MXPA04006909A (es) | 2002-01-15 | 2005-04-19 | Teva Pharma | Solidos cristalinos de carvedilol y procesos para su preparacion. |
| US20070191456A1 (en) * | 2004-04-22 | 2007-08-16 | Tarur Venkatasubramanian R | Novel process for the preparation of 1-(9h-carbazol-4-yloxy)-3-[[2-(-methoxyphenoxy)-ethyl] amino]-propan-2-ol |
| GB0411273D0 (en) * | 2004-05-20 | 2004-06-23 | Cipla Ltd | Process and product |
| US20070043099A1 (en) * | 2005-06-09 | 2007-02-22 | Igor Lifshitz | Crystalline forms of carvedilol and processes for their preparation |
| WO2008002683A2 (en) * | 2006-06-28 | 2008-01-03 | Teva Pharmaceutical Industries Ltd. | Polymorphous forms of carvedilol phosphate |
| WO2008038301A1 (en) * | 2006-09-26 | 2008-04-03 | Morepen Laboratories Limited | A process for the preparation of carvedilol |
| US20080207726A1 (en) * | 2007-02-26 | 2008-08-28 | Santiago Ini | Process for the purification of carvedilol or its salts thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2258431T3 (es) | 1999-08-02 | 2006-09-01 | F. Hoffmann-La Roche Ag | Proceso para la preparacion de derivados de benzotiofeno. |
-
2002
- 2002-01-22 MX MXPA03006606A patent/MXPA03006606A/es not_active Application Discontinuation
- 2002-01-22 EP EP02716673A patent/EP1355880A2/en not_active Withdrawn
- 2002-01-22 WO PCT/EP2002/000583 patent/WO2002059089A2/en not_active Ceased
- 2002-01-22 CN CNB028041208A patent/CN1266131C/zh not_active Expired - Fee Related
- 2002-01-22 KR KR1020037009790A patent/KR100559019B1/ko not_active Expired - Fee Related
- 2002-01-22 JO JO20028A patent/JO2433B1/en active
- 2002-01-22 CA CA002434408A patent/CA2434408C/en not_active Expired - Fee Related
- 2002-01-22 US US10/054,462 patent/US6777559B2/en not_active Expired - Fee Related
- 2002-01-22 JP JP2002559391A patent/JP4056883B2/ja not_active Expired - Fee Related
-
2004
- 2004-01-22 US US10/763,296 patent/US7169935B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004519465A (ja) | 2004-07-02 |
| EP1355880A2 (en) | 2003-10-29 |
| CA2434408A1 (en) | 2002-08-01 |
| WO2002059089A3 (en) | 2002-10-31 |
| JO2433B1 (en) | 2008-04-17 |
| MXPA03006606A (es) | 2003-09-22 |
| US20040127723A1 (en) | 2004-07-01 |
| WO2002059089A2 (en) | 2002-08-01 |
| KR100559019B1 (ko) | 2006-03-10 |
| KR20030077007A (ko) | 2003-09-29 |
| CN1487922A (zh) | 2004-04-07 |
| US7169935B2 (en) | 2007-01-30 |
| US20020099223A1 (en) | 2002-07-25 |
| CN1266131C (zh) | 2006-07-26 |
| CA2434408C (en) | 2009-10-20 |
| US6777559B2 (en) | 2004-08-17 |
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