JP3320411B2 - Ｃ型肝炎ウイルスプロテアーゼ - Google Patents
Ｃ型肝炎ウイルスプロテアーゼInfo
- Publication number
- JP3320411B2 JP3320411B2 JP50763191A JP50763191A JP3320411B2 JP 3320411 B2 JP3320411 B2 JP 3320411B2 JP 50763191 A JP50763191 A JP 50763191A JP 50763191 A JP50763191 A JP 50763191A JP 3320411 B2 JP3320411 B2 JP 3320411B2
- Authority
- JP
- Japan
- Prior art keywords
- protease
- hcv protease
- hcv
- activity
- analog
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
- C12N9/506—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses derived from RNA viruses
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50543390A | 1990-04-04 | 1990-04-04 | |
| US505,433 | 1990-04-04 | ||
| PCT/US1991/002210 WO1991015575A1 (fr) | 1990-04-04 | 1991-04-04 | Protease du virus de l'hepatite c |
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|---|---|---|---|
| JP2001176369A Division JP3507045B2 (ja) | 1990-04-04 | 2001-06-11 | Ｃ型肝炎ウイルスプロテアーゼ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH05507612A JPH05507612A (ja) | 1993-11-04 |
| JP3320411B2 true JP3320411B2 (ja) | 2002-09-03 |
Family
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Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50763191A Expired - Lifetime JP3320411B2 (ja) | 1990-04-04 | 1991-04-04 | Ｃ型肝炎ウイルスプロテアーゼ |
| JP2001176369A Expired - Lifetime JP3507045B2 (ja) | 1990-04-04 | 2001-06-11 | Ｃ型肝炎ウイルスプロテアーゼ |
| JP2003373722A Withdrawn JP2004073212A (ja) | 1990-04-04 | 2003-10-31 | Ｃ型肝炎ウイルスプロテアーゼ |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001176369A Expired - Lifetime JP3507045B2 (ja) | 1990-04-04 | 2001-06-11 | Ｃ型肝炎ウイルスプロテアーゼ |
| JP2003373722A Withdrawn JP2004073212A (ja) | 1990-04-04 | 2003-10-31 | Ｃ型肝炎ウイルスプロテアーゼ |
Country Status (12)
| Country | Link |
|---|---|
| US (7) | US5371017A (fr) |
| EP (2) | EP0527788B1 (fr) |
| JP (3) | JP3320411B2 (fr) |
| AT (2) | ATE433460T1 (fr) |
| AU (1) | AU7675491A (fr) |
| CA (1) | CA2079105C (fr) |
| DE (2) | DE69133617D1 (fr) |
| DK (1) | DK0527788T3 (fr) |
| ES (2) | ES2324597T3 (fr) |
| IE (1) | IE911129A1 (fr) |
| PL (1) | PL169273B1 (fr) |
| WO (1) | WO1991015575A1 (fr) |
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|---|
| Ｎｕｃｌｅｉｃ Ａｃｉｄｓ Ｒｅｓｅａｒｃｈ，１９８９年，Ｖｏｌ．１７，Ｎｏ．２４，ｐ．１０３６７−１０３７２ |
| Ｐｒｏｃ．Ｎａｔｌ．Ａｃａｄ．Ｓｃｉ．ＵＳＡ，１９９０年 ３月，Ｖｏｌ．８７，ｐ．２０５７−２０６１ |
| ＰＲＯＴＥＩＮＳ：Ｓｔｒｕｃｔｕｒｅ，Ｆｕｎｃｔｉｏｎ，ａｎｄ Ｇｅｎｅｔｉｃｓ，１９８９年，Ｖｏｌ．６，ｐ．３２４−３３７ |
Also Published As
| Publication number | Publication date |
|---|---|
| DE69133402D1 (de) | 2004-08-12 |
| US5885799A (en) | 1999-03-23 |
| EP1304335B1 (fr) | 2009-06-10 |
| DK0527788T3 (da) | 2004-09-06 |
| ATE433460T1 (de) | 2009-06-15 |
| EP1304335A3 (fr) | 2004-04-07 |
| WO1991015575A1 (fr) | 1991-10-17 |
| EP0527788A1 (fr) | 1993-02-24 |
| ATE270326T1 (de) | 2004-07-15 |
| US5597691C1 (en) | 2001-12-11 |
| CA2079105C (fr) | 2000-06-13 |
| US5371017A (en) | 1994-12-06 |
| IE20060594A1 (en) | 2009-05-27 |
| JP3507045B2 (ja) | 2004-03-15 |
| EP0527788B1 (fr) | 2004-06-30 |
| ES2324597T3 (es) | 2009-08-11 |
| US5597691A (en) | 1997-01-28 |
| US5712145A (en) | 1998-01-27 |
| IE911129A1 (en) | 1991-10-09 |
| DE69133617D1 (de) | 2009-07-23 |
| EP1304335A2 (fr) | 2003-04-23 |
| PL169273B1 (pl) | 1996-06-28 |
| US20030027317A1 (en) | 2003-02-06 |
| JP2002051791A (ja) | 2002-02-19 |
| US5585258A (en) | 1996-12-17 |
| DE69133402T2 (de) | 2004-11-11 |
| CA2079105A1 (fr) | 1991-10-05 |
| US5585258C1 (en) | 2002-01-15 |
| JP2004073212A (ja) | 2004-03-11 |
| JPH05507612A (ja) | 1993-11-04 |
| AU7675491A (en) | 1991-10-30 |
| US20030064499A1 (en) | 2003-04-03 |
| ES2219637T3 (es) | 2004-12-01 |
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