JP3107784B2 - 光学活性ピペリジン誘導体の酸付加塩及びその製法 - Google Patents

光学活性ピペリジン誘導体の酸付加塩及びその製法

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Publication number
JP3107784B2
JP3107784B2 JP35078497A JP35078497A JP3107784B2 JP 3107784 B2 JP3107784 B2 JP 3107784B2 JP 35078497 A JP35078497 A JP 35078497A JP 35078497 A JP35078497 A JP 35078497A JP 3107784 B2 JP3107784 B2 JP 3107784B2
Authority
JP
Japan
Prior art keywords
chlorophenyl
pyridyl
methoxy
optically active
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP35078497A
Other languages
English (en)
Japanese (ja)
Other versions
JPH10237070A (ja
Inventor
淳一郎 北
寛 藤原
真司 高村
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Ube Corp
Original Assignee
Mitsubishi Tanabe Pharma Corp
Ube Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18393337&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP3107784(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mitsubishi Tanabe Pharma Corp, Ube Industries Ltd filed Critical Mitsubishi Tanabe Pharma Corp
Priority to JP35078497A priority Critical patent/JP3107784B2/ja
Publication of JPH10237070A publication Critical patent/JPH10237070A/ja
Application granted granted Critical
Publication of JP3107784B2 publication Critical patent/JP3107784B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
JP35078497A 1996-12-26 1997-12-19 光学活性ピペリジン誘導体の酸付加塩及びその製法 Expired - Lifetime JP3107784B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP35078497A JP3107784B2 (ja) 1996-12-26 1997-12-19 光学活性ピペリジン誘導体の酸付加塩及びその製法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP34789596 1996-12-26
JP8-347895 1996-12-26
JP35078497A JP3107784B2 (ja) 1996-12-26 1997-12-19 光学活性ピペリジン誘導体の酸付加塩及びその製法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2000032961A Division JP4562229B2 (ja) 1996-12-26 2000-02-10 光学活性ピペリジン誘導体の酸付加塩及びその製法

Publications (2)

Publication Number Publication Date
JPH10237070A JPH10237070A (ja) 1998-09-08
JP3107784B2 true JP3107784B2 (ja) 2000-11-13

Family

ID=18393337

Family Applications (9)

Application Number Title Priority Date Filing Date
JP35078497A Expired - Lifetime JP3107784B2 (ja) 1996-12-26 1997-12-19 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2000032961A Expired - Lifetime JP4562229B2 (ja) 1996-12-26 2000-02-10 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2007000109A Expired - Lifetime JP4704362B2 (ja) 1996-12-26 2007-01-04 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2010264019A Expired - Lifetime JP5360605B2 (ja) 1996-12-26 2010-11-26 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2012098050A Expired - Lifetime JP5518928B2 (ja) 1996-12-26 2012-04-23 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2013201621A Withdrawn JP2014012732A (ja) 1996-12-26 2013-09-27 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2014077266A Withdrawn JP2014169294A (ja) 1996-12-26 2014-04-03 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2015137803A Withdrawn JP2016006059A (ja) 1996-12-26 2015-07-09 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2016170684A Pending JP2017014270A (ja) 1996-12-26 2016-09-01 光学活性ピペリジン誘導体の酸付加塩及びその製法

Family Applications After (8)

Application Number Title Priority Date Filing Date
JP2000032961A Expired - Lifetime JP4562229B2 (ja) 1996-12-26 2000-02-10 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2007000109A Expired - Lifetime JP4704362B2 (ja) 1996-12-26 2007-01-04 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2010264019A Expired - Lifetime JP5360605B2 (ja) 1996-12-26 2010-11-26 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2012098050A Expired - Lifetime JP5518928B2 (ja) 1996-12-26 2012-04-23 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2013201621A Withdrawn JP2014012732A (ja) 1996-12-26 2013-09-27 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2014077266A Withdrawn JP2014169294A (ja) 1996-12-26 2014-04-03 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2015137803A Withdrawn JP2016006059A (ja) 1996-12-26 2015-07-09 光学活性ピペリジン誘導体の酸付加塩及びその製法
JP2016170684A Pending JP2017014270A (ja) 1996-12-26 2016-09-01 光学活性ピペリジン誘導体の酸付加塩及びその製法

Country Status (1)

Country Link
JP (9) JP3107784B2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3107784B2 (ja) * 1996-12-26 2000-11-13 宇部興産株式会社 光学活性ピペリジン誘導体の酸付加塩及びその製法
EP1525884B1 (en) * 2002-07-31 2011-10-12 Senju Pharmaceutical Co., Ltd. Aqueous liquid preparations and light-stabilized aqueous liquid preparations
CA2496623C (en) 2002-08-29 2008-02-12 Taisho Pharmaceutical Co., Ltd. Benzenesulfonate salts of 4-fluoro-2-cyanopyrrolidine derivatives
KR100879409B1 (ko) * 2007-06-11 2009-01-19 한미약품 주식회사 (ｓ)-베포타스틴의 제조방법 및 이에 사용되는 중간체
KR20090061972A (ko) * 2007-12-12 2009-06-17 한미약품 주식회사 베포타스틴 ｐ-톨루엔술폰산염의 결정형, 이의 제조방법 및이를 포함하는 약학 조성물
KR101132949B1 (ko) 2009-09-08 2012-04-10 경희대학교 산학협력단 베포타스틴 살리실산염, 이의 제조방법 및 이를 유효성분으로 포함하는 항히스타민 또는 항알레르기용 약학적 조성물
JP2011195500A (ja) * 2010-03-19 2011-10-06 Tokuyama Corp （ｓ）−４−［４−［（４−クロロフェニル）（２−ピリジル）メトキシ］ピペリジノ］ブタン酸一ベンゼンスルホン酸塩の製造方法
JP5641802B2 (ja) * 2010-07-26 2014-12-17 株式会社トクヤマ （ｓ）−４−〔（４−クロロフェニル）（２−ピリジル）メトキシ〕ピペリジンのジアステレオマー塩の製造方法
KR101232233B1 (ko) 2010-12-08 2013-02-12 (주)팜스웰바이오 (ｓ)-베포타스틴의 제조 방법
JP2012240982A (ja) * 2011-05-23 2012-12-10 Toray Fine Chemicals Co Ltd 光学活性ピペリジン誘導体のベンゼンスルホン酸塩の製造方法
KR101717599B1 (ko) 2015-05-11 2017-03-17 한국화학연구원 신규한 광학분할제 및 이를 이용한 (rs)-베포타스틴의 광학분할방법
CN111116556B (zh) * 2019-12-26 2021-11-02 北京鑫开元医药科技有限公司 一种(r)-2-[(4-氯苯基)(4-哌啶氧基)甲基]吡啶的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0225465A (ja) * 1988-07-15 1990-01-26 Ube Ind Ltd ピペリジン誘導体、その製造方法並びにそれを含む抗ヒスタミン剤
JP2624372B2 (ja) * 1990-11-15 1997-06-25 宇部興産株式会社 ジアリールメトキシピペリジン誘導体
JP2787973B2 (ja) * 1993-05-28 1998-08-20 宇部興産株式会社 ピペリジン中間体の精製法
JPH08333339A (ja) * 1995-06-08 1996-12-17 Fujisawa Pharmaceut Co Ltd 光学活性なピペリジン酢酸誘導体の製造法
JP3107784B2 (ja) * 1996-12-26 2000-11-13 宇部興産株式会社 光学活性ピペリジン誘導体の酸付加塩及びその製法
JPH10182635A (ja) * 1996-12-26 1998-07-07 Ube Ind Ltd 光学活性ピペリジン誘導体及びその製造方法

Also Published As

Publication number Publication date
JP5360605B2 (ja) 2013-12-04
JP2016006059A (ja) 2016-01-14
JP2014012732A (ja) 2014-01-23
JPH10237070A (ja) 1998-09-08
JP2007145852A (ja) 2007-06-14
JP2011063619A (ja) 2011-03-31
JP4704362B2 (ja) 2011-06-15
JP2017014270A (ja) 2017-01-19
JP2000198784A (ja) 2000-07-18
JP5518928B2 (ja) 2014-06-11
JP2012180360A (ja) 2012-09-20
JP2014169294A (ja) 2014-09-18
JP4562229B2 (ja) 2010-10-13

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