JP2025512464A - 筋緊張性ジストロフィーを処置するための筋標的化複合体および製剤 - Google Patents

筋緊張性ジストロフィーを処置するための筋標的化複合体および製剤 Download PDF

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JP2025512464A
JP2025512464A JP2024560666A JP2024560666A JP2025512464A JP 2025512464 A JP2025512464 A JP 2025512464A JP 2024560666 A JP2024560666 A JP 2024560666A JP 2024560666 A JP2024560666 A JP 2024560666A JP 2025512464 A JP2025512464 A JP 2025512464A
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seq
antibody
sequence
formulation
amino acid
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JP2024560666A
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JP2025512464A5 (enExample
Inventor
ヒルダーブランド，スコット
ウィーデン，ティモシー
ナジム，ジョン
ザノッティ，ステファノ
サブラマニアン，ロメシュ，アール．
カタナニ，モハマド，ティー．
デジャルダン，コディ，エー．
タン，キム
クイン，ブレンダン
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Dyne Therapeutics Inc
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Dyne Therapeutics Inc
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Publication of JP2025512464A publication Critical patent/JP2025512464A/ja
Publication of JP2025512464A5 publication Critical patent/JP2025512464A5/ja
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    • A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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JP2024560666A 2022-04-15 2023-04-14 筋緊張性ジストロフィーを処置するための筋標的化複合体および製剤 Pending JP2025512464A (ja)

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US202263331727P 2022-04-15 2022-04-15
US63/331,727 2022-04-15
PCT/US2023/065753 WO2023201318A1 (en) 2022-04-15 2023-04-14 Muscle targeting complexes and formulations for treating myotonic dystrophy

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JP2025512464A true JP2025512464A (ja) 2025-04-17
JP2025512464A5 JP2025512464A5 (enExample) 2026-02-04

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