|
IL154016A0
(en)
|
2000-08-31 |
2003-07-31 |
Pfizer Prod Inc |
Pyrazole derivatives and their use as protein kinase inhibitors
|
|
EP1317450B1
(en)
|
2000-09-15 |
2006-11-22 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
|
NZ526472A
(en)
|
2000-12-21 |
2004-04-30 |
Vertex Pharma |
Pyrazole compounds useful as protein kinase inhibitors
|
|
AU2003286711A1
(en)
|
2002-10-25 |
2004-05-13 |
Vertex Pharmaceuticals Incorporated |
Indazolinone compositions useful as kinase inhibitors
|
|
EP1706400A1
(en)
|
2004-01-09 |
2006-10-04 |
Novartis AG |
Phenyl- 4-(3-phenyl-1h-pyrazol-4-yl)-pyrimidin-2-yl -amine derivatives as igf-ir inhibitors
|
|
US7405220B2
(en)
*
|
2004-06-09 |
2008-07-29 |
Hoffmann-La Roche Inc. |
Pyrazolopyrimidines
|
|
US8362031B2
(en)
|
2004-08-20 |
2013-01-29 |
University Of Kansas |
Lonidamine analogues and treatment of polycystic kidney disease
|
|
CA2598076A1
(en)
|
2005-02-16 |
2006-08-24 |
Astrazeneca Ab |
Chemical compounds
|
|
FR2889526B1
(fr)
|
2005-08-04 |
2012-02-17 |
Aventis Pharma Sa |
7-aza-indazoles substitues, compositions les contenant, procede de fabrication et utilisation
|
|
EP1926734A1
(en)
|
2005-08-22 |
2008-06-04 |
Amgen Inc. |
Pyrazolopyridine and pyrazolopyrimidine compounds useful as kinase enzymes modulators
|
|
WO2008117050A1
(en)
|
2007-03-27 |
2008-10-02 |
Astrazeneca Ab |
Pyrazolyl-amino-substituted pyrazines and their use for the treatment of cancer
|
|
WO2008129255A1
(en)
|
2007-04-18 |
2008-10-30 |
Astrazeneca Ab |
5-aminopyrazol-3-yl-3h-imidazo [4,5-b] pyridine derivatives and their use for the treatment of cancer
|
|
MX2010005950A
(es)
*
|
2007-11-28 |
2010-06-17 |
Schering Corp |
2-fluoropirazolo[1,5-a]pirimidinas como inhibidores de proteina quinasa.
|
|
DE102008063992A1
(de)
|
2008-12-19 |
2010-09-02 |
Lerner, Zinoviy, Dipl.-Ing. |
Neue aliphatisch substituierte Pyrazolopyridine und ihre Verwendung
|
|
KR20110049217A
(ko)
|
2009-11-04 |
2011-05-12 |
다우어드밴스드디스플레이머티리얼 유한회사 |
신규한 유기 발광 화합물 및 이를 채용하고 있는 유기 전계 발광 소자
|
|
EP3795573B1
(en)
|
2009-12-31 |
2022-07-06 |
Hutchison Medipharma Limited |
Certain triazolopyrazines, compositions thereof and methods of use therefor
|
|
JO3145B1
(ar)
|
2010-11-08 |
2017-09-20 |
Lilly Co Eli |
مركبات مفيدة لتثبيط chk1
|
|
KR20120063283A
(ko)
|
2010-12-07 |
2012-06-15 |
제일약품주식회사 |
신규한 피라졸로 피리딘 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 포함하는 약학적 조성물
|
|
WO2013026021A2
(en)
|
2011-08-18 |
2013-02-21 |
Buck Institute For Research On Aging |
Trka as a target for inhibiting app cleavage and/or progression of alzheimer's disease
|
|
WO2014181287A1
(en)
|
2013-05-09 |
2014-11-13 |
Piramal Enterprises Limited |
Heterocyclyl compounds and uses thereof
|
|
NZ714283A
(en)
|
2013-05-10 |
2020-04-24 |
Karus Therapeutics Ltd |
Novel histone deacetylase inhibitors
|
|
CA2918242C
(en)
|
2013-07-31 |
2022-06-21 |
Merck Patent Gmbh |
Pyridines, pyrimidines, and pyrazines, as btk inhibitors and uses thereof
|
|
WO2016057322A1
(en)
|
2014-10-08 |
2016-04-14 |
Salk Institute For Biological Studies |
Ppar agonists and methods of use thereof
|
|
CA2987552A1
(en)
|
2015-06-04 |
2016-12-08 |
Aurigene Discovery Technologies Limited |
Substituted heterocyclyl derivatives as cdk inhibitors
|
|
WO2018106667A1
(en)
|
2016-12-05 |
2018-06-14 |
Microbiotix, Inc. |
Broad-spectrum inhibitors of filoviruses
|
|
WO2019183364A1
(en)
|
2018-03-21 |
2019-09-26 |
Relay Therapeutics, Inc. |
Pyrazolo[3,4-b]pyrazine shp2 phosphatase inhibitors and methods of use thereof
|
|
GB201808093D0
(en)
|
2018-05-18 |
2018-07-04 |
Enterprise Therapeutics Ltd |
Compounds
|
|
WO2020108516A1
(zh)
|
2018-11-27 |
2020-06-04 |
江苏豪森药业集团有限公司 |
含氮杂芳类衍生物调节剂、其制备方法和应用
|
|
JP2022510980A
(ja)
*
|
2018-11-30 |
2022-01-28 |
江▲蘇▼豪森▲薬▼▲業▼集▲団▼有限公司 |
ヘテロ芳香族誘導体調節因子、その製造方法及び使用
|
|
CN113330000B
(zh)
|
2019-01-31 |
2024-12-24 |
辉瑞公司 |
具有对cdk2的抑制活性的3-羰基氨基-5-环戊基-1fi-吡咯化合物
|
|
US20200316064A1
(en)
|
2019-02-15 |
2020-10-08 |
Incyte Corporation |
Cyclin-dependent kinase 2 biomarkers and uses thereof
|
|
WO2020205560A1
(en)
|
2019-03-29 |
2020-10-08 |
Incyte Corporation |
Sulfonylamide compounds as cdk2 inhibitors
|
|
WO2020264420A1
(en)
|
2019-06-28 |
2020-12-30 |
Gb002, Inc. |
Heterocyclic kinase inhibitors and products and uses thereof
|
|
AU2020364007A1
(en)
|
2019-10-11 |
2022-04-28 |
Incyte Corporation |
Bicyclic amines as CDK2 inhibitors
|
|
US11634424B2
(en)
|
2019-11-29 |
2023-04-25 |
Medshine Discovery Inc. |
Diazaindole derivative and use thereof as CHK1 inhibitor
|
|
CN113135896B
(zh)
|
2020-01-18 |
2024-12-06 |
正大天晴药业集团股份有限公司 |
作为ret抑制剂的甲基吡唑类衍生物
|
|
CN114057733A
(zh)
|
2020-08-07 |
2022-02-18 |
海思科医药集团股份有限公司 |
一种并环杂环衍生物及其在医药上的应用
|
|
WO2022061155A1
(en)
|
2020-09-17 |
2022-03-24 |
The Translational Genomics Research Institute |
Imidazopyridazine and imidazopyrazine compounds as inhibitors of cdk7
|
|
TW202246255A
(zh)
|
2021-02-12 |
2022-12-01 |
美商傳達治療有限公司 |
Ｃｄｋ抑制劑及其使用方法
|
|
CN115141195B
(zh)
|
2021-03-03 |
2024-02-06 |
成都先导药物开发股份有限公司 |
一种nuak抑制剂及其用途
|
|
KR20240005751A
(ko)
|
2021-04-12 |
2024-01-12 |
에이2에이 파마수티칼스, 잉크. |
암 치료를 위한 조성물 및 방법
|
|
WO2022245776A1
(en)
|
2021-05-20 |
2022-11-24 |
Saint John's Cancer Institute |
Anti-cdk inhibitors for cancer treatment
|
|
US20240287040A1
(en)
|
2021-06-16 |
2024-08-29 |
Blueprint Medicines Corporation |
Substituted pyrimidinyl-pyrazoles as cdk2 inhibitors
|
|
US11981671B2
(en)
|
2021-06-21 |
2024-05-14 |
Incyte Corporation |
Bicyclic pyrazolyl amines as CDK2 inhibitors
|
|
US11932648B2
(en)
|
2021-06-28 |
2024-03-19 |
Blueprint Medicines Corporation |
CDK2 inhibitors
|
|
WO2023092088A1
(en)
|
2021-11-19 |
2023-05-25 |
Blueprint Medicines Corporation |
Cdk2 inhibitors and methods of making and using same
|
|
WO2023249974A2
(en)
|
2022-06-20 |
2023-12-28 |
Incyclix Bio, Inc. |
Cyclin-dependent kinase 2 inhibitors for medical treatment
|
|
CN117717565A
(zh)
|
2022-09-16 |
2024-03-19 |
北京悦康科创医药科技股份有限公司 |
反义寡核苷酸在制备治疗食管癌药物中的应用
|
|
WO2024148089A1
(en)
|
2023-01-04 |
2024-07-11 |
Blueprint Medicines Corporation |
Cdk2 inhibitors
|
|
WO2024148091A1
(en)
|
2023-01-04 |
2024-07-11 |
Blueprint Medicines Corporation |
Cdk2 inhibitors
|
|
CN120787231A
(zh)
|
2023-01-04 |
2025-10-14 |
缆图药品公司 |
Cdk2抑制剂的固体形式
|
|
EP4646416A1
(en)
|
2023-01-04 |
2025-11-12 |
Blueprint Medicines Corporation |
Cdk2 inhibitors
|
|
EP4661874A1
(en)
|
2023-02-10 |
2025-12-17 |
Blueprint Medicines Corporation |
The cdk2 inhibitor blu-222 for treatment of cancer
|
|
TW202442234A
(zh)
|
2023-04-14 |
2024-11-01 |
美商纜圖藥品公司 |
Ｃｄｋ２抑制劑
|