JP2024508714A - スーパーオキシドジスムターゼ１－（ＳＯＤ１－）関連神経変性疾患を治療または予防するためのスーパーオキシドジスムターゼ１（ＳＯＤ１）ｉＲＮＡ組成物およびその使用方法 - Google Patents

スーパーオキシドジスムターゼ１－（ＳＯＤ１－）関連神経変性疾患を治療または予防するためのスーパーオキシドジスムターゼ１（ＳＯＤ１）ｉＲＮＡ組成物およびその使用方法 Download PDF

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JP2024508714A
JP2024508714A JP2023548609A JP2023548609A JP2024508714A JP 2024508714 A JP2024508714 A JP 2024508714A JP 2023548609 A JP2023548609 A JP 2023548609A JP 2023548609 A JP2023548609 A JP 2023548609A JP 2024508714 A JP2024508714 A JP 2024508714A
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nucleotide sequence
seq
differs
nucleotides
antisense strand
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JP2024508714A5 (https=
Inventor
カストレノ，アダム
ギルバート，ジェイソン
カイタニス，チャラランボス
ディ マキニンチ，ジェイムズ
ミルスタイン，スチュアート
ケイ シュリーゲル，マーク
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Alnylam Pharmaceuticals Inc
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Alnylam Pharmaceuticals Inc
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JP2023548609A 2021-02-12 2022-02-11 スーパーオキシドジスムターゼ１－（ＳＯＤ１－）関連神経変性疾患を治療または予防するためのスーパーオキシドジスムターゼ１（ＳＯＤ１）ｉＲＮＡ組成物およびその使用方法 Pending JP2024508714A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163148991P 2021-02-12 2021-02-12
US63/148,991 2021-02-12
US202163270176P 2021-10-21 2021-10-21
US63/270,176 2021-10-21
PCT/US2022/016046 WO2022174000A2 (en) 2021-02-12 2022-02-11 Superoxide dismutase 1 (sod1) irna compositions and methods of use thereof for treating or preventing superoxide dismutase 1- (sod1-) associated neurodegenerative diseases

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JP2024508714A true JP2024508714A (ja) 2024-02-28
JP2024508714A5 JP2024508714A5 (https=) 2025-02-20

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JP2023548609A Pending JP2024508714A (ja) 2021-02-12 2022-02-11 スーパーオキシドジスムターゼ１－（ＳＯＤ１－）関連神経変性疾患を治療または予防するためのスーパーオキシドジスムターゼ１（ＳＯＤ１）ｉＲＮＡ組成物およびその使用方法

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US (2) US11649459B2 (https=)
EP (1) EP4291654A2 (https=)
JP (1) JP2024508714A (https=)
KR (1) KR20230146048A (https=)
AU (1) AU2022220704A1 (https=)
BR (1) BR112023015761A2 (https=)
CA (1) CA3210763A1 (https=)
IL (1) IL304880A (https=)
MX (1) MX2023009324A (https=)
TW (1) TW202305131A (https=)
WO (1) WO2022174000A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025522433A (ja) 2022-06-15 2025-07-15 アローヘッド ファーマシューティカルズ インコーポレイテッド スーパーオキシドジスムターゼ１（ＳＯＤ１）の発現を阻害するためのＲＮＡｉ剤、その組成物、及び使用の方法
WO2024216109A1 (en) * 2023-04-12 2024-10-17 Alnylam Pharmaceuticals, Inc. Formulations for oligonucleotide delivery
CN121335980A (zh) * 2023-05-26 2026-01-13 阿达尔克斯制药有限公司 Sod1调节组合物及其使用方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019217459A1 (en) * 2018-05-07 2019-11-14 Alnylam Pharmaceuticals, Inc. Extrahepatic delivery

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