TW202305131A - 用於治療或預防超氧歧化酶１－（ＳＯＤ１－）相關的神經退化疾病的超氧歧化酶１（ＳＯＤ１）ｉＲＮＡ組成物及其使用方法 - Google Patents

用於治療或預防超氧歧化酶１－（ＳＯＤ１－）相關的神經退化疾病的超氧歧化酶１（ＳＯＤ１）ｉＲＮＡ組成物及其使用方法 Download PDF

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TW202305131A
TW202305131A TW111105127A TW111105127A TW202305131A TW 202305131 A TW202305131 A TW 202305131A TW 111105127 A TW111105127 A TW 111105127A TW 111105127 A TW111105127 A TW 111105127A TW 202305131 A TW202305131 A TW 202305131A
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nucleotide sequence
seq
nucleotides
antisense strand
differs
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TW111105127A
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Chinese (zh)
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艾登 卡斯特瑞諾
傑森 吉柏爾
恰拉蘭波斯 凱坦尼斯
詹姆斯Ｄ 麥克尼奇
史特爾 米史坦
馬克Ｋ 史奇蓋爾
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美商艾拉倫製藥股份有限公司
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TW111105127A 2021-02-12 2022-02-11 用於治療或預防超氧歧化酶１－（ＳＯＤ１－）相關的神經退化疾病的超氧歧化酶１（ＳＯＤ１）ｉＲＮＡ組成物及其使用方法 TW202305131A (zh)

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US202163148991P 2021-02-12 2021-02-12
US63/148,991 2021-02-12
US202163270176P 2021-10-21 2021-10-21
US63/270,176 2021-10-21

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US (2) US11649459B2 (https=)
EP (1) EP4291654A2 (https=)
JP (1) JP2024508714A (https=)
KR (1) KR20230146048A (https=)
AU (1) AU2022220704A1 (https=)
BR (1) BR112023015761A2 (https=)
CA (1) CA3210763A1 (https=)
IL (1) IL304880A (https=)
MX (1) MX2023009324A (https=)
TW (1) TW202305131A (https=)
WO (1) WO2022174000A2 (https=)

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EP4540390A2 (en) 2022-06-15 2025-04-23 Arrowhead Pharmaceuticals, Inc. Rnai agents for inhibiting expression of superoxide dismutase 1 (sod1), compositions thereof, and methods of use
TW202446402A (zh) * 2023-04-12 2024-12-01 美商艾拉倫製藥公司 用於寡核苷酸遞送之調配物
IL324720A (en) * 2023-05-26 2026-01-01 Adarx Pharmaceuticals Inc SOD1 modulators and methods of using them

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