JP2024503609A5 - - Google Patents

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Publication number
JP2024503609A5
JP2024503609A5 JP2023540474A JP2023540474A JP2024503609A5 JP 2024503609 A5 JP2024503609 A5 JP 2024503609A5 JP 2023540474 A JP2023540474 A JP 2023540474A JP 2023540474 A JP2023540474 A JP 2023540474A JP 2024503609 A5 JP2024503609 A5 JP 2024503609A5
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Japan
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seq
amino acid
methyl
acid sequence
nucleoside
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JP2023540474A
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Japanese (ja)
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JP7804685B2 (ja
JP2024503609A (ja
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Priority claimed from PCT/US2021/065628 external-priority patent/WO2022147209A1/en
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JP2023540474A 2020-12-31 2021-12-30 筋緊張性ジストロフィーを処置するための筋標的化複合体およびその使用 Active JP7804685B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063133013P 2020-12-31 2020-12-31
US63/133,013 2020-12-31
US202163179100P 2021-04-23 2021-04-23
US63/179,100 2021-04-23
US202163245262P 2021-09-17 2021-09-17
US63/245,262 2021-09-17
PCT/US2021/065628 WO2022147209A1 (en) 2020-12-31 2021-12-30 Muscle targeting complexes and uses thereof for treating myotonic dystrophy

Publications (3)

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JP2024503609A JP2024503609A (ja) 2024-01-26
JP2024503609A5 true JP2024503609A5 (https=) 2025-01-10
JP7804685B2 JP7804685B2 (ja) 2026-01-22

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JP2023540474A Active JP7804685B2 (ja) 2020-12-31 2021-12-30 筋緊張性ジストロフィーを処置するための筋標的化複合体およびその使用

Country Status (9)

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US (1) US20240117356A1 (https=)
EP (1) EP4271816A4 (https=)
JP (1) JP7804685B2 (https=)
KR (1) KR20230128050A (https=)
AU (1) AU2021414227A1 (https=)
CA (1) CA3202832A1 (https=)
IL (1) IL304048A (https=)
MX (1) MX2023007881A (https=)
WO (1) WO2022147209A1 (https=)

Families Citing this family (18)

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CA3108282A1 (en) 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
SG11202100928QA (en) 2018-08-02 2021-02-25 Dyne Therapeutics Inc Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
JP2024525608A (ja) 2021-07-09 2024-07-12 ダイン セラピューティクス,インコーポレーテッド ジストロフィン異常症を処置するための筋標的化複合体および製剤
US11638761B2 (en) 2021-07-09 2023-05-02 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
US11771776B2 (en) 2021-07-09 2023-10-03 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11633498B2 (en) 2021-07-09 2023-04-25 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US11672872B2 (en) 2021-07-09 2023-06-13 Dyne Therapeutics, Inc. Anti-transferrin receptor antibody and uses thereof
WO2023034409A1 (en) 2021-09-01 2023-03-09 Biogen Ma Inc. Anti-transferrin receptor antibodies and uses thereof
IL316143A (en) 2022-04-15 2024-12-01 Dyne Therapeutics Inc Muscle targeting complexes and formulations for the treatment of myotonic dystrophy
EP4562157A1 (en) * 2022-07-28 2025-06-04 New York University Targeting long non-coding rna chromr in interferon-mediated inflammation in humans
WO2024257848A1 (ja) * 2023-06-16 2024-12-19 ルクサナバイオテク株式会社 遅発性中枢毒性が低減されているアンチセンスオリゴヌクレオチドの設計方法、及びその製造方法
WO2025147541A1 (en) * 2024-01-02 2025-07-10 Dyne Therapeutics, Inc. Methods and compositions for treating myotonic dystrophy

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JP2023535078A (ja) * 2020-07-23 2023-08-15 ダイン セラピューティクス,インコーポレーテッド 筋緊張性ジストロフィーを処置するための筋標的化複合体およびその使用

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