JP2021532832A5 - - Google Patents
Info
- Publication number
- JP2021532832A5 JP2021532832A5 JP2021529256A JP2021529256A JP2021532832A5 JP 2021532832 A5 JP2021532832 A5 JP 2021532832A5 JP 2021529256 A JP2021529256 A JP 2021529256A JP 2021529256 A JP2021529256 A JP 2021529256A JP 2021532832 A5 JP2021532832 A5 JP 2021532832A5
- Authority
- JP
- Japan
- Prior art keywords
- complex according
- oligonucleotide
- transferrin receptor
- complex
- fxn
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862714035P | 2018-08-02 | 2018-08-02 | |
| US62/714,035 | 2018-08-02 | ||
| PCT/US2019/044959 WO2020028840A1 (en) | 2018-08-02 | 2019-08-02 | Muscle targeting complexes and uses thereof for treating friedreich's ataxia |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021532832A JP2021532832A (ja) | 2021-12-02 |
| JP2021532832A5 true JP2021532832A5 (https=) | 2022-08-10 |
| JPWO2020028840A5 JPWO2020028840A5 (https=) | 2022-08-10 |
Family
ID=69232074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021529256A Pending JP2021532832A (ja) | 2018-08-02 | 2019-08-02 | フリートライヒ運動失調症を処置するための筋標的化複合体およびそれらの使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20210308274A1 (https=) |
| EP (1) | EP3830131A4 (https=) |
| JP (1) | JP2021532832A (https=) |
| KR (1) | KR20210086601A (https=) |
| CN (1) | CN113166240A (https=) |
| CA (1) | CA3108386A1 (https=) |
| EA (1) | EA202190419A1 (https=) |
| IL (1) | IL280535A (https=) |
| WO (1) | WO2020028840A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11168141B2 (en) | 2018-08-02 | 2021-11-09 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US11911484B2 (en) | 2018-08-02 | 2024-02-27 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| EP3829595A4 (en) | 2018-08-02 | 2022-08-24 | Dyne Therapeutics, Inc. | MUSCLE-DIRECTED COMPLEXES AND USES THEREOF IN THE TREATMENT OF DYSTROPHINOPATHIES |
| US12097263B2 (en) | 2018-08-02 | 2024-09-24 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US12018087B2 (en) | 2018-08-02 | 2024-06-25 | Dyne Therapeutics, Inc. | Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject |
| US20220193250A1 (en) | 2018-08-02 | 2022-06-23 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US12370264B1 (en) | 2018-08-02 | 2025-07-29 | Dyne Therapeutics, Inc. | Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject |
| CN118251238A (zh) * | 2021-06-21 | 2024-06-25 | 达因疗法公司 | 肌肉靶向复合物及其用于治疗弗里德赖希共济失调的用途 |
| US11771776B2 (en) | 2021-07-09 | 2023-10-03 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| IL309936A (en) | 2021-07-09 | 2024-03-01 | Dyne Therapeutics Inc | Muscle targeting complexes and formulations for the treatment of dystrophinopathy |
| US11638761B2 (en) | 2021-07-09 | 2023-05-02 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy |
| US11969475B2 (en) | 2021-07-09 | 2024-04-30 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US11672872B2 (en) | 2021-07-09 | 2023-06-13 | Dyne Therapeutics, Inc. | Anti-transferrin receptor antibody and uses thereof |
| US11633498B2 (en) | 2021-07-09 | 2023-04-25 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| EP4396231A1 (en) | 2021-09-01 | 2024-07-10 | Biogen MA Inc. | Anti-transferrin receptor antibodies and uses thereof |
| US20250339553A1 (en) | 2022-04-15 | 2025-11-06 | Dyne Therapeutics, Inc. | Muscle targeting complexes and formulations for treating myotonic dystrophy |
| IL320016A (en) * | 2022-11-04 | 2025-06-01 | Regeneron Pharma | Calcium voltage-gated channel auxiliary subunit gamma 1 (cacng1) binding proteins and cacng1-mediated delivery to skeletal muscle |
| WO2025160275A1 (en) | 2024-01-24 | 2025-07-31 | Arrowhead Pharmaceuticals, Inc. | Anti-transferrin receptor antibodies, conjugates thereof, and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3033425A4 (en) * | 2013-08-16 | 2017-07-26 | Rana Therapeutics, Inc. | Compositions and methods for modulating expression of frataxin |
| CA2921457A1 (en) * | 2013-08-16 | 2015-02-19 | Rana Therapeutics, Inc. | Heterochromatin forming non-coding rnas |
| EP3221362B1 (en) * | 2014-11-19 | 2019-07-24 | F.Hoffmann-La Roche Ag | Anti-transferrin receptor antibodies and methods of use |
| US20190002876A1 (en) * | 2014-12-09 | 2019-01-03 | The Board Of Regents Of The University Of Texas System | Compositions and methods for treatment of friedreich's ataxia |
| RU2021102893A (ru) * | 2015-11-05 | 2021-03-03 | Бамбу Терапьютикс, Инк. | Модифицированные гены атаксии фридрейха и векторы для генной терапии |
| CN109310765A (zh) * | 2016-06-20 | 2019-02-05 | 领先基因生物技术股份有限公司 | 抗体-药物偶联物 |
| JP7576542B2 (ja) * | 2018-08-02 | 2024-10-31 | ダイン セラピューティクス，インコーポレーテッド | 筋標的化複合体およびそれらの使用 |
-
2019
- 2019-08-02 KR KR1020217006029A patent/KR20210086601A/ko not_active Withdrawn
- 2019-08-02 EA EA202190419A patent/EA202190419A1/ru unknown
- 2019-08-02 JP JP2021529256A patent/JP2021532832A/ja active Pending
- 2019-08-02 CA CA3108386A patent/CA3108386A1/en active Pending
- 2019-08-02 EP EP19845433.2A patent/EP3830131A4/en active Pending
- 2019-08-02 US US17/265,019 patent/US20210308274A1/en not_active Abandoned
- 2019-08-02 WO PCT/US2019/044959 patent/WO2020028840A1/en not_active Ceased
- 2019-08-02 CN CN201980064588.8A patent/CN113166240A/zh active Pending
-
2021
- 2021-01-31 IL IL280535A patent/IL280535A/en unknown
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