JP2024546436A5 - - Google Patents
Info
- Publication number
- JP2024546436A5 JP2024546436A5 JP2024527763A JP2024527763A JP2024546436A5 JP 2024546436 A5 JP2024546436 A5 JP 2024546436A5 JP 2024527763 A JP2024527763 A JP 2024527763A JP 2024527763 A JP2024527763 A JP 2024527763A JP 2024546436 A5 JP2024546436 A5 JP 2024546436A5
- Authority
- JP
- Japan
- Prior art keywords
- complex according
- oligonucleotide
- tfr1
- optionally
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163278993P | 2021-11-12 | 2021-11-12 | |
| US202163278882P | 2021-11-12 | 2021-11-12 | |
| US63/278,882 | 2021-11-12 | ||
| US63/278,993 | 2021-11-12 | ||
| US202263312633P | 2022-02-22 | 2022-02-22 | |
| US202263312617P | 2022-02-22 | 2022-02-22 | |
| US63/312,617 | 2022-02-22 | ||
| US63/312,633 | 2022-02-22 | ||
| PCT/US2022/079604 WO2023086864A1 (en) | 2021-11-12 | 2022-11-10 | Muscle targeting complexes for treating facioscapulohumeral muscular dystrophy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024546436A JP2024546436A (ja) | 2024-12-24 |
| JP2024546436A5 true JP2024546436A5 (https=) | 2025-11-18 |
Family
ID=86336621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024527763A Pending JP2024546436A (ja) | 2021-11-12 | 2022-11-10 | 顔面肩甲上腕筋ジストロフィーを処置するための筋標的化複合体およびそれらの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20250025570A1 (https=) |
| EP (1) | EP4429711A1 (https=) |
| JP (1) | JP2024546436A (https=) |
| KR (1) | KR20240099448A (https=) |
| CA (1) | CA3234136A1 (https=) |
| IL (1) | IL312170A (https=) |
| WO (1) | WO2023086864A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3108282A1 (en) | 2018-08-02 | 2020-02-06 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US11911484B2 (en) | 2018-08-02 | 2024-02-27 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| SG11202100928QA (en) | 2018-08-02 | 2021-02-25 | Dyne Therapeutics Inc | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US12018087B2 (en) | 2018-08-02 | 2024-06-25 | Dyne Therapeutics, Inc. | Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject |
| US12097263B2 (en) | 2018-08-02 | 2024-09-24 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
| US11168141B2 (en) | 2018-08-02 | 2021-11-09 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US12370264B1 (en) | 2018-08-02 | 2025-07-29 | Dyne Therapeutics, Inc. | Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject |
| US11771776B2 (en) | 2021-07-09 | 2023-10-03 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating dystrophinopathies |
| US11969475B2 (en) | 2021-07-09 | 2024-04-30 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| US11638761B2 (en) | 2021-07-09 | 2023-05-02 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy |
| JP2024525608A (ja) | 2021-07-09 | 2024-07-12 | ダイン セラピューティクス，インコーポレーテッド | ジストロフィン異常症を処置するための筋標的化複合体および製剤 |
| IL316143A (en) | 2022-04-15 | 2024-12-01 | Dyne Therapeutics Inc | Muscle targeting complexes and formulations for the treatment of myotonic dystrophy |
| AU2024299328A1 (en) | 2023-07-21 | 2026-01-22 | Marrow Therapeutics, Inc. | Hematopoietic cell targeting conjugates and related methods |
| WO2025259503A1 (en) * | 2024-06-12 | 2025-12-18 | Dyne Therapeutics, Inc. | Biomarkers for facioscapulohumeral muscular dystrophy |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3192880B1 (en) * | 2010-08-18 | 2019-10-09 | Fred Hutchinson Cancer Research Center | Nucleic acid agents for use in treating facioscapulohumeral dystrophy (fshd) |
| SG11202100928QA (en) * | 2018-08-02 | 2021-02-25 | Dyne Therapeutics Inc | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| AU2021206234A1 (en) * | 2020-01-10 | 2022-09-01 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating myotonic dystrophy |
-
2022
- 2022-11-10 WO PCT/US2022/079604 patent/WO2023086864A1/en not_active Ceased
- 2022-11-10 CA CA3234136A patent/CA3234136A1/en active Pending
- 2022-11-10 IL IL312170A patent/IL312170A/en unknown
- 2022-11-10 EP EP22893831.2A patent/EP4429711A1/en active Pending
- 2022-11-10 JP JP2024527763A patent/JP2024546436A/ja active Pending
- 2022-11-10 KR KR1020247019054A patent/KR20240099448A/ko active Pending
- 2022-11-10 US US18/708,815 patent/US20250025570A1/en active Pending
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