JP2023512442A5 - - Google Patents

Info

Publication number
JP2023512442A5
JP2023512442A5 JP2022542486A JP2022542486A JP2023512442A5 JP 2023512442 A5 JP2023512442 A5 JP 2023512442A5 JP 2022542486 A JP2022542486 A JP 2022542486A JP 2022542486 A JP2022542486 A JP 2022542486A JP 2023512442 A5 JP2023512442 A5 JP 2023512442A5
Authority
JP
Japan
Prior art keywords
cdr
seq
complex according
complex
oligonucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022542486A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023512442A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/012719 external-priority patent/WO2021142275A1/en
Publication of JP2023512442A publication Critical patent/JP2023512442A/ja
Publication of JP2023512442A5 publication Critical patent/JP2023512442A5/ja
Pending legal-status Critical Current

Links

JP2022542486A 2020-01-10 2021-01-08 顔面肩甲上腕型筋ジストロフィーを処置するための筋標的化複合体およびそれらの使用 Pending JP2023512442A (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US202062959788P 2020-01-10 2020-01-10
US62/959,788 2020-01-10
US202062965740P 2020-01-24 2020-01-24
US62/965,740 2020-01-24
US202062968761P 2020-01-31 2020-01-31
US62/968,761 2020-01-31
US202063055513P 2020-07-23 2020-07-23
US63/055,513 2020-07-23
US202063061833P 2020-08-06 2020-08-06
US63/061,833 2020-08-06
US202063132929P 2020-12-31 2020-12-31
US63/132,929 2020-12-31
PCT/US2021/012719 WO2021142275A1 (en) 2020-01-10 2021-01-08 Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy

Publications (2)

Publication Number Publication Date
JP2023512442A JP2023512442A (ja) 2023-03-27
JP2023512442A5 true JP2023512442A5 (https=) 2024-01-17

Family

ID=76788742

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022542486A Pending JP2023512442A (ja) 2020-01-10 2021-01-08 顔面肩甲上腕型筋ジストロフィーを処置するための筋標的化複合体およびそれらの使用

Country Status (11)

Country Link
US (1) US20230088865A1 (https=)
EP (1) EP4087924A4 (https=)
JP (1) JP2023512442A (https=)
KR (1) KR20220125801A (https=)
CN (1) CN115349013B (https=)
AU (1) AU2021205492A1 (https=)
BR (1) BR112022013603A2 (https=)
CA (1) CA3163299A1 (https=)
IL (1) IL294480A (https=)
MX (1) MX2022008538A (https=)
WO (1) WO2021142275A1 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202100928QA (en) 2018-08-02 2021-02-25 Dyne Therapeutics Inc Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
CA3108282A1 (en) 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
JP7780691B2 (ja) * 2020-01-10 2025-12-05 ダイン セラピューティクス,インコーポレーテッド ジストロフィン異常症を処置するための筋標的化複合体およびそれらの使用
AU2021206234A1 (en) * 2020-01-10 2022-09-01 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
WO2021188390A1 (en) 2020-03-19 2021-09-23 Avidity Biosciences, Inc. Compositions and methods of treating facioscapulohumeral muscular dystrophy
KR20230023612A (ko) 2020-04-02 2023-02-17 마이레큘, 인크. 조작된 올리고뉴클레오티드를 사용한 표적화된 억제
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
JP2024525608A (ja) 2021-07-09 2024-07-12 ダイン セラピューティクス,インコーポレーテッド ジストロフィン異常症を処置するための筋標的化複合体および製剤
US11771776B2 (en) 2021-07-09 2023-10-03 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11638761B2 (en) 2021-07-09 2023-05-02 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
US11633498B2 (en) 2021-07-09 2023-04-25 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US11672872B2 (en) 2021-07-09 2023-06-13 Dyne Therapeutics, Inc. Anti-transferrin receptor antibody and uses thereof
CN118265544A (zh) 2021-09-16 2024-06-28 艾维迪提生物科学公司 治疗面肩肱型肌营养不良的组合物和方法
AU2022377070A1 (en) * 2021-11-01 2024-04-11 Dyne Therapeutics, Inc. Muscle targeting complexes for treating dystrophinopathies
TW202345894A (zh) * 2022-01-07 2023-12-01 美商密瑞克公司 靶向表現於肌肉細胞表面的蛋白質之組織特異性顯像及治療劑
IL316143A (en) 2022-04-15 2024-12-01 Dyne Therapeutics Inc Muscle targeting complexes and formulations for the treatment of myotonic dystrophy
AU2024299328A1 (en) 2023-07-21 2026-01-22 Marrow Therapeutics, Inc. Hematopoietic cell targeting conjugates and related methods
WO2025160275A1 (en) 2024-01-24 2025-07-31 Arrowhead Pharmaceuticals, Inc. Anti-transferrin receptor antibodies, conjugates thereof, and uses thereof

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
US7241444B2 (en) * 2002-01-18 2007-07-10 Pierre Fabre Medicament Anti-IGF-IR antibodies and uses thereof
EP2736539B1 (en) * 2011-07-25 2017-08-23 Nationwide Children's Hospital, Inc. Recombinant virus products and methods for inhibition of expression of dux4
WO2013120038A2 (en) * 2012-02-10 2013-08-15 Regents Of The University Of Minnesota Morpholino targeting dux4 for treating fshd
BR112014020826A8 (pt) * 2012-02-24 2017-09-19 Stem Centrx Inc Anticorpo que se liga especificamente a um epítopo, ácido nucleico, vetor ou célula hospedeira, conjugado de fármaco – anticorpo, composição farmacêutica compreendendo o referido anticorpo, uso do mesmo, kit e método de preparação do conjugado
EP2961770A1 (en) * 2013-02-26 2016-01-06 Roche Glycart AG Bispecific t cell activating antigen binding molecules
DK3473270T5 (da) * 2016-06-20 2024-09-09 Genahead Bio Inc Konjugat af antistof-lægemiddel
MX2019008199A (es) * 2017-01-06 2019-11-25 Avidity Biosciences Llc Composiciones de acido nucleico polipeptido y metodos de induccion de la omision de exon.
MX2020003130A (es) * 2017-09-22 2020-09-25 Avidity Biosciences Inc Composiciones y metodos de induccion de salto de exon en acidos nucleicos-polipeptidos.
AU2018378812B2 (en) * 2017-12-06 2025-05-22 Avidity Biosciences, Inc. Compositions and methods of treating muscle atrophy and myotonic dystrophy
SG11202100928QA (en) * 2018-08-02 2021-02-25 Dyne Therapeutics Inc Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy

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